2jft - Revision history

OCA at 09:37, 9 May 2024

OCA — Thu, 09 May 2024 09:37:19 GMT

←Older revision		Revision as of 09:37, 9 May 2024
Line 3:		Line 3:
	<StructureSection load='2jft' size='340' side='right'caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>		<StructureSection load='2jft' size='340' side='right'caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Mycs2 Mycs2~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JFT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JFT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.08Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jfr\|2jfr]], [[2jfs\|2jfs]]</div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [https://pdbe.org/2jft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [https://www.ebi.ac.uk/pdbsum/2jft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jft ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [https://pdbe.org/2jft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [https://www.ebi.ac.uk/pdbsum/2jft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jft ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0QTQ6_MYCS2 A0QTQ6_MYCS2]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Mycs2~~]]	+	[[Category: Mycolicibacterium smegmatis MC2 155]]
-	[[Category: Alzari~~, P M~~]]	+	[[Category: Alzari PM]]
-	[[Category: Bellinzoni, M]]	+	[[Category: Bellinzoni M]]
-	[[Category: Shepard, W]]	+	[[Category: Shepard W]]
-	[[Category: Wehenkel, A]]	+	[[Category: Wehenkel A]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Manganese]]~~	+
-	~~[[Category: Mycobacterium]]~~	+
-	~~[[Category: Ppm phosphatase]]~~	+
-	~~[[Category: Sulfate~~]]	+

OCA at 11:26, 31 March 2021

OCA — Wed, 31 Mar 2021 11:26:40 GMT

←Older revision		Revision as of 11:26, 31 March 2021
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	<StructureSection load='2jft' size='340' side='right'caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>		<StructureSection load='2jft' size='340' side='right'caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2JFT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JFT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jfr\|2jfr]], [[2jfs\|2jfs]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [~~http~~://pdbe.org/2jft PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2jft PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2jft ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [https://pdbe.org/2jft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [https://www.ebi.ac.uk/pdbsum/2jft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jft ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:13, 23 May 2019

OCA — Thu, 23 May 2019 07:13:06 GMT

←Older revision		Revision as of 07:13, 23 May 2019
Line 1:		Line 1:

	==Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate==		==Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate==
-	<StructureSection load='2jft' size='340' side='right' caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>	+	<StructureSection load='2jft' size='340' side='right'caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JFT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JFT FirstGlance]. <br>
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mycs2]]		[[Category: Mycs2]]
	[[Category: Alzari, P M]]		[[Category: Alzari, P M]]

OCA at 06:42, 11 July 2018

OCA — Wed, 11 Jul 2018 06:42:55 GMT

←Older revision		Revision as of 06:42, 11 July 2018
Line 1:		Line 1:
-	==~~CRYSTAL STRUCTURE OF THE~~ PPM ~~SER~~-~~THR PHOSPHATASE MSPP FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH SULFATE~~==	+
		+	==Crystal structure of the PPM Ser-Thr phosphatase MsPP from Mycobacterium smegmatis in complex with sulfate==
	<StructureSection load='2jft' size='340' side='right' caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>		<StructureSection load='2jft' size='340' side='right' caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [http://pdbe.org/2jft PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [http://www.ebi.ac.uk/pdbsum/2jft PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [http://pdbe.org/2jft PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [http://www.ebi.ac.uk/pdbsum/2jft PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jft ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jf/2jft_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jf/2jft_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 12:42, 7 February 2016

OCA — Sun, 07 Feb 2016 12:42:47 GMT

←Older revision		Revision as of 12:42, 7 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jft ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:36, 10 September 2015

OCA — Thu, 10 Sep 2015 01:36:27 GMT

←Older revision		Revision as of 01:36, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2jft' size='340' side='right' caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>		<StructureSection load='2jft' size='340' side='right' caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mycobacterium_smegmatis Mycobacterium smegmatis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JFT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JFT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [http://www.ebi.ac.uk/pdbsum/2jft PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [http://pdbe.org/2jft PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [http://www.ebi.ac.uk/pdbsum/2jft PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2jft" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mycobacterium smegmatis~~]]	+	[[Category: Mycs2]]
	[[Category: Alzari, P M]]		[[Category: Alzari, P M]]
	[[Category: Bellinzoni, M]]		[[Category: Bellinzoni, M]]

OCA at 15:14, 19 January 2015

OCA — Mon, 19 Jan 2015 15:14:01 GMT

←Older revision		Revision as of 15:14, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JFT FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JFT FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [http://www.ebi.ac.uk/pdbsum/2jft PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [http://www.ebi.ac.uk/pdbsum/2jft PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium smegmatis]]		[[Category: Mycobacterium smegmatis]]
-	[[Category: Alzari, P M.]]	+	[[Category: Alzari, P M]]
-	[[Category: Bellinzoni, M.]]	+	[[Category: Bellinzoni, M]]
-	[[Category: Shepard, W.]]	+	[[Category: Shepard, W]]
-	[[Category: Wehenkel, A.]]	+	[[Category: Wehenkel, A]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Manganese]]		[[Category: Manganese]]

OCA at 08:37, 30 September 2014

OCA — Tue, 30 Sep 2014 08:37:58 GMT

←Older revision		Revision as of 08:37, 30 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2jft.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THE PPM SER-THR PHOSPHATASE MSPP FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH SULFATE==
		+	<StructureSection load='2jft' size='340' side='right' caption='[[2jft]], [[Resolution\|resolution]] 1.08Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JFT FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2jfr\|2jfr]], [[2jfs\|2jfs]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jft OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jft RCSB], [http://www.ebi.ac.uk/pdbsum/2jft PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jf/2jft_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Serine/threonine-specific phosphatases (PPs) represent, after protein tyrosine phosphatases, the second major class of enzymes that catalyze the dephosphorylation of proteins. They are classed in two large families, known as PPP and PPM, on the basis of sequence similarities, metal ion dependence, and inhibitor sensitivity. Despite their wide species distribution and broad physiological roles, the catalytic mechanism of PPM phosphatases has been primarily inferred from studies of a single enzyme, human PP2Calpha. Here, we report the biochemical characterization and the atomic resolution structures of a soluble PPM phosphatase from the saprophyte Mycobacterium smegmatis in complex with different ligands. The structures provide putative snapshots along the catalytic cycle, which support an associative reaction mechanism that differs in some important aspects from the currently accepted model and reinforces the hypothesis of convergent evolution in PPs.

-	~~{{STRUCTURE_2jft\| PDB=2jft \| SCENE= }}~~	+	Insights into the catalytic mechanism of PPM Ser/Thr phosphatases from the atomic resolution structures of a mycobacterial enzyme.,Bellinzoni M, Wehenkel A, Shepard W, Alzari PM Structure. 2007 Jul;15(7):863-72. PMID:17637345<ref>PMID:17637345</ref>

-	~~===CRYSTAL STRUCTURE OF THE PPM SER-THR PHOSPHATASE MSPP FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH SULFATE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17637345}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2jft]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:017637345<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mycobacterium smegmatis]]		[[Category: Mycobacterium smegmatis]]
	[[Category: Alzari, P M.]]		[[Category: Alzari, P M.]]

OCA: Protected "2jft" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 13:37:34 GMT

Protected "2jft" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:37, 7 January 2013

OCA at 13:37, 7 January 2013

OCA — Mon, 07 Jan 2013 13:37:29 GMT

←Older revision		Revision as of 13:37, 7 January 2013
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-	{{Seed}}
	[[Image:2jft.png\|left\|200px]]		[[Image:2jft.png\|left\|200px]]

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	{{STRUCTURE_2jft\| PDB=2jft \| SCENE= }}		{{STRUCTURE_2jft\| PDB=2jft \| SCENE= }}

	===CRYSTAL STRUCTURE OF THE PPM SER-THR PHOSPHATASE MSPP FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH SULFATE===		===CRYSTAL STRUCTURE OF THE PPM SER-THR PHOSPHATASE MSPP FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH SULFATE===

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-	<!--
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	{{ABSTRACT_PUBMED_17637345}}		{{ABSTRACT_PUBMED_17637345}}

	==About this Structure==		==About this Structure==
-	~~2JFT~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA].	+	[[2jft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFT OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17637345~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017637345</ref><references group="xtra"/>
	[[Category: Mycobacterium smegmatis]]		[[Category: Mycobacterium smegmatis]]
	[[Category: Alzari, P M.]]		[[Category: Alzari, P M.]]
Line 34:		Line 22:
	[[Category: Ppm phosphatase]]		[[Category: Ppm phosphatase]]
	[[Category: Sulfate]]		[[Category: Sulfate]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:53:03 2009''