2fwl - Revision history

OCA at 14:37, 29 December 2021

OCA — Wed, 29 Dec 2021 14:37:52 GMT

←Older revision		Revision as of 14:37, 29 December 2021
Line 3:		Line 3:
	<StructureSection load='2fwl' size='340' side='right'caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>		<StructureSection load='2fwl' size='340' side='right'caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Thet8 Thet8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2FWL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FWL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ehk\|1ehk]], [[1dt1\|1dt1]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [~~http~~://pdbe.org/2fwl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2fwl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2fwl ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [https://pdbe.org/2fwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [https://www.ebi.ac.uk/pdbsum/2fwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fwl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CY552_THETH CY552_THETH]] This monoheme basic protein appears to function as an electron donor to cytochrome oxidase in T.thermophilus. [[~~http~~://www.uniprot.org/uniprot/COX2_THETH COX2_THETH]] Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).	+	[[https://www.uniprot.org/uniprot/CY552_THETH CY552_THETH]] This monoheme basic protein appears to function as an electron donor to cytochrome oxidase in T.thermophilus. [[https://www.uniprot.org/uniprot/COX2_THETH COX2_THETH]] Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:

	==See Also==		==See Also==
		+	*[[Cytochrome c nitrite reductase\|Cytochrome c nitrite reductase]]
	*[[Cytochrome c oxidase 3D structures\|Cytochrome c oxidase 3D structures]]		*[[Cytochrome c oxidase 3D structures\|Cytochrome c oxidase 3D structures]]
-	*[[Nitrite reductase 3D structures\|Nitrite reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:06, 27 March 2020

OCA — Fri, 27 Mar 2020 11:06:22 GMT

←Older revision		Revision as of 11:06, 27 March 2020
Line 1:		Line 1:

	==The cytochrome c552/CuA complex from Thermus thermophilus==		==The cytochrome c552/CuA complex from Thermus thermophilus==
-	<StructureSection load='2fwl' size='340' side='right' caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>	+	<StructureSection load='2fwl' size='340' side='right'caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWL FirstGlance]. <br>
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Cytochrome c oxidase\|Cytochrome c oxidase]]	+	*[[Cytochrome c oxidase 3D structures\|Cytochrome c oxidase 3D structures]]
-	*[[Nitrite reductase\|Nitrite reductase]]	+	*[[Nitrite reductase 3D structures\|Nitrite reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 39:		Line 39:
	</StructureSection>		</StructureSection>
	[[Category: Cytochrome-c oxidase]]		[[Category: Cytochrome-c oxidase]]
		+	[[Category: Large Structures]]
	[[Category: Thet8]]		[[Category: Thet8]]
	[[Category: Loehr, F]]		[[Category: Loehr, F]]

OCA at 07:14, 20 June 2018

OCA — Wed, 20 Jun 2018 07:14:36 GMT

←Older revision		Revision as of 07:14, 20 June 2018
Line 1:		Line 1:
		+
	==The cytochrome c552/CuA complex from Thermus thermophilus==		==The cytochrome c552/CuA complex from Thermus thermophilus==
	<StructureSection load='2fwl' size='340' side='right' caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>		<StructureSection load='2fwl' size='340' side='right' caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [http://pdbe.org/2fwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [http://www.ebi.ac.uk/pdbsum/2fwl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [http://pdbe.org/2fwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [http://www.ebi.ac.uk/pdbsum/2fwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2fwl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/2fwl_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/2fwl_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fwl ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 32:		Line 33:
	==See Also==		==See Also==
	*[[Cytochrome c oxidase\|Cytochrome c oxidase]]		*[[Cytochrome c oxidase\|Cytochrome c oxidase]]
-	*[[~~Nitric~~ reductase\|~~Nitric~~ reductase]]	+	*[[Nitrite reductase\|Nitrite reductase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:57, 11 September 2015

OCA — Fri, 11 Sep 2015 13:57:20 GMT

←Older revision		Revision as of 13:57, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2fwl' size='340' side='right' caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>		<StructureSection load='2fwl' size='340' side='right' caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermus_thermophilus Thermus thermophilus~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [http://www.ebi.ac.uk/pdbsum/2fwl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [http://pdbe.org/2fwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [http://www.ebi.ac.uk/pdbsum/2fwl PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2fwl" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 37:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Cytochrome-c oxidase]]		[[Category: Cytochrome-c oxidase]]
-	[[Category: ~~Thermus thermophilus~~]]	+	[[Category: Thet8]]
	[[Category: Loehr, F]]		[[Category: Loehr, F]]
	[[Category: Ludwig, B]]		[[Category: Ludwig, B]]

OCA at 17:24, 25 December 2014

OCA — Thu, 25 Dec 2014 17:24:03 GMT

←Older revision		Revision as of 17:24, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWL FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [http://www.ebi.ac.uk/pdbsum/2fwl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [http://www.ebi.ac.uk/pdbsum/2fwl PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CY552_THETH CY552_THETH]] This monoheme basic protein appears to function as an electron donor to cytochrome oxidase in T.thermophilus. [[http://www.uniprot.org/uniprot/COX2_THETH COX2_THETH]] Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 38:
	[[Category: Cytochrome-c oxidase]]		[[Category: Cytochrome-c oxidase]]
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
-	[[Category: Loehr, F.]]	+	[[Category: Loehr, F]]
-	[[Category: Ludwig, B.]]	+	[[Category: Ludwig, B]]
-	[[Category: Luecke, C.]]	+	[[Category: Luecke, C]]
-	[[Category: Maneg, O.]]	+	[[Category: Maneg, O]]
-	[[Category: Mukrasch, M D.]]	+	[[Category: Mukrasch, M D]]
-	[[Category: Muresanu, L.]]	+	[[Category: Muresanu, L]]
-	[[Category: Pristovsek, P.]]	+	[[Category: Pristovsek, P]]
-	[[Category: Rueterjans, H.]]	+	[[Category: Rueterjans, H]]
	[[Category: Docking calculation]]		[[Category: Docking calculation]]
	[[Category: Electron transfer pathway]]		[[Category: Electron transfer pathway]]
	[[Category: Electron transport-oxidoreductase complex]]		[[Category: Electron transport-oxidoreductase complex]]
	[[Category: Redox protein complex]]		[[Category: Redox protein complex]]

OCA at 10:27, 3 October 2014

OCA — Fri, 03 Oct 2014 10:27:28 GMT

←Older revision		Revision as of 10:27, 3 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2fwl.~~png~~\|~~left~~\|200px]]	+	==The cytochrome c552/CuA complex from Thermus thermophilus==
		+	<StructureSection load='2fwl' size='340' side='right' caption='[[2fwl]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2FWL FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CUA:DINUCLEAR+COPPER+ION'>CUA</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ehk\|1ehk]], [[1dt1\|1dt1]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-c_oxidase Cytochrome-c oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.1 1.9.3.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2fwl RCSB], [http://www.ebi.ac.uk/pdbsum/2fwl PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fw/2fwl_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structural analysis of the redox complex between the soluble cytochrome c552 and the membrane-integral cytochrome ba3 oxidase of Thermus thermophilus is complicated by the transient nature of this protein-protein interaction. Using NMR-based chemical shift perturbation mapping, however, we identified the contact regions between cytochrome c552 and the CuA domain, the fully functional water-soluble fragment of subunit II of the ba3 oxidase. First we determined the complete backbone resonance assignments of both proteins for each redox state. Subsequently, two-dimensional [15N,1H]TROSY spectra recorded for each redox partner both in free and complexed state indicated those surface residues affected by complex formation between the two proteins. This chemical shift analysis performed for both redox states provided a topological description of the contact surface on each partner molecule. Remarkably, very pronounced indirect effects, which were observed on the back side of the heme cleft only in the reduced state, suggested that alterations of the electron distribution in the porphyrin ring due to formation of the protein-protein complex are apparently sensed even beyond the heme propionate groups. The contact residues of each redox partner, as derived from the chemical shift perturbation mapping, were employed for a protein-protein docking calculation that provided a structure ensemble of 10 closely related conformers representing the complex between cytochrome c552 and the CuA domain. Based on these structures, the electron transfer pathway from the heme of cytochrome c552 to the CuA center of the ba3 oxidase has been predicted.

-	~~{{STRUCTURE_2fwl\| PDB=2fwl \| SCENE= }}~~	+	The electron transfer complex between cytochrome c552 and the CuA domain of the Thermus thermophilus ba3 oxidase. A combined NMR and computational approach.,Muresanu L, Pristovsek P, Lohr F, Maneg O, Mukrasch MD, Ruterjans H, Ludwig B, Lucke C J Biol Chem. 2006 May 19;281(20):14503-13. Epub 2006 Mar 22. PMID:16554303<ref>PMID:16554303</ref>

-	~~===The cytochrome c552~~/~~CuA complex from Thermus thermophilus===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16554303}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2fwl]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermus_thermophilus Thermus thermophilus]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA].~~	+

	==See Also==		==See Also==
-	*[[Cytochrome c\|Cytochrome c]]
	*[[Cytochrome c oxidase\|Cytochrome c oxidase]]		*[[Cytochrome c oxidase\|Cytochrome c oxidase]]
-		+	*[[Nitric reductase\|Nitric reductase]]
-	==~~Reference~~==	+	== References ==
-	<~~ref group="xtra">PMID:016554303<~~/~~ref~~><~~references group="xtra"~~/>	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Cytochrome-c oxidase]]		[[Category: Cytochrome-c oxidase]]
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]

OCA at 19:24, 20 October 2012

OCA — Sat, 20 Oct 2012 19:24:24 GMT

←Older revision		Revision as of 19:24, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2fwl]] is a 2 chain structure ~~of [[Cytochrome c]] and [[Cytochrome c oxidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA].	+	[[2fwl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA].

	==See Also==		==See Also==

OCA: Protected "2fwl" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 07:15:22 GMT

Protected "2fwl" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:15, 27 July 2012

OCA at 07:15, 27 July 2012

OCA — Fri, 27 Jul 2012 07:15:21 GMT

←Older revision		Revision as of 07:15, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2fwl.png\|left\|200px]]		[[Image:2fwl.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2fwl", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2fwl\| PDB=2fwl \| SCENE= }}		{{STRUCTURE_2fwl\| PDB=2fwl \| SCENE= }}

	===The cytochrome c552/CuA complex from Thermus thermophilus===		===The cytochrome c552/CuA complex from Thermus thermophilus===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16554303}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16554303 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16554303}}		{{ABSTRACT_PUBMED_16554303}}

	==About this Structure==		==About this Structure==
-	~~2FWL~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA].	+	[[2fwl]] is a 2 chain structure of [[Cytochrome c]] and [[Cytochrome c oxidase]] with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA].
		+
		+	==See Also==
		+	*[[Cytochrome c\|Cytochrome c]]
		+	*[[Cytochrome c oxidase\|Cytochrome c oxidase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16554303~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016554303</ref><references group="xtra"/>
	[[Category: Cytochrome-c oxidase]]		[[Category: Cytochrome-c oxidase]]
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
Line 36:		Line 28:
	[[Category: Docking calculation]]		[[Category: Docking calculation]]
	[[Category: Electron transfer pathway]]		[[Category: Electron transfer pathway]]
		+	[[Category: Electron transport-oxidoreductase complex]]
	[[Category: Redox protein complex]]		[[Category: Redox protein complex]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:06:11 2009''

OCA at 22:06, 17 February 2009

OCA — Tue, 17 Feb 2009 22:06:12 GMT

←Older revision		Revision as of 22:06, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2FWL is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA].	+	2FWL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWL OCA].

	==Reference==		==Reference==
-	The electron transfer complex between cytochrome c552 and the CuA domain of the Thermus thermophilus ba3 oxidase. A combined NMR and computational approach., Muresanu L, Pristovsek P, Lohr F, Maneg O, Mukrasch MD, Ruterjans H, Ludwig B, Lucke C, J Biol Chem. 2006 May 19;281(20):14503-13. Epub 2006 Mar 22. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16554303 16554303]~~	+	<ref group="xtra">PMID:16554303</ref><references group="xtra"/>
	[[Category: Cytochrome-c oxidase]]		[[Category: Cytochrome-c oxidase]]
-	[[Category: Protein complex]]
	[[Category: Thermus thermophilus]]		[[Category: Thermus thermophilus]]
	[[Category: Loehr, F.]]		[[Category: Loehr, F.]]
Line 39:		Line 38:
	[[Category: Redox protein complex]]		[[Category: Redox protein complex]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 07:25~~:06 ~~2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:06:11 2009''