2i1q - Revision history

OCA at 10:05, 30 August 2023

OCA — Wed, 30 Aug 2023 10:05:00 GMT

←Older revision		Revision as of 10:05, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='2i1q' size='340' side='right'caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2i1q' size='340' side='right'caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_33273 Atcc 33273~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1z4d\|1z4d]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 ATCC 33273])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [https://pdbe.org/2i1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [https://www.ebi.ac.uk/pdbsum/2i1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i1q ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [https://pdbe.org/2i1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [https://www.ebi.ac.uk/pdbsum/2i1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i1q ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/RADA_METVO RADA_METVO]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).	+	[https://www.uniprot.org/uniprot/RADA_METVO RADA_METVO] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 33273]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fodje~~, M N~~]]	+	[[Category: Methanococcus voltae]]
-	[[Category: Grochulski, P]]	+	[[Category: Fodje MN]]
-	[[Category: He, Y]]	+	[[Category: Grochulski P]]
-	[[Category: Luo, Y]]	+	[[Category: He Y]]
-	[[Category: Ma, X]]	+	[[Category: Luo Y]]
-	[[Category: Qian, X]]	+	[[Category: Ma X]]
-	~~[[Category: Atp complex]]~~	+	[[Category: Qian X]]
-	~~[[Category: Atpase]]~~	+
-	~~[[Category: Calcium stimulation]]~~	+
-	~~[[Category: Dmc1]]~~	+
-	~~[[Category: Rad51]]~~	+
-	~~[[Category: Rada]]~~	+
-	~~[[Category: Reca]]~~	+
-	~~[[Category: Recombinase]]~~	+
-	~~[[Category: Recombination~~]]	+

OCA at 07:26, 24 March 2021

OCA — Wed, 24 Mar 2021 07:26:23 GMT

←Older revision		Revision as of 07:26, 24 March 2021
Line 1:		Line 1:

	==RadA Recombinase in complex with Calcium==		==RadA Recombinase in complex with Calcium==
-	<StructureSection load='2i1q' size='340' side='right' caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='2i1q' size='340' side='right'caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_33273 Atcc 33273]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_33273 Atcc 33273]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1z4d\|1z4d]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 ATCC 33273])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 ATCC 33273])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [~~http~~://pdbe.org/2i1q PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2i1q PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2i1q ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [https://pdbe.org/2i1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [https://www.ebi.ac.uk/pdbsum/2i1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i1q ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/RADA_METVO RADA_METVO]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).	+	[[https://www.uniprot.org/uniprot/RADA_METVO RADA_METVO]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/2i1q_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/2i1q_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 2i1q" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2i1q" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Resolvase 3D structures\|Resolvase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 33273]]		[[Category: Atcc 33273]]
		+	[[Category: Large Structures]]
	[[Category: Fodje, M N]]		[[Category: Fodje, M N]]
	[[Category: Grochulski, P]]		[[Category: Grochulski, P]]

OCA at 08:21, 18 October 2017

OCA — Wed, 18 Oct 2017 08:21:43 GMT

←Older revision		Revision as of 08:21, 18 October 2017
Line 1:		Line 1:
		+
	==RadA Recombinase in complex with Calcium==		==RadA Recombinase in complex with Calcium==
	<StructureSection load='2i1q' size='340' side='right' caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2i1q' size='340' side='right' caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 ATCC 33273])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 ATCC 33273])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [http://pdbe.org/2i1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [http://www.ebi.ac.uk/pdbsum/2i1q PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [http://pdbe.org/2i1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [http://www.ebi.ac.uk/pdbsum/2i1q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2i1q ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 29:		Line 30:
	</div>		</div>
	<div class="pdbe-citations 2i1q" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2i1q" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Resolvase\|Resolvase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:29, 8 February 2016

OCA — Mon, 08 Feb 2016 20:29:10 GMT

←Older revision		Revision as of 20:29, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i1q ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:08, 10 September 2015

OCA — Thu, 10 Sep 2015 15:08:01 GMT

←Older revision		Revision as of 15:08, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2i1q' size='340' side='right' caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='2i1q' size='340' side='right' caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Methanococcus_voltae Methanococcus voltae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33273 Atcc 33273]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 ~~Methanococcus voltae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 ATCC 33273])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [http://www.ebi.ac.uk/pdbsum/2i1q PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [http://pdbe.org/2i1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [http://www.ebi.ac.uk/pdbsum/2i1q PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2i1q" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Methanococcus voltae~~]]	+	[[Category: Atcc 33273]]
	[[Category: Fodje, M N]]		[[Category: Fodje, M N]]
	[[Category: Grochulski, P]]		[[Category: Grochulski, P]]

OCA at 01:56, 25 December 2014

OCA — Thu, 25 Dec 2014 01:56:51 GMT

←Older revision		Revision as of 01:56, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>		<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 Methanococcus voltae])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 Methanococcus voltae])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [http://www.ebi.ac.uk/pdbsum/2i1q PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [http://www.ebi.ac.uk/pdbsum/2i1q PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RADA_METVO RADA_METVO]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Methanococcus voltae]]		[[Category: Methanococcus voltae]]
-	[[Category: Fodje, M N.]]	+	[[Category: Fodje, M N]]
-	[[Category: Grochulski, P.]]	+	[[Category: Grochulski, P]]
-	[[Category: He, Y.]]	+	[[Category: He, Y]]
-	[[Category: Luo, Y.]]	+	[[Category: Luo, Y]]
-	[[Category: Ma, X.]]	+	[[Category: Ma, X]]
-	[[Category: Qian, X.]]	+	[[Category: Qian, X]]
	[[Category: Atp complex]]		[[Category: Atp complex]]
	[[Category: Atpase]]		[[Category: Atpase]]

OCA at 05:48, 29 September 2014

OCA — Mon, 29 Sep 2014 05:48:50 GMT

←Older revision		Revision as of 05:48, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2i1q.~~png~~\|~~left~~\|200px]]	+	==RadA Recombinase in complex with Calcium==
		+	<StructureSection load='2i1q' size='340' side='right' caption='[[2i1q]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2i1q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I1Q FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z4d\|1z4d]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">RADA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2188 Methanococcus voltae])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i1q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i1q RCSB], [http://www.ebi.ac.uk/pdbsum/2i1q PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/2i1q_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Archaeal RadA or Rad51 recombinases are close homologues of eukaryal Rad51 and DMC1. These and bacterial RecA orthologues play a key role in DNA repair by forming helical nucleoprotein filaments in which a hallmark strand exchange reaction between homologous DNA substrates occurs. Recent studies have discovered the stimulatory role by calcium on human and yeast recombinases. Here we report that the strand exchange activity but not the ATPase activity of an archaeal RadA/Rad51 recombinase from Methanococcus voltae (MvRadA) is also subject to calcium stimulation. Crystallized MvRadA filaments in the presence of CaCl(2) resemble that of the recently reported ATPase active form in the presence of an activating dose of KCl. At the ATPase center, one Ca(2+) ion takes the place of two K(+) ions in the K(+)-bound form. The terminal phosphate of the nonhydrolyzable ATP analogue is in a staggered conformation in the Ca(2+)-bound form. In comparison, an eclipsed conformation was seen in the K(+)-bound form. Despite the changes in the ATPase center, both forms harbor largely ordered L2 regions in essentially identical conformations. These data suggest a unified stimulation mechanism by potassium and calcium because of the existence of a conserved ATPase center promiscuous in binding cations.

-	~~{{STRUCTURE_2i1q\| PDB=2i1q \| SCENE= }}~~	+	Calcium stiffens archaeal Rad51 recombinase from Methanococcus voltae for homologous recombination.,Qian X, He Y, Ma X, Fodje MN, Grochulski P, Luo Y J Biol Chem. 2006 Dec 22;281(51):39380-7. Epub 2006 Oct 17. PMID:17050545<ref>PMID:17050545</ref>

-	~~===RadA Recombinase in complex with Calcium===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17050545}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2i1q]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Methanococcus_voltae Methanococcus voltae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA].~~	+

	==See Also==		==See Also==
	*[[Resolvase\|Resolvase]]		*[[Resolvase\|Resolvase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017050545<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Methanococcus voltae]]		[[Category: Methanococcus voltae]]
	[[Category: Fodje, M N.]]		[[Category: Fodje, M N.]]

OCA at 11:23, 20 October 2012

OCA — Sat, 20 Oct 2012 11:23:11 GMT

←Older revision		Revision as of 11:23, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2i1q]] is a 1 chain structure ~~of [[Resolvase]]~~ with sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA].	+	[[2i1q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA].

	==See Also==		==See Also==

OCA: Protected "2i1q" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 05:10:55 GMT

Protected "2i1q" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:10, 26 July 2012

OCA at 05:10, 26 July 2012

OCA — Thu, 26 Jul 2012 05:10:54 GMT

←Older revision		Revision as of 05:10, 26 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2i1q.png\|left\|200px]]		[[Image:2i1q.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2i1q", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2i1q\| PDB=2i1q \| SCENE= }}		{{STRUCTURE_2i1q\| PDB=2i1q \| SCENE= }}

	===RadA Recombinase in complex with Calcium===		===RadA Recombinase in complex with Calcium===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17050545}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17050545 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17050545}}		{{ABSTRACT_PUBMED_17050545}}

	==About this Structure==		==About this Structure==
-	~~2I1Q~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA].	+	[[2i1q]] is a 1 chain structure of [[Resolvase]] with sequence from [http://en.wikipedia.org/wiki/Methanococcus_voltae Methanococcus voltae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1Q OCA].
		+
		+	==See Also==
		+	*[[Resolvase\|Resolvase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17050545~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017050545</ref><references group="xtra"/>
	[[Category: Methanococcus voltae]]		[[Category: Methanococcus voltae]]
	[[Category: Fodje, M N.]]		[[Category: Fodje, M N.]]
Line 40:		Line 31:
	[[Category: Recombinase]]		[[Category: Recombinase]]
	[[Category: Recombination]]		[[Category: Recombination]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Apr 19 08:42:20 2009''