2e6g - Revision history

OCA at 08:35, 25 October 2023

OCA — Wed, 25 Oct 2023 08:35:46 GMT

←Older revision		Revision as of 08:35, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='2e6g' size='340' side='right'caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2e6g' size='340' side='right'caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Thet8 Thet8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E6G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E6G FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [https://pdbe.org/2e6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [https://www.ebi.ac.uk/pdbsum/2e6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6g ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [https://pdbe.org/2e6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [https://www.ebi.ac.uk/pdbsum/2e6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SURE_THET8 SURE_THET8]] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).	+	[https://www.uniprot.org/uniprot/SURE_THET8 SURE_THET8] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: 5'-nucleotidase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Thet8~~]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Iwasaki, W]]	+	[[Category: Iwasaki W]]
-	[[Category: Miki, K]]	+	[[Category: Miki K]]
-	~~[[Category: Complexed with phosphate ion]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Sure protein~~]]	+

OCA at 17:21, 15 December 2021

OCA — Wed, 15 Dec 2021 17:21:11 GMT

←Older revision		Revision as of 17:21, 15 December 2021
Line 3:		Line 3:
	<StructureSection load='2e6g' size='340' side='right'caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2e6g' size='340' side='right'caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2E6G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E6G FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [~~http~~://pdbe.org/2e6g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2e6g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6g ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [https://pdbe.org/2e6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [https://www.ebi.ac.uk/pdbsum/2e6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SURE_THET8 SURE_THET8]] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).	+	[[https://www.uniprot.org/uniprot/SURE_THET8 SURE_THET8]] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:28, 11 March 2020

OCA — Wed, 11 Mar 2020 08:28:18 GMT

←Older revision		Revision as of 08:28, 11 March 2020
Line 1:		Line 1:

	==Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate==		==Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate==
-	<StructureSection load='2e6g' size='340' side='right' caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='2e6g' size='340' side='right'caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6G FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6G FirstGlance]. <br>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: 5'-nucleotidase]]		[[Category: 5'-nucleotidase]]
		+	[[Category: Large Structures]]
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Iwasaki, W]]		[[Category: Iwasaki, W]]

OCA at 07:09, 6 June 2018

OCA — Wed, 06 Jun 2018 07:09:45 GMT

←Older revision		Revision as of 07:09, 6 June 2018
Line 1:		Line 1:
		+
	==Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate==		==Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate==
	<StructureSection load='2e6g' size='340' side='right' caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2e6g' size='340' side='right' caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [http://pdbe.org/2e6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [http://www.ebi.ac.uk/pdbsum/2e6g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [http://pdbe.org/2e6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [http://www.ebi.ac.uk/pdbsum/2e6g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6g ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e6g_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e6g_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e6g ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:51, 12 September 2015

OCA — Sat, 12 Sep 2015 01:51:17 GMT

←Older revision		Revision as of 01:51, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2e6g' size='340' side='right' caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2e6g' size='340' side='right' caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus_hb8 Thermus thermophilus hb8~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6G FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [http://www.ebi.ac.uk/pdbsum/2e6g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [http://pdbe.org/2e6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [http://www.ebi.ac.uk/pdbsum/2e6g PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2e6g" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: 5'-nucleotidase]]		[[Category: 5'-nucleotidase]]
-	[[Category: ~~Thermus thermophilus hb8~~]]	+	[[Category: Thet8]]
	[[Category: Iwasaki, W]]		[[Category: Iwasaki, W]]
	[[Category: Miki, K]]		[[Category: Miki, K]]

OCA at 22:16, 25 December 2014

OCA — Thu, 25 Dec 2014 22:16:20 GMT

←Older revision		Revision as of 22:16, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6G FirstGlance]. <br>		<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6G FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [http://www.ebi.ac.uk/pdbsum/2e6g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [http://www.ebi.ac.uk/pdbsum/2e6g PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SURE_THET8 SURE_THET8]] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	[[Category: 5'-nucleotidase]]		[[Category: 5'-nucleotidase]]
	[[Category: Thermus thermophilus hb8]]		[[Category: Thermus thermophilus hb8]]
-	[[Category: Iwasaki, W.]]	+	[[Category: Iwasaki, W]]
-	[[Category: Miki, K.]]	+	[[Category: Miki, K]]
	[[Category: Complexed with phosphate ion]]		[[Category: Complexed with phosphate ion]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Sure protein]]		[[Category: Sure protein]]

OCA at 02:08, 30 September 2014

OCA — Tue, 30 Sep 2014 02:08:38 GMT

←Older revision		Revision as of 02:08, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2e6g.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate==
		+	<StructureSection load='2e6g' size='340' side='right' caption='[[2e6g]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2E6G FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2e69\|2e69]], [[2e6b\|2e6b]], [[2e6c\|2e6c]], [[2e6e\|2e6e]], [[2e6h\|2e6h]], [[1j9j\|1j9j]], [[1ilv\|1ilv]], [[1j9l\|1j9l]], [[1j9k\|1j9k]], [[1l5x\|1l5x]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2e6g RCSB], [http://www.ebi.ac.uk/pdbsum/2e6g PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e6g_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The stationary phase survival protein SurE is a metal ion-dependent phosphatase distributed among eubacteria, archaea, and eukaryotes. In Escherichia coli, SurE has activities as nucleotidase and exopolyphosphatase, and is thought to be involved in stress response. However, its physiological role and reaction mechanism are unclear. We report here the crystal structures of the tetramer of SurE from Thermus thermophilus HB8 (TtSurE) both alone and crystallized with Mn(2+) and substrate AMP. In the presence of Mn(2+) and AMP, differences between the protomers were observed in the active site and in the loop located near the active site; AMP-bound active sites with the loops in a novel open conformation were found in the two protomers, and AMP-free active sites with the loops in a conventional closed conformation were found in the other two protomers. The two loops in the open conformation are entwined with each other, and this entwining is suggested to be required for enzymatic activity by site-directed mutagenesis. TtSurE exists as an equilibrium mixture of dimer and tetramer in solution. The loop-entwined structure indicates that SurE acts as a tetramer. The structural features and the absence of negative cooperativity imply the half-of-the-sites reactivity mechanism resulting from a pre-existing tendency toward structural asymmetry.

-	~~{{STRUCTURE_2e6g\| PDB=2e6g \| SCENE= }}~~	+	Crystal structure of the stationary phase survival protein SurE with metal ion and AMP.,Iwasaki W, Miki K J Mol Biol. 2007 Aug 3;371(1):123-36. Epub 2007 May 10. PMID:17561111<ref>PMID:17561111</ref>

-	~~===Crystal structure~~ of the ~~stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17561111}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2e6g]] is a 12 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017561111<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: 5'-nucleotidase]]		[[Category: 5'-nucleotidase]]
	[[Category: Thermus thermophilus hb8]]		[[Category: Thermus thermophilus hb8]]

OCA: Protected "2e6g" [edit=sysop:move=sysop]

OCA — Sun, 06 Jan 2013 11:21:41 GMT

Protected "2e6g" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:21, 6 January 2013

OCA at 11:21, 6 January 2013

OCA — Sun, 06 Jan 2013 11:21:37 GMT

←Older revision		Revision as of 11:21, 6 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2e6g.png\|left\|200px]]		[[Image:2e6g.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2e6g", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2e6g\| PDB=2e6g \| SCENE= }}		{{STRUCTURE_2e6g\| PDB=2e6g \| SCENE= }}

	===Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate===		===Crystal structure of the stationary phase survival protein SurE from Thermus thermophilus HB8 in complex with phosphate===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17561111}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17561111 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17561111}}		{{ABSTRACT_PUBMED_17561111}}

	==About this Structure==		==About this Structure==
-	~~2E6G~~ is a 12 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus~~ Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA].	+	[[2e6g]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17561111~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017561111</ref><references group="xtra"/>
	[[Category: 5'-nucleotidase]]		[[Category: 5'-nucleotidase]]
-	[[Category: Thermus thermophilus]]	+	[[Category: Thermus thermophilus hb8]]
	[[Category: Iwasaki, W.]]		[[Category: Iwasaki, W.]]
	[[Category: Miki, K.]]		[[Category: Miki, K.]]
Line 31:		Line 19:
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Sure protein]]		[[Category: Sure protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:31:34 2009''

OCA at 07:31, 18 February 2009

OCA — Wed, 18 Feb 2009 07:31:35 GMT

←Older revision		Revision as of 07:31, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2E6G is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA].	+	2E6G is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6G OCA].

	==Reference==		==Reference==
-	~~Crystal structure of the stationary phase survival protein SurE with metal ion and AMP., Iwasaki W, Miki K, J Mol Biol. 2007 Aug 3;371(1):123-36. Epub 2007 May 10.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17561111 17561111]~~	+	<ref group="xtra">PMID:17561111</ref><references group="xtra"/>
	[[Category: 5'-nucleotidase]]		[[Category: 5'-nucleotidase]]
-	[[Category: Single protein]]
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Iwasaki, W.]]		[[Category: Iwasaki, W.]]
Line 33:		Line 32:
	[[Category: Sure protein]]		[[Category: Sure protein]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 15~~:47:~~46 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:31:34 2009''