2jmc - Revision history

OCA at 10:06, 20 December 2023

OCA — Wed, 20 Dec 2023 10:06:58 GMT

←Older revision		Revision as of 10:06, 20 December 2023
Line 1:		Line 1:

	==Chimer between Spc-SH3 and P41==		==Chimer between Spc-SH3 and P41==
-	<StructureSection load='2jmc' size='340' side='right'caption='[[2jmc~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2jmc' size='340' side='right'caption='[[2jmc]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Chick Chick~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JMC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JMC FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1tuc\|1tuc]], [[2jma\|2jma]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [https://pdbe.org/2jmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [https://www.ebi.ac.uk/pdbsum/2jmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jmc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [https://pdbe.org/2jmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [https://www.ebi.ac.uk/pdbsum/2jmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jmc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.	+	[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 30:

	==See Also==		==See Also==
-	*[[Spectrin\|Spectrin]]	+	*[[Spectrin 3D structures\|Spectrin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chick~~]]	+	[[Category: Gallus gallus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bruix, M]]	+	[[Category: Bruix M]]
-	[[Category: Candel~~, A M~~]]	+	[[Category: Candel AM]]
-	[[Category: Conejero-Lara, F]]	+	[[Category: Conejero-Lara F]]
-	[[Category: Martinez~~, J C~~]]	+	[[Category: Martinez JC]]
-	[[Category: Nuland~~, N A.J van]]~~	+	[[Category: Van Nuland NAJ]]
-	~~[[Category: Chimer]]~~	+
-	~~[[Category: P41]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Spc-sh3~~]]	+

OCA at 11:28, 31 March 2021

OCA — Wed, 31 Mar 2021 11:28:02 GMT

←Older revision		Revision as of 11:28, 31 March 2021
Line 1:		Line 1:

	==Chimer between Spc-SH3 and P41==		==Chimer between Spc-SH3 and P41==
-	<StructureSection load='2jmc' size='340' side='right' caption='[[2jmc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2jmc' size='340' side='right'caption='[[2jmc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Chick Chick]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2JMC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chick Chick]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JMC FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tuc\|1tuc]], [[2jma\|2jma]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [~~http~~://pdbe.org/2jmc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2jmc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2jmc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [https://pdbe.org/2jmc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [https://www.ebi.ac.uk/pdbsum/2jmc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jmc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.	+	[[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Chick]]		[[Category: Chick]]
		+	[[Category: Large Structures]]
	[[Category: Bruix, M]]		[[Category: Bruix, M]]
	[[Category: Candel, A M]]		[[Category: Candel, A M]]

OCA at 07:06, 11 July 2018

OCA — Wed, 11 Jul 2018 07:06:12 GMT

←Older revision		Revision as of 07:06, 11 July 2018
Line 1:		Line 1:
		+
	==Chimer between Spc-SH3 and P41==		==Chimer between Spc-SH3 and P41==
	<StructureSection load='2jmc' size='340' side='right' caption='[[2jmc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2jmc' size='340' side='right' caption='[[2jmc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [http://pdbe.org/2jmc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [http://www.ebi.ac.uk/pdbsum/2jmc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [http://pdbe.org/2jmc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [http://www.ebi.ac.uk/pdbsum/2jmc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jmc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jm/2jmc_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jm/2jmc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jmc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:25, 11 September 2015

OCA — Fri, 11 Sep 2015 12:25:19 GMT

←Older revision		Revision as of 12:25, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2jmc' size='340' side='right' caption='[[2jmc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2jmc' size='340' side='right' caption='[[2jmc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Gallus_gallus Gallus gallus~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JMC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JMC FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 ~~Gallus gallus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [http://www.ebi.ac.uk/pdbsum/2jmc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [http://pdbe.org/2jmc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [http://www.ebi.ac.uk/pdbsum/2jmc PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~SPTA2_CHICK SPTA2_CHICK~~]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.	+	[[http://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2jmc" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Gallus gallus~~]]	+	[[Category: Chick]]
	[[Category: Bruix, M]]		[[Category: Bruix, M]]
	[[Category: Candel, A M]]		[[Category: Candel, A M]]

OCA at 16:25, 25 December 2014

OCA — Thu, 25 Dec 2014 16:25:04 GMT

←Older revision		Revision as of 16:25, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JMC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JMC FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [http://www.ebi.ac.uk/pdbsum/2jmc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [http://www.ebi.ac.uk/pdbsum/2jmc PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/SPTA2_CHICK SPTA2_CHICK]] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
-	[[Category: Bruix, M.]]	+	[[Category: Bruix, M]]
-	[[Category: Candel, A M.]]	+	[[Category: Candel, A M]]
-	[[Category: Conejero-Lara, F.]]	+	[[Category: Conejero-Lara, F]]
-	[[Category: Martinez, J C.]]	+	[[Category: Martinez, J C]]
-	[[Category: Nuland, N A.J van.]]	+	[[Category: Nuland, N A.J van]]
	[[Category: Chimer]]		[[Category: Chimer]]
	[[Category: P41]]		[[Category: P41]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	[[Category: Spc-sh3]]		[[Category: Spc-sh3]]

OCA at 03:40, 29 September 2014

OCA — Mon, 29 Sep 2014 03:40:58 GMT

←Older revision		Revision as of 03:40, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2jmc.~~png~~\|~~left~~\|200px]]	+	==Chimer between Spc-SH3 and P41==
		+	<StructureSection load='2jmc' size='340' side='right' caption='[[2jmc]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2jmc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JMC FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tuc\|1tuc]], [[2jma\|2jma]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPTAN1, SPTA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jmc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jmc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jmc RCSB], [http://www.ebi.ac.uk/pdbsum/2jmc PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jm/2jmc_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Here we present the high-resolution NMR structure of a chimera (SPCp41) between alpha-spectrin SH3 domain and the decapeptide p41. The tertiary structure mimics perfectly the interactions typically found in SH3-peptide complexes and is remarkably similar to that of the complex between the separate Spc-SH3 domain and ligand p41. Relaxation data confirm the tight binding between the ligand and SH3 part of the chimera. This chimera will serve as a tool for a deeper understanding of the relationship between structure and thermodynamics of binding using a combination of NMR, stability and site-directed mutagenesis studies, which can lead to an effective strategy for ligand design.

-	~~{{STRUCTURE_2jmc\| PDB=2jmc \| SCENE= }}~~	+	The high-resolution NMR structure of a single-chain chimeric protein mimicking a SH3-peptide complex.,Candel AM, Conejero-Lara F, Martinez JC, van Nuland NA, Bruix M FEBS Lett. 2007 Feb 20;581(4):687-92. Epub 2007 Jan 22. PMID:17275816<ref>PMID:17275816</ref>

-	~~===Chimer between Spc-SH3 and P41===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_17275816}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2jmc]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Gallus_gallus Gallus gallus]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA].~~	+

	==See Also==		==See Also==
	*[[Spectrin\|Spectrin]]		*[[Spectrin\|Spectrin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:017275816<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Bruix, M.]]		[[Category: Bruix, M.]]

OCA at 18:52, 20 October 2012

OCA — Sat, 20 Oct 2012 18:52:22 GMT

←Older revision		Revision as of 18:52, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2jmc]] is a 1 chain structure ~~of [[Spectrin]]~~ with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA].	+	[[2jmc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA].

	==See Also==		==See Also==

OCA at 05:32, 27 July 2012

OCA — Fri, 27 Jul 2012 05:32:12 GMT

←Older revision		Revision as of 05:32, 27 July 2012
Line 1:		Line 1:
	[[Image:2jmc.png\|left\|200px]]		[[Image:2jmc.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2jmc", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2jmc\| PDB=2jmc \| SCENE= }}		{{STRUCTURE_2jmc\| PDB=2jmc \| SCENE= }}

	===Chimer between Spc-SH3 and P41===		===Chimer between Spc-SH3 and P41===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_17275816}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 17275816 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_17275816}}		{{ABSTRACT_PUBMED_17275816}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Spectrin]]	+	*[[Spectrin\|Spectrin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~17275816~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:017275816</ref><references group="xtra"/>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Bruix, M.]]		[[Category: Bruix, M.]]

OCA: Protected "2jmc" [edit=sysop:move=sysop]

OCA — Sun, 26 Dec 2010 21:53:45 GMT

Protected "2jmc" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:53, 26 December 2010

OCA at 21:53, 26 December 2010

OCA — Sun, 26 Dec 2010 21:53:43 GMT

←Older revision		Revision as of 21:53, 26 December 2010
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2jmc.png\|left\|200px]]		[[Image:2jmc.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2JMC~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA].	+	[[2jmc]] is a 1 chain structure of [[Spectrin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JMC OCA].
		+
		+	==See Also==
		+	*[[Spectrin]]

	==Reference==		==Reference==
Line 32:		Line 34:
	[[Category: Chimer]]		[[Category: Chimer]]
	[[Category: P41]]		[[Category: P41]]
		+	[[Category: Signaling protein]]
	[[Category: Spc-sh3]]		[[Category: Spc-sh3]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:41:18 2009''