2cfq - Revision history

OCA at 14:16, 13 December 2023

OCA — Wed, 13 Dec 2023 14:16:09 GMT

←Older revision		Revision as of 14:16, 13 December 2023
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	<StructureSection load='2cfq' size='340' side='right'caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='2cfq' size='340' side='right'caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.95Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [https://pdbe.org/2cfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [https://www.ebi.ac.uk/pdbsum/2cfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [https://pdbe.org/2cfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [https://www.ebi.ac.uk/pdbsum/2cfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LACY_ECOLI LACY_ECOLI]] Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system).	+	[https://www.uniprot.org/uniprot/LACY_ECOLI LACY_ECOLI] Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Guan, L]]	+	[[Category: Guan L]]
-	[[Category: Iwata, S]]	+	[[Category: Iwata S]]
-	[[Category: Kaback~~, H R~~]]	+	[[Category: Kaback HR]]
-	[[Category: Mirza, O]]	+	[[Category: Mirza O]]
-	[[Category: Verner, G]]	+	[[Category: Verner G]]
-	~~[[Category: Formylation]]~~	+
-	~~[[Category: Lactose permease]]~~	+
-	~~[[Category: Lactose/h+ symport]]~~	+
-	~~[[Category: Sugar transport]]~~	+
-	~~[[Category: Transmembrane]]~~	+
-	~~[[Category: Transport]]~~	+
-	~~[[Category: Transport mechanism~~]]	+

OCA at 06:54, 1 December 2021

OCA — Wed, 01 Dec 2021 06:54:41 GMT

←Older revision		Revision as of 06:54, 1 December 2021
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	<StructureSection load='2cfq' size='340' side='right'caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='2cfq' size='340' side='right'caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [~~http~~://pdbe.org/2cfq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2cfq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [https://pdbe.org/2cfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [https://www.ebi.ac.uk/pdbsum/2cfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LACY_ECOLI LACY_ECOLI]] Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system).	+	[[https://www.uniprot.org/uniprot/LACY_ECOLI LACY_ECOLI]] Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[Lactose Permease\|Lactose Permease]]		*[[Lactose Permease\|Lactose Permease]]
-	*[[Major Facilitators\|Major Facilitators]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:42, 26 February 2020

OCA — Wed, 26 Feb 2020 10:42:43 GMT

←Older revision		Revision as of 10:42, 26 February 2020
Line 1:		Line 1:

	==Sugar Free Lactose Permease at neutral pH==		==Sugar Free Lactose Permease at neutral pH==
-	<StructureSection load='2cfq' size='340' side='right' caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>	+	<StructureSection load='2cfq' size='340' side='right'caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Guan, L]]		[[Category: Guan, L]]
	[[Category: Iwata, S]]		[[Category: Iwata, S]]

OCA at 07:56, 23 May 2018

OCA — Wed, 23 May 2018 07:56:17 GMT

←Older revision		Revision as of 07:56, 23 May 2018
Line 1:		Line 1:
-	==~~SUGAR FREE LACTOSE PERMEASE AT NEUTRAL PH~~==	+
		+	==Sugar Free Lactose Permease at neutral pH==
	<StructureSection load='2cfq' size='340' side='right' caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='2cfq' size='340' side='right' caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [http://pdbe.org/2cfq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [http://www.ebi.ac.uk/pdbsum/2cfq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [http://pdbe.org/2cfq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [http://www.ebi.ac.uk/pdbsum/2cfq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cfq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:02, 9 February 2016

OCA — Tue, 09 Feb 2016 02:02:10 GMT

←Older revision		Revision as of 02:02, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cfq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:31, 10 September 2015

OCA — Thu, 10 Sep 2015 17:31:47 GMT

←Older revision		Revision as of 17:31, 10 September 2015
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	<StructureSection load='2cfq' size='340' side='right' caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='2cfq' size='340' side='right' caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [http://www.ebi.ac.uk/pdbsum/2cfq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [http://pdbe.org/2cfq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [http://www.ebi.ac.uk/pdbsum/2cfq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2cfq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Guan, L]]		[[Category: Guan, L]]
	[[Category: Iwata, S]]		[[Category: Iwata, S]]

OCA at 03:39, 25 December 2014

OCA — Thu, 25 Dec 2014 03:39:36 GMT

←Older revision		Revision as of 03:39, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [http://www.ebi.ac.uk/pdbsum/2cfq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [http://www.ebi.ac.uk/pdbsum/2cfq PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LACY_ECOLI LACY_ECOLI]] Responsible for transport of beta-galactosides into the cell, with the concomitant import of a proton (symport system).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Guan, L.]]	+	[[Category: Guan, L]]
-	[[Category: Iwata, S.]]	+	[[Category: Iwata, S]]
-	[[Category: Kaback, H R.]]	+	[[Category: Kaback, H R]]
-	[[Category: Mirza, O.]]	+	[[Category: Mirza, O]]
-	[[Category: Verner, G.]]	+	[[Category: Verner, G]]
	[[Category: Formylation]]		[[Category: Formylation]]
	[[Category: Lactose permease]]		[[Category: Lactose permease]]

OCA at 01:29, 30 September 2014

OCA — Tue, 30 Sep 2014 01:29:32 GMT

←Older revision		Revision as of 01:29, 30 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2cfq\| PDB=2cfq \| SCENE= }}~~	+	==SUGAR FREE LACTOSE PERMEASE AT NEUTRAL PH==
-	===SUGAR FREE LACTOSE PERMEASE AT NEUTRAL PH===	+	<StructureSection load='2cfq' size='340' side='right' caption='[[2cfq]], [[Resolution\|resolution]] 2.95Å' scene=''>
-	~~{{ABSTRACT_PUBMED_16525509}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1m2u\|1m2u]], [[1pv6\|1pv6]], [[1pv7\|1pv7]], [[2cfp\|2cfp]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cfq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cfq RCSB], [http://www.ebi.ac.uk/pdbsum/2cfq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cfq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cation-coupled active transport is an essential cellular process found ubiquitously in all living organisms. Here, we present two novel ligand-free X-ray structures of the lactose permease (LacY) of Escherichia coli determined at acidic and neutral pH, and propose a model for the mechanism of coupling between lactose and H+ translocation. No sugar-binding site is observed in the absence of ligand, and deprotonation of the key residue Glu269 is associated with ligand binding. Thus, substrate induces formation of the sugar-binding site, as well as the initial step in H+ transduction.

-	~~==About this Structure==~~	+	Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY.,Mirza O, Guan L, Verner G, Iwata S, Kaback HR EMBO J. 2006 Mar 22;25(6):1177-83. Epub 2006 Mar 9. PMID:16525509<ref>PMID:16525509</ref>
-	~~[[2cfq]] is~~ a ~~1 chain structure with sequence from [http:~~/~~/en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2CFQ OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Lactose Permease\|Lactose Permease]]		*[[Lactose Permease\|Lactose Permease]]
	*[[Major Facilitators\|Major Facilitators]]		*[[Major Facilitators\|Major Facilitators]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016525509<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Guan, L.]]		[[Category: Guan, L.]]

OCA at 10:13, 11 March 2013

OCA — Mon, 11 Mar 2013 10:13:00 GMT

←Older revision		Revision as of 10:13, 11 March 2013
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-	[[Image:2cfq.png\|left\|200px]]
-
	{{STRUCTURE_2cfq\| PDB=2cfq \| SCENE= }}		{{STRUCTURE_2cfq\| PDB=2cfq \| SCENE= }}
-
	===SUGAR FREE LACTOSE PERMEASE AT NEUTRAL PH===		===SUGAR FREE LACTOSE PERMEASE AT NEUTRAL PH===
-
	{{ABSTRACT_PUBMED_16525509}}		{{ABSTRACT_PUBMED_16525509}}

OCA at 12:16, 20 October 2012

OCA — Sat, 20 Oct 2012 12:16:04 GMT

←Older revision		Revision as of 12:16, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2cfq]] is a 1 chain structure ~~of [[Lactose Permease]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA].	+	[[2cfq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFQ OCA].

	==See Also==		==See Also==