2h1y - Revision history

OCA at 08:50, 25 October 2023

OCA — Wed, 25 Oct 2023 08:50:07 GMT

←Older revision		Revision as of 08:50, 25 October 2023
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	<StructureSection load='2h1y' size='340' side='right'caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2h1y' size='340' side='right'caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Helicobacter_pylori_(strain_ss1)~~ Helicobacter pylori ~~(strain ss1)~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_SS1 Helicobacter pylori SS1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>[~~https://en.wikipedia.org/wiki/~~[~~Acyl-carrier-protein~~]~~_S-malonyltransferase [Acyl-carrier-protein~~] ~~S-malonyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=~~2.~~3.1.39 2.3.1.39] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [https://pdbe.org/2h1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [https://www.ebi.ac.uk/pdbsum/2h1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h1y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [https://pdbe.org/2h1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [https://www.ebi.ac.uk/pdbsum/2h1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h1y ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q56S05_HELPX Q56S05_HELPX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Helicobacter pylori SS1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Jiang, H]]	+	[[Category: Jiang H]]
-	[[Category: Liu, W]]	+	[[Category: Liu W]]
-	[[Category: Shen, X]]	+	[[Category: Shen X]]
-	[[Category: Zhang, L]]	+	[[Category: Zhang L]]
-	~~[[Category: Fabd]]~~	+
-	~~[[Category: Mcat]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 10:00, 5 May 2021

OCA — Wed, 05 May 2021 10:00:01 GMT

←Older revision		Revision as of 10:00, 5 May 2021
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	<StructureSection load='2h1y' size='340' side='right'caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2h1y' size='340' side='right'caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [~~http~~://pdbe.org/2h1y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2h1y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2h1y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [https://pdbe.org/2h1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [https://www.ebi.ac.uk/pdbsum/2h1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h1y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 09:39, 24 July 2019

OCA — Wed, 24 Jul 2019 09:39:43 GMT

←Older revision		Revision as of 09:39, 24 July 2019
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	==Crystal structure of malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori==		==Crystal structure of malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori==
-	<StructureSection load='2h1y' size='340' side='right' caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='2h1y' size='340' side='right'caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/2h1y_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/2h1y_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Jiang, H]]		[[Category: Jiang, H]]
	[[Category: Liu, W]]		[[Category: Liu, W]]

OCA at 08:04, 18 October 2017

OCA — Wed, 18 Oct 2017 08:04:54 GMT

←Older revision		Revision as of 08:04, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori==		==Crystal structure of malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori==
	<StructureSection load='2h1y' size='340' side='right' caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2h1y' size='340' side='right' caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [http://pdbe.org/2h1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [http://www.ebi.ac.uk/pdbsum/2h1y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [http://pdbe.org/2h1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [http://www.ebi.ac.uk/pdbsum/2h1y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2h1y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 03:42, 9 February 2016

OCA — Tue, 09 Feb 2016 03:42:26 GMT

←Older revision		Revision as of 03:42, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h1y ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:16, 10 September 2015

OCA — Thu, 10 Sep 2015 18:16:32 GMT

←Older revision		Revision as of 18:16, 10 September 2015
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	<StructureSection load='2h1y' size='340' side='right' caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='2h1y' size='340' side='right' caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Helicobacter_pylori~~ Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_(strain_ss1) Helicobacter pylori (strain ss1)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [http://www.ebi.ac.uk/pdbsum/2h1y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [http://pdbe.org/2h1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [http://www.ebi.ac.uk/pdbsum/2h1y PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2h1y" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Helicobacter pylori]]
	[[Category: Jiang, H]]		[[Category: Jiang, H]]
	[[Category: Liu, W]]		[[Category: Liu, W]]

OCA at 08:46, 16 January 2015

OCA — Fri, 16 Jan 2015 08:46:08 GMT

←Older revision		Revision as of 08:46, 16 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [http://www.ebi.ac.uk/pdbsum/2h1y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [http://www.ebi.ac.uk/pdbsum/2h1y PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
-	[[Category: Jiang, H.]]	+	[[Category: Jiang, H]]
-	[[Category: Liu, W.]]	+	[[Category: Liu, W]]
-	[[Category: Shen, X.]]	+	[[Category: Shen, X]]
-	[[Category: Zhang, L.]]	+	[[Category: Zhang, L]]
	[[Category: Fabd]]		[[Category: Fabd]]
	[[Category: Mcat]]		[[Category: Mcat]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 10:19, 30 September 2014

OCA — Tue, 30 Sep 2014 10:19:18 GMT

←Older revision		Revision as of 10:19, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2h1y.~~png\|left~~\|200px]]	+	==Crystal structure of malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori==
		+	<StructureSection load='2h1y' size='340' side='right' caption='[[2h1y]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H1Y FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/[Acyl-carrier-protein]_S-malonyltransferase [Acyl-carrier-protein] S-malonyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.39 2.3.1.39] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h1y RCSB], [http://www.ebi.ac.uk/pdbsum/2h1y PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/2h1y_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Malonyl-CoA: acyl carrier protein transacylase (MCAT) is a critical enzyme responsible for the transfer of the malonyl moiety to holo-acyl carrier protein (ACP) forming the malonyl-ACP intermediates in the initiation step of type II fatty acid synthesis (FAS II) in bacteria. MCAT has been considered as an attractive drug target in the discovery of antibacterial agents. In this study, the crystal structure of MCAT from Helicobacter pylori (Hp) at 2.5 angstroms resolution is reported, and the interaction of HpMCAT with HpACP is extensively investigated by using computational docking, GST-pull-down, and surface plasmon resonance (SPR) technology-based assays. The crystal structure results reveal that HpMCAT has a compact folding composed of a large subdomain with a similar core as in alpha/beta hydrolases, and a similar ferredoxin-like small subdomain as in acylphosphatases. The docking result suggests two positively charged areas near the entrance of the active site of HpMCAT as the ACP-binding region. Binding assay research shows that HpMCAT demonstrates a moderately binding ability against HpACP. The solved 3D structure of HpMCAT is expected to supply useful information for the structure-based discovery of novel inhibitors against MCAT, and the quantitative study of HpMCAT interaction with HpACP is hoped to give helpful hints in the understanding of the detailed catalytic mechanisms for HpMCAT.

-	~~{{STRUCTURE_2h1y\| PDB=2h1y \| SCENE= }}~~	+	Malonyl-CoA: acyl carrier protein transacylase from Helicobacter pylori: Crystal structure and its interaction with acyl carrier protein.,Zhang L, Liu W, Xiao J, Hu T, Chen J, Chen K, Jiang H, Shen X Protein Sci. 2007 Jun;16(6):1184-92. PMID:17525466<ref>PMID:17525466</ref>

-	~~===Crystal structure~~ of ~~malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17525466}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2h1y]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Helicobacter_pylori Helicobacter pylori]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017525466<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
	[[Category: Jiang, H.]]		[[Category: Jiang, H.]]

OCA: Protected "2h1y" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 12:09:28 GMT

Protected "2h1y" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:09, 7 January 2013

OCA at 12:09, 7 January 2013

OCA — Mon, 07 Jan 2013 12:09:25 GMT

←Older revision		Revision as of 12:09, 7 January 2013
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-	{{Seed}}
	[[Image:2h1y.png\|left\|200px]]		[[Image:2h1y.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2h1y", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2h1y\| PDB=2h1y \| SCENE= }}		{{STRUCTURE_2h1y\| PDB=2h1y \| SCENE= }}

	===Crystal structure of malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori===		===Crystal structure of malonyl-CoA:Acyl carrier protein transacylase (MCAT) from Helicobacter pylori===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17525466}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17525466 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17525466}}		{{ABSTRACT_PUBMED_17525466}}

	==About this Structure==		==About this Structure==
-	~~2H1Y~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA].	+	[[2h1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H1Y OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17525466~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017525466</ref><references group="xtra"/>
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
	[[Category: Jiang, H.]]		[[Category: Jiang, H.]]
Line 31:		Line 19:
	[[Category: Fabd]]		[[Category: Fabd]]
	[[Category: Mcat]]		[[Category: Mcat]]
-		+	[[Category: Transferase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 06:11:23 2009''~~	+