2iy4 - Revision history

OCA at 14:29, 13 December 2023

OCA — Wed, 13 Dec 2023 14:29:23 GMT

←Older revision		Revision as of 14:29, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='2iy4' size='340' side='right'caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='2iy4' size='340' side='right'caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium~~ monocytogenes ~~hominis" nyfeldt 1932~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.31Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [https://pdbe.org/2iy4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [https://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [https://pdbe.org/2iy4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [https://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DPS_LISMO DPS_LISMO]] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Does not bind to DNA (By similarity). Dps is important for full resistance to heat and cold shocks and is essential for full virulence of this bacterium. It seems to play a direct or indirect role on the production and/or stability of listeriolysin O.<ref>PMID:12383509</ref> <ref>PMID:15758237</ref> <ref>PMID:16098690</ref>	+	[https://www.uniprot.org/uniprot/DPS_LISMO DPS_LISMO] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Does not bind to DNA (By similarity). Dps is important for full resistance to heat and cold shocks and is essential for full virulence of this bacterium. It seems to play a direct or indirect role on the production and/or stability of listeriolysin O.<ref>PMID:12383509</ref> <ref>PMID:15758237</ref> <ref>PMID:16098690</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bellapadrona, G]]	+	[[Category: Listeria monocytogenes]]
-	[[Category: Chiancone, E]]	+	[[Category: Bellapadrona G]]
-	[[Category: Ilari, A]]	+	[[Category: Chiancone E]]
-	[[Category: Stefanini, S]]	+	[[Category: Ilari A]]
-	~~[[Category: Iron]]~~	+	[[Category: Stefanini S]]
-	~~[[Category: Iron storage]]~~	+
-	~~[[Category: Metal binding protein]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Metal-binding protein]]~~	+
-	~~[[Category: Oxidative damage~~]]	+

OCA at 07:56, 19 January 2022

OCA — Wed, 19 Jan 2022 07:56:40 GMT

←Older revision		Revision as of 07:56, 19 January 2022
Line 3:		Line 3:
	<StructureSection load='2iy4' size='340' side='right'caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='2iy4' size='340' side='right'caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [~~http~~://pdbe.org/2iy4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [https://pdbe.org/2iy4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [https://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DPS_LISMO DPS_LISMO]] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Does not bind to DNA (By similarity). Dps is important for full resistance to heat and cold shocks and is essential for full virulence of this bacterium. It seems to play a direct or indirect role on the production and/or stability of listeriolysin O.<ref>PMID:12383509</ref> <ref>PMID:15758237</ref> <ref>PMID:16098690</ref>	+	[[https://www.uniprot.org/uniprot/DPS_LISMO DPS_LISMO]] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Does not bind to DNA (By similarity). Dps is important for full resistance to heat and cold shocks and is essential for full virulence of this bacterium. It seems to play a direct or indirect role on the production and/or stability of listeriolysin O.<ref>PMID:12383509</ref> <ref>PMID:15758237</ref> <ref>PMID:16098690</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:34, 15 April 2020

OCA — Wed, 15 Apr 2020 07:34:26 GMT

←Older revision		Revision as of 07:34, 15 April 2020
Line 1:		Line 1:

	==X-ray structure of Dps from Listeria monocytogenes==		==X-ray structure of Dps from Listeria monocytogenes==
-	<StructureSection load='2iy4' size='340' side='right' caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>	+	<StructureSection load='2iy4' size='340' side='right'caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://pdbe.org/2iy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://pdbe.org/2iy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Ferritin\|Ferritin]]	+	*[[Ferritin 3D structures\|Ferritin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]		[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
		+	[[Category: Large Structures]]
	[[Category: Bellapadrona, G]]		[[Category: Bellapadrona, G]]
	[[Category: Chiancone, E]]		[[Category: Chiancone, E]]

OCA at 06:34, 11 July 2018

OCA — Wed, 11 Jul 2018 06:34:26 GMT

←Older revision		Revision as of 06:34, 11 July 2018
Line 1:		Line 1:
-	==X-~~RAY STRUCTURE OF DPS FROM LISTERIA MONOCYTOGENES~~==	+
		+	==X-ray structure of Dps from Listeria monocytogenes==
	<StructureSection load='2iy4' size='340' side='right' caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='2iy4' size='340' side='right' caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://pdbe.org/2iy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://pdbe.org/2iy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2iy4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/2iy4_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/2iy4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iy4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 41:		Line 42:
	[[Category: Iron]]		[[Category: Iron]]
	[[Category: Iron storage]]		[[Category: Iron storage]]
		+	[[Category: Metal binding protein]]
	[[Category: Metal-binding]]		[[Category: Metal-binding]]
	[[Category: Metal-binding protein]]		[[Category: Metal-binding protein]]
	[[Category: Oxidative damage]]		[[Category: Oxidative damage]]

OCA at 09:03, 11 September 2015

OCA — Fri, 11 Sep 2015 09:03:16 GMT

←Older revision		Revision as of 09:03, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2iy4' size='340' side='right' caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>		<StructureSection load='2iy4' size='340' side='right' caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Listeria_monocytogenes Listeria~~ monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_monocytogenes_hominis"_nyfeldt_1932 "bacterium monocytogenes hominis" nyfeldt 1932]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://pdbe.org/2iy4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DPS_LISMO DPS_LISMO]] Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Does not bind to DNA (By similarity). Dps is important for full resistance to heat and cold shocks and is essential for full virulence of this bacterium. It seems to play a direct or indirect role on the production and/or stability of listeriolysin O.<ref>PMID:12383509</ref> <ref>PMID:15758237</ref> <ref>PMID:16098690</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2iy4" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Listeria~~ monocytogenes]]	+	[[Category: Bacterium monocytogenes hominis nyfeldt 1932]]
	[[Category: Bellapadrona, G]]		[[Category: Bellapadrona, G]]
	[[Category: Chiancone, E]]		[[Category: Chiancone, E]]

OCA at 16:19, 19 January 2015

OCA — Mon, 19 Jan 2015 16:19:49 GMT

←Older revision		Revision as of 16:19, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Listeria monocytogenes]]		[[Category: Listeria monocytogenes]]
-	[[Category: Bellapadrona, G.]]	+	[[Category: Bellapadrona, G]]
-	[[Category: Chiancone, E.]]	+	[[Category: Chiancone, E]]
-	[[Category: Ilari, A.]]	+	[[Category: Ilari, A]]
-	[[Category: Stefanini, S.]]	+	[[Category: Stefanini, S]]
	[[Category: Iron]]		[[Category: Iron]]
	[[Category: Iron storage]]		[[Category: Iron storage]]

OCA at 05:32, 29 September 2014

OCA — Mon, 29 Sep 2014 05:32:28 GMT

←Older revision		Revision as of 05:32, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2iy4.~~png\|left~~\|200px]]	+	==X-RAY STRUCTURE OF DPS FROM LISTERIA MONOCYTOGENES==
		+	<StructureSection load='2iy4' size='340' side='right' caption='[[2iy4]], [[Resolution\|resolution]] 2.31Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IY4 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/2iy4 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/2iy4_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The stability of the dodecameric Listeria monocytogenes Dps has been compared with that of the Listeria innocua protein. The two proteins differ only in two amino acid residues that form an intersubunit salt-bridge in L. innocua Dps. This salt-bridge is replaced by a hydrogen bonding network in L. monocytogenes Dps as revealed by the X-ray crystal structure. The resistance to low pH and high temperature was assayed for both Dps proteins under equilibrium conditions and kinetically. Despite the identical equilibrium behavior, significant differences in the kinetic stability and activation energy of the unfolding process are apparent at pH 1.5. The higher stability of L. monocytogenes Dps has been accounted for in terms of the persistence of the hydrogen bonding network at this low pH value. In contrast, the salt-bridge between Lys 114 and Asp 126 characteristic of L. innocua Dps is most likely abolished due to protonation of Asp 126.

-	~~{{STRUCTURE_2iy4\| PDB=2iy4 \| SCENE= }}~~	+	The mutations Lys 114 --> Gln and Asp 126 --> Asn disrupt an intersubunit salt bridge and convert Listeria innocua Dps into its natural mutant Listeria monocytogenes Dps. Effects on protein stability at Low pH.,Bellapadrona G, Chiaraluce R, Consalvi V, Ilari A, Stefanini S, Chiancone E Proteins. 2007 Mar 1;66(4):975-83. PMID:17186524<ref>PMID:17186524</ref>

-	~~===X-RAY STRUCTURE OF DPS FROM LISTERIA MONOCYTOGENES===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17186524}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2iy4]] is~~ a ~~24 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Listeria_monocytogenes Listeria monocytogenes]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA].~~	+

	==See Also==		==See Also==
	*[[Ferritin\|Ferritin]]		*[[Ferritin\|Ferritin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017186524<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Listeria monocytogenes]]		[[Category: Listeria monocytogenes]]
	[[Category: Bellapadrona, G.]]		[[Category: Bellapadrona, G.]]

OCA at 17:41, 20 October 2012

OCA — Sat, 20 Oct 2012 17:41:27 GMT

←Older revision		Revision as of 17:41, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2iy4]] is a 24 chain structure ~~of [[Ferritin]]~~ with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA].	+	[[2iy4]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IY4 OCA].

	==See Also==		==See Also==

OCA at 01:42, 27 July 2012

OCA — Fri, 27 Jul 2012 01:42:34 GMT

←Older revision		Revision as of 01:42, 27 July 2012
Line 1:		Line 1:
	[[Image:2iy4.png\|left\|200px]]		[[Image:2iy4.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2iy4", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2iy4\| PDB=2iy4 \| SCENE= }}		{{STRUCTURE_2iy4\| PDB=2iy4 \| SCENE= }}

	===X-RAY STRUCTURE OF DPS FROM LISTERIA MONOCYTOGENES===		===X-RAY STRUCTURE OF DPS FROM LISTERIA MONOCYTOGENES===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17186524}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17186524 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17186524}}		{{ABSTRACT_PUBMED_17186524}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Ferritin]]	+	*[[Ferritin\|Ferritin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17186524~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017186524</ref><references group="xtra"/>
	[[Category: Listeria monocytogenes]]		[[Category: Listeria monocytogenes]]
	[[Category: Bellapadrona, G.]]		[[Category: Bellapadrona, G.]]

OCA: Protected "2iy4" [edit=sysop:move=sysop]

OCA — Mon, 27 Dec 2010 02:19:58 GMT

Protected "2iy4" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:19, 27 December 2010