2j3i - Revision history

OCA at 08:00, 19 January 2022

OCA — Wed, 19 Jan 2022 08:00:39 GMT

←Older revision		Revision as of 08:00, 19 January 2022
Line 3:		Line 3:
	<StructureSection load='2j3i' size='340' side='right'caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2j3i' size='340' side='right'caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2J3I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J3I FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [~~http~~://pdbe.org/2j3i PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2j3i PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2j3i ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [https://pdbe.org/2j3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [https://www.ebi.ac.uk/pdbsum/2j3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j3i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/P1_ARATH P1_ARATH]] Catalyzes the reduction of the 7-8 double bond of phenylpropanal substrates, such as p-coumaryl aldehyde and coniferyl aldehyde (in vitro). Has activity towards toxic substrates, such as 4-hydroxy-(2E)-nonenal (in vitro). May play a distinct role in plant antioxidant defense and is possibly involved in NAD(P)/NAD(P)H homeostasis.	+	[[https://www.uniprot.org/uniprot/P1_ARATH P1_ARATH]] Catalyzes the reduction of the 7-8 double bond of phenylpropanal substrates, such as p-coumaryl aldehyde and coniferyl aldehyde (in vitro). Has activity towards toxic substrates, such as 4-hydroxy-(2E)-nonenal (in vitro). May play a distinct role in plant antioxidant defense and is possibly involved in NAD(P)/NAD(P)H homeostasis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:38, 15 April 2020

OCA — Wed, 15 Apr 2020 07:38:49 GMT

←Older revision		Revision as of 07:38, 15 April 2020
Line 1:		Line 1:

	==Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Binary Complex==		==Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Binary Complex==
-	<StructureSection load='2j3i' size='340' side='right' caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='2j3i' size='340' side='right'caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2J3I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2J3I FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://pdbe.org/2j3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j3i ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://pdbe.org/2j3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j3i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Arath]]		[[Category: Arath]]
		+	[[Category: Large Structures]]
	[[Category: Bedgar, D L]]		[[Category: Bedgar, D L]]
	[[Category: Davin, L B]]		[[Category: Davin, L B]]

OCA at 06:53, 11 July 2018

OCA — Wed, 11 Jul 2018 06:53:40 GMT

←Older revision		Revision as of 06:53, 11 July 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE~~ (AT5G16970)-~~BINARY COMPLEX~~==	+
		+	==Crystal structure of Arabidopsis thaliana Double Bond Reductase (AT5G16970)-Binary Complex==
	<StructureSection load='2j3i' size='340' side='right' caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2j3i' size='340' side='right' caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://pdbe.org/2j3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://pdbe.org/2j3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j3i ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/2j3i_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/2j3i_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 09:36, 8 February 2016

OCA — Mon, 08 Feb 2016 09:36:37 GMT

←Older revision		Revision as of 09:36, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j3i ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:17, 10 September 2015

OCA — Thu, 10 Sep 2015 10:17:12 GMT

←Older revision		Revision as of 10:17, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2j3i' size='340' side='right' caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2j3i' size='340' side='right' caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arabidopsis_thaliana Arabidopsis thaliana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J3I FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J3I FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://pdbe.org/2j3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2j3i" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arabidopsis thaliana~~]]	+	[[Category: Arath]]
	[[Category: Bedgar, D L]]		[[Category: Bedgar, D L]]
	[[Category: Davin, L B]]		[[Category: Davin, L B]]
Line 42:		Line 43:
	[[Category: Youn, B]]		[[Category: Youn, B]]
	[[Category: Apo form]]		[[Category: Apo form]]
		+	[[Category: Arabidopsis thaliana]]
	[[Category: Binary complex nadp]]		[[Category: Binary complex nadp]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 22:22, 24 December 2014

OCA — Wed, 24 Dec 2014 22:22:10 GMT

←Older revision		Revision as of 22:22, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J3I FirstGlance]. <br>		<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J3I FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/P1_ARATH P1_ARATH]] Catalyzes the reduction of the 7-8 double bond of phenylpropanal substrates, such as p-coumaryl aldehyde and coniferyl aldehyde (in vitro). Has activity towards toxic substrates, such as 4-hydroxy-(2E)-nonenal (in vitro). May play a distinct role in plant antioxidant defense and is possibly involved in NAD(P)/NAD(P)H homeostasis.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
-	[[Category: Bedgar, D L.]]	+	[[Category: Bedgar, D L]]
-	[[Category: Davin, L B.]]	+	[[Category: Davin, L B]]
-	[[Category: Harper, A R.]]	+	[[Category: Harper, A R]]
-	[[Category: Kang, C.]]	+	[[Category: Kang, C]]
-	[[Category: Kim, S J.]]	+	[[Category: Kim, S J]]
-	[[Category: Lee, C.]]	+	[[Category: Lee, C]]
-	[[Category: Lewis, N G.]]	+	[[Category: Lewis, N G]]
-	[[Category: Moinuddin, S G.]]	+	[[Category: Moinuddin, S G]]
-	[[Category: Youn, B.]]	+	[[Category: Youn, B]]
	[[Category: Apo form]]		[[Category: Apo form]]
-	[[Category: Arabidopsis thaliana]]
	[[Category: Binary complex nadp]]		[[Category: Binary complex nadp]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 08:02, 30 September 2014

OCA — Tue, 30 Sep 2014 08:02:00 GMT

←Older revision		Revision as of 08:02, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2j3i.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE (AT5G16970)-BINARY COMPLEX==
		+	<StructureSection load='2j3i' size='340' side='right' caption='[[2j3i]], [[Resolution\|resolution]] 2.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J3I FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2j3h\|2j3h]], [[2j3j\|2j3j]], [[2j3k\|2j3k]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j3i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j3i RCSB], [http://www.ebi.ac.uk/pdbsum/2j3i PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/2j3i_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In this study, we determined the crystal structures of the apoform, binary, and ternary complexes of the Arabidopsis alkenal double bond reductase encoded by At5g16970. This protein, one of 11 homologues in Arabidopsis thaliana, is most closely related to the Pinus taeda phenylpropenal double bond reductase, involved in, for example, heartwood formation. Both enzymes also have essential roles in plant defense, and can function by catalyzing the reduction of the 7-8-double bond of phenylpropanal substrates, such as p-coumaryl and coniferyl aldehydes in vitro. At5g16970 is also capable of reducing toxic substrates with the same alkenal functionality, such as 4-hydroxy-(2E)-nonenal. The overall fold of At5g16970 is similar to that of the zinc-independent medium chain dehydrogenase/reductase superfamily, the members of which have two domains and are dimeric in nature, i.e. in contrast to their original classification as being zinc-containing oxidoreductases. As provisionally anticipated from the kinetic data, the shape of the binding pocket can readily accommodate p-coumaryl aldehyde, coniferyl aldehyde, 4-hydroxy-(2E)-nonenal, and 2-alkenals. However, the enzyme kinetic data among these potential substrates differ, favoring p-coumaryl aldehyde. Tyr-260 is provisionally proposed to function as a general acid/base for hydride transfer. A catalytic mechanism for this reduction, and its applicability to related important detoxification mammalian proteins, is also proposed.

-	~~{{STRUCTURE_2j3i\| PDB=2j3i \| SCENE= }}~~	+	Mechanistic and structural studies of apoform, binary, and ternary complexes of the Arabidopsis alkenal double bond reductase At5g16970.,Youn B, Kim SJ, Moinuddin SG, Lee C, Bedgar DL, Harper AR, Davin LB, Lewis NG, Kang C J Biol Chem. 2006 Dec 29;281(52):40076-88. Epub 2006 Oct 6. PMID:17028190<ref>PMID:17028190</ref>

-	~~===CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE (AT5G16970)-BINARY COMPLEX===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17028190}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2j3i]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017028190<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Bedgar, D L.]]		[[Category: Bedgar, D L.]]

OCA: Protected "2j3i" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 18:06:36 GMT

Protected "2j3i" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:06, 7 January 2013

OCA at 18:06, 7 January 2013

OCA — Mon, 07 Jan 2013 18:06:33 GMT

←Older revision		Revision as of 18:06, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2j3i.png\|left\|200px]]		[[Image:2j3i.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2j3i", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2j3i\| PDB=2j3i \| SCENE= }}		{{STRUCTURE_2j3i\| PDB=2j3i \| SCENE= }}

	===CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE (AT5G16970)-BINARY COMPLEX===		===CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA DOUBLE BOND REDUCTASE (AT5G16970)-BINARY COMPLEX===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17028190}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17028190 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17028190}}		{{ABSTRACT_PUBMED_17028190}}

	==About this Structure==		==About this Structure==
-	~~2J3I~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA].	+	[[2j3i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17028190~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017028190</ref><references group="xtra"/>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Bedgar, D L.]]		[[Category: Bedgar, D L.]]
Line 38:		Line 26:
	[[Category: Binary complex nadp]]		[[Category: Binary complex nadp]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:01:52 2009''

OCA at 19:01, 16 February 2009

OCA — Mon, 16 Feb 2009 19:01:53 GMT

←Older revision		Revision as of 19:01, 16 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2J3I is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA].	+	2J3I is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J3I OCA].

	==Reference==		==Reference==
-	Mechanistic and structural studies of apoform, binary, and ternary complexes of the Arabidopsis alkenal double bond reductase At5g16970., Youn B, Kim SJ, Moinuddin SG, Lee C, Bedgar DL, Harper AR, Davin LB, Lewis NG, Kang C, J Biol Chem. 2006 Dec 29;281(52):40076-88. Epub 2006 Oct 6. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17028190 17028190]~~	+	<ref group="xtra">PMID:17028190</ref><references group="xtra"/>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
-	[[Category: Single protein]]
	[[Category: Bedgar, D L.]]		[[Category: Bedgar, D L.]]
	[[Category: Davin, L B.]]		[[Category: Davin, L B.]]
Line 40:		Line 39:
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon ~~Jul 28 01~~:37:~~51 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:01:52 2009''