2gbb - Revision history

OCA at 18:55, 10 March 2021

OCA — Wed, 10 Mar 2021 18:55:07 GMT

←Older revision		Revision as of 18:55, 10 March 2021
Line 1:		Line 1:

	==Crystal structure of secreted chorismate mutase from Yersinia pestis==		==Crystal structure of secreted chorismate mutase from Yersinia pestis==
-	<StructureSection load='2gbb' size='340' side='right' caption='[[2gbb]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='2gbb' size='340' side='right'caption='[[2gbb]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2gbb]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Yersinia_pestis_biovar_mediaevails_str._91001 Yersinia pestis biovar mediaevails str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2GBB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2gbb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_biovar_mediaevails_str._91001 Yersinia pestis biovar mediaevails str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GBB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Mediaevails str. 91001])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Mediaevails str. 91001])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [~~http~~://pdbe.org/2gbb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2gbb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2gbb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [https://pdbe.org/2gbb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [https://www.ebi.ac.uk/pdbsum/2gbb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gbb ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/2gbb_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/2gbb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
		+	[[Category: Large Structures]]
	[[Category: Yersinia pestis biovar mediaevails str. 91001]]		[[Category: Yersinia pestis biovar mediaevails str. 91001]]
	[[Category: Kim, S K]]		[[Category: Kim, S K]]

OCA at 07:50, 18 October 2017

OCA — Wed, 18 Oct 2017 07:50:26 GMT

←Older revision		Revision as of 07:50, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of secreted chorismate mutase from Yersinia pestis==		==Crystal structure of secreted chorismate mutase from Yersinia pestis==
	<StructureSection load='2gbb' size='340' side='right' caption='[[2gbb]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2gbb' size='340' side='right' caption='[[2gbb]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Mediaevails str. 91001])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Mediaevails str. 91001])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [http://pdbe.org/2gbb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [http://www.ebi.ac.uk/pdbsum/2gbb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [http://pdbe.org/2gbb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [http://www.ebi.ac.uk/pdbsum/2gbb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2gbb ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 15:02, 7 February 2016

OCA — Sun, 07 Feb 2016 15:02:32 GMT

←Older revision		Revision as of 15:02, 7 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gbb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:37, 10 September 2015

OCA — Thu, 10 Sep 2015 02:37:02 GMT

←Older revision		Revision as of 02:37, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2gbb' size='340' side='right' caption='[[2gbb]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2gbb' size='340' side='right' caption='[[2gbb]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2gbb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Yersinia_pestis_biovar_microtus_str~~._91001 Yersinia pestis biovar ~~microtus~~ str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GBB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2gbb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_mediaevails_str._91001 Yersinia pestis biovar mediaevails str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GBB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar ~~Microtus~~ str. 91001])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Mediaevails str. 91001])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [http://www.ebi.ac.uk/pdbsum/2gbb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [http://pdbe.org/2gbb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [http://www.ebi.ac.uk/pdbsum/2gbb PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2gbb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
-	[[Category: Yersinia pestis biovar ~~microtus~~ str. 91001]]	+	[[Category: Yersinia pestis biovar mediaevails str. 91001]]
	[[Category: Kim, S K]]		[[Category: Kim, S K]]
	[[Category: Ladner, J E]]		[[Category: Ladner, J E]]

OCA at 08:20, 16 January 2015

OCA — Fri, 16 Jan 2015 08:20:18 GMT

←Older revision		Revision as of 08:20, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2gbb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GBB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2gbb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GBB FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Microtus str. 91001])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Microtus str. 91001])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [http://www.ebi.ac.uk/pdbsum/2gbb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [http://www.ebi.ac.uk/pdbsum/2gbb PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
	[[Category: Yersinia pestis biovar microtus str. 91001]]		[[Category: Yersinia pestis biovar microtus str. 91001]]
-	[[Category: Kim, S K.]]	+	[[Category: Kim, S K]]
-	[[Category: Ladner, J E.]]	+	[[Category: Ladner, J E]]
-	[[Category: Nelson, B C.]]	+	[[Category: Nelson, B C]]
-	[[Category: Reddy, P T.]]	+	[[Category: Reddy, P T]]
-	[[Category: Robinson, H.]]	+	[[Category: Robinson, H]]
	[[Category: Alpha helical bundle]]		[[Category: Alpha helical bundle]]
	[[Category: Isomerase]]		[[Category: Isomerase]]

OCA at 09:31, 30 September 2014

OCA — Tue, 30 Sep 2014 09:31:56 GMT

←Older revision		Revision as of 09:31, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2gbb.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of secreted chorismate mutase from Yersinia pestis==
		+	<StructureSection load='2gbb' size='340' side='right' caption='[[2gbb]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2gbb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GBB FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">y2828 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=229193 Yersinia pestis biovar Microtus str. 91001])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chorismate_mutase Chorismate mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.5 5.4.99.5] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gbb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gbb RCSB], [http://www.ebi.ac.uk/pdbsum/2gbb PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/2gbb_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Rv0948c gene from Mycobacterium tuberculosis H(37)R(v) encodes a 90 amino acid protein as the natural gene product with chorismate mutase (CM) activity. The protein, 90-MtCM, exhibits Michaelis-Menten kinetics with a k(cat) of 5.5+/-0.2s(-1) and a K(m) of 1500+/-100microm at 37 degrees C and pH7.5. The 2.0A X-ray structure shows that 90-MtCM is an all alpha-helical homodimer (Protein Data Bank ID: 2QBV) with the topology of Escherichia coli CM (EcCM), and that both protomers contribute to each catalytic site. Superimposition onto the structure of EcCM and the sequence alignment shows that the C-terminus helix3 is shortened. The absence of two residues in the active site of 90-MtCM corresponding to Ser84 and Gln88 of EcCM appears to be one reason for the low k(cat). Hence, 90-MtCM belongs to a subfamily of alpha-helical AroQ CMs termed AroQ(delta.) The CM gene (y2828) from Yersinia pestis encodes a 186 amino acid protein with an N-terminal signal peptide that directs the protein to the periplasm. The mature protein, YpCM, exhibits Michaelis-Menten kinetics with a k(cat) of 70+/-5s(-1) and K(m) of 500+/-50microm at 37 degrees C and pH7.5. The 2.1A X-ray structure shows that YpCM is an all alpha-helical protein, and functions as a homodimer, and that each protomer has an independent catalytic unit (Protein Data Bank ID: 2GBB). YpCM belongs to the AroQ(gamma) class of CMs, and is similar to the secreted CM (Rv1885c, MtCM) from M.tuberculosis.

-	~~{{STRUCTURE_2gbb\| PDB=2gbb \| SCENE= }}~~	+	A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H(37)R(v) and the secreted chorismate mutase (y2828) from Yersinia pestis.,Kim SK, Reddy SK, Nelson BC, Robinson H, Reddy PT, Ladner JE FEBS J. 2008 Oct;275(19):4824-35. Epub 2008 Aug 22. PMID:18727669<ref>PMID:18727669</ref>

-	~~===Crystal structure~~ of ~~secreted chorismate mutase from Yersinia pestis===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18727669}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2gbb]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Yersinia_pestis_biovar_microtus_str~~.~~_91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:018727669<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
	[[Category: Yersinia pestis biovar microtus str. 91001]]		[[Category: Yersinia pestis biovar microtus str. 91001]]

OCA: Protected "2gbb" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 14:25:50 GMT

Protected "2gbb" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:25, 7 January 2013

OCA at 14:25, 7 January 2013

OCA — Mon, 07 Jan 2013 14:25:46 GMT

←Older revision		Revision as of 14:25, 7 January 2013
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-	{{Seed}}
	[[Image:2gbb.png\|left\|200px]]		[[Image:2gbb.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2gbb", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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	{{STRUCTURE_2gbb\| PDB=2gbb \| SCENE= }}		{{STRUCTURE_2gbb\| PDB=2gbb \| SCENE= }}

	===Crystal structure of secreted chorismate mutase from Yersinia pestis===		===Crystal structure of secreted chorismate mutase from Yersinia pestis===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18727669}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18727669 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_18727669}}		{{ABSTRACT_PUBMED_18727669}}

	==About this Structure==		==About this Structure==
-	~~2GBB~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA].	+	[[2gbb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18727669~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018727669</ref><references group="xtra"/>
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
	[[Category: Yersinia pestis biovar microtus str. 91001]]		[[Category: Yersinia pestis biovar microtus str. 91001]]
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	[[Category: Alpha helical bundle]]		[[Category: Alpha helical bundle]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:03:28 2010''

OCA at 07:03, 17 March 2010

OCA — Wed, 17 Mar 2010 07:03:28 GMT

←Older revision		Revision as of 07:03, 17 March 2010
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	===Crystal structure of secreted chorismate mutase from Yersinia pestis===		===Crystal structure of secreted chorismate mutase from Yersinia pestis===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_18727669}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 18727669 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_18727669}}

	==About this Structure==		==About this Structure==
-	2GBB is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA].	+	2GBB is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:18727669</ref><references group="xtra"/>
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
	[[Category: Yersinia pestis biovar microtus str. 91001]]		[[Category: Yersinia pestis biovar microtus str. 91001]]
Line 23:		Line 32:
	[[Category: Robinson, H.]]		[[Category: Robinson, H.]]
	[[Category: Alpha helical bundle]]		[[Category: Alpha helical bundle]]
		+	[[Category: Isomerase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Feb 16 14~~:38:~~52 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 17 09:03:28 2010''

OCA at 12:38, 16 February 2009

OCA — Mon, 16 Feb 2009 12:38:52 GMT

←Older revision		Revision as of 12:38, 16 February 2009
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-	[[Image:2gbb.~~jpg~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:2gbb.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_2gbb\| PDB=2gbb \| SCENE= }}		{{STRUCTURE_2gbb\| PDB=2gbb \| SCENE= }}

-	~~'''~~Crystal structure of secreted chorismate mutase from Yersinia pestis~~'''~~	+	===Crystal structure of secreted chorismate mutase from Yersinia pestis===


	==About this Structure==		==About this Structure==
-	2GBB is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA].	+	2GBB is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Yersinia_pestis_biovar_microtus_str._91001 Yersinia pestis biovar microtus str. 91001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBB OCA].
	[[Category: Chorismate mutase]]		[[Category: Chorismate mutase]]
-	[[Category: Single protein]]
	[[Category: Yersinia pestis biovar microtus str. 91001]]		[[Category: Yersinia pestis biovar microtus str. 91001]]
	[[Category: Kim, S K.]]		[[Category: Kim, S K.]]
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	[[Category: Robinson, H.]]		[[Category: Robinson, H.]]
	[[Category: Alpha helical bundle]]		[[Category: Alpha helical bundle]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 04~~:54:~~48 2008~~''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:38:52 2009''