2izn - Revision history

OCA at 06:41, 1 May 2024

OCA — Wed, 01 May 2024 06:41:24 GMT

←Older revision		Revision as of 06:41, 1 May 2024
Line 3:		Line 3:
	<StructureSection load='2izn' size='340' side='right'caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='2izn' size='340' side='right'caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacteriophage_ms2 Bacteriophage ms2~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZN FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1aq3\|1aq3]]~~, [[~~1aq4~~\|~~1aq4~~]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</div></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.56Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [https://pdbe.org/2izn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [https://www.ebi.ac.uk/pdbsum/2izn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [https://pdbe.org/2izn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [https://www.ebi.ac.uk/pdbsum/2izn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~COAT_BPMS2 COAT_BPMS2~~]~~] Forms~~ the ~~phage~~ shell~~; binds~~ to the ~~phage~~ RNA.	+	[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2izn ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2izn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We have determined the structures of complexes between the phage MS2 coat protein and variants of the replicase translational operator in order to explore the sequence specificity of the RNA-protein interaction. The 19-nt RNA hairpins studied have substitutions at two positions that have been shown to be important for specific binding. At one of these positions, -10, which is a bulged adenosine (A) in the stem of the wild-type operator hairpin, substitutions were made with guanosine (G), cytidine (C) and two non-native bases, 2-aminopurine (2AP) and inosine (I). At the other position, -7 in the hairpin loop, the native adenine was substituted with a cytidine. Of these, only the G-10, C-10 and C-7 variants showed interpretable density for the RNA hairpin. In spite of large differences in binding affinities, the structures of the variant complexes are very similar to the wild-type operator complex. For G-10 substitutions in hairpin variants that can form bulges at alternative places in the stem, the binding affinity is low and a partly disordered conformation is seen in the electron density maps. The affinity is similar to that of wild-type when the base pairs adjacent to the bulged nucleotide are selected to avoid alternative conformations. Both purines bind in a very similar way in a pocket in the protein. In the C-10 variant, which has very low affinity, the cytidine is partly inserted in the protein pocket rather than intercalated in the RNA stem. Substitution of the wild-type adenosine at position -7 by pyrimidines gives strongly reduced affinities, but the structure of the C-7 complex shows that the base occupies the same position as the A-7 in the wild-type RNA. It is stacked in the RNA and makes no direct contact with the protein.

-	Investigating the structural basis of purine specificity in the structures of MS2 coat protein RNA translational operator hairpins.,Helgstrand C, Grahn E, Moss T, Stonehouse NJ, Tars K, Stockley PG, Liljas L Nucleic Acids Res. 2002 Jun 15;30(12):2678-85. PMID:12060685<ref>PMID:12060685</ref>	+	==See Also==
-		+	*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class~~=~~"pdbe-citations 2izn" style~~=~~"background-color:#fffaf0;"></div>~~	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacteriophage ms2~~]]	+	[[Category: Escherichia phage MS2]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Grahn, E]]	+	[[Category: Grahn E]]
-	[[Category: Helgstrand, C]]	+	[[Category: Helgstrand C]]
-	[[Category: Liljas, L]]	+	[[Category: Liljas L]]
-	[[Category: Moss, T]]	+	[[Category: Moss T]]
-	[[Category: Stockley~~, P G~~]]	+	[[Category: Stockley PG]]
-	[[Category: Stonehouse~~, N J~~]]	+	[[Category: Stonehouse NJ]]
-	[[Category: Tars, K]]	+	[[Category: Tars K]]
-	~~[[Category: Capsid]]~~	+
-	~~[[Category: Capsid protein]]~~	+
-	~~[[Category: Hairpin]]~~	+
-	~~[[Category: Levivirus]]~~	+
-	~~[[Category: Rna-binding]]~~	+
-	~~[[Category: Structural protein]]~~	+
-	~~[[Category: Virus]]~~	+
-	~~[[Category: Virus-rna complex]]~~	+
-	~~[[Category: Virus/rna]]~~	+
-	~~[[Category: Virus/viral protein/rna~~]]	+

OCA at 07:57, 19 January 2022

OCA — Wed, 19 Jan 2022 07:57:52 GMT

←Older revision		Revision as of 07:57, 19 January 2022
Line 3:		Line 3:
	<StructureSection load='2izn' size='340' side='right'caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='2izn' size='340' side='right'caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2IZN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZN FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [~~http~~://pdbe.org/2izn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2izn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2izn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [https://pdbe.org/2izn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [https://www.ebi.ac.uk/pdbsum/2izn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.	+	[[https://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:35, 15 April 2020

OCA — Wed, 15 Apr 2020 07:35:38 GMT

←Older revision		Revision as of 07:35, 15 April 2020
Line 1:		Line 1:

	==MS2-RNA HAIRPIN (G-10) COMPLEX==		==MS2-RNA HAIRPIN (G-10) COMPLEX==
-	<StructureSection load='2izn' size='340' side='right' caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>	+	<StructureSection load='2izn' size='340' side='right'caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2IZN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2IZN FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://pdbe.org/2izn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2izn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://pdbe.org/2izn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2izn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacteriophage ms2]]		[[Category: Bacteriophage ms2]]
		+	[[Category: Large Structures]]
	[[Category: Grahn, E]]		[[Category: Grahn, E]]
	[[Category: Helgstrand, C]]		[[Category: Helgstrand, C]]

OCA at 06:33, 11 July 2018

OCA — Wed, 11 Jul 2018 06:33:10 GMT

←Older revision		Revision as of 06:33, 11 July 2018
Line 1:		Line 1:
		+
	==MS2-RNA HAIRPIN (G-10) COMPLEX==		==MS2-RNA HAIRPIN (G-10) COMPLEX==
	<StructureSection load='2izn' size='340' side='right' caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='2izn' size='340' side='right' caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZN FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://pdbe.org/2izn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://pdbe.org/2izn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2izn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izn_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izn_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 07:21, 9 February 2016

OCA — Tue, 09 Feb 2016 07:21:05 GMT

←Older revision		Revision as of 07:21, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2izn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 19:55, 10 September 2015

OCA — Thu, 10 Sep 2015 19:55:03 GMT

←Older revision		Revision as of 19:55, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2izn' size='340' side='right' caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>		<StructureSection load='2izn' size='340' side='right' caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacterio_phage_ms2 Enterobacterio phage~~ ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZN FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://pdbe.org/2izn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2izn" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacterio phage~~ ms2]]	+	[[Category: Bacteriophage ms2]]
	[[Category: Grahn, E]]		[[Category: Grahn, E]]
	[[Category: Helgstrand, C]]		[[Category: Helgstrand, C]]

OCA at 05:18, 25 December 2014

OCA — Thu, 25 Dec 2014 05:18:51 GMT

←Older revision		Revision as of 05:18, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
-	[[Category: Grahn, E.]]	+	[[Category: Grahn, E]]
-	[[Category: Helgstrand, C.]]	+	[[Category: Helgstrand, C]]
-	[[Category: Liljas, L.]]	+	[[Category: Liljas, L]]
-	[[Category: Moss, T.]]	+	[[Category: Moss, T]]
-	[[Category: Stockley, P G.]]	+	[[Category: Stockley, P G]]
-	[[Category: Stonehouse, N J.]]	+	[[Category: Stonehouse, N J]]
-	[[Category: Tars, K.]]	+	[[Category: Tars, K]]
	[[Category: Capsid]]		[[Category: Capsid]]
	[[Category: Capsid protein]]		[[Category: Capsid protein]]

OCA at 10:39, 3 October 2014

OCA — Fri, 03 Oct 2014 10:39:10 GMT

←Older revision		Revision as of 10:39, 3 October 2014
Line 1:		Line 1:
-	[[~~Image:~~2izn.~~png~~\|~~left~~\|200px]]	+	==MS2-RNA HAIRPIN (G-10) COMPLEX==
		+	<StructureSection load='2izn' size='340' side='right' caption='[[2izn]], [[Resolution\|resolution]] 2.56Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZN FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aq3\|1aq3]], [[1aq4\|1aq4]], [[1bms\|1bms]], [[1msc\|1msc]], [[1mst\|1mst]], [[1mva\|1mva]], [[1mvb\|1mvb]], [[1u1y\|1u1y]], [[1zdh\|1zdh]], [[1zdi\|1zdi]], [[1zdj\|1zdj]], [[1zdk\|1zdk]], [[1zse\|1zse]], [[2b2d\|2b2d]], [[2b2e\|2b2e]], [[2b2g\|2b2g]], [[2bny\|2bny]], [[2bq5\|2bq5]], [[2bs0\|2bs0]], [[2bs1\|2bs1]], [[2bu1\|2bu1]], [[2c4q\|2c4q]], [[2c4y\|2c4y]], [[2c4z\|2c4z]], [[2c50\|2c50]], [[2c51\|2c51]], [[2ms2\|2ms2]], [[5msf\|5msf]], [[6msf\|6msf]], [[7msf\|7msf]], [[2iz8\|2iz8]], [[2iz9\|2iz9]], [[2izm\|2izm]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2izn RCSB], [http://www.ebi.ac.uk/pdbsum/2izn PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izn_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the structures of complexes between the phage MS2 coat protein and variants of the replicase translational operator in order to explore the sequence specificity of the RNA-protein interaction. The 19-nt RNA hairpins studied have substitutions at two positions that have been shown to be important for specific binding. At one of these positions, -10, which is a bulged adenosine (A) in the stem of the wild-type operator hairpin, substitutions were made with guanosine (G), cytidine (C) and two non-native bases, 2-aminopurine (2AP) and inosine (I). At the other position, -7 in the hairpin loop, the native adenine was substituted with a cytidine. Of these, only the G-10, C-10 and C-7 variants showed interpretable density for the RNA hairpin. In spite of large differences in binding affinities, the structures of the variant complexes are very similar to the wild-type operator complex. For G-10 substitutions in hairpin variants that can form bulges at alternative places in the stem, the binding affinity is low and a partly disordered conformation is seen in the electron density maps. The affinity is similar to that of wild-type when the base pairs adjacent to the bulged nucleotide are selected to avoid alternative conformations. Both purines bind in a very similar way in a pocket in the protein. In the C-10 variant, which has very low affinity, the cytidine is partly inserted in the protein pocket rather than intercalated in the RNA stem. Substitution of the wild-type adenosine at position -7 by pyrimidines gives strongly reduced affinities, but the structure of the C-7 complex shows that the base occupies the same position as the A-7 in the wild-type RNA. It is stacked in the RNA and makes no direct contact with the protein.

-	~~{{STRUCTURE_2izn\| PDB=2izn \| SCENE= }}~~	+	Investigating the structural basis of purine specificity in the structures of MS2 coat protein RNA translational operator hairpins.,Helgstrand C, Grahn E, Moss T, Stonehouse NJ, Tars K, Stockley PG, Liljas L Nucleic Acids Res. 2002 Jun 15;30(12):2678-85. PMID:12060685<ref>PMID:12060685</ref>

-	~~===MS2-RNA HAIRPIN (G-10) COMPLEX===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12060685}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2izn]] is~~ a ~~5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes~~ the ~~now removed PDB entry [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012060685<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Grahn, E.]]		[[Category: Grahn, E.]]

OCA: Protected "2izn" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 13:30:32 GMT

Protected "2izn" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:30, 7 January 2013

OCA at 13:30, 7 January 2013

OCA — Mon, 07 Jan 2013 13:30:29 GMT

←Older revision		Revision as of 13:30, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2izn.png\|left\|200px]]		[[Image:2izn.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2izn", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2izn\| PDB=2izn \| SCENE= }}		{{STRUCTURE_2izn\| PDB=2izn \| SCENE= }}

	===MS2-RNA HAIRPIN (G-10) COMPLEX===		===MS2-RNA HAIRPIN (G-10) COMPLEX===

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-	(as it appears on PubMed at http://www.pubmed.gov), where 12060685 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_12060685}}		{{ABSTRACT_PUBMED_12060685}}

	==About this Structure==		==About this Structure==
-	~~2IZN~~ is a 5 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA].	+	[[2izn]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gkw 1gkw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZN OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12060685~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012060685</ref><references group="xtra"/>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Grahn, E.]]		[[Category: Grahn, E.]]
Line 32:		Line 20:
	[[Category: Stonehouse, N J.]]		[[Category: Stonehouse, N J.]]
	[[Category: Tars, K.]]		[[Category: Tars, K.]]
-	[[Category: 3d-structure]]
	[[Category: Capsid]]		[[Category: Capsid]]
	[[Category: Capsid protein]]		[[Category: Capsid protein]]
Line 40:		Line 27:
	[[Category: Structural protein]]		[[Category: Structural protein]]
	[[Category: Virus]]		[[Category: Virus]]
		+	[[Category: Virus-rna complex]]
		+	[[Category: Virus/rna]]
	[[Category: Virus/viral protein/rna]]		[[Category: Virus/viral protein/rna]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 07:55:10 2009''