2drx - Revision history

OCA at 18:43, 20 September 2023

OCA — Wed, 20 Sep 2023 18:43:29 GMT

←Older revision		Revision as of 18:43, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DRX FirstGlance]. <br>		<table><tr><td colspan='2'>[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DRX FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=HYP:~~4~~-HYDROXYPROLINE'>HYP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2drt\|2drt]], [[1v4f\|1v4f]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [https://pdbe.org/2drx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [https://www.ebi.ac.uk/pdbsum/2drx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2drx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [https://pdbe.org/2drx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [https://www.ebi.ac.uk/pdbsum/2drx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2drx ProSAT]</span></td></tr>
	</table>		</table>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Okuyama, K]]	+	[[Category: Okuyama K]]
-	~~[[Category: Collagen]]~~	+
-	~~[[Category: Leu]]~~	+
-	~~[[Category: Structural protein]]~~	+
-	~~[[Category: Triple helix~~]]	+

OCA at 10:35, 8 December 2021

OCA — Wed, 08 Dec 2021 10:35:13 GMT

←Older revision		Revision as of 10:35, 8 December 2021
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	<StructureSection load='2drx' size='340' side='right'caption='[[2drx]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2drx' size='340' side='right'caption='[[2drx]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2DRX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DRX FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2drt\|2drt]], [[1v4f\|1v4f]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2drt\|2drt]], [[1v4f\|1v4f]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [~~http~~://pdbe.org/2drx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2drx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2drx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [https://pdbe.org/2drx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [https://www.ebi.ac.uk/pdbsum/2drx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2drx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:55, 4 March 2020

OCA — Wed, 04 Mar 2020 07:55:05 GMT

←Older revision		Revision as of 07:55, 4 March 2020
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	==Structure Analysis of (POG)4-(LOG)2-(POG)4==		==Structure Analysis of (POG)4-(LOG)2-(POG)4==
-	<StructureSection load='2drx' size='340' side='right' caption='[[2drx]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='2drx' size='340' side='right'caption='[[2drx]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DRX FirstGlance]. <br>		<table><tr><td colspan='2'>[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DRX FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Okuyama, K]]		[[Category: Okuyama, K]]
	[[Category: Collagen]]		[[Category: Collagen]]

OCA at 06:47, 30 May 2018

OCA — Wed, 30 May 2018 06:47:11 GMT

←Older revision		Revision as of 06:47, 30 May 2018
Line 1:		Line 1:
		+
	==Structure Analysis of (POG)4-(LOG)2-(POG)4==		==Structure Analysis of (POG)4-(LOG)2-(POG)4==
	<StructureSection load='2drx' size='340' side='right' caption='[[2drx]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2drx' size='340' side='right' caption='[[2drx]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2drt\|2drt]], [[1v4f\|1v4f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2drt\|2drt]], [[1v4f\|1v4f]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [http://pdbe.org/2drx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [http://www.ebi.ac.uk/pdbsum/2drx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [http://pdbe.org/2drx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [http://www.ebi.ac.uk/pdbsum/2drx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2drx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:19, 11 September 2015

OCA — Fri, 11 Sep 2015 01:19:27 GMT

←Older revision		Revision as of 01:19, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2drt\|2drt]], [[1v4f\|1v4f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2drt\|2drt]], [[1v4f\|1v4f]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [http://www.ebi.ac.uk/pdbsum/2drx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [http://pdbe.org/2drx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [http://www.ebi.ac.uk/pdbsum/2drx PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2drx" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:44, 22 December 2014

OCA — Mon, 22 Dec 2014 06:44:46 GMT

←Older revision		Revision as of 06:44, 22 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2drx\| PDB=2drx \| SCENE= }}~~	+	==Structure Analysis of (POG)4-(LOG)2-(POG)4==
-	===Structure Analysis of (POG)4-(LOG)2-(POG)4===	+	<StructureSection load='2drx' size='340' side='right' caption='[[2drx]], [[Resolution\|resolution]] 1.40Å' scene=''>
-	~~{{ABSTRACT_PUBMED_17373653}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DRX FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2drt\|2drt]], [[1v4f\|1v4f]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2drx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2drx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2drx RCSB], [http://www.ebi.ac.uk/pdbsum/2drx PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Single crystal structures of host-guest peptides, (Pro-Hyp-Gly)(4)-Leu-Hyp-Gly-(Pro-Hyp-Gly)(5) (LOG1) and (Pro-Hyp-Gly)(4)- (Leu-Hyp-Gly)(2)-(Pro-Hyp-Gly)(4) (LOG2), have been determined at 1.6 A and 1.4 A resolution, respectively. In these crystals, the side chain conformations of the Leu residues were (+)gauche-trans. This conformational preference for the Leu side chain in the Leu-Hyp-Gly sequence was explained by stereochemical considerations together with statistical analysis of Protein Data Bank data. In the (+)gauche-trans conformation, the Leu side chain can protrude along the radial direction of the rod-like triple-helical molecule. One strong hydrophobic interaction of the Leu residue was observed between adjacent molecules in the LOG2 crystal. Because the Leu-Hyp-Gly sequence is one of the most frequently occurring triplets in Type I collagen, this strong hydrophobic interaction can be expected in a fibrillar structure of native collagen. All the Leu residues in the asymmetric unit of the LOG1 and LOG2 crystals had water molecules hydrogen bonded to their NH. These water molecules made three additional hydrogen bonds with the Hyp OH, the Gly O[double bond]C, and a water molecule in the second hydration shell, forming a tetrahedral coordination of hydrogen bonds, which allows a smaller mean-square displacement factor of this water oxygen atom than those of other water molecules. These hydrogen bonds stabilize the molecular and packing structures by forming one O[double bond]C(Gly)---W---OH(Hyp) intra-molecular linkage and two NH(Leu)---W---O[double bond]C(Gly) and NH(Leu)---W---OH(Hyp) inter-molecular linkages.

-	~~==About this Structure==~~	+	Unique side chain conformation of a Leu residue in a triple-helical structure.,Okuyama K, Narita H, Kawaguchi T, Noguchi K, Tanaka Y, Nishino N Biopolymers. 2007 Jun 15;86(3):212-21. PMID:17373653<ref>PMID:17373653</ref>
-	~~[[2drx]] is~~ a ~~3 chain~~ structure. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann.ac.il~~/~~oca-bin/ocashort?id=2DRX OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:017373653</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Okuyama, K.]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Okuyama, K]]
	[[Category: Collagen]]		[[Category: Collagen]]
	[[Category: Leu]]		[[Category: Leu]]
	[[Category: Structural protein]]		[[Category: Structural protein]]
	[[Category: Triple helix]]		[[Category: Triple helix]]

OCA at 08:38, 23 April 2014

OCA — Wed, 23 Apr 2014 08:38:15 GMT

←Older revision		Revision as of 08:38, 23 April 2014
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-	[[Image:2drx.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_2drx", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2drx\| PDB=2drx \| SCENE= }}		{{STRUCTURE_2drx\| PDB=2drx \| SCENE= }}
-
	===Structure Analysis of (POG)4-(LOG)2-(POG)4===		===Structure Analysis of (POG)4-(LOG)2-(POG)4===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17373653}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17373653 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17373653}}		{{ABSTRACT_PUBMED_17373653}}

Line 22:		Line 7:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:017373653</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017373653</ref><references group="xtra"/><references/>
	[[Category: Okuyama, K.]]		[[Category: Okuyama, K.]]
	[[Category: Collagen]]		[[Category: Collagen]]

OCA: Protected "2drx" [edit=sysop:move=sysop]

OCA — Wed, 15 Feb 2012 05:48:56 GMT

Protected "2drx" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:48, 15 February 2012

OCA at 05:48, 15 February 2012

OCA — Wed, 15 Feb 2012 05:48:54 GMT

←Older revision		Revision as of 05:48, 15 February 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2drx.png\|left\|200px]]		[[Image:2drx.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA].	+	[[2drx]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DRX OCA].

	==Reference==		==Reference==
-	~~Unique side chain conformation of a Leu residue in a triple-helical structure., Okuyama K, Narita H, Kawaguchi T, Noguchi K, Tanaka Y, Nishino N, Biopolymers. 2007 Jun 15;86(3):212-21.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~17373653 17373653]~~	+	<ref group="xtra">PMID:017373653</ref><references group="xtra"/>
	[[Category: Okuyama, K.]]		[[Category: Okuyama, K.]]
	[[Category: Collagen]]		[[Category: Collagen]]
	[[Category: Leu]]		[[Category: Leu]]
		+	[[Category: Structural protein]]
	[[Category: Triple helix]]		[[Category: Triple helix]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:26:41 2008''

OCA at 13:26, 28 July 2008

OCA — Mon, 28 Jul 2008 13:26:46 GMT

←Older revision		Revision as of 13:26, 28 July 2008
Line 1:		Line 1:
-	[[Image:2drx.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2drx.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_2drx\| PDB=2drx \| SCENE= }}		{{STRUCTURE_2drx\| PDB=2drx \| SCENE= }}

-	~~'''~~Structure Analysis of (POG)4-(LOG)2-(POG)4~~'''~~	+	===Structure Analysis of (POG)4-(LOG)2-(POG)4===


-	~~==Overview==~~	+	<!--
-	~~Single crystal structures of host~~-~~guest peptides, (Pro~~-~~Hyp-Gly)(4)-Leu-Hyp-Gly-(Pro-Hyp-Gly)(5) (LOG1) and (Pro-Hyp-Gly)(4)- (Leu-Hyp-Gly)(2)-(Pro-Hyp-Gly)(4) (LOG2)~~, ~~have been determined at 1.6 A and 1.4 A resolution, respectively. In these crystals~~, the ~~side chain conformations of~~ the ~~Leu residues were~~ (~~+)gauche-trans~~. ~~This conformational preference for the Leu side chain in the Leu-Hyp-Gly sequence was explained by stereochemical considerations together with statistical analysis of Protein Data Bank data~~. ~~In the (+~~)~~gauche-trans conformation~~, the Leu side chain can protrude along the radial direction of the rod-like triple-helical molecule. One strong hydrophobic interaction of the Leu residue was observed between adjacent molecules in the LOG2 crystal. Because the Leu-Hyp-Gly sequence is ~~one of~~ the ~~most frequently occurring triplets in Type I collagen, this strong hydrophobic interaction can be expected in a fibrillar structure of native collagen~~. All the Leu residues in the asymmetric unit of the LOG1 and LOG2 crystals had water molecules hydrogen bonded to their NH. These water molecules made three additional hydrogen bonds with the Hyp OH, the Gly O[double bond]C, and a water molecule in the second hydration shell, forming a tetrahedral coordination of hydrogen bonds, which allows a smaller mean-~~square displacement factor of this water oxygen atom than those of other water molecules. These hydrogen bonds stabilize the molecular and packing structures by forming one O[double bond]C(Gly)~~-~~--W---OH(Hyp) intra-molecular linkage and two NH(Leu)---W---O[double bond]C(Gly) and NH(Leu)---W---OH(Hyp) inter-molecular linkages.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_17373653}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 17373653 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_17373653}}

	==About this Structure==		==About this Structure==
Line 24:		Line 28:
	[[Category: Leu]]		[[Category: Leu]]
	[[Category: Triple helix]]		[[Category: Triple helix]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 01~~:03:50 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:26:41 2008''