2e35 - Revision history

OCA at 18:46, 29 May 2024

OCA — Wed, 29 May 2024 18:46:48 GMT

←Older revision		Revision as of 18:46, 29 May 2024
Line 1:		Line 1:

	==the minimized average structure of L11 with rg refinement==		==the minimized average structure of L11 with rg refinement==
-	<StructureSection load='2e35' size='340' side='right'caption='[[2e35~~]], [[NMR_Ensembles_of_Models \| 1 NMR models~~]]' scene=''>	+	<StructureSection load='2e35' size='340' side='right'caption='[[2e35]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E35 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E35 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'>[[2e34\|2e34]], [[2e36\|2e36]]</div~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [https://pdbe.org/2e35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [https://www.ebi.ac.uk/pdbsum/2e35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e35 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [https://pdbe.org/2e35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [https://www.ebi.ac.uk/pdbsum/2e35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e35 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RL11_THETH RL11_THETH]] This protein binds directly to 23S ribosomal RNA (By similarity).	+	[https://www.uniprot.org/uniprot/RL11_THETH RL11_THETH] This protein binds directly to 23S ribosomal RNA (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Choli-Papadopoulous, T]]	+	[[Category: Thermus thermophilus]]
-	[[Category: Draper~~, D E~~]]	+	[[Category: Choli-Papadopoulous T]]
-	[[Category: Krueger, S]]	+	[[Category: Draper DE]]
-	[[Category: Lee, D]]	+	[[Category: Krueger S]]
-	[[Category: Markus~~, M A~~]]	+	[[Category: Lee D]]
-	[[Category: Schwieters~~, C D~~]]	+	[[Category: Markus MA]]
-	[[Category: Walsh~~, J D~~]]	+	[[Category: Schwieters CD]]
-	[[Category: Wang~~, Y X~~]]	+	[[Category: Walsh JD]]
-	[[Category: Yu, P]]	+	[[Category: Wang YX]]
-	~~[[Category: Energy-minimized average structure]]~~	+	[[Category: Yu P]]
-	~~[[Category: L11]]~~	+
-	~~[[Category: Rg]]~~	+
-	~~[[Category: Rna binding protein~~]]	+

OCA at 06:41, 9 March 2022

OCA — Wed, 09 Mar 2022 06:41:30 GMT

←Older revision		Revision as of 06:41, 9 March 2022
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Ribosomal protein L11\|Ribosomal protein L11]]	+	*[[Ribosomal protein L11 3D structures\|Ribosomal protein L11 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:20, 15 December 2021

OCA — Wed, 15 Dec 2021 17:20:13 GMT

←Older revision		Revision as of 17:20, 15 December 2021
Line 3:		Line 3:
	<StructureSection load='2e35' size='340' side='right'caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='2e35' size='340' side='right'caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2E35 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E35 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2e34\|2e34]], [[2e36\|2e36]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [~~http~~://pdbe.org/2e35 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2e35 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2e35 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [https://pdbe.org/2e35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [https://www.ebi.ac.uk/pdbsum/2e35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e35 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RL11_THETH RL11_THETH]] This protein binds directly to 23S ribosomal RNA (By similarity).	+	[[https://www.uniprot.org/uniprot/RL11_THETH RL11_THETH]] This protein binds directly to 23S ribosomal RNA (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:26, 11 March 2020

OCA — Wed, 11 Mar 2020 08:26:47 GMT

←Older revision		Revision as of 08:26, 11 March 2020
Line 1:		Line 1:

	==the minimized average structure of L11 with rg refinement==		==the minimized average structure of L11 with rg refinement==
-	<StructureSection load='2e35' size='340' side='right' caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>	+	<StructureSection load='2e35' size='340' side='right'caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]		[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
		+	[[Category: Large Structures]]
	[[Category: Choli-Papadopoulous, T]]		[[Category: Choli-Papadopoulous, T]]
	[[Category: Draper, D E]]		[[Category: Draper, D E]]

OCA at 06:51, 6 June 2018

OCA — Wed, 06 Jun 2018 06:51:40 GMT

←Older revision		Revision as of 06:51, 6 June 2018
Line 1:		Line 1:
		+
	==the minimized average structure of L11 with rg refinement==		==the minimized average structure of L11 with rg refinement==
	<StructureSection load='2e35' size='340' side='right' caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='2e35' size='340' side='right' caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [http://pdbe.org/2e35 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [http://www.ebi.ac.uk/pdbsum/2e35 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [http://pdbe.org/2e35 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [http://www.ebi.ac.uk/pdbsum/2e35 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2e35 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e35_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e35_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:06, 10 February 2016

OCA — Wed, 10 Feb 2016 03:06:53 GMT

←Older revision		Revision as of 03:06, 10 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e35 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:46, 11 September 2015

OCA — Fri, 11 Sep 2015 04:46:26 GMT

←Older revision		Revision as of 04:46, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2e35' size='340' side='right' caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='2e35' size='340' side='right' caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus Thermus thermophilus~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [http://www.ebi.ac.uk/pdbsum/2e35 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [http://pdbe.org/2e35 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [http://www.ebi.ac.uk/pdbsum/2e35 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2e35" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ribosomal protein L11\|Ribosomal protein L11]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermus thermophilus~~]]	+	[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
	[[Category: Choli-Papadopoulous, T]]		[[Category: Choli-Papadopoulous, T]]
	[[Category: Draper, D E]]		[[Category: Draper, D E]]

OCA at 11:22, 25 December 2014

OCA — Thu, 25 Dec 2014 11:22:18 GMT

←Older revision		Revision as of 11:22, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [http://www.ebi.ac.uk/pdbsum/2e35 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [http://www.ebi.ac.uk/pdbsum/2e35 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RL11_THETH RL11_THETH]] This protein binds directly to 23S ribosomal RNA (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
-
-	==See Also==
-	*[[Ribosomal protein L11\|Ribosomal protein L11]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
-	[[Category: Choli-Papadopoulous, T.]]	+	[[Category: Choli-Papadopoulous, T]]
-	[[Category: Draper, D E.]]	+	[[Category: Draper, D E]]
-	[[Category: Krueger, S.]]	+	[[Category: Krueger, S]]
-	[[Category: Lee, D.]]	+	[[Category: Lee, D]]
-	[[Category: Markus, M A.]]	+	[[Category: Markus, M A]]
-	[[Category: Schwieters, C D.]]	+	[[Category: Schwieters, C D]]
-	[[Category: Walsh, J D.]]	+	[[Category: Walsh, J D]]
-	[[Category: Wang, Y X.]]	+	[[Category: Wang, Y X]]
-	[[Category: Yu, P.]]	+	[[Category: Yu, P]]
	[[Category: Energy-minimized average structure]]		[[Category: Energy-minimized average structure]]
	[[Category: L11]]		[[Category: L11]]
	[[Category: Rg]]		[[Category: Rg]]
	[[Category: Rna binding protein]]		[[Category: Rna binding protein]]

OCA at 02:23, 29 September 2014

OCA — Mon, 29 Sep 2014 02:23:58 GMT

←Older revision		Revision as of 02:23, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2e35.~~png~~\|~~left~~\|200px]]	+	==the minimized average structure of L11 with rg refinement==
		+	<StructureSection load='2e35' size='340' side='right' caption='[[2e35]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E35 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e34\|2e34]], [[2e36\|2e36]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e35 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e35 RCSB], [http://www.ebi.ac.uk/pdbsum/2e35 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e3/2e35_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The L11 binding site is one of the most important functional sites in the ribosome. The N-terminal domain of L11 has been implicated as a "reversible switch" in facilitating the coordinated movements associated with EF-G-driven GTP hydrolysis. The reversible switch mechanism has been hypothesized to require conformational flexibility involving re-orientation and re-positioning of the two L11 domains, and warrants a close examination of the structure and dynamics of L11. Here we report the solution structure of free L11, and relaxation studies of free L11, L11 complexed to its 58 nt RNA recognition site, and L11 in a ternary complex with the RNA and thiostrepton antibiotic. The binding site of thiostrepton on L11 was also defined by analysis of structural and dynamics data and chemical shift mapping. The conclusions of this work are as follows: first, the binding of L11 to RNA leads to sizable conformation changes in the regions flanking the linker and in the hinge area that links a beta-sheet and a 3(10)-helix-turn-helix element in the N terminus. Concurrently, the change in the relative orientation may lead to re-positioning of the N terminus, as implied by a decrease of radius of gyration from 18.5 A to 16.2 A. Second, the regions, which undergo large conformation changes, exhibit motions on milliseconds-microseconds or nanoseconds-picoseconds time scales. Third, binding of thiostrepton results in more rigid conformations near the linker (Thr71) and near its putative binding site (Leu12). Lastly, conformational changes in the putative thiostrepton binding site are implicated by the re-emergence of cross-correlation peaks in the spectrum of the ternary complex, which were missing in that of the binary complex. Our combined analysis of both the chemical shift perturbation and dynamics data clearly indicates that thiostrepton binds to a pocket involving residues in the 3(10)-helix in L11.

-	~~{{STRUCTURE_2e35\| PDB=2e35 \| SCENE= }}~~	+	The structure of free L11 and functional dynamics of L11 in free, L11-rRNA(58 nt) binary and L11-rRNA(58 nt)-thiostrepton ternary complexes.,Lee D, Walsh JD, Yu P, Markus MA, Choli-Papadopoulou T, Schwieters CD, Krueger S, Draper DE, Wang YX J Mol Biol. 2007 Apr 6;367(4):1007-22. Epub 2007 Jan 10. PMID:17292917<ref>PMID:17292917</ref>

-	~~===~~the ~~minimized average structure of L11 with rg refinement===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17292917}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2e35]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA].~~	+

	==See Also==		==See Also==
	*[[Ribosomal protein L11\|Ribosomal protein L11]]		*[[Ribosomal protein L11\|Ribosomal protein L11]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017292917<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Choli-Papadopoulous, T.]]		[[Category: Choli-Papadopoulous, T.]]

OCA at 16:06, 20 October 2012

OCA — Sat, 20 Oct 2012 16:06:43 GMT

←Older revision		Revision as of 16:06, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2e35]] is a 1 chain structure ~~of [[Ribosomal protein L11]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA].	+	[[2e35]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E35 OCA].

	==See Also==		==See Also==