2fn0 - Revision history

OCA at 09:29, 30 August 2023

OCA — Wed, 30 Aug 2023 09:29:24 GMT

←Older revision		Revision as of 09:29, 30 August 2023
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	<StructureSection load='2fn0' size='340' side='right'caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2fn0' size='340' side='right'caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_enterocoliticum"_schleifstein_and_coleman_1939 "bacterium enterocoliticum" schleifstein and coleman 1939~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2fn1\|2fn1]]~~</~~div~~><~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">IRP9 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 "Bacterium enterocoliticum" Schleifstein and Coleman 1939])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [https://pdbe.org/2fn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [https://www.ebi.ac.uk/pdbsum/2fn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [https://pdbe.org/2fn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [https://www.ebi.ac.uk/pdbsum/2fn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9X9I8_YEREN Q9X9I8_YEREN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacterium enterocoliticum schleifstein and coleman 1939]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Abell, C]]
-	[[Category: Blundell, T L]]
-	[[Category: Chirgadze, D Y]]
-	[[Category: Kerbarh, O]]
-	[[Category: Irp9]]
-	[[Category: Salicylate synthase]]
-	[[Category: Siderophore]]
-	[[Category: Transcription]]
	[[Category: Yersinia enterocolitica]]		[[Category: Yersinia enterocolitica]]
		+	[[Category: Abell C]]
		+	[[Category: Blundell TL]]
		+	[[Category: Chirgadze DY]]
		+	[[Category: Kerbarh O]]

OCA at 15:29, 3 March 2021

OCA — Wed, 03 Mar 2021 15:29:47 GMT

←Older revision		Revision as of 15:29, 3 March 2021
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	==Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)==		==Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)==
-	<StructureSection load='2fn0' size='340' side='right' caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='2fn0' size='340' side='right'caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_enterocoliticum"_schleifstein_and_coleman_1939 "bacterium enterocoliticum" schleifstein and coleman 1939]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_enterocoliticum"_schleifstein_and_coleman_1939 "bacterium enterocoliticum" schleifstein and coleman 1939]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fn1\|2fn1]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 "Bacterium enterocoliticum" Schleifstein and Coleman 1939])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 "Bacterium enterocoliticum" Schleifstein and Coleman 1939])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [~~http~~://pdbe.org/2fn0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2fn0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [https://pdbe.org/2fn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [https://www.ebi.ac.uk/pdbsum/2fn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/2fn0_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/2fn0_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacterium enterocoliticum schleifstein and coleman 1939]]		[[Category: Bacterium enterocoliticum schleifstein and coleman 1939]]
		+	[[Category: Large Structures]]
	[[Category: Abell, C]]		[[Category: Abell, C]]
	[[Category: Blundell, T L]]		[[Category: Blundell, T L]]

OCA at 07:41, 18 October 2017

OCA — Wed, 18 Oct 2017 07:41:06 GMT

←Older revision		Revision as of 07:41, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)==		==Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)==
	<StructureSection load='2fn0' size='340' side='right' caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2fn0' size='340' side='right' caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 "Bacterium enterocoliticum" Schleifstein and Coleman 1939])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 "Bacterium enterocoliticum" Schleifstein and Coleman 1939])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [http://pdbe.org/2fn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/2fn0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [http://pdbe.org/2fn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/2fn0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn0 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 19:28, 7 February 2016

OCA — Sun, 07 Feb 2016 19:28:24 GMT

←Older revision		Revision as of 19:28, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fn0 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 04:22, 10 September 2015

OCA — Thu, 10 Sep 2015 04:22:21 GMT

←Older revision		Revision as of 04:22, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2fn0' size='340' side='right' caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2fn0' size='340' side='right' caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Yersinia_enterocolitica Yersinia enterocolitica~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_enterocoliticum"_schleifstein_and_coleman_1939 "bacterium enterocoliticum" schleifstein and coleman 1939]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 ~~Yersinia enterocolitica~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 "Bacterium enterocoliticum" Schleifstein and Coleman 1939])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/2fn0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [http://pdbe.org/2fn0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/2fn0 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2fn0" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Yersinia enterocolitica~~]]	+	[[Category: Bacterium enterocoliticum schleifstein and coleman 1939]]
	[[Category: Abell, C]]		[[Category: Abell, C]]
	[[Category: Blundell, T L]]		[[Category: Blundell, T L]]
Line 39:		Line 40:
	[[Category: Siderophore]]		[[Category: Siderophore]]
	[[Category: Transcription]]		[[Category: Transcription]]
		+	[[Category: Yersinia enterocolitica]]

OCA at 08:34, 16 January 2015

OCA — Fri, 16 Jan 2015 08:34:11 GMT

←Older revision		Revision as of 08:34, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 Yersinia enterocolitica])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 Yersinia enterocolitica])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/2fn0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/2fn0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Yersinia enterocolitica]]		[[Category: Yersinia enterocolitica]]
-	[[Category: Abell, C.]]	+	[[Category: Abell, C]]
-	[[Category: Blundell, T L.]]	+	[[Category: Blundell, T L]]
-	[[Category: Chirgadze, D Y.]]	+	[[Category: Chirgadze, D Y]]
-	[[Category: Kerbarh, O.]]	+	[[Category: Kerbarh, O]]
	[[Category: Irp9]]		[[Category: Irp9]]
	[[Category: Salicylate synthase]]		[[Category: Salicylate synthase]]
	[[Category: Siderophore]]		[[Category: Siderophore]]
	[[Category: Transcription]]		[[Category: Transcription]]
-	[[Category: Yersinia enterocolitica]]

OCA at 08:13, 30 September 2014

OCA — Tue, 30 Sep 2014 08:13:02 GMT

←Older revision		Revision as of 08:13, 30 September 2014
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-	[[~~Image:~~2fn0.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)==
		+	<StructureSection load='2fn0' size='340' side='right' caption='[[2fn0]], [[Resolution\|resolution]] 1.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2fn0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FN0 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fn1\|2fn1]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IRP9 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=630 Yersinia enterocolitica])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fn0 RCSB], [http://www.ebi.ac.uk/pdbsum/2fn0 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/2fn0_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The salicylate synthase, Irp9, from Yersinia enterocolitica is involved in the biosynthesis of the siderophore yersiniabactin. It is a bifunctional enzyme that forms salicylate and pyruvate from chorismate and water via the intermediate isochorismate. Here we report the first crystal structure of Irp9 and also of its complex with the reaction products salicylate and pyruvate at 1.85 A and 2.1 A resolution, respectively. Like other members of the chorismate-utilizing enzyme family, e.g. the TrpE subunit of anthranilate synthase and the PabB subunit of 4-amino-4-deoxychorismate synthase, Irp9 has a complex alpha/beta fold. The crystal structure of Irp9 contains one molecule each of phosphate and acetate derived from the crystallization buffer. The Irp9-products complex structure was obtained by soaking chorismate into Irp9, demonstrating that the enzyme is still catalytically active in the crystal. Both structures contain Mg(2+) in the active site. There is no evidence of the allosteric tryptophan binding site found in TrpE and PabB. Mutagenesis of Glu240, His321 and Tyr372 provided some insight into the mechanism of the two transformations catalyzed by Irp9. Knowledge of the structure of Irp9 will guide the search for potent inhibitors of salicylate formation, and hence of bacterial iron uptake, which is directly related to the virulence of Yersinia.

-	~~{{STRUCTURE_2fn0\| PDB=2fn0 \| SCENE= }}~~	+	Crystal structures of Yersinia enterocolitica salicylate synthase and its complex with the reaction products salicylate and pyruvate.,Kerbarh O, Chirgadze DY, Blundell TL, Abell C J Mol Biol. 2006 Mar 24;357(2):524-34. Epub 2006 Jan 11. PMID:16434053<ref>PMID:16434053</ref>

-	~~===Crystal structure~~ of ~~Yersinia enterocolitica salicylate synthase (Irp9)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16434053}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2fn0]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:016434053<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Yersinia enterocolitica]]		[[Category: Yersinia enterocolitica]]
	[[Category: Abell, C.]]		[[Category: Abell, C.]]

OCA: Protected "2fn0" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 10:39:56 GMT

Protected "2fn0" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:39, 7 January 2013

OCA at 10:39, 7 January 2013

OCA — Mon, 07 Jan 2013 10:39:53 GMT

←Older revision		Revision as of 10:39, 7 January 2013
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-	{{Seed}}
	[[Image:2fn0.png\|left\|200px]]		[[Image:2fn0.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2fn0", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2fn0\| PDB=2fn0 \| SCENE= }}		{{STRUCTURE_2fn0\| PDB=2fn0 \| SCENE= }}

	===Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)===		===Crystal structure of Yersinia enterocolitica salicylate synthase (Irp9)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16434053}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16434053 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16434053}}		{{ABSTRACT_PUBMED_16434053}}

	==About this Structure==		==About this Structure==
-	~~2FN0~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA].	+	[[2fn0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16434053~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016434053</ref><references group="xtra"/>
	[[Category: Yersinia enterocolitica]]		[[Category: Yersinia enterocolitica]]
	[[Category: Abell, C.]]		[[Category: Abell, C.]]
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	[[Category: Salicylate synthase]]		[[Category: Salicylate synthase]]
	[[Category: Siderophore]]		[[Category: Siderophore]]
		+	[[Category: Transcription]]
	[[Category: Yersinia enterocolitica]]		[[Category: Yersinia enterocolitica]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:01:31 2009''

OCA at 14:01, 16 February 2009

OCA — Mon, 16 Feb 2009 14:01:33 GMT

←Older revision		Revision as of 14:01, 16 February 2009
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	==About this Structure==		==About this Structure==
-	2FN0 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA].	+	2FN0 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN0 OCA].

	==Reference==		==Reference==
-	Crystal structures of Yersinia enterocolitica salicylate synthase and its complex with the reaction products salicylate and pyruvate., Kerbarh O, Chirgadze DY, Blundell TL, Abell C, J Mol Biol. 2006 Mar 24;357(2):524-34. Epub 2006 Jan 11. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16434053 16434053]~~	+	<ref group="xtra">PMID:16434053</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Yersinia enterocolitica]]		[[Category: Yersinia enterocolitica]]
	[[Category: Abell, C.]]		[[Category: Abell, C.]]
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	[[Category: Yersinia enterocolitica]]		[[Category: Yersinia enterocolitica]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 19~~:05:~~02 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:01:31 2009''