2je3 - Revision history

OCA at 06:41, 1 May 2024

OCA — Wed, 01 May 2024 06:41:58 GMT

←Older revision		Revision as of 06:41, 1 May 2024
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	<StructureSection load='2je3' size='340' side='right'caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2je3' size='340' side='right'caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_nitrosomonas"_lehmann_and_neumann_1899 "bacterium nitrosomonas" lehmann and neumann 1899~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEC:HEME+C'>HEC</scene>~~, ~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[2je2\|2je2]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [https://pdbe.org/2je3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [https://www.ebi.ac.uk/pdbsum/2je3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2je3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [https://pdbe.org/2je3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [https://www.ebi.ac.uk/pdbsum/2je3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2je3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q50927_NITER Q50927_NITER]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2je3 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2je3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We have determined the 1.8 A X-ray crystal structure of a monoheme c-type cytochrome, cytochrome P460, from Nitrosomonas europea. The chromophore possesses unusual spectral properties analogous to those of the catalytic heme P460 of hydroxylamine oxidoreductase (HAO), the only known heme in biology to withdraw electrons from an iron-coordinated substrate. The analysis reveals a homodimeric structure and elucidates a new c-type cytochrome fold that is predominantly beta-sheet. In addition to the two cysteine thioether links to the porphyrin typical of c-type hemes, there is a third proteinaceous link involving a conserved lysine. The covalent bond is between the lysine side-chain nitrogen and the 13'-meso carbon of the heme, which, following cross-link formation, is sp3-hybridized, demonstrating the loss of conjugation at this position within the porphyrin. The structure has implications for the analogous tyrosine-heme meso carbon cross-link observed in HAO.
-
-	The crystal structure of cytochrome P460 of Nitrosomonas europaea reveals a novel cytochrome fold and heme-protein cross-link.,Pearson AR, Elmore BO, Yang C, Ferrara JD, Hooper AB, Wilmot CM Biochemistry. 2007 Jul 17;46(28):8340-9. Epub 2007 Jun 21. PMID:17583915<ref>PMID:17583915</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 2je3" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacterium nitrosomonas lehmann and neumann 1899]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Elmore~~, B O~~]]	+	[[Category: Nitrosomonas europaea]]
-	[[Category: Ferrara~~, J D~~]]	+	[[Category: Elmore BO]]
-	[[Category: Hooper~~, A B~~]]	+	[[Category: Ferrara JD]]
-	[[Category: Pearson~~, A R~~]]	+	[[Category: Hooper AB]]
-	[[Category: Wilmot~~, C M~~]]	+	[[Category: Pearson AR]]
-	[[Category: Yang, C]]	+	[[Category: Wilmot CM]]
-	~~[[Category: Cross-linked heme]]~~	+	[[Category: Yang C]]
-	~~[[Category: Cytochrome p460]]~~	+
-	~~[[Category: Heme p460]]~~	+
-	~~[[Category: Metal binding protein~~]]	+

OCA at 08:08, 19 January 2022

OCA — Wed, 19 Jan 2022 08:08:38 GMT

←Older revision		Revision as of 08:08, 19 January 2022
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	<StructureSection load='2je3' size='340' side='right'caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2je3' size='340' side='right'caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_nitrosomonas"_lehmann_and_neumann_1899 "bacterium nitrosomonas" lehmann and neumann 1899]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_nitrosomonas"_lehmann_and_neumann_1899 "bacterium nitrosomonas" lehmann and neumann 1899]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2je2\|2je2]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [~~http~~://pdbe.org/2je3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2je3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2je3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [https://pdbe.org/2je3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [https://www.ebi.ac.uk/pdbsum/2je3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2je3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:48, 15 April 2020

OCA — Wed, 15 Apr 2020 07:48:53 GMT

←Older revision		Revision as of 07:48, 15 April 2020
Line 1:		Line 1:

	==Cytochrome P460 from Nitrosomonas europaea - probable physiological form==		==Cytochrome P460 from Nitrosomonas europaea - probable physiological form==
-	<StructureSection load='2je3' size='340' side='right' caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='2je3' size='340' side='right'caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_nitrosomonas"_lehmann_and_neumann_1899 "bacterium nitrosomonas" lehmann and neumann 1899]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_nitrosomonas"_lehmann_and_neumann_1899 "bacterium nitrosomonas" lehmann and neumann 1899]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://pdbe.org/2je3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2je3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://pdbe.org/2je3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2je3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Bacterium nitrosomonas lehmann and neumann 1899]]		[[Category: Bacterium nitrosomonas lehmann and neumann 1899]]
		+	[[Category: Large Structures]]
	[[Category: Elmore, B O]]		[[Category: Elmore, B O]]
	[[Category: Ferrara, J D]]		[[Category: Ferrara, J D]]

OCA at 06:39, 11 July 2018

OCA — Wed, 11 Jul 2018 06:39:14 GMT

←Older revision		Revision as of 06:39, 11 July 2018
Line 1:		Line 1:
-	==~~CYTOCHROME~~ P460 ~~FROM NITROSOMONAS EUROPAEA~~ - ~~PROBABLE PHYSIOLOGICAL FORM~~==	+
		+	==Cytochrome P460 from Nitrosomonas europaea - probable physiological form==
	<StructureSection load='2je3' size='340' side='right' caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2je3' size='340' side='right' caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://pdbe.org/2je3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://pdbe.org/2je3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2je3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2je3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2je3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 19:44, 8 February 2016

OCA — Mon, 08 Feb 2016 19:44:36 GMT

←Older revision		Revision as of 19:44, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2je3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:47, 10 September 2015

OCA — Thu, 10 Sep 2015 14:47:45 GMT

←Older revision		Revision as of 14:47, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2je3' size='340' side='right' caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2je3' size='340' side='right' caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Nitrosomonas_europaea Nitrosomonas europaea~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_nitrosomonas"_lehmann_and_neumann_1899 "bacterium nitrosomonas" lehmann and neumann 1899]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://pdbe.org/2je3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2je3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Nitrosomonas europaea~~]]	+	[[Category: Bacterium nitrosomonas lehmann and neumann 1899]]
	[[Category: Elmore, B O]]		[[Category: Elmore, B O]]
	[[Category: Ferrara, J D]]		[[Category: Ferrara, J D]]

OCA at 16:28, 19 January 2015

OCA — Mon, 19 Jan 2015 16:28:27 GMT

←Older revision		Revision as of 16:28, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Nitrosomonas europaea]]		[[Category: Nitrosomonas europaea]]
-	[[Category: Elmore, B O.]]	+	[[Category: Elmore, B O]]
-	[[Category: Ferrara, J D.]]	+	[[Category: Ferrara, J D]]
-	[[Category: Hooper, A B.]]	+	[[Category: Hooper, A B]]
-	[[Category: Pearson, A R.]]	+	[[Category: Pearson, A R]]
-	[[Category: Wilmot, C M.]]	+	[[Category: Wilmot, C M]]
-	[[Category: Yang, C.]]	+	[[Category: Yang, C]]
	[[Category: Cross-linked heme]]		[[Category: Cross-linked heme]]
	[[Category: Cytochrome p460]]		[[Category: Cytochrome p460]]
	[[Category: Heme p460]]		[[Category: Heme p460]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 09:20, 30 September 2014

OCA — Tue, 30 Sep 2014 09:20:12 GMT

←Older revision		Revision as of 09:20, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2je3.~~png~~\|~~left~~\|200px]]	+	==CYTOCHROME P460 FROM NITROSOMONAS EUROPAEA - PROBABLE PHYSIOLOGICAL FORM==
		+	<StructureSection load='2je3' size='340' side='right' caption='[[2je3]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JE3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2je2\|2je2]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2je3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2je3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2je3 RCSB], [http://www.ebi.ac.uk/pdbsum/2je3 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/je/2je3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the 1.8 A X-ray crystal structure of a monoheme c-type cytochrome, cytochrome P460, from Nitrosomonas europea. The chromophore possesses unusual spectral properties analogous to those of the catalytic heme P460 of hydroxylamine oxidoreductase (HAO), the only known heme in biology to withdraw electrons from an iron-coordinated substrate. The analysis reveals a homodimeric structure and elucidates a new c-type cytochrome fold that is predominantly beta-sheet. In addition to the two cysteine thioether links to the porphyrin typical of c-type hemes, there is a third proteinaceous link involving a conserved lysine. The covalent bond is between the lysine side-chain nitrogen and the 13'-meso carbon of the heme, which, following cross-link formation, is sp3-hybridized, demonstrating the loss of conjugation at this position within the porphyrin. The structure has implications for the analogous tyrosine-heme meso carbon cross-link observed in HAO.

-	~~{{STRUCTURE_2je3\| PDB=2je3 \| SCENE= }}~~	+	The crystal structure of cytochrome P460 of Nitrosomonas europaea reveals a novel cytochrome fold and heme-protein cross-link.,Pearson AR, Elmore BO, Yang C, Ferrara JD, Hooper AB, Wilmot CM Biochemistry. 2007 Jul 17;46(28):8340-9. Epub 2007 Jun 21. PMID:17583915<ref>PMID:17583915</ref>

-	~~===CYTOCHROME P460 FROM NITROSOMONAS EUROPAEA - PROBABLE PHYSIOLOGICAL FORM===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17583915}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2je3]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017583915<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Nitrosomonas europaea]]		[[Category: Nitrosomonas europaea]]
	[[Category: Elmore, B O.]]		[[Category: Elmore, B O.]]

OCA: Protected "2je3" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 14:14:02 GMT

Protected "2je3" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:14, 7 January 2013

OCA at 14:14, 7 January 2013

OCA — Mon, 07 Jan 2013 14:14:00 GMT

←Older revision		Revision as of 14:14, 7 January 2013
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-	{{Seed}}
	[[Image:2je3.png\|left\|200px]]		[[Image:2je3.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2je3", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2je3\| PDB=2je3 \| SCENE= }}		{{STRUCTURE_2je3\| PDB=2je3 \| SCENE= }}

-	===CYTOCHROME P460 FROM NITROSOMONAS EUROPAEA- PROBABLE PHYSIOLOGICAL FORM===	+	===CYTOCHROME P460 FROM NITROSOMONAS EUROPAEA - PROBABLE PHYSIOLOGICAL FORM===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17583915}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17583915 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17583915}}		{{ABSTRACT_PUBMED_17583915}}

	==About this Structure==		==About this Structure==
-	~~2JE3~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA].	+	[[2je3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea Nitrosomonas europaea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JE3 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17583915~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017583915</ref><references group="xtra"/>
	[[Category: Nitrosomonas europaea]]		[[Category: Nitrosomonas europaea]]
	[[Category: Elmore, B O.]]		[[Category: Elmore, B O.]]
Line 35:		Line 23:
	[[Category: Heme p460]]		[[Category: Heme p460]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:33:16 2009''