2ekw - Revision history

OCA: Redirecting to 3i5i

OCA — Wed, 10 Feb 2010 15:06:14 GMT

Redirecting to 3i5i

←Older revision		Revision as of 15:06, 10 February 2010
Line 1:		Line 1:
-	~~{{Seed}}~~	+	#REDIRECT [[3i5i]] This PDB entry is obsolete and replaced by 3i5i
-	[[~~Image:2ekw.png\|left\|200px~~]]	+
-		+
-	~~<!--~~	+
-	~~The line below this paragraph, containing "STRUCTURE_2ekw", creates the "Structure Box" on the page.~~	+
-	~~You may change the~~ PDB ~~parameter (which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page~~ is ~~loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	~~-->~~	+
-	~~{{STRUCTURE_2ekw\| PDB=2ekw \| SCENE= }}~~	+
-		+
-	~~===The crystal structure of squid myosin S1 in the presence of SO4 2-===~~	+
-		+
-		+
-	~~<!--~~	+
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_17502101}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at http://www.pubmed.gov), where 17502101 is the PubMed ID number.~~	+
-	~~-->~~	+
-	~~{{ABSTRACT_PUBMED_17502101}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~2EKW is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Loligo_pealei Loligo pealei]~~ and ~~[http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].~~	+
-		+
-	~~==Reference==~~	+
-	~~<ref group="xtra">PMID:17502101</ref><references group="xtra"/>~~	+
-	~~[[Category: Loligo pealei]]~~	+
-	~~[[Category: Todarodes pacificus]]~~	+
-	~~[[Category: Cohen, C.]]~~	+
-	~~[[Category: Neall-Hennessey, E O.]]~~	+
-	~~[[Category: Reshetnikova, L.]]~~	+
-	~~[[Category: Yang, Y.]]~~	+
-	~~[[Category: Contractile protein]]~~	+
-	~~[[Category: Myosin s1]]~~	+
-	~~[[Category: Nucleotide free]]~~	+
-	~~[[Category: Rigor-like]]~~	+
-	~~[[Category: Squid]]~~	+
-		+
-	~~''Page seeded~~ by ~~[http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:12:13 2009''~~	+

OCA at 16:12, 16 February 2009

OCA — Mon, 16 Feb 2009 16:12:15 GMT

←Older revision		Revision as of 16:12, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2EKW is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Loligo_pealei Loligo pealei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].	+	2EKW is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Loligo_pealei Loligo pealei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].

	==Reference==		==Reference==
-	Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17502101 17502101]~~	+	<ref group="xtra">PMID:17502101</ref><references group="xtra"/>
	[[Category: Loligo pealei]]		[[Category: Loligo pealei]]
-	[[Category: Protein complex]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]
	[[Category: Cohen, C.]]		[[Category: Cohen, C.]]
Line 37:		Line 36:
	[[Category: Squid]]		[[Category: Squid]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 21~~:49:~~20 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:12:13 2009''

OCA at 18:49, 27 July 2008

OCA — Sun, 27 Jul 2008 18:49:25 GMT

←Older revision		Revision as of 18:49, 27 July 2008
Line 1:		Line 1:
-	[[Image:2ekw.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2ekw.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2ekw\| PDB=2ekw \| SCENE= }}		{{STRUCTURE_2ekw\| PDB=2ekw \| SCENE= }}

-	~~'''~~The crystal structure of squid myosin S1 in the presence of SO4 2-~~'''~~	+	===The crystal structure of squid myosin S1 in the presence of SO4 2-===


-	~~==Overview==~~	+	<!--
-	~~Unlike processive cellular motors such as myosin V, whose structure has recently been determined in a "rigor~~-like" conformation, myosin II from contracting muscle filaments necessarily spends most of its time detached from actin. By using squid and sea scallop sources, however, we have now obtained similar rigor-~~like atomic structures for muscle myosin heads (S1).~~ The ~~significance of the hallmark closed actin-binding cleft in these crystal structures is supported here by actin/S1-binding studies. These structures reveal how different duty ratios~~, ~~and hence cellular functions~~, of the ~~myosin isoforms may be accounted for, in part,~~ on ~~the basis of detailed differences in interdomain contacts~~. ~~Moreover, the rigor-like position of switch II turns out to be unique for myosin V~~. ~~The overall arrangements of subdomains in the motor are relatively conserved in each of the known contractile states~~, ~~and we explore qualitatively~~ the ~~energetics of these states~~.	+	The line below this paragraph, {{ABSTRACT_PUBMED_17502101}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 17502101 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_17502101}}

	==About this Structure==		==About this Structure==
Line 32:		Line 36:
	[[Category: Rigor-like]]		[[Category: Rigor-like]]
	[[Category: Squid]]		[[Category: Squid]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun ~~May 4 02~~:41:59 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 21:49:20 2008''

OCA at 23:42, 3 May 2008

OCA — Sat, 03 May 2008 23:42:00 GMT

←Older revision		Revision as of 23:42, 3 May 2008
Line 1:		Line 1:
	[[Image:2ekw.jpg\|left\|200px]]		[[Image:2ekw.jpg\|left\|200px]]

-	~~{{Structure~~	+	<!--
-	~~\|PDB= 2ekw \|SIZE=350\|CAPTION= <scene name='initialview01'>2ekw</scene>~~, ~~resolution 3~~.~~3Å~~	+	The line below this paragraph, containing "STRUCTURE_2ekw", creates the "Structure Box" on the page.
-	~~\|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+C+2001'>AC2</scene>~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <~~scene ~~name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	~~\|ACTIVITY=~~	+	or leave the SCENE parameter empty for the default display.
-	~~\|GENE=~~	+	-->
-	\|~~DOMAIN~~=	+	{{STRUCTURE_2ekw\| PDB=2ekw \| SCENE= }}
-	\|~~RELATEDENTRY~~=~~[[2ekv\|2EKV]]~~	+
-	\|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ekw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ekw OCA], [http://www.ebi.ac.uk/pdbsum/2ekw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ekw RCSB]</span>	+
-	}}	+

	'''The crystal structure of squid myosin S1 in the presence of SO4 2-'''		'''The crystal structure of squid myosin S1 in the presence of SO4 2-'''
Line 30:		Line 27:
	[[Category: Reshetnikova, L.]]		[[Category: Reshetnikova, L.]]
	[[Category: Yang, Y.]]		[[Category: Yang, Y.]]
-	[[Category: ~~contractile~~ protein]]	+	[[Category: Contractile protein]]
-	[[Category: ~~myosin~~ s1]]	+	[[Category: Myosin s1]]
-	[[Category: ~~nucleotide~~ free]]	+	[[Category: Nucleotide free]]
-	[[Category: ~~rigor~~-like]]	+	[[Category: Rigor-like]]
-	[[Category: ~~squid~~]]	+	[[Category: Squid]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 02:41:59 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Mar 31~~ 02:50:35 2008''	+

OCA at 23:50, 30 March 2008

OCA — Sun, 30 Mar 2008 23:50:38 GMT

←Older revision		Revision as of 23:50, 30 March 2008
Line 4:		Line 4:
	\|PDB= 2ekw \|SIZE=350\|CAPTION= <scene name='initialview01'>2ekw</scene>, resolution 3.3Å		\|PDB= 2ekw \|SIZE=350\|CAPTION= <scene name='initialview01'>2ekw</scene>, resolution 3.3Å
	\|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+C+2001'>AC2</scene>		\|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+C+2001'>AC2</scene>
-	\|LIGAND= <scene name='pdbligand=~~SO4~~:~~SULFATE~~+ION'>~~SO4~~</scene> ~~and~~ <scene name='pdbligand=CA:~~CALCIUM~~ ION'>CA</scene>	+	\|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
	\|ACTIVITY=		\|ACTIVITY=
	\|GENE=		\|GENE=
		+	\|DOMAIN=
		+	\|RELATEDENTRY=[[2ekv\|2EKV]]
		+	\|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ekw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ekw OCA], [http://www.ebi.ac.uk/pdbsum/2ekw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ekw RCSB]</span>
	}}		}}

Line 16:		Line 19:

	==About this Structure==		==About this Structure==
-	2EKW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/~~Loligo_plei~~ Loligo ~~plei~~] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].	+	2EKW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Loligo_pealei Loligo pealei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].

	==Reference==		==Reference==
	Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17502101 17502101]		Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17502101 17502101]
-	[[Category: Loligo ~~plei~~]]	+	[[Category: Loligo pealei]]
	[[Category: Protein complex]]		[[Category: Protein complex]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]
Line 27:		Line 30:
	[[Category: Reshetnikova, L.]]		[[Category: Reshetnikova, L.]]
	[[Category: Yang, Y.]]		[[Category: Yang, Y.]]
-	[[Category: CA]]
-	[[Category: SO4]]
	[[Category: contractile protein]]		[[Category: contractile protein]]
	[[Category: myosin s1]]		[[Category: myosin s1]]
Line 35:		Line 36:
	[[Category: squid]]		[[Category: squid]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu~~ Mar ~~20 16~~:41:29 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:50:35 2008''

OCA at 14:41, 20 March 2008

OCA — Thu, 20 Mar 2008 14:41:30 GMT

←Older revision		Revision as of 14:41, 20 March 2008
Line 1:		Line 1:
-	[[Image:2ekw.jpg\|left\|200px]]~~<br /><applet load~~="2ekw~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~	+	[[Image:2ekw.jpg\|left\|200px]]
-	~~caption="~~2ekw, resolution 3.3Å" />	+
-	'''The crystal structure of squid myosin S1 in the presence of SO4 2-'''~~<br />~~	+	{{Structure
		+	\|PDB= 2ekw \|SIZE=350\|CAPTION= <scene name='initialview01'>2ekw</scene>, resolution 3.3Å
		+	\|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+C+2001'>AC2</scene>
		+	\|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
		+	\|ACTIVITY=
		+	\|GENE=
		+	}}
		+
		+	'''The crystal structure of squid myosin S1 in the presence of SO4 2-'''
		+

	==Overview==		==Overview==
Line 7:		Line 16:

	==About this Structure==		==About this Structure==
-	2EKW is a [~~http://en.wikipedia.org/wiki/Protein_complex~~ Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Loligo_plei Loligo plei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+C+2001'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].	+	2EKW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Loligo_plei Loligo plei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].

	==Reference==		==Reference==
-	Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~17502101 17502101]	+	Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17502101 17502101]
	[[Category: Loligo plei]]		[[Category: Loligo plei]]
	[[Category: Protein complex]]		[[Category: Protein complex]]
Line 26:		Line 35:
	[[Category: squid]]		[[Category: squid]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 17~~:12:05 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:41:29 2008''

OCA at 15:12, 21 February 2008

OCA — Thu, 21 Feb 2008 15:12:13 GMT

←Older revision		Revision as of 15:12, 21 February 2008
Line 4:		Line 4:

	==Overview==		==Overview==
-	Unlike processive cellular motors such as myosin V, whose structure has, recently been determined in a "rigor-like" conformation, myosin II from, contracting muscle filaments necessarily spends most of its time detached, from actin. By using squid and sea scallop sources, however, we have now, obtained similar rigor-like atomic structures for muscle myosin heads, (S1). The significance of the hallmark closed actin-binding cleft in these, crystal structures is supported here by actin/S1-binding studies. These, structures reveal how different duty ratios, and hence cellular functions, of the myosin isoforms may be accounted for, in part, on the basis of, detailed differences in interdomain contacts. Moreover, the rigor-like, position of switch II turns out to be unique for myosin V. The overall, arrangements of subdomains in the motor are relatively conserved in each, of the known contractile states, and we explore qualitatively the, energetics of these states.	+	Unlike processive cellular motors such as myosin V, whose structure has recently been determined in a "rigor-like" conformation, myosin II from contracting muscle filaments necessarily spends most of its time detached from actin. By using squid and sea scallop sources, however, we have now obtained similar rigor-like atomic structures for muscle myosin heads (S1). The significance of the hallmark closed actin-binding cleft in these crystal structures is supported here by actin/S1-binding studies. These structures reveal how different duty ratios, and hence cellular functions, of the myosin isoforms may be accounted for, in part, on the basis of detailed differences in interdomain contacts. Moreover, the rigor-like position of switch II turns out to be unique for myosin V. The overall arrangements of subdomains in the motor are relatively conserved in each of the known contractile states, and we explore qualitatively the energetics of these states.

	==About this Structure==		==About this Structure==
Line 10:		Line 10:

	==Reference==		==Reference==
-	Rigor-like ~~Structures~~ from ~~Muscle Myosins Reveal Key Mechanical Elements~~ in the ~~Transduction Pathways~~ of ~~This Allosteric Motor~~., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'~~neall~~-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17502101 17502101]	+	Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'Neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17502101 17502101]
	[[Category: Loligo plei]]		[[Category: Loligo plei]]
	[[Category: Protein complex]]		[[Category: Protein complex]]
	[[Category: Todarodes pacificus]]		[[Category: Todarodes pacificus]]
	[[Category: Cohen, C.]]		[[Category: Cohen, C.]]
-	[[Category: Neall-Hennessey, E.O.]]	+	[[Category: Neall-Hennessey, E O.]]
	[[Category: Reshetnikova, L.]]		[[Category: Reshetnikova, L.]]
	[[Category: Yang, Y.]]		[[Category: Yang, Y.]]
Line 26:		Line 26:
	[[Category: squid]]		[[Category: squid]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Feb ~~13 08~~:13:49 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:12:05 2008''

OCA at 06:13, 13 February 2008

OCA — Wed, 13 Feb 2008 06:13:49 GMT

←Older revision		Revision as of 06:13, 13 February 2008
Line 26:		Line 26:
	[[Category: squid]]		[[Category: squid]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb ~~6 17~~:21:55 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 13 08:13:49 2008''

OCA at 15:21, 6 February 2008

OCA — Wed, 06 Feb 2008 15:21:56 GMT

←Older revision		Revision as of 15:21, 6 February 2008
Line 1:		Line 1:
	[[Image:2ekw.jpg\|left\|200px]]<br /><applet load="2ekw" size="350" color="white" frame="true" align="right" spinBox="true"		[[Image:2ekw.jpg\|left\|200px]]<br /><applet load="2ekw" size="350" color="white" frame="true" align="right" spinBox="true"
-	caption="2ekw" />	+	caption="2ekw, resolution 3.3Å" />
-	''''''<br />	+	'''The crystal structure of squid myosin S1 in the presence of SO4 2-'''<br />
		+
		+	==Overview==
		+	Unlike processive cellular motors such as myosin V, whose structure has, recently been determined in a "rigor-like" conformation, myosin II from, contracting muscle filaments necessarily spends most of its time detached, from actin. By using squid and sea scallop sources, however, we have now, obtained similar rigor-like atomic structures for muscle myosin heads, (S1). The significance of the hallmark closed actin-binding cleft in these, crystal structures is supported here by actin/S1-binding studies. These, structures reveal how different duty ratios, and hence cellular functions, of the myosin isoforms may be accounted for, in part, on the basis of, detailed differences in interdomain contacts. Moreover, the rigor-like, position of switch II turns out to be unique for myosin V. The overall, arrangements of subdomains in the motor are relatively conserved in each, of the known contractile states, and we explore qualitatively the, energetics of these states.

	==About this Structure==		==About this Structure==
-	is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA].	+	2EKW is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Loligo_plei Loligo plei] and [http://en.wikipedia.org/wiki/Todarodes_pacificus Todarodes pacificus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:So4+Binding+Site+For+Residue+A+1001'>AC1</scene> and <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+C+2001'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKW OCA].
		+
		+	==Reference==
		+	Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor., Yang Y, Gourinath S, Kovacs M, Nyitray L, Reutzel R, Himmel DM, O'neall-Hennessey E, Reshetnikova L, Szent-Gyorgyi AG, Brown JH, Cohen C, Structure. 2007 May;15(5):553-64. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17502101 17502101]
		+	[[Category: Loligo plei]]
	[[Category: Protein complex]]		[[Category: Protein complex]]
		+	[[Category: Todarodes pacificus]]
		+	[[Category: Cohen, C.]]
		+	[[Category: Neall-Hennessey, E.O.]]
		+	[[Category: Reshetnikova, L.]]
		+	[[Category: Yang, Y.]]
		+	[[Category: CA]]
		+	[[Category: SO4]]
		+	[[Category: contractile protein]]
		+	[[Category: myosin s1]]
		+	[[Category: nucleotide free]]
		+	[[Category: rigor-like]]
		+	[[Category: squid]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 6 15:33:00 2008''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 6 17:21:55 2008''

OCA: New page: 200px
''''''
==About this Structure== is a [h...
OCA — Wed, 06 Feb 2008 13:33:00 GMT

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==About this Structure==
is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA].
[[Category: Protein complex]]

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