2k0l - Revision history

OCA at 19:08, 29 May 2024

OCA — Wed, 29 May 2024 19:08:33 GMT

←Older revision		Revision as of 19:08, 29 May 2024
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	==NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.==		==NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.==
-	<StructureSection load='2k0l' size='340' side='right'caption='[[2k0l~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2k0l' size='340' side='right'caption='[[2k0l]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus~~ pneumoniae~~" (schroeter 1886) flugge 1886~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0L FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>ompA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~573~~ "~~Bacillus pneumoniae~~" ~~(Schroeter 1886) Flugge 1886])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [https://pdbe.org/2k0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [https://www.ebi.ac.uk/pdbsum/2k0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0l ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [https://pdbe.org/2k0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [https://www.ebi.ac.uk/pdbsum/2k0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/OMPA_KLEPN OMPA_KLEPN]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes (By similarity).	+	[https://www.uniprot.org/uniprot/OMPA_KLEPN OMPA_KLEPN] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Klebsiella pneumoniae]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gervais, V]]	+	[[Category: Gervais V]]
-	[[Category: Lohr, F]]	+	[[Category: Lohr F]]
-	[[Category: Milon, A]]	+	[[Category: Milon A]]
-	[[Category: Piotto, M]]	+	[[Category: Piotto M]]
-	[[Category: Reat, V]]	+	[[Category: Reat V]]
-	[[Category: Renault, M]]	+	[[Category: Renault M]]
-	[[Category: Saurel, O]]	+	[[Category: Saurel O]]
-	~~[[Category: Dhpc micelle]]~~	+
-	~~[[Category: Membrane protein]]~~	+
-	~~[[Category: Ompa]]~~	+
-	~~[[Category: Sidechain]]~~	+
-	~~[[Category: Trosy~~]]	+

OCA at 08:04, 7 April 2021

OCA — Wed, 07 Apr 2021 08:04:32 GMT

←Older revision		Revision as of 08:04, 7 April 2021
Line 1:		Line 1:

	==NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.==		==NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.==
-	<StructureSection load='2k0l' size='340' side='right' caption='[[2k0l]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2k0l' size='340' side='right'caption='[[2k0l]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2K0L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K0L FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [~~http~~://pdbe.org/2k0l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2k0l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0l ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [https://pdbe.org/2k0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [https://www.ebi.ac.uk/pdbsum/2k0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/OMPA_KLEPN OMPA_KLEPN]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes (By similarity).	+	[[https://www.uniprot.org/uniprot/OMPA_KLEPN OMPA_KLEPN]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[C-X-C motif chemokine\|C-X-C motif chemokine]]	+	*[[C-X-C motif chemokine 3D structures\|C-X-C motif chemokine 3D structures]]
-	*[[Porin\|Porin]]	+	*[[Porin 3D structures\|Porin 3D structures]]
	*[[Stromal Derived Factor 1\|Stromal Derived Factor 1]]		*[[Stromal Derived Factor 1\|Stromal Derived Factor 1]]
	== References ==		== References ==
Line 37:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Gervais, V]]		[[Category: Gervais, V]]
	[[Category: Lohr, F]]		[[Category: Lohr, F]]

OCA at 10:37, 18 July 2018

OCA — Wed, 18 Jul 2018 10:37:10 GMT

←Older revision		Revision as of 10:37, 18 July 2018
Line 1:		Line 1:
		+
	==NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.==		==NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.==
	<StructureSection load='2k0l' size='340' side='right' caption='[[2k0l]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2k0l' size='340' side='right' caption='[[2k0l]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0L FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0L FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [http://pdbe.org/2k0l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [http://www.ebi.ac.uk/pdbsum/2k0l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [http://pdbe.org/2k0l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [http://www.ebi.ac.uk/pdbsum/2k0l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k0l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/2k0l_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/2k0l_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 12:54, 7 February 2016

OCA — Sun, 07 Feb 2016 12:54:54 GMT

←Older revision		Revision as of 12:54, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k0l ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:40, 10 September 2015

OCA — Thu, 10 Sep 2015 01:40:55 GMT

←Older revision		Revision as of 01:40, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2k0l' size='340' side='right' caption='[[2k0l]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2k0l' size='340' side='right' caption='[[2k0l]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Klebsiella_pneumoniae Klebsiella~~ pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0L FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 ~~Klebsiella~~ pneumoniae])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [http://www.ebi.ac.uk/pdbsum/2k0l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [http://pdbe.org/2k0l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [http://www.ebi.ac.uk/pdbsum/2k0l PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2k0l" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[C-X-C motif chemokine\|C-X-C motif chemokine]]		*[[C-X-C motif chemokine\|C-X-C motif chemokine]]
		+	*[[Porin\|Porin]]
	*[[Stromal Derived Factor 1\|Stromal Derived Factor 1]]		*[[Stromal Derived Factor 1\|Stromal Derived Factor 1]]
	== References ==		== References ==
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Klebsiella pneumoniae]]
	[[Category: Gervais, V]]		[[Category: Gervais, V]]
	[[Category: Lohr, F]]		[[Category: Lohr, F]]

OCA at 15:15, 24 December 2014

OCA — Wed, 24 Dec 2014 15:15:39 GMT

←Older revision		Revision as of 15:15, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0L FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0L FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [http://www.ebi.ac.uk/pdbsum/2k0l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [http://www.ebi.ac.uk/pdbsum/2k0l PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/OMPA_KLEPN OMPA_KLEPN]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Klebsiella pneumoniae]]		[[Category: Klebsiella pneumoniae]]
-	[[Category: Gervais, V.]]	+	[[Category: Gervais, V]]
-	[[Category: Lohr, F.]]	+	[[Category: Lohr, F]]
-	[[Category: Milon, A.]]	+	[[Category: Milon, A]]
-	[[Category: Piotto, M.]]	+	[[Category: Piotto, M]]
-	[[Category: Reat, V.]]	+	[[Category: Reat, V]]
-	[[Category: Renault, M.]]	+	[[Category: Renault, M]]
-	[[Category: Saurel, O.]]	+	[[Category: Saurel, O]]
	[[Category: Dhpc micelle]]		[[Category: Dhpc micelle]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]

OCA at 05:08, 29 September 2014

OCA — Mon, 29 Sep 2014 05:08:10 GMT

←Older revision		Revision as of 05:08, 29 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2k0l.~~png\|left~~\|200px]]	+	==NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.==
		+	<StructureSection load='2k0l' size='340' side='right' caption='[[2k0l]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K0L FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ompA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k0l RCSB], [http://www.ebi.ac.uk/pdbsum/2k0l PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k0/2k0l_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The three-dimensional structure of the outer membrane protein A from Klebsiella pneumoniae transmembrane domain was determined by NMR.This protein induces specific humoral and cytotoxic responses, and is a potent carrier protein. This is one of the largest integral membrane proteins(210 residues) for which nearly complete resonance assignment, including side chains, has been achieved so far. The methodology rested on the use of 900 MHz 3D and 4D TROSY experiments recorded on a uniformly 15N,13C,2H-labeled sample and on a perdeuterated methyl protonated sample. The structure was refined from 920 experimental constraints, giving an ensemble of 20 best structures with an r.m.s. deviation of 0.54 A for the main chain atoms in the core eight-stranded beta-barrel. The protein dynamics was assessed, in a residue-specific manner, by 1H-15N NOEs (pico- to nanosecond timescale), exchange broadening (millisecond to second) and 1H-2H chemical exchange (hour-weeks).

-	~~{{STRUCTURE_2k0l\| PDB=2k0l \| SCENE= }}~~	+	Solution state NMR structure and dynamics of KpOmpA, a 210 residue transmembrane domain possessing a high potential for immunological applications.,Renault M, Saurel O, Czaplicki J, Demange P, Gervais V, Lohr F, Reat V, Piotto M, Milon A J Mol Biol. 2009 Jan 9;385(1):117-30. Epub 2008 Oct 15. PMID:18952100<ref>PMID:18952100</ref>

-	~~===NMR structure~~ of the ~~transmembrane domain~~ of ~~the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles~~.~~===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_18952100}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2k0l]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA].~~	+

	==See Also==		==See Also==
		+	*[[C-X-C motif chemokine\|C-X-C motif chemokine]]
	*[[Stromal Derived Factor 1\|Stromal Derived Factor 1]]		*[[Stromal Derived Factor 1\|Stromal Derived Factor 1]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:018952100<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Klebsiella pneumoniae]]		[[Category: Klebsiella pneumoniae]]
	[[Category: Gervais, V.]]		[[Category: Gervais, V.]]

OCA at 06:42, 20 October 2012

OCA — Sat, 20 Oct 2012 06:42:54 GMT

←Older revision		Revision as of 06:42, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2k0l]] is a 1 chain structure ~~of [[Stromal Derived Factor 1]]~~ with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA].	+	[[2k0l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA].

	==See Also==		==See Also==

OCA: Protected "2k0l" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 14:04:29 GMT

Protected "2k0l" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:04, 25 July 2012

OCA at 14:04, 25 July 2012

OCA — Wed, 25 Jul 2012 14:04:28 GMT

←Older revision		Revision as of 14:04, 25 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2k0l.png\|left\|200px]]		[[Image:2k0l.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_2k0l\| PDB=2k0l \| SCENE= }}		{{STRUCTURE_2k0l\| PDB=2k0l \| SCENE= }}

	===NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.===		===NMR structure of the transmembrane domain of the Outer Membrane Protein A from Klebsiella pneumoniae in DHPC micelles.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_18952100}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 18952100 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_18952100}}		{{ABSTRACT_PUBMED_18952100}}

	==About this Structure==		==About this Structure==
-	~~2K0L~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA].	+	[[2k0l]] is a 1 chain structure of [[Stromal Derived Factor 1]] with sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K0L OCA].
		+
		+	==See Also==
		+	*[[Stromal Derived Factor 1\|Stromal Derived Factor 1]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~18952100~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:018952100</ref><references group="xtra"/>
	[[Category: Klebsiella pneumoniae]]		[[Category: Klebsiella pneumoniae]]
	[[Category: Gervais, V.]]		[[Category: Gervais, V.]]
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	[[Category: Sidechain]]		[[Category: Sidechain]]
	[[Category: Trosy]]		[[Category: Trosy]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:39:38 2010''