2hxa - Revision history

OCA at 07:23, 24 March 2021

OCA — Wed, 24 Mar 2021 07:23:46 GMT

←Older revision		Revision as of 07:23, 24 March 2021
Line 1:		Line 1:

	==Crystal structure of Cu(I) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3.5==		==Crystal structure of Cu(I) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3.5==
-	<StructureSection load='2hxa' size='340' side='right' caption='[[2hxa]], [[Resolution\|resolution]] 2.21Å' scene=''>	+	<StructureSection load='2hxa' size='340' side='right'caption='[[2hxa]], [[Resolution\|resolution]] 2.21Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hxa]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2HXA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hxa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HXA FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [~~http~~://pdbe.org/2hxa PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2hxa PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2hxa ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [https://pdbe.org/2hxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [https://www.ebi.ac.uk/pdbsum/2hxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hxa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.	+	[[https://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 2hxa" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2hxa" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Azurin\|Azurin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]

OCA at 08:34, 4 July 2018

OCA — Wed, 04 Jul 2018 08:34:44 GMT

←Older revision		Revision as of 08:34, 4 July 2018
Line 1:		Line 1:
		+
	==Crystal structure of Cu(I) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3.5==		==Crystal structure of Cu(I) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3.5==
	<StructureSection load='2hxa' size='340' side='right' caption='[[2hxa]], [[Resolution\|resolution]] 2.21Å' scene=''>		<StructureSection load='2hxa' size='340' side='right' caption='[[2hxa]], [[Resolution\|resolution]] 2.21Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [http://pdbe.org/2hxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [http://www.ebi.ac.uk/pdbsum/2hxa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [http://pdbe.org/2hxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [http://www.ebi.ac.uk/pdbsum/2hxa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2hxa ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hxa_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hxa_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 07:00, 10 February 2016

OCA — Wed, 10 Feb 2016 07:00:48 GMT

←Older revision		Revision as of 07:00, 10 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hxa ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:29, 11 September 2015

OCA — Fri, 11 Sep 2015 06:29:51 GMT

←Older revision		Revision as of 06:29, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2hxa' size='340' side='right' caption='[[2hxa]], [[Resolution\|resolution]] 2.21Å' scene=''>		<StructureSection load='2hxa' size='340' side='right' caption='[[2hxa]], [[Resolution\|resolution]] 2.21Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2hxa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa Pseudomonas aeruginosa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HXA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2hxa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HXA FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 ~~Pseudomonas aeruginosa~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [http://www.ebi.ac.uk/pdbsum/2hxa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [http://pdbe.org/2hxa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [http://www.ebi.ac.uk/pdbsum/2hxa PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2hxa" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Pseudomonas aeruginosa]]
	[[Category: Banfield, M J]]		[[Category: Banfield, M J]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]

OCA at 12:35, 25 December 2014

OCA — Thu, 25 Dec 2014 12:35:59 GMT

←Older revision		Revision as of 12:35, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2hxa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HXA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2hxa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HXA FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [http://www.ebi.ac.uk/pdbsum/2hxa PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [http://www.ebi.ac.uk/pdbsum/2hxa PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AZUR_PSEAE AZUR_PSEAE]] Transfers electrons from cytochrome c551 to cytochrome oxidase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Banfield, M J.]]	+	[[Category: Banfield, M J]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]
	[[Category: Electron transport]]		[[Category: Electron transport]]
	[[Category: Greek-key beta-barrel]]		[[Category: Greek-key beta-barrel]]
	[[Category: Loop mutagenesis]]		[[Category: Loop mutagenesis]]

OCA at 10:12, 30 September 2014

OCA — Tue, 30 Sep 2014 10:12:29 GMT

←Older revision		Revision as of 10:12, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2hxa.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of Cu(I) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3.5==
		+	<StructureSection load='2hxa' size='340' side='right' caption='[[2hxa]], [[Resolution\|resolution]] 2.21Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2hxa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2HXA FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2fta\|2fta]], [[2ft6\|2ft6]], [[2ft7\|2ft7]], [[2ft8\|2ft8]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azu ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2hxa RCSB], [http://www.ebi.ac.uk/pdbsum/2hxa PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/2hxa_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ligand-containing loops of two copper-binding electron-transfer proteins (cupredoxins) have been swapped. In the azurin (AZ) variant in which the plastocyanin (PC) sequence is introduced (AZPC), the loop adopts a conformation identical to that in PC. The reduction potential of AZPC is raised as compared to AZ and matches that of PC. In the previously published AZAMI variant (AMI = amicyanin), the shorter introduced loop adopts the same conformation as in AMI, and the reduction potential is lowered to equal that of AMI (Yanagisawa, S.; Dennison, C. J. Am. Chem. Soc. 2004, 126, 15711-15719. Li, C.; et al. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 7258-7263). Thus, the loop structure plays an important role in tuning the reduction potential of a type 1 copper site with contributions from protein dipoles in this region probably the most important feature. The structure of the loop also seems to be a major factor in controlling dissociation and protonation of the C-terminal His ligand, which can act as a switch to regulate electron-transfer reactivity. The PCAZ variant (PC with the AZ loop) possesses an active site, which is different from those of both PC and AZ, and it is assumed that the introduced loop does not adopt a structure as in AZ. This contributes to the observed instability of PCAZ and highlights that loop-scaffold interactions are important for stabilizing the active site of a cupredoxin.

-	~~{{STRUCTURE_2hxa\| PDB=2hxa \| SCENE= }}~~	+	Engineering copper sites in proteins: loops confer native structures and properties to chimeric cupredoxins.,Li C, Banfield MJ, Dennison C J Am Chem Soc. 2007 Jan 24;129(3):709-18. PMID:17227035<ref>PMID:17227035</ref>

-	~~===Crystal structure~~ of ~~Cu(I) Azurin with~~ the ~~metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3~~.~~5===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_17227035}}~~	+	==See Also==
-		+	*[[Azurin\|Azurin]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~2hxa~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:017227035<~~/~~ref~~><~~ref group="xtra">PMID:016651527</ref><references group="xtra"~~/>	+
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Banfield, M J.]]		[[Category: Banfield, M J.]]

OCA at 13:16, 30 January 2013

OCA — Wed, 30 Jan 2013 13:16:04 GMT

←Older revision		Revision as of 13:16, 30 January 2013
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	[[Image:2hxa.png\|left\|200px]]		[[Image:2hxa.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2hxa", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_2hxa\| PDB=2hxa \| SCENE= }}		{{STRUCTURE_2hxa\| PDB=2hxa \| SCENE= }}

	===Crystal structure of Cu(I) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3.5===		===Crystal structure of Cu(I) Azurin with the metal-binding loop sequence "CTFPGHSALM" replaced with "CSPHQGAGM", at pH3.5===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17227035}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_17227035}}		{{ABSTRACT_PUBMED_17227035}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17227035~~</ref><ref group="xtra">PMID:~~16651527~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017227035</ref><ref group="xtra">PMID:016651527</ref><references group="xtra"/>
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
	[[Category: Banfield, M J.]]		[[Category: Banfield, M J.]]

OCA: Protected "2hxa" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 22:47:56 GMT

Protected "2hxa" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:47, 14 March 2011

OCA at 22:47, 14 March 2011

OCA — Mon, 14 Mar 2011 22:47:54 GMT

←Older revision		Revision as of 22:47, 14 March 2011
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-	{{Seed}}
	[[Image:2hxa.png\|left\|200px]]		[[Image:2hxa.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~2HXA~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA].	+	[[2hxa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA].

	==Reference==		==Reference==
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	[[Category: Banfield, M J.]]		[[Category: Banfield, M J.]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]
		+	[[Category: Electron transport]]
	[[Category: Greek-key beta-barrel]]		[[Category: Greek-key beta-barrel]]
	[[Category: Loop mutagenesis]]		[[Category: Loop mutagenesis]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:20:14 2009''

OCA at 14:20, 17 February 2009

OCA — Tue, 17 Feb 2009 14:20:15 GMT

←Older revision		Revision as of 14:20, 17 February 2009
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	==About this Structure==		==About this Structure==
-	2HXA is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA].	+	2HXA is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXA OCA].

	==Reference==		==Reference==
-	~~Engineering copper sites in proteins: loops confer native structures and properties to chimeric cupredoxins., Li C, Banfield MJ, Dennison C, J Am Chem Soc. 2007 Jan 24;129(3):709-18.~~ PMID:~~[http:~~/~~/www.ncbi.nlm.nih.gov/pubmed/17227035 17227035]~~	+	<ref group="xtra">PMID:17227035</ref><ref group="xtra">PMID:16651527</ref><references group="xtra"/>
-		+
-	Basic requirements for a metal-binding site in a protein: the influence of loop shortening on the cupredoxin azurin., Li C, Yanagisawa S, Martins BM, Messerschmidt A, Banfield MJ, Dennison C, Proc Natl Acad Sci U S A. 2006 May 9;103(19):7258-63. Epub 2006 May 1. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/16651527 16651527]~~	+
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Single protein]]
	[[Category: Banfield, M J.]]		[[Category: Banfield, M J.]]
	[[Category: Blue copper-binding protein]]		[[Category: Blue copper-binding protein]]
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	[[Category: Loop mutagenesis]]		[[Category: Loop mutagenesis]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Jul 28 22~~:54:~~36 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:20:14 2009''