2j5p - Revision history

OCA at 05:35, 15 May 2024

OCA — Wed, 15 May 2024 05:35:34 GMT

←Older revision		Revision as of 05:35, 15 May 2024
Line 1:		Line 1:

	==E. coli FtsK gamma domain==		==E. coli FtsK gamma domain==
-	<StructureSection load='2j5p' size='340' side='right'caption='[[2j5p~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2j5p' size='340' side='right'caption='[[2j5p]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2J5P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J5P FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[2ius\|2ius]], [[2j5o\|2j5o]]~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [~~http~~://pdbe.org/2j5p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2j5p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [https://pdbe.org/2j5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [https://www.ebi.ac.uk/pdbsum/2j5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5p ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/FTSK_ECOLI FTSK_ECOLI] Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif. Stoppage of translocation is accompanied by a reduction in ATPase activity. Also stimulates topoisomerase 4 activity. Required for the targeting of FtsQ, FtsL and FtsI to the septum.<ref>PMID:9829960</ref> <ref>PMID:9723913</ref> <ref>PMID:11703663</ref> <ref>PMID:11832210</ref> <ref>PMID:15522074</ref> <ref>PMID:16553881</ref> <ref>PMID:18363794</ref> <ref>PMID:19246541</ref> <ref>PMID:19854947</ref> <ref>PMID:20081205</ref> <ref>PMID:21371996</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Allen~~, M D~~]]	+	[[Category: Allen MD]]
-	[[Category: Arciszewska, L]]	+	[[Category: Arciszewska L]]
-	[[Category: Baker, R]]	+	[[Category: Baker R]]
-	~~[[Category: Bekker, C de~~]]	+	[[Category: Bycroft M]]
-	[[Category: Bycroft, M]]	+	[[Category: Freund SM]]
-	[[Category: Freund~~, S M~~]]	+	[[Category: Lowe J]]
-	[[Category: Lowe, J]]	+	[[Category: Sherratt DJ]]
-	[[Category: Sherratt~~, D J~~]]	+	[[Category: Sivanathan V]]
-	[[Category: Sivanathan, V]]	+	[[Category: De Bekker C]]
-	[[Category: ~~Bacterial cell division]]~~	+
-	~~[[Category: Dna segregation]]~~	+
-	~~[[Category: Ftsk]]~~	+
-	~~[[Category: Kop]]~~	+
-	~~[[Category: Recombination]]~~	+
-	~~[[Category: Xercd~~]]	+

OCA at 07:55, 4 November 2020

OCA — Wed, 04 Nov 2020 07:55:20 GMT

←Older revision		Revision as of 07:55, 4 November 2020
Line 1:		Line 1:

	==E. coli FtsK gamma domain==		==E. coli FtsK gamma domain==
-	<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2j5p' size='340' side='right'caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2J5P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2J5P FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://pdbe.org/2j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://pdbe.org/2j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5p ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Allen, M D]]		[[Category: Allen, M D]]
	[[Category: Arciszewska, L]]		[[Category: Arciszewska, L]]

OCA at 09:50, 30 January 2019

OCA — Wed, 30 Jan 2019 09:50:23 GMT

←Older revision		Revision as of 09:50, 30 January 2019
Line 3:		Line 3:
	<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://pdbe.org/2j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://pdbe.org/2j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5p ProSAT]</span></td></tr>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5p_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5p_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: Allen, M D]]		[[Category: Allen, M D]]
	[[Category: Arciszewska, L]]		[[Category: Arciszewska, L]]

OCA at 06:16, 19 April 2017

OCA — Wed, 19 Apr 2017 06:16:20 GMT

←Older revision		Revision as of 06:16, 19 April 2017
Line 1:		Line 1:
-	==E. ~~COLI FTSK GAMMA DOMAIN~~==	+
		+	==E. coli FtsK gamma domain==
	<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://pdbe.org/2j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://pdbe.org/2j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2j5p ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j5p ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 29:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus coli migula 1895]]
	[[Category: Allen, M D]]		[[Category: Allen, M D]]
	[[Category: Arciszewska, L]]		[[Category: Arciszewska, L]]
	[[Category: Baker, R]]		[[Category: Baker, R]]
-	[[Category: Bekker, C De]]	+	[[Category: Bekker, C de]]
	[[Category: Bycroft, M]]		[[Category: Bycroft, M]]
	[[Category: Freund, S M]]		[[Category: Freund, S M]]

OCA at 01:22, 12 September 2015

OCA — Sat, 12 Sep 2015 01:22:38 GMT

←Older revision		Revision as of 01:22, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://pdbe.org/2j5p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2j5p" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Allen, M D]]		[[Category: Allen, M D]]
	[[Category: Arciszewska, L]]		[[Category: Arciszewska, L]]

OCA at 16:22, 19 January 2015

OCA — Mon, 19 Jan 2015 16:22:29 GMT

←Older revision		Revision as of 16:22, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>		<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Allen, M D.]]	+	[[Category: Allen, M D]]
-	[[Category: Arciszewska, L.]]	+	[[Category: Arciszewska, L]]
-	[[Category: Baker, R.]]	+	[[Category: Baker, R]]
-	[[Category: Bekker, C De.]]	+	[[Category: Bekker, C De]]
-	[[Category: Bycroft, M.]]	+	[[Category: Bycroft, M]]
-	[[Category: Freund, S M.]]	+	[[Category: Freund, S M]]
-	[[Category: Lowe, J.]]	+	[[Category: Lowe, J]]
-	[[Category: Sherratt, D J.]]	+	[[Category: Sherratt, D J]]
-	[[Category: Sivanathan, V.]]	+	[[Category: Sivanathan, V]]
	[[Category: Bacterial cell division]]		[[Category: Bacterial cell division]]
	[[Category: Dna segregation]]		[[Category: Dna segregation]]

OCA at 09:19, 30 September 2014

OCA — Tue, 30 Sep 2014 09:19:31 GMT

←Older revision		Revision as of 09:19, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2j5p.~~png~~\|~~left~~\|200px]]	+	==E. COLI FTSK GAMMA DOMAIN==
		+	<StructureSection load='2j5p' size='340' side='right' caption='[[2j5p]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J5P FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ius\|2ius]], [[2j5o\|2j5o]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j5p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2j5p RCSB], [http://www.ebi.ac.uk/pdbsum/2j5p PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/2j5p_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The bacterial septum-located DNA translocase FtsK coordinates circular chromosome segregation with cell division. Rapid translocation of DNA by FtsK is directed by 8-base-pair DNA motifs (KOPS), so that newly replicated termini are brought together at the developing septum, thereby facilitating completion of chromosome segregation. Translocase functions reside in three domains, alpha, beta and gamma. FtsKalphabeta are necessary and sufficient for ATP hydrolysis-dependent DNA translocation, which is modulated by FtsKgamma through its interaction with KOPS. By solving the FtsKgamma structure by NMR, we show that gamma is a winged-helix domain. NMR chemical shift mapping localizes the DNA-binding site on the gamma domain. Mutated proteins with substitutions in the FtsKgamma DNA-recognition helix are impaired in DNA binding and KOPS recognition, yet remain competent in DNA translocation and XerCD-dif site-specific recombination, which facilitates the late stages of chromosome segregation.

-	~~{{STRUCTURE_2j5p\| PDB=2j5p \| SCENE= }}~~	+	The FtsK gamma domain directs oriented DNA translocation by interacting with KOPS.,Sivanathan V, Allen MD, de Bekker C, Baker R, Arciszewska LK, Freund SM, Bycroft M, Lowe J, Sherratt DJ Nat Struct Mol Biol. 2006 Nov;13(11):965-72. Epub 2006 Oct 22. PMID:17057717<ref>PMID:17057717</ref>

-	~~===E. COLI FTSK GAMMA DOMAIN===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17057717}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2j5p]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017057717<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Allen, M D.]]		[[Category: Allen, M D.]]

OCA: Protected "2j5p" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 14:13:13 GMT

Protected "2j5p" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:13, 7 January 2013

OCA at 14:13, 7 January 2013

OCA — Mon, 07 Jan 2013 14:13:10 GMT

←Older revision		Revision as of 14:13, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2j5p.png\|left\|200px]]		[[Image:2j5p.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2j5p", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2j5p\| PDB=2j5p \| SCENE= }}		{{STRUCTURE_2j5p\| PDB=2j5p \| SCENE= }}

	===E. COLI FTSK GAMMA DOMAIN===		===E. COLI FTSK GAMMA DOMAIN===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17057717}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17057717 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17057717}}		{{ABSTRACT_PUBMED_17057717}}

	==About this Structure==		==About this Structure==
-	~~2J5P~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA].	+	[[2j5p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17057717~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017057717</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Allen, M D.]]		[[Category: Allen, M D.]]
Line 40:		Line 28:
	[[Category: Recombination]]		[[Category: Recombination]]
	[[Category: Xercd]]		[[Category: Xercd]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:06:17 2009''

OCA at 07:06, 18 February 2009

OCA — Wed, 18 Feb 2009 07:06:20 GMT

←Older revision		Revision as of 07:06, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	2J5P is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA].	+	2J5P is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J5P OCA].

	==Reference==		==Reference==
-	The FtsK gamma domain directs oriented DNA translocation by interacting with KOPS., Sivanathan V, Allen MD, de Bekker C, Baker R, Arciszewska LK, Freund SM, Bycroft M, Lowe J, Sherratt DJ, Nat Struct Mol Biol. 2006 Nov;13(11):965-72. Epub 2006 Oct 22. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17057717 17057717]~~	+	<ref group="xtra">PMID:17057717</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Allen, M D.]]		[[Category: Allen, M D.]]
	[[Category: Arciszewska, L.]]		[[Category: Arciszewska, L.]]
Line 42:		Line 41:
	[[Category: Xercd]]		[[Category: Xercd]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 15~~:19:~~45 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:06:17 2009''