2c99 - Revision history

OCA at 14:10, 13 December 2023

OCA — Wed, 13 Dec 2023 14:10:04 GMT

←Older revision		Revision as of 14:10, 13 December 2023
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	<StructureSection load='2c99' size='340' side='right'caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2c99' size='340' side='right'caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C99 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C99 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID~~-~~ADENYLATE+ESTER'>ANP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [https://pdbe.org/2c99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [https://www.ebi.ac.uk/pdbsum/2c99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c99 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [https://pdbe.org/2c99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [https://www.ebi.ac.uk/pdbsum/2c99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c99 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PSPF_ECOLI PSPF_ECOLI]] Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene.<ref>PMID:8606168</ref> <ref>PMID:15485810</ref> <ref>PMID:19804784</ref>	+	[https://www.uniprot.org/uniprot/PSPF_ECOLI PSPF_ECOLI] Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene.<ref>PMID:8606168</ref> <ref>PMID:15485810</ref> <ref>PMID:19804784</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Buck, M]]	+	[[Category: Buck M]]
-	[[Category: Niwa, H]]	+	[[Category: Niwa H]]
-	[[Category: Rappas, M]]	+	[[Category: Rappas M]]
-	[[Category: Schumacher, J]]	+	[[Category: Schumacher J]]
-	[[Category: Zhang, X]]	+	[[Category: Zhang X]]
-	~~[[Category: Atp-binding]]~~	+
-	~~[[Category: Atpase]]~~	+
-	~~[[Category: Bacterial sigma54 activator]]~~	+
-	~~[[Category: Dna-binding]]~~	+
-	~~[[Category: Sensory transduction]]~~	+
-	~~[[Category: Transcription regulation]]~~	+
-	~~[[Category: Two-component regulatory system~~]]	+

OCA at 06:50, 1 December 2021

OCA — Wed, 01 Dec 2021 06:50:51 GMT

←Older revision		Revision as of 06:50, 1 December 2021
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	<StructureSection load='2c99' size='340' side='right'caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2c99' size='340' side='right'caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2C99 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C99 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [~~http~~://pdbe.org/2c99 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2c99 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2c99 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [https://pdbe.org/2c99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [https://www.ebi.ac.uk/pdbsum/2c99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c99 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PSPF_ECOLI PSPF_ECOLI]] Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene.<ref>PMID:8606168</ref> <ref>PMID:15485810</ref> <ref>PMID:19804784</ref>	+	[[https://www.uniprot.org/uniprot/PSPF_ECOLI PSPF_ECOLI]] Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene.<ref>PMID:8606168</ref> <ref>PMID:15485810</ref> <ref>PMID:19804784</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Transcriptional activator\|Transcriptional activator]]	+	*[[Transcriptional activator 3D structures\|Transcriptional activator 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:14, 26 February 2020

OCA — Wed, 26 Feb 2020 11:14:34 GMT

←Older revision		Revision as of 11:14, 26 February 2020
Line 1:		Line 1:

	==Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF==		==Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF==
-	<StructureSection load='2c99' size='340' side='right' caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2c99' size='340' side='right'caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C99 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C99 FirstGlance]. <br>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Buck, M]]		[[Category: Buck, M]]
	[[Category: Niwa, H]]		[[Category: Niwa, H]]

OCA at 08:46, 23 May 2018

OCA — Wed, 23 May 2018 08:46:24 GMT

←Older revision		Revision as of 08:46, 23 May 2018
Line 1:		Line 1:
		+
	==Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF==		==Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF==
	<StructureSection load='2c99' size='340' side='right' caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2c99' size='340' side='right' caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [http://pdbe.org/2c99 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [http://www.ebi.ac.uk/pdbsum/2c99 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [http://pdbe.org/2c99 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [http://www.ebi.ac.uk/pdbsum/2c99 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2c99 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/2c99_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/2c99_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:47, 8 February 2016

OCA — Mon, 08 Feb 2016 15:47:45 GMT

←Older revision		Revision as of 15:47, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c99 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:06, 10 September 2015

OCA — Thu, 10 Sep 2015 13:06:13 GMT

←Older revision		Revision as of 13:06, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2c99' size='340' side='right' caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2c99' size='340' side='right' caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C99 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C99 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [http://www.ebi.ac.uk/pdbsum/2c99 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [http://pdbe.org/2c99 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [http://www.ebi.ac.uk/pdbsum/2c99 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2c99" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Buck, M]]		[[Category: Buck, M]]
	[[Category: Niwa, H]]		[[Category: Niwa, H]]

OCA at 00:26, 25 December 2014

OCA — Thu, 25 Dec 2014 00:26:10 GMT

←Older revision		Revision as of 00:26, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C99 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C99 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [http://www.ebi.ac.uk/pdbsum/2c99 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [http://www.ebi.ac.uk/pdbsum/2c99 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PSPF_ECOLI PSPF_ECOLI]] Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene.<ref>PMID:8606168</ref> <ref>PMID:15485810</ref> <ref>PMID:19804784</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
-	[[Category: Buck, M.]]	+	[[Category: Buck, M]]
-	[[Category: Niwa, H.]]	+	[[Category: Niwa, H]]
-	[[Category: Rappas, M.]]	+	[[Category: Rappas, M]]
-	[[Category: Schumacher, J.]]	+	[[Category: Schumacher, J]]
-	[[Category: Zhang, X.]]	+	[[Category: Zhang, X]]
	[[Category: Atp-binding]]		[[Category: Atp-binding]]
	[[Category: Atpase]]		[[Category: Atpase]]

OCA at 03:05, 30 September 2014

OCA — Tue, 30 Sep 2014 03:05:58 GMT

←Older revision		Revision as of 03:05, 30 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2c99\| PDB=2c99 \| SCENE= }}~~	+	==Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF==
-	===Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF===	+	<StructureSection load='2c99' size='340' side='right' caption='[[2c99]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_16430918}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C99 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bjv\|2bjv]], [[2bjw\|2bjw]], [[2c96\|2c96]], [[2c98\|2c98]], [[2c9c\|2c9c]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c99 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c99 RCSB], [http://www.ebi.ac.uk/pdbsum/2c99 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/2c99_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial enhancer-binding proteins (EBP) activate transcription by hydrolyzing ATP to restructure the sigma(54)-RNA polymerase-promoter complex. We compare six high resolution structures (<2.1 A) of the AAA(+) domain of EBP phage shock protein F (PspF) including apo, AMPPNP, Mg(2+)-ATP, and ADP forms. These structures permit a description of the atomic details underpinning the origins of the conformational changes occurring during ATP hydrolysis. Conserved regions of PspF's AAA(+) domain respond distinctively to nucleotide binding and hydrolysis, suggesting functional roles during the hydrolysis cycle, which completely agree with those derived from activities of PspF mutated at these positions. We propose a putative atomic switch that is responsible for coupling structural changes in the nucleotide-binding site to the repositioning of the sigma(54)-interacting loops. Striking similarities in nucleotide-specific conformational changes and atomic switch exist between PspF and the large T antigen helicase, suggesting conservation in the origin of those events amongst AAA(+) proteins.

-	~~==Function==~~	+	Structural basis of the nucleotide driven conformational changes in the AAA+ domain of transcription activator PspF.,Rappas M, Schumacher J, Niwa H, Buck M, Zhang X J Mol Biol. 2006 Mar 24;357(2):481-92. Epub 2006 Jan 13. PMID:16430918<ref>PMID:16430918</ref>
-	~~[[http://www~~.~~uniprot~~.~~org/uniprot/PSPF_ECOLI PSPF_ECOLI]] Transcriptional activator for the phage shock protein~~ (~~psp~~) ~~operon (pspABCDE) and pspG gene~~.~~<ref>~~PMID:~~8606168</ref><ref>PMID:15485810</ref>~~<ref>PMID:~~19804784~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[2c99]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:016430918</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[Transcriptional activator\|Transcriptional activator]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
	[[Category: Buck, M.]]		[[Category: Buck, M.]]

OCA at 07:50, 27 March 2013

OCA — Wed, 27 Mar 2013 07:50:59 GMT

←Older revision		Revision as of 07:50, 27 March 2013
Line 1:		Line 1:
-	[[Image:2c99.png\|left\|200px]]
-
	{{STRUCTURE_2c99\| PDB=2c99 \| SCENE= }}		{{STRUCTURE_2c99\| PDB=2c99 \| SCENE= }}
		+	===Structural basis of the nucleotide driven conformational changes in the AAA domain of transcription activator PspF===
		+	{{ABSTRACT_PUBMED_16430918}}

-	===~~STRUCTURAL BASIS OF THE NUCLEOTIDE DRIVEN CONFORMATIONAL CHANGES IN THE AAA DOMAIN OF TRANSCRIPTION ACTIVATOR PSPF~~===	+	==Function==
-		+	[[http://www.uniprot.org/uniprot/PSPF_ECOLI PSPF_ECOLI]] Transcriptional activator for the phage shock protein (psp) operon (pspABCDE) and pspG gene.<ref>PMID:8606168</ref><ref>PMID:15485810</ref><ref>PMID:19804784</ref>
-	~~{{ABSTRACT_PUBMED_16430918}}~~	+

	==About this Structure==		==About this Structure==
-	[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli~~ Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA].	+	[[2c99]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C99 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:016430918</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016430918</ref><references group="xtra"/><references/>
-	[[Category: Escherichia coli]]	+	[[Category: Escherichia coli k-12]]
	[[Category: Buck, M.]]		[[Category: Buck, M.]]
	[[Category: Niwa, H.]]		[[Category: Niwa, H.]]

OCA: Protected "2c99" [edit=sysop:move=sysop]

OCA — Sun, 06 Jan 2013 12:15:28 GMT

Protected "2c99" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:15, 6 January 2013