2d3v - Revision history

OCA at 11:34, 22 May 2024

OCA — Wed, 22 May 2024 11:34:03 GMT

←Older revision		Revision as of 11:34, 22 May 2024
Line 3:		Line 3:
	<StructureSection load='2d3v' size='340' side='right'caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2d3v' size='340' side='right'caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D3V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D3V FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non~~-~~Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [https://pdbe.org/2d3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [https://www.ebi.ac.uk/pdbsum/2d3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [https://pdbe.org/2d3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [https://www.ebi.ac.uk/pdbsum/2d3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3v ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/LIRA5_HUMAN LIRA5_HUMAN] May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition.<ref>PMID:16675463</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kajikawa, M]]	+	[[Category: Kajikawa M]]
-	[[Category: Kohda, D]]	+	[[Category: Kohda D]]
-	[[Category: Kuroki, K]]	+	[[Category: Kuroki K]]
-	[[Category: Maenaka, K]]	+	[[Category: Maenaka K]]
-	[[Category: Ose, T]]	+	[[Category: Ose T]]
-	[[Category: Shiroishi, M]]	+	[[Category: Shiroishi M]]
-	~~[[Category: Immune system]]~~	+
-	~~[[Category: Immunoglobulin-like fold~~]]	+

OCA at 10:27, 8 December 2021

OCA — Wed, 08 Dec 2021 10:27:06 GMT

←Older revision		Revision as of 10:27, 8 December 2021
Line 3:		Line 3:
	<StructureSection load='2d3v' size='340' side='right'caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2d3v' size='340' side='right'caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2D3V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D3V FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [~~http~~://pdbe.org/2d3v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2d3v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3v ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [https://pdbe.org/2d3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [https://www.ebi.ac.uk/pdbsum/2d3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3v ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 2d3v" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2d3v" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Leukocyte immunoglobulin-like receptor\|Leukocyte immunoglobulin-like receptor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:45, 4 March 2020

OCA — Wed, 04 Mar 2020 07:45:28 GMT

←Older revision		Revision as of 07:45, 4 March 2020
Line 1:		Line 1:

	==Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)==		==Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)==
-	<StructureSection load='2d3v' size='340' side='right' caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='2d3v' size='340' side='right'caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Kajikawa, M]]		[[Category: Kajikawa, M]]
	[[Category: Kohda, D]]		[[Category: Kohda, D]]

OCA at 06:31, 30 May 2018

OCA — Wed, 30 May 2018 06:31:07 GMT

←Older revision		Revision as of 06:31, 30 May 2018
Line 1:		Line 1:
		+
	==Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)==		==Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)==
	<StructureSection load='2d3v' size='340' side='right' caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2d3v' size='340' side='right' caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [http://pdbe.org/2d3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [http://www.ebi.ac.uk/pdbsum/2d3v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [http://pdbe.org/2d3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [http://www.ebi.ac.uk/pdbsum/2d3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3v ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3v_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3v_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 04:50, 10 February 2016

OCA — Wed, 10 Feb 2016 04:50:43 GMT

←Older revision		Revision as of 04:50, 10 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d3v ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:33, 11 September 2015

OCA — Fri, 11 Sep 2015 05:33:02 GMT

←Older revision		Revision as of 05:33, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2d3v' size='340' side='right' caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2d3v' size='340' side='right' caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [http://www.ebi.ac.uk/pdbsum/2d3v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [http://pdbe.org/2d3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [http://www.ebi.ac.uk/pdbsum/2d3v PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2d3v" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Kajikawa, M]]		[[Category: Kajikawa, M]]
	[[Category: Kohda, D]]		[[Category: Kohda, D]]

OCA at 18:03, 15 January 2015

OCA — Thu, 15 Jan 2015 18:03:10 GMT

←Older revision		Revision as of 18:03, 15 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>		<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [http://www.ebi.ac.uk/pdbsum/2d3v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [http://www.ebi.ac.uk/pdbsum/2d3v PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Kajikawa, M.]]	+	[[Category: Kajikawa, M]]
-	[[Category: Kohda, D.]]	+	[[Category: Kohda, D]]
-	[[Category: Kuroki, K.]]	+	[[Category: Kuroki, K]]
-	[[Category: Maenaka, K.]]	+	[[Category: Maenaka, K]]
-	[[Category: Ose, T.]]	+	[[Category: Ose, T]]
-	[[Category: Shiroishi, M.]]	+	[[Category: Shiroishi, M]]
	[[Category: Immune system]]		[[Category: Immune system]]
	[[Category: Immunoglobulin-like fold]]		[[Category: Immunoglobulin-like fold]]

OCA at 01:04, 30 September 2014

OCA — Tue, 30 Sep 2014 01:04:15 GMT

←Older revision		Revision as of 01:04, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2d3v.~~png\|left~~\|200px]]	+	==Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)==
		+	<StructureSection load='2d3v' size='340' side='right' caption='[[2d3v]], [[Resolution\|resolution]] 1.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3V FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2d3v RCSB], [http://www.ebi.ac.uk/pdbsum/2d3v PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3v_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Human leukocyte Ig-like receptor B1 (LILRB1) and B2 (LILRB2) belong to "Group 1" receptors and recognize a broad range of major histocompatibility complex class I molecules (MHCIs). In contrast, "Group 2" receptors show low similarity with LILRB1/B2, and their ligands remain to be identified. To date, the structural and functional characteristics of Group 2 LILRs are poorly understood. Here we report the crystal structure of the extracellular domain of LILRA5, which is an activating Group 2 LILR expressed on monocytes and neutrophils. Unexpectedly, the structure showed large changes in structural conformation and charge distribution in the region corresponding to the MHCI binding site of LILRB1/B2, which are also distinct from killer cell Ig-like receptors and Fc alpha receptors. These changes probably confer the structural hindrance for the MHCI binding, and their key amino acid substitutions are well conserved in Group 2 LILRs. Consistently, the surface plasmon resonance and flow cytometric analyses demonstrated that LILRA5 exhibited no affinities to all tested MHCIs. These results raised the possibility that LILRA5 as well as Group 2 LILRs do not play a role in any MHCI recognition but could possibly bind to non-MHCI ligand(s) on the target cells to provide a novel immune regulation mechanism.

-	~~{{STRUCTURE_2d3v\| PDB=2d3v \| SCENE= }}~~	+	Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11).,Shiroishi M, Kajikawa M, Kuroki K, Ose T, Kohda D, Maenaka K J Biol Chem. 2006 Jul 14;281(28):19536-44. Epub 2006 May 3. PMID:16675463<ref>PMID:16675463</ref>

-	~~===Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5~~/~~LIR9/ILT11)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16675463}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2d3v]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016675463<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Kajikawa, M.]]		[[Category: Kajikawa, M.]]

OCA: Protected "2d3v" [edit=sysop:move=sysop]

OCA — Sun, 06 Jan 2013 10:21:02 GMT

Protected "2d3v" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:21, 6 January 2013

OCA at 10:20, 6 January 2013

OCA — Sun, 06 Jan 2013 10:20:58 GMT

←Older revision		Revision as of 10:20, 6 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2d3v.png\|left\|200px]]		[[Image:2d3v.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2d3v", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2d3v\| PDB=2d3v \| SCENE= }}		{{STRUCTURE_2d3v\| PDB=2d3v \| SCENE= }}

	===Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)===		===Crystal Structure of Leukocyte Ig-like Receptor A5 (LILRA5/LIR9/ILT11)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16675463}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16675463 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16675463}}		{{ABSTRACT_PUBMED_16675463}}

	==About this Structure==		==About this Structure==
-	~~2D3V~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA].	+	[[2d3v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3V OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16675463~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016675463</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Kajikawa, M.]]		[[Category: Kajikawa, M.]]
Line 31:		Line 19:
	[[Category: Ose, T.]]		[[Category: Ose, T.]]
	[[Category: Shiroishi, M.]]		[[Category: Shiroishi, M.]]
		+	[[Category: Immune system]]
	[[Category: Immunoglobulin-like fold]]		[[Category: Immunoglobulin-like fold]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:34:10 2009''