2dkt - Revision history

OCA at 18:42, 29 May 2024

OCA — Wed, 29 May 2024 18:42:54 GMT

←Older revision		Revision as of 18:42, 29 May 2024
Line 1:		Line 1:

	==Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus==		==Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus==
-	<StructureSection load='2dkt' size='340' side='right'caption='[[2dkt~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2dkt' size='340' side='right'caption='[[2dkt]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DKT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DKT FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~Rchy1 ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [https://pdbe.org/2dkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [https://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dkt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [https://pdbe.org/2dkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [https://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dkt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ZN363_MOUSE ZN363_MOUSE]] Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Increases AR transcription factor activity. Monoubiquitinates the translesion DNA polymerase POLH (By similarity). Contributes to the regulation of the cell cycle progression.	+	[https://www.uniprot.org/uniprot/ZN363_MOUSE ZN363_MOUSE] Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Increases AR transcription factor activity. Monoubiquitinates the translesion DNA polymerase POLH (By similarity). Contributes to the regulation of the cell cycle progression.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Inoue, M]]	+	[[Category: Inoue M]]
-	[[Category: Kigawa, T]]	+	[[Category: Kigawa T]]
-	[[Category: Koshiba, S]]	+	[[Category: Koshiba S]]
-	[[Category: Miyamoto, K]]	+	[[Category: Miyamoto K]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Yokoyama S]]
-	[[Category: Yokoyama, S]]	+
-	~~[[Category: Chy zinc finger domain]]~~	+
-	~~[[Category: Metal binding protein]]~~	+
-	~~[[Category: National project on protein structural and functional analyse]]~~	+
-	~~[[Category: Nppsfa]]~~	+
-	~~[[Category: Rchy1]]~~	+
-	~~[[Category: Ring finger and chy zinc finger domain-containing protein 1]]~~	+
-	~~[[Category: Rsgi~~]]	+

OCA at 12:05, 3 February 2021

OCA — Wed, 03 Feb 2021 12:05:59 GMT

←Older revision		Revision as of 12:05, 3 February 2021
Line 1:		Line 1:

	==Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus==		==Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus==
-	<StructureSection load='2dkt' size='340' side='right' caption='[[2dkt]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2dkt' size='340' side='right'caption='[[2dkt]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DKT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DKT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [~~http~~://pdbe.org/2dkt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2dkt ProSAT], [~~http~~://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [https://pdbe.org/2dkt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [https://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dkt ProSAT], [https://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ZN363_MOUSE ZN363_MOUSE]] Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Increases AR transcription factor activity. Monoubiquitinates the translesion DNA polymerase POLH (By similarity). Contributes to the regulation of the cell cycle progression.	+	[[https://www.uniprot.org/uniprot/ZN363_MOUSE ZN363_MOUSE]] Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Increases AR transcription factor activity. Monoubiquitinates the translesion DNA polymerase POLH (By similarity). Contributes to the regulation of the cell cycle progression.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Inoue, M]]		[[Category: Inoue, M]]

OCA at 06:09, 30 May 2018

OCA — Wed, 30 May 2018 06:09:48 GMT

←Older revision		Revision as of 06:09, 30 May 2018
Line 1:		Line 1:
		+
	==Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus==		==Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus==
	<StructureSection load='2dkt' size='340' side='right' caption='[[2dkt]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2dkt' size='340' side='right' caption='[[2dkt]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [http://pdbe.org/2dkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [http://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [http://pdbe.org/2dkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [http://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dkt ProSAT], [http://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dkt_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dkt_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dkt ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 16:31, 11 September 2015

OCA — Fri, 11 Sep 2015 16:31:51 GMT

←Older revision		Revision as of 16:31, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2dkt' size='340' side='right' caption='[[2dkt]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2dkt' size='340' side='right' caption='[[2dkt]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [http://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [http://pdbe.org/2dkt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [http://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Inoue, M]]		[[Category: Inoue, M]]
	[[Category: Kigawa, T]]		[[Category: Kigawa, T]]

OCA at 19:02, 25 December 2014

OCA — Thu, 25 Dec 2014 19:02:48 GMT

←Older revision		Revision as of 19:02, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKT FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [http://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [http://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ZN363_MOUSE ZN363_MOUSE]] Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Increases AR transcription factor activity. Monoubiquitinates the translesion DNA polymerase POLH (By similarity). Contributes to the regulation of the cell cycle progression.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 20:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Inoue, M.]]	+	[[Category: Inoue, M]]
-	[[Category: Kigawa, T.]]	+	[[Category: Kigawa, T]]
-	[[Category: Koshiba, S.]]	+	[[Category: Koshiba, S]]
-	[[Category: Miyamoto, K.]]	+	[[Category: Miyamoto, K]]
-	[[Category: ~~RSGI, RIKEN~~ Structural ~~Genomics/Proteomics Initiative.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Yokoyama, S.]]	+	[[Category: Yokoyama, S]]
	[[Category: Chy zinc finger domain]]		[[Category: Chy zinc finger domain]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
Line 31:		Line 33:
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
	[[Category: Rchy1]]		[[Category: Rchy1]]
-	[[Category: Riken structural genomics/proteomics initiative]]
	[[Category: Ring finger and chy zinc finger domain-containing protein 1]]		[[Category: Ring finger and chy zinc finger domain-containing protein 1]]
	[[Category: Rsgi]]		[[Category: Rsgi]]
-	[[Category: Structural genomic]]

OCA at 23:46, 29 September 2014

OCA — Mon, 29 Sep 2014 23:46:29 GMT

←Older revision		Revision as of 23:46, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:2dkt.png\|left\|200px]]~~	+	==Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus==
-		+	<StructureSection load='2dkt' size='340' side='right' caption='[[2dkt]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~{{STRUCTURE_2dkt\| PDB=2dkt \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2dkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DKT FirstGlance]. <br>
-	===Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Rchy1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dkt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dkt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dkt RCSB], [http://www.ebi.ac.uk/pdbsum/2dkt PDBsum], [http://www.topsan.org/Proteins/RSGI/2dkt TOPSAN]</span></td></tr>
-	==~~About this Structure~~==	+	<table>
-	[[2dkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA].	+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/2dkt_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Inoue, M.]]		[[Category: Inoue, M.]]

OCA: Protected "2dkt" [edit=sysop:move=sysop]

OCA — Sun, 06 Jan 2013 09:16:29 GMT

Protected "2dkt" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:16, 6 January 2013

OCA at 09:16, 6 January 2013

OCA — Sun, 06 Jan 2013 09:16:25 GMT

←Older revision		Revision as of 09:16, 6 January 2013
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-	{{Seed}}
	[[Image:2dkt.png\|left\|200px]]		[[Image:2dkt.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2dkt", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_2dkt\| PDB=2dkt \| SCENE= }}		{{STRUCTURE_2dkt\| PDB=2dkt \| SCENE= }}

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	==About this Structure==		==About this Structure==
-	~~2DKT~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA].	+	[[2dkt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA].
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Inoue, M.]]		[[Category: Inoue, M.]]
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	[[Category: Yokoyama, S.]]		[[Category: Yokoyama, S.]]
	[[Category: Chy zinc finger domain]]		[[Category: Chy zinc finger domain]]
		+	[[Category: Metal binding protein]]
	[[Category: National project on protein structural and functional analyse]]		[[Category: National project on protein structural and functional analyse]]
	[[Category: Nppsfa]]		[[Category: Nppsfa]]
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	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 09:44:02 2008''

OCA at 07:44, 16 November 2008

OCA — Sun, 16 Nov 2008 07:44:03 GMT

←Older revision		Revision as of 07:44, 16 November 2008
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	==About this Structure==		==About this Structure==
-	2DKT is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA].	+	2DKT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA].
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Single protein]]
	[[Category: Inoue, M.]]		[[Category: Inoue, M.]]
	[[Category: Kigawa, T.]]		[[Category: Kigawa, T.]]
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	[[Category: Structural genomic]]		[[Category: Structural genomic]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~Sep 28 14~~:55:28 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 09:44:02 2008''

OCA at 11:55, 28 September 2008

OCA — Sun, 28 Sep 2008 11:55:30 GMT

←Older revision		Revision as of 11:55, 28 September 2008
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-	[[Image:2dkt.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2dkt.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2dkt\| PDB=2dkt \| SCENE= }}		{{STRUCTURE_2dkt\| PDB=2dkt \| SCENE= }}

-	~~'''~~Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus~~'''~~	+	===Solution structure of the CHY zinc finger domain of the RING finger and CHY zinc finger domain-containing protein 1 from Mus musculus===


	==About this Structure==		==About this Structure==
-	2DKT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA].	+	2DKT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DKT OCA].
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Single protein]]		[[Category: Single protein]]
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	[[Category: Rsgi]]		[[Category: Rsgi]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~May 4 00~~:38:02 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Sep 28 14:55:28 2008''