2hie - Revision history

OCA at 11:09, 5 January 2022

OCA — Wed, 05 Jan 2022 11:09:16 GMT

←Older revision		Revision as of 11:09, 5 January 2022
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	<StructureSection load='2hie' size='340' side='right'caption='[[2hie]]' scene=''>		<StructureSection load='2hie' size='340' side='right'caption='[[2hie]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2HIE FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HIE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2hie FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/2hie PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2hie ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hie FirstGlance], [https://www.ebi.ac.uk/pdbsum/2hie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hie ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:10, 1 April 2020

OCA — Wed, 01 Apr 2020 10:10:37 GMT

←Older revision		Revision as of 10:10, 1 April 2020
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	==A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2==		==A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2==
-	<StructureSection load='2hie' size='340' side='right' caption='[[2hie]]' scene=''>	+	<StructureSection load='2hie' size='340' side='right'caption='[[2hie]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIE FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIE FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Ealick, S]]		[[Category: Ealick, S]]
	[[Category: Hruza, A]]		[[Category: Hruza, A]]

OCA at 06:44, 27 June 2018

OCA — Wed, 27 Jun 2018 06:44:05 GMT

←Older revision		Revision as of 06:44, 27 June 2018
Line 5:		Line 5:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIE FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIE FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hie FirstGlance], [http://www.ebi.ac.uk/pdbsum/2hie PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hie FirstGlance], [http://www.ebi.ac.uk/pdbsum/2hie PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hie ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:48, 11 February 2016

OCA — Thu, 11 Feb 2016 10:48:40 GMT

←Older revision		Revision as of 10:48, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2==		==A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2==
	<StructureSection load='2hie' size='340' side='right' caption='[[2hie]]' scene=''>		<StructureSection load='2hie' size='340' side='right' caption='[[2hie]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Ealick, S]]		[[Category: Ealick, S]]
	[[Category: Hruza, A]]		[[Category: Hruza, A]]

OCA at 04:13, 11 September 2015

OCA — Fri, 11 Sep 2015 04:13:02 GMT

←Older revision		Revision as of 04:13, 11 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2hie" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:19, 16 January 2015

OCA — Fri, 16 Jan 2015 09:19:32 GMT

←Older revision		Revision as of 09:19, 16 January 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIE FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIE FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hie FirstGlance], [http://www.ebi.ac.uk/pdbsum/2hie PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hie FirstGlance], [http://www.ebi.ac.uk/pdbsum/2hie PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 00:58, 2 October 2014

OCA — Thu, 02 Oct 2014 00:58:19 GMT

←Older revision		Revision as of 00:58, 2 October 2014
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-	~~{{Theoretical_model}}~~	+	==A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2==
		+	<StructureSection load='2hie' size='340' side='right' caption='[[2hie]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HIE FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hie FirstGlance], [http://www.ebi.ac.uk/pdbsum/2hie PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	An atomic coordinate five alpha-helix three-dimensional model is presented for human interferon alpha-2 (HuIFN alpha 2). The HuIFN alpha 2 structure was constructed from murine interferon beta (MuIFN beta) by homology modeling using the STEREO and IMPACT programs. The HuIFN alpha 2 model is consistent with its known biochemical and biophysical properties including epitope mapping. Lysine residues predicted to be buried in the model were primarily unreactive with succinimidyl-7-amino-4-methylcoumarin-3-acetic acid (AMCA-NHS), a lysine modification agent, as shown by mass spectrometric analysis of tryptic digests. N-terminal sequence analysis of polypeptides generated by limited digestion of HuIFN alpha 2 with endoproteinase Lys-C demonstrated rapid cleavage at K31, which is consistent with the presence of this residue in a loop in the proposed HuIFN alpha 2 model. Based on this model structure potential receptor binding sites are identified.

-	~~[[Image~~:~~2hie~~.~~png\|left\|200px]]~~	+	A homology model of human interferon alpha-2.,Murgolo NJ, Windsor WT, Hruza A, Reichert P, Tsarbopoulos A, Baldwin S, Huang E, Pramanik B, Ealick S, Trotta PP Proteins. 1993 Sep;17(1):62-74. PMID:8234245<ref>PMID:8234245</ref>

-	~~{{STRUCTURE_2hie\| PDB=2hie \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	==~~=A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_8234245}}~~	+	__TOC__
-		+	</StructureSection>
-	~~==Reference~~==	+
-	<~~ref group="xtra">PMID:008234245<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Ealick, S]]		[[Category: Ealick, S]]
	[[Category: Hruza, A]]		[[Category: Hruza, A]]

OCA: Protected "2hie" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 09:54:19 GMT

Protected "2hie" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:54, 21 October 2012

OCA at 09:54, 21 October 2012

OCA — Sun, 21 Oct 2012 09:54:14 GMT

←Older revision		Revision as of 09:54, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:2hie.png\|left\|200px]]		[[Image:2hie.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2hie", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2hie\| PDB=2hie \| SCENE= }}		{{STRUCTURE_2hie\| PDB=2hie \| SCENE= }}

	===A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2===		===A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_8234245}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 8234245 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_8234245}}		{{ABSTRACT_PUBMED_8234245}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIE OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~8234245~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:008234245</ref><references group="xtra"/>
	[[Category: Ealick, S]]		[[Category: Ealick, S]]
	[[Category: Hruza, A]]		[[Category: Hruza, A]]
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	[[Category: Trotta, P P]]		[[Category: Trotta, P P]]
	[[Category: Windsor, W T]]		[[Category: Windsor, W T]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 09:11:38 2010''

OCA at 06:11, 8 April 2010

OCA — Thu, 08 Apr 2010 06:11:39 GMT

←Older revision		Revision as of 06:11, 8 April 2010
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-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:2hie.png\|left\|200px]]

-	The ~~entry 2HIE~~ is ~~a Theoretical Model titled 'A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2'~~.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2hie", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2hie\| PDB=2hie \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===A HOMOLOGY MODEL OF HUMAN INTERFERON ALPHA-2===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30~~ 09:57:~~27 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_8234245}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 8234245 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_8234245}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HIE OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:8234245</ref><references group="xtra"/>
		+	[[Category: Ealick, S]]
		+	[[Category: Hruza, A]]
		+	[[Category: Murgolo, N J]]
		+	[[Category: Reichert, P]]
		+	[[Category: Trotta, P P]]
		+	[[Category: Windsor, W T]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 09:11:38 2010''