2ixs - Revision history

OCA at 09:31, 9 May 2024

OCA — Thu, 09 May 2024 09:31:50 GMT

←Older revision		Revision as of 09:31, 9 May 2024
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	<StructureSection load='2ixs' size='340' side='right'caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ixs' size='340' side='right'caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"actinomyces_diastaticus"_krainsky_1914 "actinomyces~~ diastaticus~~" krainsky 1914~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IXS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IXS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [https://pdbe.org/2ixs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [https://www.ebi.ac.uk/pdbsum/2ixs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ixs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [https://pdbe.org/2ixs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [https://www.ebi.ac.uk/pdbsum/2ixs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ixs ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/C4P954_STRDI C4P954_STRDI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Actinomyces diastaticus krainsky 1914]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Type II site-specific deoxyribonuclease~~]]	+	[[Category: Streptomyces diastaticus]]
-	[[Category: Grazulis, S]]	+	[[Category: Grazulis S]]
-	[[Category: Huber, R]]	+	[[Category: Huber R]]
-	[[Category: Jakubauskas, A]]	+	[[Category: Jakubauskas A]]
-	[[Category: Siksnys, V]]	+	[[Category: Siksnys V]]
-	[[Category: Tamulaitiene, G]]	+	[[Category: Tamulaitiene G]]
-	[[Category: Urbanke, C]]	+	[[Category: Urbanke C]]
-	~~[[Category: Domain architecture]]~~	+
-	~~[[Category: Endonuclease]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Restriction endonuclease]]~~	+
-	~~[[Category: Sdai~~]]	+

OCA at 07:56, 19 January 2022

OCA — Wed, 19 Jan 2022 07:56:36 GMT

←Older revision		Revision as of 07:56, 19 January 2022
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	<StructureSection load='2ixs' size='340' side='right'caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ixs' size='340' side='right'caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"actinomyces_diastaticus"_krainsky_1914 "actinomyces diastaticus" krainsky 1914]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2IXS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinomyces_diastaticus"_krainsky_1914 "actinomyces diastaticus" krainsky 1914]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IXS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [~~http~~://pdbe.org/2ixs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ixs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ixs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [https://pdbe.org/2ixs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [https://www.ebi.ac.uk/pdbsum/2ixs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ixs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:34, 15 April 2020

OCA — Wed, 15 Apr 2020 07:34:19 GMT

←Older revision		Revision as of 07:34, 15 April 2020
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	==Structure of SdaI restriction endonuclease==		==Structure of SdaI restriction endonuclease==
-	<StructureSection load='2ixs' size='340' side='right' caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='2ixs' size='340' side='right'caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_diastaticus"_krainsky_1914 "actinomyces diastaticus" krainsky 1914]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2IXS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_diastaticus"_krainsky_1914 "actinomyces diastaticus" krainsky 1914]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2IXS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://pdbe.org/2ixs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ixs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://pdbe.org/2ixs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ixs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Endonuclease\|Endonuclease]]	+	*[[Endonuclease 3D structures\|Endonuclease 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Actinomyces diastaticus krainsky 1914]]		[[Category: Actinomyces diastaticus krainsky 1914]]
		+	[[Category: Large Structures]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]
	[[Category: Grazulis, S]]		[[Category: Grazulis, S]]

OCA at 07:21, 11 July 2018

OCA — Wed, 11 Jul 2018 07:21:49 GMT

←Older revision		Revision as of 07:21, 11 July 2018
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-	==~~STRUCTURE OF SDAI RESTRICTION ENDONUCLEASE~~==	+
		+	==Structure of SdaI restriction endonuclease==
	<StructureSection load='2ixs' size='340' side='right' caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ixs' size='340' side='right' caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://pdbe.org/2ixs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://pdbe.org/2ixs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ixs ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/2ixs_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/2ixs_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ixs ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:21, 11 September 2015

OCA — Fri, 11 Sep 2015 07:21:34 GMT

←Older revision		Revision as of 07:21, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2ixs' size='340' side='right' caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='2ixs' size='340' side='right' caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_diastaticus Streptomyces~~ diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IXS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_diastaticus"_krainsky_1914 "actinomyces diastaticus" krainsky 1914]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IXS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://pdbe.org/2ixs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ixs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Streptomyces~~ diastaticus]]	+	[[Category: Actinomyces diastaticus krainsky 1914]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]
	[[Category: Grazulis, S]]		[[Category: Grazulis, S]]

OCA at 18:42, 19 January 2015

OCA — Mon, 19 Jan 2015 18:42:29 GMT

←Older revision		Revision as of 18:42, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IXS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IXS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	[[Category: Streptomyces diastaticus]]		[[Category: Streptomyces diastaticus]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]
-	[[Category: Grazulis, S.]]	+	[[Category: Grazulis, S]]
-	[[Category: Huber, R.]]	+	[[Category: Huber, R]]
-	[[Category: Jakubauskas, A.]]	+	[[Category: Jakubauskas, A]]
-	[[Category: Siksnys, V.]]	+	[[Category: Siksnys, V]]
-	[[Category: Tamulaitiene, G.]]	+	[[Category: Tamulaitiene, G]]
-	[[Category: Urbanke, C.]]	+	[[Category: Urbanke, C]]
	[[Category: Domain architecture]]		[[Category: Domain architecture]]
	[[Category: Endonuclease]]		[[Category: Endonuclease]]

OCA at 04:21, 29 September 2014

OCA — Mon, 29 Sep 2014 04:21:10 GMT

←Older revision		Revision as of 04:21, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2ixs.~~png\|left~~\|200px]]	+	==STRUCTURE OF SDAI RESTRICTION ENDONUCLEASE==
		+	<StructureSection load='2ixs' size='340' side='right' caption='[[2ixs]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IXS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ixs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ixs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ixs RCSB], [http://www.ebi.ac.uk/pdbsum/2ixs PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ix/2ixs_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rare-cutting restriction enzymes are important tools in genome analysis. We report here the crystal structure of SdaI restriction endonuclease, which is specific for the 8 bp sequence CCTGCA/GG ("/" designates the cleavage site). Unlike orthodox Type IIP enzymes, which are single domain proteins, the SdaI monomer is composed of two structural domains. The N domain contains a classical winged helix-turn-helix (wHTH) DNA binding motif, while the C domain shows a typical restriction endonuclease fold. The active site of SdaI is located within the C domain and represents a variant of the canonical PD-(D/E)XK motif. SdaI determinants of sequence specificity are clustered on the recognition helix of the wHTH motif at the N domain. The modular architecture of SdaI, wherein one domain mediates DNA binding while the other domain is predicted to catalyze hydrolysis, distinguishes SdaI from previously characterized restriction enzymes interacting with symmetric recognition sequences.

-	~~{{STRUCTURE_2ixs\| PDB=2ixs \| SCENE= }}~~	+	The crystal structure of the rare-cutting restriction enzyme SdaI reveals unexpected domain architecture.,Tamulaitiene G, Jakubauskas A, Urbanke C, Huber R, Grazulis S, Siksnys V Structure. 2006 Sep;14(9):1389-400. PMID:16962970<ref>PMID:16962970</ref>

-	~~===STRUCTURE OF SDAI RESTRICTION ENDONUCLEASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_16962970}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2ixs]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA].~~	+

	==See Also==		==See Also==
	*[[Endonuclease\|Endonuclease]]		*[[Endonuclease\|Endonuclease]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:016962970<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Streptomyces diastaticus]]		[[Category: Streptomyces diastaticus]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]

OCA at 17:04, 20 October 2012

OCA — Sat, 20 Oct 2012 17:04:03 GMT

←Older revision		Revision as of 17:04, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2ixs]] is a 2 chain structure ~~of [[Endonuclease]]~~ with sequence from [http://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA].	+	[[2ixs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA].

	==See Also==		==See Also==

OCA: Protected "2ixs" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 23:43:08 GMT

Protected "2ixs" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:43, 26 July 2012

OCA at 23:43, 26 July 2012

OCA — Thu, 26 Jul 2012 23:43:07 GMT

←Older revision		Revision as of 23:43, 26 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2ixs.png\|left\|200px]]		[[Image:2ixs.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2ixs", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2ixs\| PDB=2ixs \| SCENE= }}		{{STRUCTURE_2ixs\| PDB=2ixs \| SCENE= }}

	===STRUCTURE OF SDAI RESTRICTION ENDONUCLEASE===		===STRUCTURE OF SDAI RESTRICTION ENDONUCLEASE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_16962970}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 16962970 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_16962970}}		{{ABSTRACT_PUBMED_16962970}}

	==About this Structure==		==About this Structure==
-	~~2IXS~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA].	+	[[2ixs]] is a 2 chain structure of [[Endonuclease]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_diastaticus Streptomyces diastaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXS OCA].
		+
		+	==See Also==
		+	*[[Endonuclease\|Endonuclease]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~16962970~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:016962970</ref><references group="xtra"/>
	[[Category: Streptomyces diastaticus]]		[[Category: Streptomyces diastaticus]]
	[[Category: Type II site-specific deoxyribonuclease]]		[[Category: Type II site-specific deoxyribonuclease]]
Line 37:		Line 28:
	[[Category: Restriction endonuclease]]		[[Category: Restriction endonuclease]]
	[[Category: Sdai]]		[[Category: Sdai]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:02:36 2009''