2g6d - Revision history

OCA at 09:57, 5 May 2021

OCA — Wed, 05 May 2021 09:57:23 GMT

←Older revision		Revision as of 09:57, 5 May 2021
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	<StructureSection load='2g6d' size='340' side='right'caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2g6d' size='340' side='right'caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2G6D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G6D FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [~~http~~://pdbe.org/2g6d PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2g6d PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2g6d ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [https://pdbe.org/2g6d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [https://www.ebi.ac.uk/pdbsum/2g6d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g6d ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.	+	[[https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:38, 24 July 2019

OCA — Wed, 24 Jul 2019 09:38:08 GMT

←Older revision		Revision as of 09:38, 24 July 2019
Line 1:		Line 1:

	==Human cathepsin S mutant with vinyl sulfone inhibitor CRA-14009==		==Human cathepsin S mutant with vinyl sulfone inhibitor CRA-14009==
-	<StructureSection load='2g6d' size='340' side='right' caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2g6d' size='340' side='right'caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G6D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G6D FirstGlance]. <br>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/2g6d_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/2g6d_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 20:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g6d ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g6d ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+
		+	==See Also==
		+	*[[Cathepsin 3D structures\|Cathepsin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Cathepsin S]]		[[Category: Cathepsin S]]
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Somoza, J R]]		[[Category: Somoza, J R]]
	[[Category: Cysteine protease]]		[[Category: Cysteine protease]]

OCA at 07:48, 18 October 2017

OCA — Wed, 18 Oct 2017 07:48:35 GMT

←Older revision		Revision as of 07:48, 18 October 2017
Line 1:		Line 1:
		+
	==Human cathepsin S mutant with vinyl sulfone inhibitor CRA-14009==		==Human cathepsin S mutant with vinyl sulfone inhibitor CRA-14009==
	<StructureSection load='2g6d' size='340' side='right' caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2g6d' size='340' side='right' caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [http://pdbe.org/2g6d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [http://www.ebi.ac.uk/pdbsum/2g6d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [http://pdbe.org/2g6d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [http://www.ebi.ac.uk/pdbsum/2g6d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2g6d ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g6d ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g6d ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-
-	==See Also==
-	*[[Cathepsin\|Cathepsin]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:18, 8 February 2016

OCA — Mon, 08 Feb 2016 12:18:19 GMT

←Older revision		Revision as of 12:18, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g6d ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

OCA at 11:29, 10 September 2015

OCA — Thu, 10 Sep 2015 11:29:54 GMT

←Older revision		Revision as of 11:29, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2g6d' size='340' side='right' caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2g6d' size='340' side='right' caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G6D FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G6D FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [http://www.ebi.ac.uk/pdbsum/2g6d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [http://pdbe.org/2g6d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [http://www.ebi.ac.uk/pdbsum/2g6d PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Cathepsin S]]		[[Category: Cathepsin S]]
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Somoza, J R]]		[[Category: Somoza, J R]]
	[[Category: Cysteine protease]]		[[Category: Cysteine protease]]

OCA at 23:15, 24 December 2014

OCA — Wed, 24 Dec 2014 23:15:42 GMT

←Older revision		Revision as of 23:15, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G6D FirstGlance]. <br>		<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G6D FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [http://www.ebi.ac.uk/pdbsum/2g6d PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [http://www.ebi.ac.uk/pdbsum/2g6d PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 26:
	[[Category: Cathepsin S]]		[[Category: Cathepsin S]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Somoza, J R~~.]]~~	+	[[Category: Somoza, J R]]
-	~~[[Category: 14009~~]]	+
	[[Category: Cysteine protease]]		[[Category: Cysteine protease]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Papain]]		[[Category: Papain]]
	[[Category: Proteinase]]		[[Category: Proteinase]]

OCA at 03:16, 29 September 2014

OCA — Mon, 29 Sep 2014 03:16:12 GMT

←Older revision		Revision as of 03:16, 29 September 2014
Line 1:		Line 1:
-	~~[[Image:2g6d.png\|left\|200px]]~~	+	==Human cathepsin S mutant with vinyl sulfone inhibitor CRA-14009==
-		+	<StructureSection load='2g6d' size='340' side='right' caption='[[2g6d]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{STRUCTURE_2g6d\| PDB=2g6d \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G6D FirstGlance]. <br>
-	===Human cathepsin S mutant with vinyl sulfone inhibitor CRA-14009===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQQ:N-[(1S)-1-[({(1S)-3-PHENYL-1-[2-(PHENYLSULFONYL)ETHYL]PROPYL}AMINO)CARBONYL]-3-(PHENYLSULFONYL)PROPYL]MORPHOLINE-4-CARBOXAMIDE'>MQQ</scene><br>
-		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
-		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g6d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2g6d RCSB], [http://www.ebi.ac.uk/pdbsum/2g6d PDBsum]</span></td></tr>
-	==~~About this Structure~~==	+	<table>
-	[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA].	+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g6/2g6d_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Cathepsin\|Cathepsin]]		*[[Cathepsin\|Cathepsin]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Cathepsin S]]		[[Category: Cathepsin S]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]

OCA at 10:06, 20 October 2012

OCA — Sat, 20 Oct 2012 10:06:43 GMT

←Older revision		Revision as of 10:06, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[2g6d]] is a 1 chain structure ~~of [[Cathepsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA].	+	[[2g6d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G6D OCA].

	==See Also==		==See Also==

OCA at 01:01, 26 July 2012

OCA — Thu, 26 Jul 2012 01:01:01 GMT

←Older revision		Revision as of 01:01, 26 July 2012
Line 1:		Line 1:
	[[Image:2g6d.png\|left\|200px]]		[[Image:2g6d.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2g6d", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2g6d\| PDB=2g6d \| SCENE= }}		{{STRUCTURE_2g6d\| PDB=2g6d \| SCENE= }}

Line 16:		Line 10:

	==See Also==		==See Also==
-	*[[Cathepsin]]	+	*[[Cathepsin\|Cathepsin]]
	[[Category: Cathepsin S]]		[[Category: Cathepsin S]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]

OCA: Protected "2g6d" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 20:45:38 GMT

Protected "2g6d" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:45, 26 December 2010