2c5c - Revision history

OCA at 14:06, 13 December 2023

OCA — Wed, 13 Dec 2023 14:06:26 GMT

←Older revision		Revision as of 14:06, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2c5c' size='340' side='right'caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>		<StructureSection load='2c5c' size='340' side='right'caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bph30 Bph30~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2C5C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C5C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4~~</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL~~</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.94Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [~~http~~://pdbe.org/2c5c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2c5c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2c5c ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [https://pdbe.org/2c5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [https://www.ebi.ac.uk/pdbsum/2c5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c5c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~STXB_BPH19 STXB_BPH19]~~] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.	+	[https://www.uniprot.org/uniprot/STXB_BPH30 STXB_BPH30] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 22:

	==See Also==		==See Also==
-	*[[Shiga toxin\|Shiga toxin]]	+	*[[Shiga toxin 3D structures\|Shiga toxin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bph30]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Dodd, R B~~]]	+	[[Category: Phage h30]]
-	[[Category: ~~Read, R J~~]]	+	[[Category: Dodd RB]]
-	[[Category: ~~Bacterial exotoxin]]~~	+	[[Category: Read RJ]]
-	~~[[Category: Bivalent ligand]]~~	+
-	~~[[Category: Gb3 binding activity]]~~	+
-	~~[[Category: Ob fold]]~~	+
-	~~[[Category: Protein-carbohydrate recognition]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 11:48, 23 September 2020

OCA — Wed, 23 Sep 2020 11:48:17 GMT

←Older revision		Revision as of 11:48, 23 September 2020
Line 1:		Line 1:

	==Shiga-like toxin 1 B subunit complexed with a bivalent inhibitor==		==Shiga-like toxin 1 B subunit complexed with a bivalent inhibitor==
-	<StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>	+	<StructureSection load='2c5c' size='340' side='right'caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bph30 Bph30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2C5C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bph30 Bph30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2C5C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC~~</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL~~</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://pdbe.org/2c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c5c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://pdbe.org/2c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c5c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Bph30]]		[[Category: Bph30]]
		+	[[Category: Large Structures]]
	[[Category: Dodd, R B]]		[[Category: Dodd, R B]]
	[[Category: Read, R J]]		[[Category: Read, R J]]

OCA at 08:29, 23 May 2018

OCA — Wed, 23 May 2018 08:29:33 GMT

←Older revision		Revision as of 08:29, 23 May 2018
Line 1:		Line 1:
-	==~~SHIGA~~-~~LIKE TOXIN~~ 1 B ~~SUBUNIT COMPLEXED WITH A BIVALENT INHIBITOR~~==	+
		+	==Shiga-like toxin 1 B subunit complexed with a bivalent inhibitor==
	<StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>		<StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bph30 Bph30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br>		<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bph30 Bph30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4~~</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://pdbe.org/2c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://pdbe.org/2c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c5c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/2c5c_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/2c5c_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c5c ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 13:55, 11 September 2015

OCA — Fri, 11 Sep 2015 13:55:24 GMT

←Older revision		Revision as of 13:55, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>		<StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Phage_h30 Phage h30~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bph30 Bph30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://pdbe.org/2c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~SLTB_BPH19 SLTB_BPH19~~]] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.	+	[[http://www.uniprot.org/uniprot/STXB_BPH19 STXB_BPH19]] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Phage h30~~]]	+	[[Category: Bph30]]
	[[Category: Dodd, R B]]		[[Category: Dodd, R B]]
	[[Category: Read, R J]]		[[Category: Read, R J]]

OCA at 17:22, 25 December 2014

OCA — Thu, 25 Dec 2014 17:22:13 GMT

←Older revision		Revision as of 17:22, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br>		<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SLTB_BPH19 SLTB_BPH19]] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Phage h30]]		[[Category: Phage h30]]
-	[[Category: Dodd, R B.]]	+	[[Category: Dodd, R B]]
-	[[Category: Read, R J.]]	+	[[Category: Read, R J]]
	[[Category: Bacterial exotoxin]]		[[Category: Bacterial exotoxin]]
	[[Category: Bivalent ligand]]		[[Category: Bivalent ligand]]

OCA at 04:43, 29 September 2014

OCA — Mon, 29 Sep 2014 04:43:21 GMT

←Older revision		Revision as of 04:43, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:2c5c.png\|left\|200px]]~~	+	==SHIGA-LIKE TOXIN 1 B SUBUNIT COMPLEXED WITH A BIVALENT INHIBITOR==
-		+	<StructureSection load='2c5c' size='340' side='right' caption='[[2c5c]], [[Resolution\|resolution]] 2.94Å' scene=''>
-	~~{{STRUCTURE_2c5c\| PDB=2c5c \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C5C FirstGlance]. <br>
-	===SHIGA-LIKE TOXIN 1 B SUBUNIT COMPLEXED WITH A BIVALENT INHIBITOR===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=S10:DIETHYL+PROPANE-1,3-DIYLBISCARBAMATE'>S10</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene><br>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c5c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c5c RCSB], [http://www.ebi.ac.uk/pdbsum/2c5c PDBsum]</span></td></tr>
-		+	<table>
-	==~~About this Structure~~==	+	== Evolutionary Conservation ==
-	[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA].	+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/2c5c_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Shiga toxin\|Shiga toxin]]		*[[Shiga toxin\|Shiga toxin]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Phage h30]]		[[Category: Phage h30]]
	[[Category: Dodd, R B.]]		[[Category: Dodd, R B.]]

OCA at 19:23, 20 October 2012

OCA — Sat, 20 Oct 2012 19:23:41 GMT

←Older revision		Revision as of 19:23, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2c5c]] is a 10 chain structure ~~of [[Shiga toxin]]~~ with sequence from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA].	+	[[2c5c]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA].

	==See Also==		==See Also==

OCA: Protected "2c5c" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 07:12:12 GMT

Protected "2c5c" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:12, 27 July 2012

OCA at 07:12, 27 July 2012

OCA — Fri, 27 Jul 2012 07:12:10 GMT

←Older revision		Revision as of 07:12, 27 July 2012
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-	{{Seed}}
	[[Image:2c5c.png\|left\|200px]]		[[Image:2c5c.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2c5c", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2c5c\| PDB=2c5c \| SCENE= }}		{{STRUCTURE_2c5c\| PDB=2c5c \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~2C5C~~ is a 10 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA].	+	[[2c5c]] is a 10 chain structure of [[Shiga toxin]] with sequence from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA].
		+
		+	==See Also==
		+	*[[Shiga toxin\|Shiga toxin]]
	[[Category: Phage h30]]		[[Category: Phage h30]]
	[[Category: Dodd, R B.]]		[[Category: Dodd, R B.]]
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	[[Category: Protein-carbohydrate recognition]]		[[Category: Protein-carbohydrate recognition]]
	[[Category: Toxin]]		[[Category: Toxin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:04:20 2009''

OCA at 22:04, 17 February 2009

OCA — Tue, 17 Feb 2009 22:04:21 GMT

←Older revision		Revision as of 22:04, 17 February 2009
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-	[[Image:2c5c.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2c5c.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2c5c\| PDB=2c5c \| SCENE= }}		{{STRUCTURE_2c5c\| PDB=2c5c \| SCENE= }}

-	~~'''~~SHIGA-LIKE TOXIN 1 B SUBUNIT COMPLEXED WITH A BIVALENT INHIBITOR~~'''~~	+	===SHIGA-LIKE TOXIN 1 B SUBUNIT COMPLEXED WITH A BIVALENT INHIBITOR===


	==About this Structure==		==About this Structure==
-	2C5C is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA].	+	2C5C is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5C OCA].
	[[Category: Phage h30]]		[[Category: Phage h30]]
-	[[Category: Single protein]]
	[[Category: Dodd, R B.]]		[[Category: Dodd, R B.]]
	[[Category: Read, R J.]]		[[Category: Read, R J.]]
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	[[Category: Protein-carbohydrate recognition]]		[[Category: Protein-carbohydrate recognition]]
	[[Category: Toxin]]		[[Category: Toxin]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sat May 3 21~~:16:~~39 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:04:20 2009''