2i21 - Revision history

OCA at 10:05, 30 August 2023

OCA — Wed, 30 Aug 2023 10:05:09 GMT

←Older revision		Revision as of 10:05, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='2i21' size='340' side='right'caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>		<StructureSection load='2i21' size='340' side='right'caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I21 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I21 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.84Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [https://pdbe.org/2i21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [https://www.ebi.ac.uk/pdbsum/2i21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i21 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [https://pdbe.org/2i21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [https://www.ebi.ac.uk/pdbsum/2i21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i21 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.	+	[https://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA] Light-driven proton pump.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus halobius ruber klebahn 1919~~]]	+	[[Category: Halobacterium salinarum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Lanyi~~, J K~~]]	+	[[Category: Lanyi JK]]
-	[[Category: Schobert, B]]	+	[[Category: Schobert B]]
-	~~[[Category: 7-transmembrane]]~~	+
-	~~[[Category: Haloarchaea]]~~	+
-	~~[[Category: Ion pump]]~~	+
-	~~[[Category: Ion transport]]~~	+
-	~~[[Category: Lipid]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Photoreceptor]]~~	+
-	~~[[Category: Retinal protein]]~~	+
-	~~[[Category: Serpentine]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 17:49, 20 October 2021

OCA — Wed, 20 Oct 2021 17:49:08 GMT

←Older revision		Revision as of 17:49, 20 October 2021
Line 3:		Line 3:
	<StructureSection load='2i21' size='340' side='right'caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>		<StructureSection load='2i21' size='340' side='right'caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2I21 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2I21 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [~~http~~://pdbe.org/2i21 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2i21 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2i21 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [https://pdbe.org/2i21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [https://www.ebi.ac.uk/pdbsum/2i21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2i21 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.	+	[[https://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:41, 8 April 2020

OCA — Wed, 08 Apr 2020 07:41:31 GMT

←Older revision		Revision as of 07:41, 8 April 2020
Line 1:		Line 1:

	==Bacteriorhodopsin/lipid complex, T46V mutant==		==Bacteriorhodopsin/lipid complex, T46V mutant==
-	<StructureSection load='2i21' size='340' side='right' caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>	+	<StructureSection load='2i21' size='340' side='right'caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2I21 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2I21 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://pdbe.org/2i21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2i21 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://pdbe.org/2i21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2i21 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Bacteriorhodopsin\|Bacteriorhodopsin]]	+	*[[Bacteriorhodopsin 3D structures\|Bacteriorhodopsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus halobius ruber klebahn 1919]]		[[Category: Bacillus halobius ruber klebahn 1919]]
		+	[[Category: Large Structures]]
	[[Category: Lanyi, J K]]		[[Category: Lanyi, J K]]
	[[Category: Schobert, B]]		[[Category: Schobert, B]]

OCA at 07:55, 4 July 2018

OCA — Wed, 04 Jul 2018 07:55:55 GMT

←Older revision		Revision as of 07:55, 4 July 2018
Line 1:		Line 1:
		+
	==Bacteriorhodopsin/lipid complex, T46V mutant==		==Bacteriorhodopsin/lipid complex, T46V mutant==
	<StructureSection load='2i21' size='340' side='right' caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>		<StructureSection load='2i21' size='340' side='right' caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I21 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I21 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://pdbe.org/2i21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://pdbe.org/2i21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2i21 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/2i21_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/2i21_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:15, 9 February 2016

OCA — Tue, 09 Feb 2016 02:15:32 GMT

←Older revision		Revision as of 02:15, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2i21 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:37, 10 September 2015

OCA — Thu, 10 Sep 2015 17:37:32 GMT

←Older revision		Revision as of 17:37, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2i21' size='340' side='right' caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>		<StructureSection load='2i21' size='340' side='right' caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Halobacterium_salinarum Halobacterium salinarum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I21 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_halobius_ruber"_klebahn_1919 "bacillus halobius ruber" klebahn 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I21 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://pdbe.org/2i21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2i21" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Halobacterium salinarum~~]]	+	[[Category: Bacillus halobius ruber klebahn 1919]]
	[[Category: Lanyi, J K]]		[[Category: Lanyi, J K]]
	[[Category: Schobert, B]]		[[Category: Schobert, B]]

OCA at 03:43, 25 December 2014

OCA — Thu, 25 Dec 2014 03:43:10 GMT

←Older revision		Revision as of 03:43, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I21 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I21 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BACR_HALSA BACR_HALSA]] Light-driven proton pump.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Halobacterium salinarum]]		[[Category: Halobacterium salinarum]]
-	[[Category: Lanyi, J K.]]	+	[[Category: Lanyi, J K]]
-	[[Category: Schobert, B.]]	+	[[Category: Schobert, B]]
	[[Category: 7-transmembrane]]		[[Category: 7-transmembrane]]
	[[Category: Haloarchaea]]		[[Category: Haloarchaea]]

OCA at 03:22, 29 September 2014

OCA — Mon, 29 Sep 2014 03:22:04 GMT

←Older revision		Revision as of 03:22, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2i21.~~png\|left~~\|200px]]	+	==Bacteriorhodopsin/lipid complex, T46V mutant==
		+	<StructureSection load='2i21' size='340' side='right' caption='[[2i21]], [[Resolution\|resolution]] 1.84Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2I21 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LI1:1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL'>LI1</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene>, <scene name='pdbligand=SQU:2,10,23-TRIMETHYL-TETRACOSANE'>SQU</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2i21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2i21 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2i21 RCSB], [http://www.ebi.ac.uk/pdbsum/2i21 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/2i21_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The X-ray diffraction structure of the non-illuminated D96A bacteriorhodopsin mutant reveals structural changes as far away as 15 A from residue 96, at the retinal, Trp-182, Ala-215, and waters 501, 402, and 401. The Asp-to-Ala side-chain replacement breaks its hydrogen bond with Thr-46, and the resulting separation of the cytoplasmic ends of helices B and C is communicated to the retinal region through a chain of covalent and hydrogen bonds. The unexpected long-range consequences of the D96A mutation include breaking the hydrogen bond between O of Ala-215 and water 501 and the formation of a new hydrogen bond between water molecules 401 and 402 in the extracellular region. Because in the T46V mutant a new water molecule appears at Asp-96 and its hydrogen-bond to Ile-45 replaces Thr-46 as its link to helix B, the separation of helices B and C is smaller than that in D96A, and there are no atomic displacements elsewhere in the protein. Propagation of conformational changes along the chain between the retinal and Thr-46 had been observed earlier in the crystal structures of the D96N and E204Q mutants but in the trapped M state. Consistent with the perturbation of the retinal region in D96A, little change of the Thr-46 region occurs between the non-illuminated and M states of this mutant. It appears that a local perturbation can propagate along a track in both directions between the retinal and the Asp-96/Thr-46 pair, either from photoisomerization of the retinal in the wild-type protein in one case or from the D96A mutation in the other.

-	~~{{STRUCTURE_2i21\| PDB=2i21 \| SCENE= }}~~	+	Propagating structural perturbation inside bacteriorhodopsin: crystal structures of the M state and the D96A and T46V mutants.,Lanyi JK, Schobert B Biochemistry. 2006 Oct 3;45(39):12003-10. PMID:17002299<ref>PMID:17002299</ref>

-	~~===Bacteriorhodopsin~~/~~lipid complex~~, ~~T46V mutant===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17002299}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2i21]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Halobacterium_salinarum Halobacterium salinarum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA].~~	+

	==See Also==		==See Also==
	*[[Bacteriorhodopsin\|Bacteriorhodopsin]]		*[[Bacteriorhodopsin\|Bacteriorhodopsin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017002299<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Halobacterium salinarum]]		[[Category: Halobacterium salinarum]]
	[[Category: Lanyi, J K.]]		[[Category: Lanyi, J K.]]

OCA at 12:17, 20 October 2012

OCA — Sat, 20 Oct 2012 12:17:53 GMT

←Older revision		Revision as of 12:17, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2i21]] is a 1 chain structure ~~of [[Bacteriorhodopsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA].	+	[[2i21]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_salinarum Halobacterium salinarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I21 OCA].

	==See Also==		==See Also==

OCA: Protected "2i21" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 08:16:43 GMT

Protected "2i21" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:16, 26 July 2012