2fqc - Revision history

OCA at 12:37, 10 January 2024

OCA — Wed, 10 Jan 2024 12:37:21 GMT

←Older revision		Revision as of 12:37, 10 January 2024
Line 1:		Line 1:

	==Solution structure of conotoxin pl14a==		==Solution structure of conotoxin pl14a==
-	<StructureSection load='2fqc' size='340' side='right'caption='[[2fqc~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2fqc' size='340' side='right'caption='[[2fqc]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FQC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Conus_planorbis Conus planorbis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FQC FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [https://pdbe.org/2fqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [https://www.ebi.ac.uk/pdbsum/2fqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [https://pdbe.org/2fqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [https://www.ebi.ac.uk/pdbsum/2fqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqc ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CJEA_CONPO CJEA_CONPO]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Conus planorbis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Craik~~, D J~~]]	+	[[Category: Craik DJ]]
-	[[Category: Daly~~, N L]]~~	+	[[Category: Daly NL]]
-	~~[[Category: Alpha-helix]]~~	+
-	~~[[Category: Disulfide bond]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 10:54, 6 April 2022

OCA — Wed, 06 Apr 2022 10:54:28 GMT

←Older revision		Revision as of 10:54, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='2fqc' size='340' side='right'caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2fqc' size='340' side='right'caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2FQC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FQC FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [~~http~~://pdbe.org/2fqc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2fqc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [https://pdbe.org/2fqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [https://www.ebi.ac.uk/pdbsum/2fqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:37, 25 June 2020

OCA — Thu, 25 Jun 2020 06:37:51 GMT

←Older revision		Revision as of 06:37, 25 June 2020
Line 3:		Line 3:
	<StructureSection load='2fqc' size='340' side='right'caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2fqc' size='340' side='right'caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FQC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2FQC FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [http://pdbe.org/2fqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [http://www.ebi.ac.uk/pdbsum/2fqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [http://pdbe.org/2fqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [http://www.ebi.ac.uk/pdbsum/2fqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:52, 18 March 2020

OCA — Wed, 18 Mar 2020 10:52:50 GMT

←Older revision		Revision as of 10:52, 18 March 2020
Line 1:		Line 1:

	==Solution structure of conotoxin pl14a==		==Solution structure of conotoxin pl14a==
-	<StructureSection load='2fqc' size='340' side='right' caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2fqc' size='340' side='right'caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQC FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Craik, D J]]		[[Category: Craik, D J]]
	[[Category: Daly, N L]]		[[Category: Daly, N L]]

OCA at 09:26, 14 June 2018

OCA — Thu, 14 Jun 2018 09:26:48 GMT

←Older revision		Revision as of 09:26, 14 June 2018
Line 1:		Line 1:
		+
	==Solution structure of conotoxin pl14a==		==Solution structure of conotoxin pl14a==
	<StructureSection load='2fqc' size='340' side='right' caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2fqc' size='340' side='right' caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQC FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [http://pdbe.org/2fqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [http://www.ebi.ac.uk/pdbsum/2fqc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [http://pdbe.org/2fqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [http://www.ebi.ac.uk/pdbsum/2fqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fqc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:32, 11 September 2015

OCA — Fri, 11 Sep 2015 23:32:47 GMT

←Older revision		Revision as of 23:32, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQC FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [http://www.ebi.ac.uk/pdbsum/2fqc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [http://pdbe.org/2fqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [http://www.ebi.ac.uk/pdbsum/2fqc PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2fqc" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:33, 16 January 2015

OCA — Fri, 16 Jan 2015 09:33:50 GMT

←Older revision		Revision as of 09:33, 16 January 2015
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Craik, D J.]]	+	[[Category: Craik, D J]]
-	[[Category: Daly, N L.]]	+	[[Category: Daly, N L]]
	[[Category: Alpha-helix]]		[[Category: Alpha-helix]]
	[[Category: Disulfide bond]]		[[Category: Disulfide bond]]
	[[Category: Toxin]]		[[Category: Toxin]]

OCA at 15:40, 12 October 2014

OCA — Sun, 12 Oct 2014 15:40:41 GMT

←Older revision		Revision as of 15:40, 12 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2fqc.~~png~~\|~~left\|200px~~]]	+	==Solution structure of conotoxin pl14a==
		+	<StructureSection load='2fqc' size='340' side='right' caption='[[2fqc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FQC FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fqc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fqc RCSB], [http://www.ebi.ac.uk/pdbsum/2fqc PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Using assay-directed fractionation of the venom from the vermivorous cone snail Conus planorbis, we isolated a new conotoxin, designated pl14a, with potent activity at both nicotinic acetylcholine receptors and a voltage-gated potassium channel subtype. pl14a contains 25 amino acid residues with an amidated C-terminus, an elongated N-terminal tail (six residues), and two disulfide bonds (1-3, 2-4 connectivity) in a novel framework distinct from other conotoxins. The peptide was chemically synthesized, and its three-dimensional structure was demonstrated to be well-defined, with an alpha-helix and two 3(10)-helices present. Analysis of a cDNA clone encoding the prepropeptide precursor of pl14a revealed a novel signal sequence, indicating that pl14a belongs to a new gene superfamily, the J-conotoxin superfamily. Five additional peptides in the J-superfamily were identified. Intracranial injection of pl14a in mice elicited excitatory symptoms that included shaking, rapid circling, barrel rolling, and seizures. Using the oocyte heterologous expression system, pl14a was shown to inhibit both a K+ channel subtype (Kv1.6, IC50 = 1.59 microM) and neuronal (IC50 = 8.7 microM for alpha3beta4) and neuromuscular (IC50 = 0.54 microM for alpha1beta1 epsilondelta) subtypes of the nicotinic acetylcholine receptor (nAChR). Similarities in sequence and structure are apparent between the middle loop of pl14a and the second loop of a number of alpha-conotoxins. This is the first conotoxin shown to affect the activity of both voltage-gated and ligand-gated ion channels.

-	~~{{STRUCTURE_2fqc\| PDB=2fqc \| SCENE= }}~~	+	A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.,Imperial JS, Bansal PS, Alewood PF, Daly NL, Craik DJ, Sporning A, Terlau H, Lopez-Vera E, Bandyopadhyay PK, Olivera BM Biochemistry. 2006 Jul 11;45(27):8331-40. PMID:16819832<ref>PMID:16819832</ref>

-	~~===Solution structure~~ of ~~conotoxin pl14a===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16819832}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[2fqc]] is a 1 chain structure. Full experimental information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA].~~	+	</StructureSection>
	[[Category: Craik, D J.]]		[[Category: Craik, D J.]]
	[[Category: Daly, N L.]]		[[Category: Daly, N L.]]

OCA: Protected "2fqc" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 12:46:35 GMT

Protected "2fqc" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:46, 7 January 2013

OCA at 12:46, 7 January 2013

OCA — Mon, 07 Jan 2013 12:46:33 GMT

←Older revision		Revision as of 12:46, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2fqc.png\|left\|200px]]		[[Image:2fqc.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2fqc\| PDB=2fqc \| SCENE= }}		{{STRUCTURE_2fqc\| PDB=2fqc \| SCENE= }}

	===Solution structure of conotoxin pl14a===		===Solution structure of conotoxin pl14a===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16819832}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16819832 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16819832}}		{{ABSTRACT_PUBMED_16819832}}

	==About this Structure==		==About this Structure==
-	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA].	+	[[2fqc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQC OCA].
-		+
-	~~==Reference==~~	+
-	A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins., Imperial JS, Bansal PS, Alewood PF, Daly NL, Craik DJ, Sporning A, Terlau H, Lopez-Vera E, Bandyopadhyay PK, Olivera BM, Biochemistry. 2006 Jul 11;45(27):8331-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16819832 16819832]	+
	[[Category: Craik, D J.]]		[[Category: Craik, D J.]]
	[[Category: Daly, N L.]]		[[Category: Daly, N L.]]
	[[Category: Alpha-helix]]		[[Category: Alpha-helix]]
	[[Category: Disulfide bond]]		[[Category: Disulfide bond]]
-		+	[[Category: Toxin]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Jul 29 13:39:18 2008''~~	+