2hax - Revision history

OCA at 09:54, 30 August 2023

OCA — Wed, 30 Aug 2023 09:54:36 GMT

←Older revision		Revision as of 09:54, 30 August 2023
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	<StructureSection load='2hax' size='340' side='right'caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>		<StructureSection load='2hax' size='340' side='right'caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~'bacillus_caldolyticus' 'bacillus~~ caldolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HAX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HAX FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)~~-~~2-METHYL-2~~,~~4-PENTANEDIOL'>MPD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.29Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">cspB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [https://pdbe.org/2hax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [https://www.ebi.ac.uk/pdbsum/2hax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hax ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [https://pdbe.org/2hax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [https://www.ebi.ac.uk/pdbsum/2hax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hax ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.	+	[https://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL] Affects cell viability at low temperatures.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus caldolyticus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Heinemann, U]]	+	[[Category: Heinemann U]]
-	[[Category: Max~~, K E.A]]~~	+	[[Category: Max KEA]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Gene regulation-dna complex]]~~	+
-	~~[[Category: Gene-expression regulator]]~~	+
-	~~[[Category: Protein-dna complex]]~~	+
-	~~[[Category: Single-stranded dna~~]]	+

OCA at 07:35, 17 March 2021

OCA — Wed, 17 Mar 2021 07:35:30 GMT

←Older revision		Revision as of 07:35, 17 March 2021
Line 1:		Line 1:

	==Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine==		==Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine==
-	<StructureSection load='2hax' size='340' side='right' caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>	+	<StructureSection load='2hax' size='340' side='right'caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/'bacillus_caldolyticus' 'bacillus caldolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2HAX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/'bacillus_caldolyticus' 'bacillus caldolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HAX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [~~http~~://pdbe.org/2hax PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2hax PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2hax ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [https://pdbe.org/2hax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [https://www.ebi.ac.uk/pdbsum/2hax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hax ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.	+	[[https://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ha/2hax_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ha/2hax_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
		+	[[Category: Large Structures]]
	[[Category: Heinemann, U]]		[[Category: Heinemann, U]]
	[[Category: Max, K E.A]]		[[Category: Max, K E.A]]

OCA at 08:09, 18 October 2017

OCA — Wed, 18 Oct 2017 08:09:03 GMT

←Older revision		Revision as of 08:09, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine==		==Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine==
	<StructureSection load='2hax' size='340' side='right' caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>		<StructureSection load='2hax' size='340' side='right' caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [http://pdbe.org/2hax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [http://www.ebi.ac.uk/pdbsum/2hax PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [http://pdbe.org/2hax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [http://www.ebi.ac.uk/pdbsum/2hax PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hax ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 18:19, 8 February 2016

OCA — Mon, 08 Feb 2016 18:19:46 GMT

←Older revision		Revision as of 18:19, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hax ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:10, 10 September 2015

OCA — Thu, 10 Sep 2015 14:10:49 GMT

←Older revision		Revision as of 14:10, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2hax' size='340' side='right' caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>		<StructureSection load='2hax' size='340' side='right' caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_caldolyticus Bacillus~~ caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HAX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/'bacillus_caldolyticus' 'bacillus caldolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HAX FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [http://www.ebi.ac.uk/pdbsum/2hax PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [http://pdbe.org/2hax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [http://www.ebi.ac.uk/pdbsum/2hax PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2hax" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 01:15, 25 December 2014

OCA — Thu, 25 Dec 2014 01:15:33 GMT

←Older revision		Revision as of 01:15, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HAX FirstGlance]. <br>		<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HAX FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [http://www.ebi.ac.uk/pdbsum/2hax PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [http://www.ebi.ac.uk/pdbsum/2hax PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
-	[[Category: Heinemann, U.]]	+	[[Category: Heinemann, U]]
-	[[Category: Max, K E.A.]]	+	[[Category: Max, K E.A]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Gene regulation-dna complex]]		[[Category: Gene regulation-dna complex]]

OCA at 08:40, 30 September 2014

OCA — Tue, 30 Sep 2014 08:40:57 GMT

←Older revision		Revision as of 08:40, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2hax.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine==
		+	<StructureSection load='2hax' size='340' side='right' caption='[[2hax]], [[Resolution\|resolution]] 1.29Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2hax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HAX FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1mjc\|1mjc]], [[2es2\|2es2]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">cspB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hax OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hax RCSB], [http://www.ebi.ac.uk/pdbsum/2hax PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ha/2hax_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bacterial cold shock proteins (CSPs) regulate cellular adaptation to cold stress. Functions ascribed to CSP include roles as RNA chaperones and in transcription antitermination. We present the crystal structure of the Bacillus caldolyticus CSP (Bc-Csp) in complex with hexathymidine (dT(6)) at a resolution of 1.29 A. Bound to dT(6), crystalline Bc-Csp forms a domain-swapped dimer in which beta strands 1-3 associate with strands 4 and 5 from the other subunit to form a closed beta barrel and vice versa. The globular units of dimeric Bc-Csp closely resemble the well-known structure of monomeric CSP. Structural reorganization from the monomer to the domain-swapped dimer involves a strictly localized change in the peptide bond linking Glu36 and Gly37 of Bc-Csp. Similar structural reorganizations have not been found in any other CSP or oligonucleotide/oligosaccharide-binding fold structures. Each dT(6) ligand is bound to one globular unit of Bc-Csp via an amphipathic protein surface. Individual binding subsites interact with the DNA bases through stacking and hydrogen bonding. The sugar-phosphate backbone remains solvent exposed. Based on crystallographic and biochemical studies of deoxyoligonucleotide binding to CSP, we suggest a common mode of binding of single-stranded heptanucleotide motifs to proteins containing cold shock domains, including the eukaryotic Y-box factors.

-	~~{{STRUCTURE_2hax\| PDB=2hax \| SCENE= }}~~	+	Common mode of DNA binding to cold shock domains. Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus.,Max KE, Zeeb M, Bienert R, Balbach J, Heinemann U FEBS J. 2007 Mar;274(5):1265-79. Epub 2007 Jan 31. PMID:17266726<ref>PMID:17266726</ref>

-	~~===Crystal structure~~ of ~~Bacillus caldolyticus cold shock protein in complex with hexathymidine===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17266726}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2hax]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017266726<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
	[[Category: Heinemann, U.]]		[[Category: Heinemann, U.]]

OCA: Protected "2hax" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 13:39:42 GMT

Protected "2hax" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:39, 7 January 2013

OCA at 13:39, 7 January 2013

OCA — Mon, 07 Jan 2013 13:39:39 GMT

←Older revision		Revision as of 13:39, 7 January 2013
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-	{{Seed}}
	[[Image:2hax.png\|left\|200px]]		[[Image:2hax.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2hax\| PDB=2hax \| SCENE= }}		{{STRUCTURE_2hax\| PDB=2hax \| SCENE= }}

	===Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine===		===Crystal structure of Bacillus caldolyticus cold shock protein in complex with hexathymidine===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17266726}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17266726 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_17266726}}		{{ABSTRACT_PUBMED_17266726}}

	==About this Structure==		==About this Structure==
-	~~2HAX~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA].	+	[[2hax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17266726~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017266726</ref><references group="xtra"/>
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
	[[Category: Heinemann, U.]]		[[Category: Heinemann, U.]]
	[[Category: Max, K E.A.]]		[[Category: Max, K E.A.]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
		+	[[Category: Gene regulation-dna complex]]
	[[Category: Gene-expression regulator]]		[[Category: Gene-expression regulator]]
	[[Category: Protein-dna complex]]		[[Category: Protein-dna complex]]
	[[Category: Single-stranded dna]]		[[Category: Single-stranded dna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 01:14:29 2009''

OCA at 23:14, 16 February 2009

OCA — Mon, 16 Feb 2009 23:14:35 GMT

←Older revision		Revision as of 23:14, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2HAX is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA].	+	2HAX is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAX OCA].

	==Reference==		==Reference==
-	Common mode of DNA binding to cold shock domains. Crystal structure of hexathymidine bound to the domain-swapped form of a major cold shock protein from Bacillus caldolyticus., Max KE, Zeeb M, Bienert R, Balbach J, Heinemann U, FEBS J. 2007 Mar;274(5):1265-79. Epub 2007 Jan 31. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17266726 17266726]~~	+	<ref group="xtra">PMID:17266726</ref><references group="xtra"/>
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
-	[[Category: Single protein]]
	[[Category: Heinemann, U.]]		[[Category: Heinemann, U.]]
	[[Category: Max, K E.A.]]		[[Category: Max, K E.A.]]
Line 33:		Line 32:
	[[Category: Single-stranded dna]]		[[Category: Single-stranded dna]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 6 00~~:58:~~28 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 01:14:29 2009''