2jcg - Revision history

OCA at 14:42, 13 December 2023

OCA — Wed, 13 Dec 2023 14:42:53 GMT

←Older revision		Revision as of 14:42, 13 December 2023
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	<StructureSection load='2jcg' size='340' side='right'caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2jcg' size='340' side='right'caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_14581 Atcc 14581~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JCG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium Priestia megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JCG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [https://pdbe.org/2jcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [https://www.ebi.ac.uk/pdbsum/2jcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [https://pdbe.org/2jcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [https://www.ebi.ac.uk/pdbsum/2jcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~CCPA_BACME CCPA_BACME]~~] Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/CCPA_PRIMG CCPA_PRIMG] Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 14581]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Hinrichs, W~~]]	+	[[Category: Priestia megaterium]]
-	[[Category: ~~Palm, G J~~]]	+	[[Category: Hinrichs W]]
-	[[Category: ~~Panjikar, S~~]]	+	[[Category: Palm GJ]]
-	[[Category: ~~Singh, R K~~]]	+	[[Category: Panjikar S]]
-	[[Category: ~~Activator]]~~	+	[[Category: Singh RK]]
-	~~[[Category: Apo- form]]~~	+
-	~~[[Category: Bacillus]]~~	+
-	~~[[Category: Catabolite control protein some]]~~	+
-	~~[[Category: Ccpa]]~~	+
-	~~[[Category: Dna-binding]]~~	+
-	~~[[Category: Megaterium]]~~	+
-	~~[[Category: Repressor]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transcription regulation~~]]	+

OCA at 10:07, 12 May 2021

OCA — Wed, 12 May 2021 10:07:17 GMT

←Older revision		Revision as of 10:07, 12 May 2021
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	<StructureSection load='2jcg' size='340' side='right'caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2jcg' size='340' side='right'caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2JCG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JCG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [~~http~~://pdbe.org/2jcg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2jcg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [https://pdbe.org/2jcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [https://www.ebi.ac.uk/pdbsum/2jcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CCPA_BACME CCPA_BACME]] Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions (By similarity).	+	[[https://www.uniprot.org/uniprot/CCPA_BACME CCPA_BACME]] Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:23, 24 July 2019

OCA — Wed, 24 Jul 2019 07:23:34 GMT

←Older revision		Revision as of 07:23, 24 July 2019
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	==Apo form of the catabolite control protein A (ccpA) from bacillus megaterium, with the DNA binding domain==		==Apo form of the catabolite control protein A (ccpA) from bacillus megaterium, with the DNA binding domain==
-	<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='2jcg' size='340' side='right'caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JCG FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JCG FirstGlance]. <br>
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	==See Also==		==See Also==
-	*[[Catabolite control protein\|Catabolite control protein]]	+	*[[Catabolite control protein 3D structures\|Catabolite control protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 14581]]		[[Category: Atcc 14581]]
		+	[[Category: Large Structures]]
	[[Category: Hinrichs, W]]		[[Category: Hinrichs, W]]
	[[Category: Palm, G J]]		[[Category: Palm, G J]]

OCA at 06:56, 11 July 2018

OCA — Wed, 11 Jul 2018 06:56:14 GMT

←Older revision		Revision as of 06:56, 11 July 2018
Line 1:		Line 1:
-	==~~APO FORM OF THE CATABOLITE CONTROL PROTEIN~~ A (~~CCPA~~) ~~FROM BACILLUS MEGATERIUM~~, ~~WITH THE~~ DNA ~~BINDING DOMAIN~~==	+
		+	==Apo form of the catabolite control protein A (ccpA) from bacillus megaterium, with the DNA binding domain==
	<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://pdbe.org/2jcg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://pdbe.org/2jcg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/2jcg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/2jcg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jcg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:35, 11 September 2015

OCA — Fri, 11 Sep 2015 08:35:13 GMT

←Older revision		Revision as of 08:35, 11 September 2015
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	<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_megaterium Bacillus megaterium~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JCG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JCG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://pdbe.org/2jcg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2jcg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus megaterium~~]]	+	[[Category: Atcc 14581]]
	[[Category: Hinrichs, W]]		[[Category: Hinrichs, W]]
	[[Category: Palm, G J]]		[[Category: Palm, G J]]

OCA at 13:56, 25 December 2014

OCA — Thu, 25 Dec 2014 13:56:48 GMT

←Older revision		Revision as of 13:56, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JCG FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JCG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CCPA_BACME CCPA_BACME]] Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus megaterium]]		[[Category: Bacillus megaterium]]
-	[[Category: Hinrichs, W.]]	+	[[Category: Hinrichs, W]]
-	[[Category: Palm, G J.]]	+	[[Category: Palm, G J]]
-	[[Category: Panjikar, S.]]	+	[[Category: Panjikar, S]]
-	[[Category: Singh, R K.]]	+	[[Category: Singh, R K]]
	[[Category: Activator]]		[[Category: Activator]]
	[[Category: Apo- form]]		[[Category: Apo- form]]

OCA at 10:50, 3 October 2014

OCA — Fri, 03 Oct 2014 10:50:24 GMT

←Older revision		Revision as of 10:50, 3 October 2014
Line 2:		Line 2:
	<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. <br>	+	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JCG FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>		<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>
	<table>		<table>
Line 24:		Line 23:
	Structure of the apo form of the catabolite control protein A (CcpA) from Bacillus megaterium with a DNA-binding domain.,Singh RK, Palm GJ, Panjikar S, Hinrichs W Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt, 4):253-7. Epub 2007 Mar 12. PMID:17401189<ref>PMID:17401189</ref>		Structure of the apo form of the catabolite control protein A (CcpA) from Bacillus megaterium with a DNA-binding domain.,Singh RK, Palm GJ, Panjikar S, Hinrichs W Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt, 4):253-7. Epub 2007 Mar 12. PMID:17401189<ref>PMID:17401189</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Catabolite control protein\|Catabolite control protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:38, 1 May 2014

OCA — Thu, 01 May 2014 09:38:05 GMT

←Older revision		Revision as of 09:38, 1 May 2014
Line 2:		Line 2:
	<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. <br>	+	<table><tr><td colspan='2'>[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. <br>
-	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
-	<b>[[Related_structure\|Related:]]</b> [[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]<br>	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]</td></tr>
-	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span><br>	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span></td></tr>
		+	<table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
-	[[Image:Consurf_key_small.gif\|right]]	+	[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
Line 17:		Line 18:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
	Crystal structure determination of catabolite control protein A (CcpA) at 2.6 A resolution reveals for the first time the structure of a full-length apo-form LacI-GalR family repressor protein. In the crystal structures of these transcription regulators, the three-helix bundle of the DNA-binding domain has only been observed in cognate DNA complexes; it has not been observed in other crystal structures owing to its mobility. In the crystal packing of apo-CcpA, the protein-protein contacts between the N-terminal three-helix bundle and the core domain consisted of interactions between the homodimers that were similar to those between the corepressor protein HPr and the CcpA N-subdomain in the ternary DNA complex. In contrast to the DNA complex, the apo-CcpA structure reveals large subdomain movements in the core, resulting in a complete loss of contacts between the N-subdomains of the homodimer.		Crystal structure determination of catabolite control protein A (CcpA) at 2.6 A resolution reveals for the first time the structure of a full-length apo-form LacI-GalR family repressor protein. In the crystal structures of these transcription regulators, the three-helix bundle of the DNA-binding domain has only been observed in cognate DNA complexes; it has not been observed in other crystal structures owing to its mobility. In the crystal packing of apo-CcpA, the protein-protein contacts between the N-terminal three-helix bundle and the core domain consisted of interactions between the homodimers that were similar to those between the corepressor protein HPr and the CcpA N-subdomain in the ternary DNA complex. In contrast to the DNA complex, the apo-CcpA structure reveals large subdomain movements in the core, resulting in a complete loss of contacts between the N-subdomains of the homodimer.
Line 23:		Line 25:

	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>		From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:58, 30 April 2014

OCA — Wed, 30 Apr 2014 09:58:05 GMT

←Older revision		Revision as of 09:58, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. <br>		[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. <br>
-	<b>Related:</b> [[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]<br>	+	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<b>[[Related_structure\|Related:]]</b> [[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]<br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jcg RCSB], [http://www.ebi.ac.uk/pdbsum/2jcg PDBsum]</span><br>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|right]]		[[Image:Consurf_key_small.gif\|right]]

OCA at 08:22, 30 April 2014

OCA — Wed, 30 Apr 2014 08:22:14 GMT

←Older revision		Revision as of 08:22, 30 April 2014
Line 1:		Line 1:
-	[[Image:~~2jcg~~.~~png~~\|~~left~~\|~~200px~~]]	+	==APO FORM OF THE CATABOLITE CONTROL PROTEIN A (CCPA) FROM BACILLUS MEGATERIUM, WITH THE DNA BINDING DOMAIN==
		+	<StructureSection load='2jcg' size='340' side='right' caption='[[2jcg]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	[[2jcg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA]. <br>
		+	<b>Related:</b> [[1rzr\|1rzr]], [[1sxg\|1sxg]], [[1sxh\|1sxh]], [[1sxi\|1sxi]], [[1zvv\|1zvv]]<br>
		+	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/2jcg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	== Publication Abstract from PubMed ==
		+	Crystal structure determination of catabolite control protein A (CcpA) at 2.6 A resolution reveals for the first time the structure of a full-length apo-form LacI-GalR family repressor protein. In the crystal structures of these transcription regulators, the three-helix bundle of the DNA-binding domain has only been observed in cognate DNA complexes; it has not been observed in other crystal structures owing to its mobility. In the crystal packing of apo-CcpA, the protein-protein contacts between the N-terminal three-helix bundle and the core domain consisted of interactions between the homodimers that were similar to those between the corepressor protein HPr and the CcpA N-subdomain in the ternary DNA complex. In contrast to the DNA complex, the apo-CcpA structure reveals large subdomain movements in the core, resulting in a complete loss of contacts between the N-subdomains of the homodimer.

-	~~<!--~~	+	Structure of the apo form of the catabolite control protein A (CcpA) from Bacillus megaterium with a DNA-binding domain.,Singh RK, Palm GJ, Panjikar S, Hinrichs W Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Apr 1;63(Pt, 4):253-7. Epub 2007 Mar 12. PMID:17401189<ref>PMID:17401189</ref>
-	~~The line below this paragraph, containing "STRUCTURE_2jcg", creates the "~~Structure ~~Box" on~~ the ~~page.~~	+
-	~~You may change~~ the ~~PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter~~ (~~which sets the initial scene displayed when the page is loaded~~),	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2jcg\| PDB=2jcg \| SCENE= }}~~	+

-	~~===APO FORM OF THE CATABOLITE CONTROL PROTEIN A (CCPA) FROM BACILLUS MEGATERIUM~~, ~~WITH THE DNA BINDING DOMAIN===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	== References ==
-		+	<references/>
-	~~<!--~~	+	__TOC__
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_17401189}}, adds~~ the ~~Publication Abstract to the page~~	+	</StructureSection>
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 17401189 is the PubMed ID number~~.	+
-	-->	+
-	~~{{ABSTRACT_PUBMED_17401189}}~~	+
-		+
-	==~~About this Structure~~==	+
-	~~[[2jcg]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCG OCA].~~	+
-		+
-	~~==Reference==~~	+
-	<~~ref group="xtra">PMID:017401189</ref><ref group="xtra">PMID:010666630</ref><references group="xtra"~~/>	+
	[[Category: Bacillus megaterium]]		[[Category: Bacillus megaterium]]
	[[Category: Hinrichs, W.]]		[[Category: Hinrichs, W.]]