2chd - Revision history

OCA at 14:17, 13 December 2023

OCA — Wed, 13 Dec 2023 14:17:11 GMT

←Older revision		Revision as of 14:17, 13 December 2023
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	<StructureSection load='2chd' size='340' side='right'caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>		<StructureSection load='2chd' size='340' side='right'caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHD FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.92Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1zbd\|1zbd]], [[3rpb\|3rpb]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [https://pdbe.org/2chd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [https://www.ebi.ac.uk/pdbsum/2chd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [https://pdbe.org/2chd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [https://www.ebi.ac.uk/pdbsum/2chd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chd ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Buffalo rat]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Becker, S~~]]	+	[[Category: Rattus norvegicus]]
-	[[Category: ~~Biadene, M~~]]	+	[[Category: Becker S]]
-	[[Category: ~~Montaville, P]]~~	+	[[Category: Biadene M]]
-	~~[[Category: Sheldrick, G~~ M]]	+	[[Category: Montaville P]]
-	[[Category: ~~C2 domain~~]]	+	[[Category: Sheldrick GM]]
-	[[Category: ~~C2a]]~~	+
-	~~[[Category: Calcium binding]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Rabphilin-3a]]~~	+
-	~~[[Category: Synapse]]~~	+
-	~~[[Category: Synaptic exocytosis]]~~	+
-	~~[[Category: Transport]]~~	+
-	~~[[Category: Zinc-finger~~]]	+

OCA at 12:11, 27 April 2022

OCA — Wed, 27 Apr 2022 12:11:43 GMT

←Older revision		Revision as of 12:11, 27 April 2022
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	<StructureSection load='2chd' size='340' side='right'caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>		<StructureSection load='2chd' size='340' side='right'caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2CHD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CHD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zbd\|1zbd]], [[3rpb\|3rpb]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [~~http~~://pdbe.org/2chd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2chd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2chd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [https://pdbe.org/2chd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [https://www.ebi.ac.uk/pdbsum/2chd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2chd ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
	*[[Exophilin 3D structures\|Exophilin 3D structures]]		*[[Exophilin 3D structures\|Exophilin 3D structures]]
		+	*[[Rabphilin\|Rabphilin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:09, 22 July 2020

OCA — Wed, 22 Jul 2020 12:09:28 GMT

←Older revision		Revision as of 12:09, 22 July 2020
Line 1:		Line 1:

	==Crystal structure of the C2A domain of Rabphilin-3A==		==Crystal structure of the C2A domain of Rabphilin-3A==
-	<StructureSection load='2chd' size='340' side='right' caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>	+	<StructureSection load='2chd' size='340' side='right'caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2CHD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2CHD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://pdbe.org/2chd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2chd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://pdbe.org/2chd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2chd ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 2chd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2chd" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Exophilin 3D structures\|Exophilin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Buffalo rat]]		[[Category: Buffalo rat]]
		+	[[Category: Large Structures]]
	[[Category: Becker, S]]		[[Category: Becker, S]]
	[[Category: Biadene, M]]		[[Category: Biadene, M]]

OCA at 07:57, 23 May 2018

OCA — Wed, 23 May 2018 07:57:18 GMT

←Older revision		Revision as of 07:57, 23 May 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF THE~~ C2A ~~DOMAIN OF RABPHILIN~~-3A==	+
		+	==Crystal structure of the C2A domain of Rabphilin-3A==
	<StructureSection load='2chd' size='340' side='right' caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>		<StructureSection load='2chd' size='340' side='right' caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://pdbe.org/2chd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://pdbe.org/2chd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2chd ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2chd_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2chd_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:30, 9 February 2016

OCA — Tue, 09 Feb 2016 21:30:42 GMT

←Older revision		Revision as of 21:30, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2chd ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:13, 11 September 2015

OCA — Fri, 11 Sep 2015 02:13:50 GMT

←Older revision		Revision as of 02:13, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2chd' size='340' side='right' caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>		<StructureSection load='2chd' size='340' side='right' caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rattus_norvegicus Rattus norvegicus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://pdbe.org/2chd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2chd" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Rattus norvegicus~~]]	+	[[Category: Buffalo rat]]
	[[Category: Becker, S]]		[[Category: Becker, S]]
	[[Category: Biadene, M]]		[[Category: Biadene, M]]

OCA at 17:23, 15 January 2015

OCA — Thu, 15 Jan 2015 17:23:44 GMT

←Older revision		Revision as of 17:23, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHD FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Becker, S.]]	+	[[Category: Becker, S]]
-	[[Category: Biadene, M.]]	+	[[Category: Biadene, M]]
-	[[Category: Montaville, P.]]	+	[[Category: Montaville, P]]
-	[[Category: Sheldrick, G M.]]	+	[[Category: Sheldrick, G M]]
	[[Category: C2 domain]]		[[Category: C2 domain]]
	[[Category: C2a]]		[[Category: C2a]]

OCA at 00:39, 30 September 2014

OCA — Tue, 30 Sep 2014 00:39:40 GMT

←Older revision		Revision as of 00:39, 30 September 2014
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-	[[~~Image:~~2chd.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THE C2A DOMAIN OF RABPHILIN-3A==
		+	<StructureSection load='2chd' size='340' side='right' caption='[[2chd]], [[Resolution\|resolution]] 1.92Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CHD FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zbd\|1zbd]], [[3rpb\|3rpb]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2chd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2chd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2chd RCSB], [http://www.ebi.ac.uk/pdbsum/2chd PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ch/2chd_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rabphilin-3A is a neuronal protein containing a C2-domain tandem. To date, only the structure of the C2B domain has been solved. The crystal structure of the Ca2+-free C2A domain has been solved by molecular replacement and refined to 1.92 A resolution. It adopts the classical C2-domain fold consisting of an eight-stranded antiparallel beta-sandwich with type I topology. In agreement with its Ca2+-dependent negatively charged membrane-binding properties, this C2 domain contains all the conserved acidic residues responsible for calcium binding. However, the replacement of a conserved aspartic acid residue by glutamic acid allows formation of an additional strong hydrogen bond, resulting in increased rigidity of calcium-binding loop 1. The electrostatic surface of the C2A domain consists of a large positively charged belt surrounded by two negatively charged patches located at both tips of the domain. In comparison, the structurally very similar C2A domain of synaptotagmin I has a highly acidic electrostatic surface, suggesting completely unrelated functions for these two C2A domains.

-	~~{{STRUCTURE_2chd\| PDB=2chd \| SCENE= }}~~	+	Structure of the C2A domain of rabphilin-3A.,Biadene M, Montaville P, Sheldrick GM, Becker S Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):793-9. Epub 2006, Jun 20. PMID:16790935<ref>PMID:16790935</ref>

-	~~===CRYSTAL STRUCTURE OF THE C2A DOMAIN OF RABPHILIN-3A===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16790935}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2chd]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rattus_norvegicus Rattus norvegicus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016790935<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Becker, S.]]		[[Category: Becker, S.]]

OCA: Protected "2chd" [edit=sysop:move=sysop]

OCA — Sun, 06 Jan 2013 10:01:27 GMT

Protected "2chd" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:01, 6 January 2013

OCA at 10:01, 6 January 2013

OCA — Sun, 06 Jan 2013 10:01:24 GMT

←Older revision		Revision as of 10:01, 6 January 2013
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-	{{Seed}}
	[[Image:2chd.png\|left\|200px]]		[[Image:2chd.png\|left\|200px]]

-	<!--
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-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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	{{STRUCTURE_2chd\| PDB=2chd \| SCENE= }}		{{STRUCTURE_2chd\| PDB=2chd \| SCENE= }}

	===CRYSTAL STRUCTURE OF THE C2A DOMAIN OF RABPHILIN-3A===		===CRYSTAL STRUCTURE OF THE C2A DOMAIN OF RABPHILIN-3A===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16790935}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16790935 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16790935}}		{{ABSTRACT_PUBMED_16790935}}

	==About this Structure==		==About this Structure==
-	~~2CHD~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA].	+	[[2chd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHD OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16790935~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016790935</ref><references group="xtra"/>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Becker, S.]]		[[Category: Becker, S.]]
Line 38:		Line 26:
	[[Category: Synaptic exocytosis]]		[[Category: Synaptic exocytosis]]
	[[Category: Transport]]		[[Category: Transport]]
-	[[Category: Zinc]]
	[[Category: Zinc-finger]]		[[Category: Zinc-finger]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:53:53 2009''