2h8f - Revision history

OCA at 11:06, 5 January 2022

OCA — Wed, 05 Jan 2022 11:06:47 GMT

←Older revision		Revision as of 11:06, 5 January 2022
Line 3:		Line 3:
	<StructureSection load='2h8f' size='340' side='right'caption='[[2h8f]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2h8f' size='340' side='right'caption='[[2h8f]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2h8f]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2H8F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2h8f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H8F FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2aa1\|2aa1]], [[2h8d\|2h8d]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [~~http~~://pdbe.org/2h8f PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2h8f PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2h8f ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [https://pdbe.org/2h8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [https://www.ebi.ac.uk/pdbsum/2h8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h8f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HBA_TREBE HBA_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues. [[~~http~~://www.uniprot.org/uniprot/HBB_TREBE HBB_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues.	+	[[https://www.uniprot.org/uniprot/HBA_TREBE HBA_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues. [[https://www.uniprot.org/uniprot/HBB_TREBE HBB_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:07, 1 April 2020

OCA — Wed, 01 Apr 2020 10:07:00 GMT

←Older revision		Revision as of 10:07, 1 April 2020
Line 1:		Line 1:

	==Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2==		==Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2==
-	<StructureSection load='2h8f' size='340' side='right' caption='[[2h8f]], [[Resolution\|resolution]] 1.30Å' scene=''>	+	<StructureSection load='2h8f' size='340' side='right'caption='[[2h8f]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2h8f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H8F FirstGlance]. <br>		<table><tr><td colspan='2'>[[2h8f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H8F FirstGlance]. <br>
Line 37:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
	[[Category: Bonomi, G]]		[[Category: Bonomi, G]]

OCA at 06:34, 27 June 2018

OCA — Wed, 27 Jun 2018 06:34:28 GMT

←Older revision		Revision as of 06:34, 27 June 2018
Line 1:		Line 1:
		+
	==Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2==		==Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2==
	<StructureSection load='2h8f' size='340' side='right' caption='[[2h8f]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='2h8f' size='340' side='right' caption='[[2h8f]], [[Resolution\|resolution]] 1.30Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [http://pdbe.org/2h8f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [http://www.ebi.ac.uk/pdbsum/2h8f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [http://pdbe.org/2h8f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [http://www.ebi.ac.uk/pdbsum/2h8f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2h8f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h8f_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h8f_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h8f ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:49, 11 September 2015

OCA — Fri, 11 Sep 2015 07:49:10 GMT

←Older revision		Revision as of 07:49, 11 September 2015
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [http://www.ebi.ac.uk/pdbsum/2h8f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [http://pdbe.org/2h8f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [http://www.ebi.ac.uk/pdbsum/2h8f PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~HBA_PAGBE HBA_PAGBE~~]] Involved in oxygen transport from gills to the various peripheral tissues. [[http://www.uniprot.org/uniprot/~~HBB_PAGBE HBB_PAGBE~~]] Involved in oxygen transport from gills to the various peripheral tissues.	+	[[http://www.uniprot.org/uniprot/HBA_TREBE HBA_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues. [[http://www.uniprot.org/uniprot/HBB_TREBE HBB_TREBE]] Involved in oxygen transport from gills to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2h8f" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 13:27, 25 December 2014

OCA — Thu, 25 Dec 2014 13:27:26 GMT

←Older revision		Revision as of 13:27, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2h8f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H8F FirstGlance]. <br>		<table><tr><td colspan='2'>[[2h8f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H8F FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [http://www.ebi.ac.uk/pdbsum/2h8f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [http://www.ebi.ac.uk/pdbsum/2h8f PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HBA_PAGBE HBA_PAGBE]] Involved in oxygen transport from gills to the various peripheral tissues. [[http://www.uniprot.org/uniprot/HBB_PAGBE HBB_PAGBE]] Involved in oxygen transport from gills to the various peripheral tissues.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
-	[[Category: Bonomi, G.]]	+	[[Category: Bonomi, G]]
-	[[Category: Mazzarella, L.]]	+	[[Category: Mazzarella, L]]
-	[[Category: Merlino, A.]]	+	[[Category: Merlino, A]]
-	[[Category: Prisco, G di.]]	+	[[Category: Prisco, G di]]
-	[[Category: Scala, S.]]	+	[[Category: Scala, S]]
-	[[Category: Verde, C.]]	+	[[Category: Verde, C]]
-	[[Category: Vergara, A.]]	+	[[Category: Vergara, A]]
-	[[Category: Vitagliano, L.]]	+	[[Category: Vitagliano, L]]
	[[Category: Allostery]]		[[Category: Allostery]]
	[[Category: Cooperativity]]		[[Category: Cooperativity]]

OCA at 04:39, 29 September 2014

OCA — Mon, 29 Sep 2014 04:39:59 GMT

←Older revision		Revision as of 04:39, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2h8f.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2==
		+	<StructureSection load='2h8f' size='340' side='right' caption='[[2h8f]], [[Resolution\|resolution]] 1.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2h8f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H8F FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2aa1\|2aa1]], [[2h8d\|2h8d]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h8f RCSB], [http://www.ebi.ac.uk/pdbsum/2h8f PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h8f_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Root effect is a widespread property in fish hemoglobins (Hbs) that produces a drastic reduction of cooperativity and oxygen-binding ability at acidic pH. Here, we report the high-resolution structure of the deoxy form of Hb isolated from the Antarctic fish Trematomus bernacchii (HbTb) crystallized at pH 6.2 and 8.4. The structure at acidic pH has been previously determined at a moderate resolution (Ito et al., J Mol Biol 1995;250:648-658). Our results provide a clear picture of the events occurring upon the pH increase from 6.2 to 8.4, observed within a practically unchanged crystal environment. In particular, at pH 8.4, the interaspartic hydrogen bond at the alpha(1)beta(2) interface is partially broken, suggesting a pK(a) close to 8.4 for Asp95alpha. In addition, a detailed survey of the histidine modifications, caused by the change in pH, also indicates that at least three hot regions of the molecule are modified (Ebeta helix, Cbeta-tail, CDalpha corner) and can be considered to be involved at various levels in the release of the Root protons. Most importantly, at the CDalpha corner, the break of the salt bridge Asp48alpha-His55alpha allows us to describe a detailed mechanism that transmits the modification from the CDalpha corner far to the alpha heme. More generally, the results shed light on the role played by the histidine residues in modulating the strength of the Root effect and also support the emerging idea that the structural determinants, at least for a part of the Root effect, are specific of each Hb endowed with this property.

-	~~{{STRUCTURE_2h8f\| PDB=2h8f \| SCENE= }}~~	+	High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: the role of histidine residues in modulating the strength of the root effect.,Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, di Prisco G Proteins. 2006 Nov 1;65(2):490-8. PMID:16909420<ref>PMID:16909420</ref>

-	~~===Crystal structure~~ of ~~deoxy hemoglobin from Trematomus bernacchii at pH 6~~.~~2===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16909420}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2h8f]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA].~~	+

	==See Also==		==See Also==
-	*[[Hemoglobin\|Hemoglobin]]	+	*[[Hemoglobin 3D structures\|Hemoglobin 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016909420<~~/~~ref~~><~~ref group="xtra">PMID:016299734</ref><ref group="xtra">PMID:010222199</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
	[[Category: Bonomi, G.]]		[[Category: Bonomi, G.]]

OCA at 17:13, 20 October 2012

OCA — Sat, 20 Oct 2012 17:13:46 GMT

←Older revision		Revision as of 17:13, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[2h8f]] is a 4 chain structure ~~of [[Hemoglobin]]~~ with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA].	+	[[2h8f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA].

	==See Also==		==See Also==

OCA at 00:15, 27 July 2012

OCA — Fri, 27 Jul 2012 00:15:10 GMT

←Older revision		Revision as of 00:15, 27 July 2012
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	[[Image:2h8f.png\|left\|200px]]		[[Image:2h8f.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2h8f", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2h8f\| PDB=2h8f \| SCENE= }}		{{STRUCTURE_2h8f\| PDB=2h8f \| SCENE= }}

	===Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2===		===Crystal structure of deoxy hemoglobin from Trematomus bernacchii at pH 6.2===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16909420}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16909420 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_16909420}}		{{ABSTRACT_PUBMED_16909420}}

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	==See Also==		==See Also==
-	*[[Hemoglobin]]	+	*[[Hemoglobin\|Hemoglobin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16909420~~</ref><ref group="xtra">PMID:~~16299734~~</ref><ref group="xtra">PMID:~~10222199~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016909420</ref><ref group="xtra">PMID:016299734</ref><ref group="xtra">PMID:010222199</ref><references group="xtra"/>
	[[Category: Trematomus bernacchii]]		[[Category: Trematomus bernacchii]]
	[[Category: Bonomi, G.]]		[[Category: Bonomi, G.]]

OCA: Protected "2h8f" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 18:41:53 GMT

Protected "2h8f" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:41, 14 March 2011

OCA at 18:41, 14 March 2011

OCA — Mon, 14 Mar 2011 18:41:52 GMT

←Older revision		Revision as of 18:41, 14 March 2011
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-	{{Seed}}
	[[Image:2h8f.png\|left\|200px]]		[[Image:2h8f.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2H8F~~ is a 4 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA].	+	[[2h8f]] is a 4 chain structure of [[Hemoglobin]] with sequence from [http://en.wikipedia.org/wiki/Trematomus_bernacchii Trematomus bernacchii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8F OCA].
		+
		+	==See Also==
		+	*[[Hemoglobin]]

	==Reference==		==Reference==
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	[[Category: Ph]]		[[Category: Ph]]
	[[Category: Root effect]]		[[Category: Root effect]]
-		+	[[Category: Transport protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 17:24:04 2009''~~	+