2fil - Revision history

OCA at 09:27, 30 August 2023

OCA — Wed, 30 Aug 2023 09:27:36 GMT

←Older revision		Revision as of 09:27, 30 August 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FIL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FIL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.69Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [https://pdbe.org/2fil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [https://www.ebi.ac.uk/pdbsum/2fil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fil ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [https://pdbe.org/2fil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [https://www.ebi.ac.uk/pdbsum/2fil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fil ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:13, 8 February 2023

OCA — Wed, 08 Feb 2023 07:13:13 GMT

←Older revision		Revision as of 07:13, 8 February 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FIL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FIL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=~~NCO~~:~~COBALT~~+~~HEXAMMINE~~(~~III~~)'>~~NCO~~</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~A2M~~:~~2-O-METHYLADENOSINE~~+5-(~~DIHYDROGEN+PHOSPHATE~~)'>~~A2M~~</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene~~></td></tr>~~	+
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [https://pdbe.org/2fil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [https://www.ebi.ac.uk/pdbsum/2fil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fil ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [https://pdbe.org/2fil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [https://www.ebi.ac.uk/pdbsum/2fil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fil ProSAT]</span></td></tr>
	</table>		</table>
Line 23:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Egli, M]]	+	[[Category: Egli M]]
-	[[Category: Li, F]]	+	[[Category: Li F]]
-	~~[[Category: 2'-fluoroarabino acid]]~~	+
-	~~[[Category: A-form dna]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Sugar modification~~]]	+

OCA at 09:54, 5 May 2021

OCA — Wed, 05 May 2021 09:54:46 GMT

←Older revision		Revision as of 09:54, 5 May 2021
Line 3:		Line 3:
	<StructureSection load='2fil' size='340' side='right'caption='[[2fil]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='2fil' size='340' side='right'caption='[[2fil]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FIL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FIL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [~~http~~://pdbe.org/2fil PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2fil PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2fil ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [https://pdbe.org/2fil PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [https://www.ebi.ac.uk/pdbsum/2fil PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fil ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:04, 24 July 2019

OCA — Wed, 24 Jul 2019 09:04:59 GMT

←Older revision		Revision as of 09:04, 24 July 2019
Line 1:		Line 1:

	==Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)==		==Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)==
-	<StructureSection load='2fil' size='340' side='right' caption='[[2fil]], [[Resolution\|resolution]] 1.69Å' scene=''>	+	<StructureSection load='2fil' size='340' side='right'caption='[[2fil]], [[Resolution\|resolution]] 1.69Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FIL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FIL FirstGlance]. <br>
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Egli, M]]		[[Category: Egli, M]]
	[[Category: Li, F]]		[[Category: Li, F]]

OCA at 07:39, 18 October 2017

OCA — Wed, 18 Oct 2017 07:39:08 GMT

←Older revision		Revision as of 07:39, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)==		==Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)==
	<StructureSection load='2fil' size='340' side='right' caption='[[2fil]], [[Resolution\|resolution]] 1.69Å' scene=''>		<StructureSection load='2fil' size='340' side='right' caption='[[2fil]], [[Resolution\|resolution]] 1.69Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [http://pdbe.org/2fil PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [http://www.ebi.ac.uk/pdbsum/2fil PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [http://pdbe.org/2fil PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [http://www.ebi.ac.uk/pdbsum/2fil PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fil ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:38, 11 September 2015

OCA — Fri, 11 Sep 2015 01:38:04 GMT

←Older revision		Revision as of 01:38, 11 September 2015
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [http://www.ebi.ac.uk/pdbsum/2fil PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [http://pdbe.org/2fil PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [http://www.ebi.ac.uk/pdbsum/2fil PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2fil" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:05, 22 December 2014

OCA — Mon, 22 Dec 2014 05:05:19 GMT

←Older revision		Revision as of 05:05, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FIL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FIL FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [http://www.ebi.ac.uk/pdbsum/2fil PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [http://www.ebi.ac.uk/pdbsum/2fil PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Egli, M.]]	+	[[Category: Egli, M]]
-	[[Category: Li, F.]]	+	[[Category: Li, F]]
	[[Category: 2'-fluoroarabino acid]]		[[Category: 2'-fluoroarabino acid]]
	[[Category: A-form dna]]		[[Category: A-form dna]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Sugar modification]]		[[Category: Sugar modification]]

OCA at 06:52, 9 June 2014

OCA — Mon, 09 Jun 2014 06:52:20 GMT

←Older revision		Revision as of 06:52, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~2fil.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)==
		+	<StructureSection load='2fil' size='340' side='right' caption='[[2fil]], [[Resolution\|resolution]] 1.69Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FIL FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=TAF:2-DEOXY-2-FLUORO-ARABINO-FURANOSYL+THYMINE-5-PHOSPHATE'>TAF</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fih\|2fih]], [[2fii\|2fii]], [[2fij\|2fij]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fil OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fil RCSB], [http://www.ebi.ac.uk/pdbsum/2fil PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	2'-Deoxy-2'-fluoro-arabinonucleic acid (FANA) and arabinonucleic acid (ANA) paired to RNA are substrates of RNase H. The conformation of the natural DNA/RNA hybrid substrates appears to be neither A-form nor B-form. Consistent with this, the conformations of FANA and ANA were found to be intermediate between the A- and B-forms. However, FANA opposite RNA is preferred by RNase H over ANA, and the RNA affinity of FANA considerably exceeds that of ANA. By investigating the conformational boundaries of FANA and ANA residues in crystal structures of A- and B-form DNA duplexes at atomic resolution, we demonstrate that FANA and ANA display subtle conformational differences. The structural data provide insight into the structural requirements at the catalytic site of RNase H. They also allow conclusions with regard to the relative importance of stereoelectronic effects and hydration as modulators of RNA affinity.

-	~~{{STRUCTURE_2fil\| PDB=2fil \| SCENE= }}~~	+	2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.,Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M Biochemistry. 2006 Apr 4;45(13):4141-52. PMID:16566588<ref>PMID:16566588</ref>

-	~~===Crystal Structure Analysis~~ of the ~~A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16566588}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2fil]] is a 4 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=2FIL OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016566588<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Egli, M.]]		[[Category: Egli, M.]]
	[[Category: Li, F.]]		[[Category: Li, F.]]

OCA: Protected "2fil" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 15:04:40 GMT

Protected "2fil" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:04, 14 August 2012

OCA at 15:04, 14 August 2012

OCA — Tue, 14 Aug 2012 15:04:39 GMT

←Older revision		Revision as of 15:04, 14 August 2012
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	[[Image:2fil.png\|left\|200px]]		[[Image:2fil.png\|left\|200px]]

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	===Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)===		===Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)===

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	{{ABSTRACT_PUBMED_16566588}}		{{ABSTRACT_PUBMED_16566588}}

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA].	+	[[2fil]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIL OCA].

	==Reference==		==Reference==
-	2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H., Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M, Biochemistry. 2006 Apr 4;45(13):4141-52. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~16566588 16566588]~~	+	<ref group="xtra">PMID:016566588</ref><references group="xtra"/>
	[[Category: Egli, M.]]		[[Category: Egli, M.]]
	[[Category: Li, F.]]		[[Category: Li, F.]]
	[[Category: 2'-fluoroarabino acid]]		[[Category: 2'-fluoroarabino acid]]
	[[Category: A-form dna]]		[[Category: A-form dna]]
		+	[[Category: Dna]]
	[[Category: Sugar modification]]		[[Category: Sugar modification]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:44:42 2008''