2hgo - Revision history

OCA at 13:06, 26 July 2023

OCA — Wed, 26 Jul 2023 13:06:19 GMT

←Older revision		Revision as of 13:06, 26 July 2023
Line 1:		Line 1:

	==NMR structure of Cassiicolin==		==NMR structure of Cassiicolin==
-	<StructureSection load='2hgo' size='340' side='right'caption='[[2hgo~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2hgo' size='340' side='right'caption='[[2hgo]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Corcc Corcc~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HGO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynespora_cassiicola Corynespora cassiicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HGO FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [https://pdbe.org/2hgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [https://www.ebi.ac.uk/pdbsum/2hgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hgo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [https://pdbe.org/2hgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [https://www.ebi.ac.uk/pdbsum/2hgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hgo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CASSI_CORCC CASSI_CORCC]] Toxin, essential for pathogenicity. Causes symptoms of Corynespora leaf fall disease (CLF) in rubber trees, including chlorosis, development of brown spots and necrosis. Alters leaf cell ultrastructure, causing plasmolysis in most cell types. In extreme cases the plasmolysis leads to disruption of the plasma membrane. Also affects chloroplast structure, causing lamellae distortion and reduced thylakoids stacking together. Causes accumulation of starch grains. Does not affect the nucleus or mitochondria. Toxic to N.tabacum, L.esculentum, S.ionantha, F.lyrata, P.violacea, S.melongena, and G.max. Not toxic to P.alba, G.hirsutum, P.acerifolia, R.pseudoacacia, T.zebrina, M.alba, and Q.ilex.<ref>PMID:17234212</ref> <ref>PMID:17234212</ref> <ref>PMID:17113837</ref>	+	[https://www.uniprot.org/uniprot/CASSI_CORCC CASSI_CORCC] Toxin, essential for pathogenicity. Causes symptoms of Corynespora leaf fall disease (CLF) in rubber trees, including chlorosis, development of brown spots and necrosis. Alters leaf cell ultrastructure, causing plasmolysis in most cell types. In extreme cases the plasmolysis leads to disruption of the plasma membrane. Also affects chloroplast structure, causing lamellae distortion and reduced thylakoids stacking together. Causes accumulation of starch grains. Does not affect the nucleus or mitochondria. Toxic to N.tabacum, L.esculentum, S.ionantha, F.lyrata, P.violacea, S.melongena, and G.max. Not toxic to P.alba, G.hirsutum, P.acerifolia, R.pseudoacacia, T.zebrina, M.alba, and Q.ilex.<ref>PMID:17234212</ref> <ref>PMID:17234212</ref> <ref>PMID:17113837</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Corcc~~]]	+	[[Category: Corynespora cassiicola]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Barthe, P]]	+	[[Category: Barthe P]]
-	~~[[Category: Lamotte, F de~~]]	+	[[Category: Pujade-Renault V]]
-	[[Category: Pujade-Renault, V]]	+	[[Category: Roumestand C]]
-	[[Category: Roumestand, C]]	+	[[Category: De Lamotte F]]
-	[[Category: ~~Disulfide bridge]]~~	+
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 20:41, 20 October 2021

OCA — Wed, 20 Oct 2021 20:41:41 GMT

←Older revision		Revision as of 20:41, 20 October 2021
Line 3:		Line 3:
	<StructureSection load='2hgo' size='340' side='right'caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2hgo' size='340' side='right'caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Corcc Corcc]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2HGO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Corcc Corcc]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HGO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [~~http~~://pdbe.org/2hgo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2hgo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2hgo ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [https://pdbe.org/2hgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [https://www.ebi.ac.uk/pdbsum/2hgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hgo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CASSI_CORCC CASSI_CORCC]] Toxin, essential for pathogenicity. Causes symptoms of Corynespora leaf fall disease (CLF) in rubber trees, including chlorosis, development of brown spots and necrosis. Alters leaf cell ultrastructure, causing plasmolysis in most cell types. In extreme cases the plasmolysis leads to disruption of the plasma membrane. Also affects chloroplast structure, causing lamellae distortion and reduced thylakoids stacking together. Causes accumulation of starch grains. Does not affect the nucleus or mitochondria. Toxic to N.tabacum, L.esculentum, S.ionantha, F.lyrata, P.violacea, S.melongena, and G.max. Not toxic to P.alba, G.hirsutum, P.acerifolia, R.pseudoacacia, T.zebrina, M.alba, and Q.ilex.<ref>PMID:17234212</ref> <ref>PMID:17234212</ref> <ref>PMID:17113837</ref>	+	[[https://www.uniprot.org/uniprot/CASSI_CORCC CASSI_CORCC]] Toxin, essential for pathogenicity. Causes symptoms of Corynespora leaf fall disease (CLF) in rubber trees, including chlorosis, development of brown spots and necrosis. Alters leaf cell ultrastructure, causing plasmolysis in most cell types. In extreme cases the plasmolysis leads to disruption of the plasma membrane. Also affects chloroplast structure, causing lamellae distortion and reduced thylakoids stacking together. Causes accumulation of starch grains. Does not affect the nucleus or mitochondria. Toxic to N.tabacum, L.esculentum, S.ionantha, F.lyrata, P.violacea, S.melongena, and G.max. Not toxic to P.alba, G.hirsutum, P.acerifolia, R.pseudoacacia, T.zebrina, M.alba, and Q.ilex.<ref>PMID:17234212</ref> <ref>PMID:17234212</ref> <ref>PMID:17113837</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:41, 25 December 2019

OCA — Wed, 25 Dec 2019 09:41:12 GMT

←Older revision		Revision as of 09:41, 25 December 2019
Line 1:		Line 1:

	==NMR structure of Cassiicolin==		==NMR structure of Cassiicolin==
-	<StructureSection load='2hgo' size='340' side='right' caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2hgo' size='340' side='right'caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corcc Corcc]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HGO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corcc Corcc]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HGO FirstGlance]. <br>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Corcc]]		[[Category: Corcc]]
		+	[[Category: Large Structures]]
	[[Category: Barthe, P]]		[[Category: Barthe, P]]
	[[Category: Lamotte, F de]]		[[Category: Lamotte, F de]]

OCA at 06:19, 27 June 2018

OCA — Wed, 27 Jun 2018 06:19:49 GMT

←Older revision		Revision as of 06:19, 27 June 2018
Line 1:		Line 1:
		+
	==NMR structure of Cassiicolin==		==NMR structure of Cassiicolin==
	<StructureSection load='2hgo' size='340' side='right' caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2hgo' size='340' side='right' caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://pdbe.org/2hgo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://pdbe.org/2hgo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hgo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 13:37, 11 September 2015

OCA — Fri, 11 Sep 2015 13:37:15 GMT

←Older revision		Revision as of 13:37, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2hgo' size='340' side='right' caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2hgo' size='340' side='right' caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Corynespora_cassiicola Corynespora cassiicola~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HGO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corcc Corcc]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HGO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://pdbe.org/2hgo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2hgo" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Corynespora cassiicola~~]]	+	[[Category: Corcc]]
	[[Category: Barthe, P]]		[[Category: Barthe, P]]
	[[Category: Lamotte, F de]]		[[Category: Lamotte, F de]]

OCA at 17:10, 25 December 2014

OCA — Thu, 25 Dec 2014 17:10:41 GMT

←Older revision		Revision as of 17:10, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CASSI_CORCC CASSI_CORCC]] Toxin, essential for pathogenicity. Causes symptoms of Corynespora leaf fall disease (CLF) in rubber trees, including chlorosis, development of brown spots and necrosis. Alters leaf cell ultrastructure, causing plasmolysis in most cell types. In extreme cases the plasmolysis leads to disruption of the plasma membrane. Also affects chloroplast structure, causing lamellae distortion and reduced thylakoids stacking together. Causes accumulation of starch grains. Does not affect the nucleus or mitochondria. Toxic to N.tabacum, L.esculentum, S.ionantha, F.lyrata, P.violacea, S.melongena, and G.max. Not toxic to P.alba, G.hirsutum, P.acerifolia, R.pseudoacacia, T.zebrina, M.alba, and Q.ilex.<ref>PMID:17234212</ref> <ref>PMID:17234212</ref> <ref>PMID:17113837</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 05:04, 22 December 2014

OCA — Mon, 22 Dec 2014 05:04:35 GMT

←Older revision		Revision as of 05:04, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynespora_cassiicola Corynespora cassiicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HGO FirstGlance]. <br>		<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynespora_cassiicola Corynespora cassiicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HGO FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Corynespora cassiicola]]		[[Category: Corynespora cassiicola]]
-	[[Category: Barthe, P.]]	+	[[Category: Barthe, P]]
-	[[Category: Lamotte, F de.]]	+	[[Category: Lamotte, F de]]
-	[[Category: Pujade-Renault, V.]]	+	[[Category: Pujade-Renault, V]]
-	[[Category: Roumestand, C.]]	+	[[Category: Roumestand, C]]
	[[Category: Disulfide bridge]]		[[Category: Disulfide bridge]]
	[[Category: Glycoprotein]]		[[Category: Glycoprotein]]
	[[Category: Toxin]]		[[Category: Toxin]]

OCA at 06:52, 9 June 2014

OCA — Mon, 09 Jun 2014 06:52:05 GMT

←Older revision		Revision as of 06:52, 9 June 2014
Line 1:		Line 1:
-	[[~~Image:~~2hgo.~~png~~\|~~left~~\|~~200px~~]]	+	==NMR structure of Cassiicolin==
		+	<StructureSection load='2hgo' size='340' side='right' caption='[[2hgo]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynespora_cassiicola Corynespora cassiicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HGO FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3HD:3-O-METHYL-O-ALPHA-D-MANNOPYRANOSYL'>3HD</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hgo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hgo RCSB], [http://www.ebi.ac.uk/pdbsum/2hgo PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cassiicolin is a host-selective toxin (HST) produced by the fungus Corynespora cassiicola (strain CCP). It is responsible for the Corynespora leaf fall (CLF) disease, which is among the main pathologies affecting rubber tree (Hevea brasiliensis). Working on purified cassiicolin and using electron microscopy, we have demonstrated that this 27-residue O-glycosylated protein is able to induce cellular damages identical to those induced by the fungus on rubber tree leaves and displays the same host selectivity. The solution structure and disulfide pairing of cassiicolin have been determined using NMR spectroscopy and simulated annealing calculations. Cassiicolin appears to have an original structure with a prolate ellipsoid shape. It adopts an over-all fold consisting of three strands arranged in a right-handed twisted, antiparallel beta-sheet knitted by three disulfide bonds. Its conformation resembles that found in small trypsine-like inhibitors isolated from the brain, the fat body and the hemolymph of locust grasshoppers. But cassiicolin has no sequence homology with these protease inhibitors, and lacks their characteristic substrate-binding loop. Probably, this motif represents one of the few highly stabilized "minimal" scaffolds, with a high sequence permissiveness, that nature has selected to evolve over different phyla and to support different functions. The knowledge of the 3D structure opens the way to the delineation of the mechanism of action of the toxin using site-directed mutagenesis.

-	~~{{STRUCTURE_2hgo\| PDB=2hgo \| SCENE= }}~~	+	Structural analysis of cassiicolin, a host-selective protein toxin from Corynespora cassiicola.,Barthe P, Pujade-Renaud V, Breton F, Gargani D, Thai R, Roumestand C, de Lamotte F J Mol Biol. 2007 Mar 16;367(1):89-101. Epub 2006 Dec 5. PMID:17234212<ref>PMID:17234212</ref>

-	~~===NMR structure~~ of ~~Cassiicolin===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17234212}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2hgo]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Corynespora_cassiicola Corynespora cassiicola]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017234212<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Corynespora cassiicola]]		[[Category: Corynespora cassiicola]]
	[[Category: Barthe, P.]]		[[Category: Barthe, P.]]

OCA: Protected "2hgo" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 15:03:46 GMT

Protected "2hgo" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:03, 14 August 2012

OCA at 15:03, 14 August 2012

OCA — Tue, 14 Aug 2012 15:03:45 GMT

←Older revision		Revision as of 15:03, 14 August 2012
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-	{{Seed}}
	[[Image:2hgo.png\|left\|200px]]		[[Image:2hgo.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2hgo", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_2hgo\| PDB=2hgo \| SCENE= }}		{{STRUCTURE_2hgo\| PDB=2hgo \| SCENE= }}

	===NMR structure of Cassiicolin===		===NMR structure of Cassiicolin===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17234212}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17234212 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_17234212}}		{{ABSTRACT_PUBMED_17234212}}

	==About this Structure==		==About this Structure==
-	~~2HGO is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Corynespora_cassiicola Corynespora cassiicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA].	+	[[2hgo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynespora_cassiicola Corynespora cassiicola]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HGO OCA].

	==Reference==		==Reference==
-	Structural analysis of cassiicolin, a host-selective protein toxin from Corynespora cassiicola., Barthe P, Pujade-Renaud V, Breton F, Gargani D, Thai R, Roumestand C, de Lamotte F, J Mol Biol. 2007 Mar 16;367(1):89-101. Epub 2006 Dec 5. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~17234212 17234212]~~	+	<ref group="xtra">PMID:017234212</ref><references group="xtra"/>
	[[Category: Corynespora cassiicola]]		[[Category: Corynespora cassiicola]]
-	[[Category: Single protein]]
	[[Category: Barthe, P.]]		[[Category: Barthe, P.]]
	[[Category: Lamotte, F de.]]		[[Category: Lamotte, F de.]]
Line 33:		Line 20:
	[[Category: Glycoprotein]]		[[Category: Glycoprotein]]
	[[Category: Toxin]]		[[Category: Toxin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:00:21 2008''