2jgq - Revision history

OCA at 14:47, 13 December 2023

OCA — Wed, 13 Dec 2023 14:47:41 GMT

←Older revision		Revision as of 14:47, 13 December 2023
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	<StructureSection load='2jgq' size='340' side='right'caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2jgq' size='340' side='right'caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Campylobacter_pylori Campylobacter~~ pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [https://pdbe.org/2jgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [https://www.ebi.ac.uk/pdbsum/2jgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [https://pdbe.org/2jgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [https://www.ebi.ac.uk/pdbsum/2jgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgq ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TPIS_HELPY TPIS_HELPY]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Campylobacter~~ pylori]]	+	[[Category: Helicobacter pylori 26695]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Triose-phosphate isomerase]]~~	+	[[Category: Chu C-H]]
-	[[Category: Chu, C H]]	+	[[Category: Lai Y-J]]
-	[[Category: Lai, Y J]]	+	[[Category: Sun Y-J]]
-	[[Category: Sun, Y J]]	+
-	~~[[Category: Fatty acid biosynthesis]]~~	+
-	~~[[Category: Gluconeogenesis]]~~	+
-	~~[[Category: Glycolysis]]~~	+
-	~~[[Category: Helicobacter pylori]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Lipid synthesis]]~~	+
-	~~[[Category: Pentose shunt]]~~	+
-	~~[[Category: Triosephosphate isomerase~~]]	+

OCA at 08:10, 19 January 2022

OCA — Wed, 19 Jan 2022 08:10:04 GMT

←Older revision		Revision as of 08:10, 19 January 2022
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	<StructureSection load='2jgq' size='340' side='right'caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2jgq' size='340' side='right'caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [~~http~~://pdbe.org/2jgq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2jgq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [https://pdbe.org/2jgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [https://www.ebi.ac.uk/pdbsum/2jgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:50, 15 April 2020

OCA — Wed, 15 Apr 2020 07:50:24 GMT

←Older revision		Revision as of 07:50, 15 April 2020
Line 1:		Line 1:

	==Kinetics and structural properties of triosephosphate isomerase from Helicobacter pylori==		==Kinetics and structural properties of triosephosphate isomerase from Helicobacter pylori==
-	<StructureSection load='2jgq' size='340' side='right' caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='2jgq' size='340' side='right'caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://pdbe.org/2jgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://pdbe.org/2jgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[Triose ~~Phosphate Isomerase~~\|Triose ~~Phosphate Isomerase~~]]	+	*[[Triose phosphate isomerase 3D structures\|Triose phosphate isomerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Campylobacter pylori]]		[[Category: Campylobacter pylori]]
		+	[[Category: Large Structures]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]
	[[Category: Chu, C H]]		[[Category: Chu, C H]]

OCA at 07:06, 11 July 2018

OCA — Wed, 11 Jul 2018 07:06:50 GMT

←Older revision		Revision as of 07:06, 11 July 2018
Line 1:		Line 1:
-	==~~KINETICS AND STRUCTURAL PROPERTIES OF TRIOSEPHOSPHATE ISOMERASE FROM HELICOBACTER PYLORI~~==	+
		+	==Kinetics and structural properties of triosephosphate isomerase from Helicobacter pylori==
	<StructureSection load='2jgq' size='340' side='right' caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2jgq' size='340' side='right' caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://pdbe.org/2jgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://pdbe.org/2jgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jgq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/2jgq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/2jgq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 12:02, 9 February 2016

OCA — Tue, 09 Feb 2016 12:02:53 GMT

←Older revision		Revision as of 12:02, 9 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jgq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:03, 10 September 2015

OCA — Thu, 10 Sep 2015 22:03:29 GMT

←Older revision		Revision as of 22:03, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2jgq' size='340' side='right' caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2jgq' size='340' side='right' caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Helicobacter_pylori Helicobacter~~ pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://pdbe.org/2jgq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2jgq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Helicobacter~~ pylori]]	+	[[Category: Campylobacter pylori]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]
	[[Category: Chu, C H]]		[[Category: Chu, C H]]
Line 40:		Line 41:
	[[Category: Gluconeogenesis]]		[[Category: Gluconeogenesis]]
	[[Category: Glycolysis]]		[[Category: Glycolysis]]
		+	[[Category: Helicobacter pylori]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Lipid synthesis]]		[[Category: Lipid synthesis]]
	[[Category: Pentose shunt]]		[[Category: Pentose shunt]]
	[[Category: Triosephosphate isomerase]]		[[Category: Triosephosphate isomerase]]

OCA at 18:26, 19 January 2015

OCA — Mon, 19 Jan 2015 18:26:50 GMT

←Older revision		Revision as of 18:26, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]
-	[[Category: Chu, C H.]]	+	[[Category: Chu, C H]]
-	[[Category: Lai, Y J.]]	+	[[Category: Lai, Y J]]
-	[[Category: Sun, Y J.]]	+	[[Category: Sun, Y J]]
	[[Category: Fatty acid biosynthesis]]		[[Category: Fatty acid biosynthesis]]
	[[Category: Gluconeogenesis]]		[[Category: Gluconeogenesis]]
	[[Category: Glycolysis]]		[[Category: Glycolysis]]
-	[[Category: Helicobacter pylori]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Lipid synthesis]]		[[Category: Lipid synthesis]]
	[[Category: Pentose shunt]]		[[Category: Pentose shunt]]
	[[Category: Triosephosphate isomerase]]		[[Category: Triosephosphate isomerase]]

OCA at 10:48, 30 September 2014

OCA — Tue, 30 Sep 2014 10:48:18 GMT

←Older revision		Revision as of 10:48, 30 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2jgq\| PDB=2jgq \| SCENE= }}~~	+	==KINETICS AND STRUCTURAL PROPERTIES OF TRIOSEPHOSPHATE ISOMERASE FROM HELICOBACTER PYLORI==
-	===KINETICS AND STRUCTURAL PROPERTIES OF TRIOSEPHOSPHATE ISOMERASE FROM HELICOBACTER PYLORI===	+	<StructureSection load='2jgq' size='340' side='right' caption='[[2jgq]], [[Resolution\|resolution]] 2.30Å' scene=''>
-	~~{{ABSTRACT_PUBMED_17957775}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JGQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=QGA:1-[(3-CYCLOHEXYLPROPANOYL)(2-HYDROXYETHYL)AMINO]-1-DEOXY-D-ALLITOL'>QGA</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jgq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jgq RCSB], [http://www.ebi.ac.uk/pdbsum/2jgq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/2jgq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Triosephosphate isomerase (TIM) catalyzes the interconversion between dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate in the glycolysis-gluconeogenesis metabolism pathway. The Helicobacter pylori TIM gene (HpTIM) was cloned, and HpTIM was expressed and purified. The enzymatic activity of HpTIM for the substrate GAP was determined (K(m) = 3.46 +/- 0.23 mM and k(cat) = 8.8 x 10(4) min(-1)). The crystal structure of HpTIM was determined by molecular replacement at 2.3 A resolution. The overall structure of HpTIM was (beta/alpha)beta(beta/alpha)(6), which resembles the common TIM barrel fold, (beta/alpha)(8); however, a helix is missing after the second beta-strand. The conformation of loop 6 and binding of phosphate ion suggest that the determined structure of HpTIM was in the "closed" state. A highly conserved Arg-Asp salt bridge in the "DX(D/N)G" motif of most TIMs is absent in HpTIM because the sequence of this motif is "(211)SVDG(214)." To determine the significance of this salt bridge to HpTIM, four mutants, including K183S, K183A, D213Q, and D213A, were constructed and characterized. The results suggest that this conserved salt bridge is not essential for the enzymatic activity of HpTIM; however, it might contribute to the conformational stability of HpTIM.

-	~~==About this Structure==~~	+	Kinetic and structural properties of triosephosphate isomerase from Helicobacter pylori.,Chu CH, Lai YJ, Huang H, Sun YJ Proteins. 2008 Apr;71(1):396-406. PMID:17957775<ref>PMID:17957775</ref>
-	~~[[2jgq]] is a 2 chain structure with sequence~~ from ~~[http://en.wikipedia.org/wiki/Helicobacter_pylori~~ Helicobacter pylori]. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2JGQ OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Triose Phosphate Isomerase\|Triose Phosphate Isomerase]]		*[[Triose Phosphate Isomerase\|Triose Phosphate Isomerase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017957775<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
	[[Category: Triose-phosphate isomerase]]		[[Category: Triose-phosphate isomerase]]

OCA at 11:07, 11 March 2013

OCA — Mon, 11 Mar 2013 11:07:53 GMT

←Older revision		Revision as of 11:07, 11 March 2013
Line 1:		Line 1:
-	[[Image:2jgq.png\|left\|200px]]
-
	{{STRUCTURE_2jgq\| PDB=2jgq \| SCENE= }}		{{STRUCTURE_2jgq\| PDB=2jgq \| SCENE= }}
-
	===KINETICS AND STRUCTURAL PROPERTIES OF TRIOSEPHOSPHATE ISOMERASE FROM HELICOBACTER PYLORI===		===KINETICS AND STRUCTURAL PROPERTIES OF TRIOSEPHOSPHATE ISOMERASE FROM HELICOBACTER PYLORI===
-
	{{ABSTRACT_PUBMED_17957775}}		{{ABSTRACT_PUBMED_17957775}}

OCA at 13:46, 20 October 2012

OCA — Sat, 20 Oct 2012 13:46:18 GMT

←Older revision		Revision as of 13:46, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2jgq]] is a 2 chain structure ~~of [[Triose Phosphate Isomerase]]~~ with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA].	+	[[2jgq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JGQ OCA].

	==See Also==		==See Also==