2k9f - Revision history

OCA at 08:13, 7 April 2021

OCA — Wed, 07 Apr 2021 08:13:49 GMT

←Older revision		Revision as of 08:13, 7 April 2021
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	==Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis==		==Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis==
-	<StructureSection load='2k9f' size='340' side='right' caption='[[2k9f]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='2k9f' size='340' side='right'caption='[[2k9f]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2k9f]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Neimd Neimd] and [~~http~~://en.wikipedia.org/wiki/Neimi Neimi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2K9F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2k9f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Neimd Neimd] and [https://en.wikipedia.org/wiki/Neimi Neimi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K9F FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2k0r\|2k0r]], [[2jzs\|2jzs]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2k0r\|2k0r]], [[2jzs\|2jzs]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 NEIMD]), dsbD ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 NEIMI])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 NEIMD]), dsbD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 NEIMI])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [~~http~~://pdbe.org/2k9f PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2k9f PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2k9f ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [https://pdbe.org/2k9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [https://www.ebi.ac.uk/pdbsum/2k9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k9f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MSRAB_NEIMA MSRAB_NEIMA]] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation (By similarity). Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. [[~~http~~://www.uniprot.org/uniprot/DSBD_NEIMB DSBD_NEIMB]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).	+	[[https://www.uniprot.org/uniprot/MSRAB_NEIMA MSRAB_NEIMA]] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation (By similarity). Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. [[https://www.uniprot.org/uniprot/DSBD_NEIMB DSBD_NEIMB]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:

	==See Also==		==See Also==
-	*[[Thiol:disulfide interchange protein\|Thiol:disulfide interchange protein]]	+	*[[Thiol:disulfide interchange protein 3D structures\|Thiol:disulfide interchange protein 3D structures]]
-	*[[Thioredoxin\|Thioredoxin]]	+	*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Neimd]]		[[Category: Neimd]]
	[[Category: Neimi]]		[[Category: Neimi]]

OCA at 10:19, 18 July 2018

OCA — Wed, 18 Jul 2018 10:19:15 GMT

←Older revision		Revision as of 10:19, 18 July 2018
Line 1:		Line 1:
		+
	==Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis==		==Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis==
	<StructureSection load='2k9f' size='340' side='right' caption='[[2k9f]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2k9f' size='340' side='right' caption='[[2k9f]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 NEIMD]), dsbD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 NEIMI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 NEIMD]), dsbD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 NEIMI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [http://pdbe.org/2k9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [http://www.ebi.ac.uk/pdbsum/2k9f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [http://pdbe.org/2k9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [http://www.ebi.ac.uk/pdbsum/2k9f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k9f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k9/2k9f_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k9/2k9f_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k9f ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:04, 11 September 2015

OCA — Fri, 11 Sep 2015 09:04:38 GMT

←Older revision		Revision as of 09:04, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2k9f' size='340' side='right' caption='[[2k9f]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2k9f' size='340' side='right' caption='[[2k9f]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2k9f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a~~] and [http://en.wikipedia.org/wiki/~~Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K9F FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2k9f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimd Neimd] and [http://en.wikipedia.org/wiki/Neimi Neimi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K9F FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2k0r\|2k0r]], [[2jzs\|2jzs]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2k0r\|2k0r]], [[2jzs\|2jzs]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 ~~Neisseria meningitidis serogroup A~~]), dsbD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 ~~Neisseria meningitidis serogroup B~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 NEIMD]), dsbD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 NEIMI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [http://www.ebi.ac.uk/pdbsum/2k9f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [http://pdbe.org/2k9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [http://www.ebi.ac.uk/pdbsum/2k9f PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2k9f" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
		+	*[[Thiol:disulfide interchange protein\|Thiol:disulfide interchange protein]]
	*[[Thioredoxin\|Thioredoxin]]		*[[Thioredoxin\|Thioredoxin]]
	== References ==		== References ==
Line 35:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Neisseria meningitidis serogroup a~~]]	+	[[Category: Neimd]]
-	[[Category: ~~Neisseria meningitidis serogroup b~~]]	+	[[Category: Neimi]]
	[[Category: Protein-disulfide reductase]]		[[Category: Protein-disulfide reductase]]
	[[Category: Boschi-Muller, S]]		[[Category: Boschi-Muller, S]]

OCA at 14:14, 25 December 2014

OCA — Thu, 25 Dec 2014 14:14:20 GMT

←Older revision		Revision as of 14:14, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2k9f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K9F FirstGlance]. <br>		<table><tr><td colspan='2'>[[2k9f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K9F FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2k0r\|2k0r]], [[2jzs\|2jzs]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2k0r\|2k0r]], [[2jzs\|2jzs]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 Neisseria meningitidis serogroup A]), dsbD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 Neisseria meningitidis serogroup B])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 Neisseria meningitidis serogroup A]), dsbD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 Neisseria meningitidis serogroup B])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [http://www.ebi.ac.uk/pdbsum/2k9f PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [http://www.ebi.ac.uk/pdbsum/2k9f PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MSRAB_NEIMA MSRAB_NEIMA]] Has an important function as a repair enzyme for proteins that have been inactivated by oxidation (By similarity). Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. [[http://www.uniprot.org/uniprot/DSBD_NEIMB DSBD_NEIMB]] Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 38:
	[[Category: Neisseria meningitidis serogroup b]]		[[Category: Neisseria meningitidis serogroup b]]
	[[Category: Protein-disulfide reductase]]		[[Category: Protein-disulfide reductase]]
-	[[Category: Boschi-Muller, S.]]	+	[[Category: Boschi-Muller, S]]
-	[[Category: Branlant, G.]]	+	[[Category: Branlant, G]]
-	[[Category: Cung, M.]]	+	[[Category: Cung, M]]
-	[[Category: Jacob, C.]]	+	[[Category: Jacob, C]]
-	[[Category: Quinternet, M.]]	+	[[Category: Quinternet, M]]
-	[[Category: Selme, L.]]	+	[[Category: Selme, L]]
-	[[Category: Tsan, P.]]	+	[[Category: Tsan, P]]
	[[Category: Cytochrome c-type biogenesis]]		[[Category: Cytochrome c-type biogenesis]]
	[[Category: Docking]]		[[Category: Docking]]

OCA at 05:33, 29 September 2014

OCA — Mon, 29 Sep 2014 05:33:32 GMT

←Older revision		Revision as of 05:33, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2k9f.~~png~~\|~~left~~\|200px]]	+	==Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis==
		+	<StructureSection load='2k9f' size='340' side='right' caption='[[2k9f]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2k9f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K9F FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2k0r\|2k0r]], [[2jzs\|2jzs]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">msrAB, pilB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=65699 Neisseria meningitidis serogroup A]), dsbD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=491 Neisseria meningitidis serogroup B])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-disulfide_reductase Protein-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.8 1.8.1.8] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k9f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2k9f RCSB], [http://www.ebi.ac.uk/pdbsum/2k9f PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k9/2k9f_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	DsbD transmembrane protein dispatches electrons to periplasmic Trx/DsbE-like partners via specific interactions with its N-terminal domain, nDsbD. In the present study, PilB N-terminal domain (NterPilB) is shown to efficiently accept electrons coming from nDsbD from Neisseria meningitidis. Using an NMR-driven docking approach, we have modeled the structure of a mixed disulfide complex between NterPilB and nDsbD. We show the needed opening of nDsbD cap-loop whereas NterPilB FLHE loop does not seem essential in the formation and stabilization of the complex. Relaxation analysis performed on backbone amide groups highlights a kind of dynamics transfer from nDsbD cap-loop on NterPilB alpha1 helix, suggesting that a mobility contribution is required not only for the formation of the mixed disulfide complex, but also for its disruption. Taking into account previous X-ray data on covalent complexes involving nDsbD, a cartoon of interactions between Trx-like partners and nDsbD is proposed that illustrates the adaptability of nDsbD.

-	~~{{STRUCTURE_2k9f\| PDB=2k9f \| SCENE= }}~~	+	Formation of the complex between DsbD and PilB N-terminal domains from Neisseria meningitidis necessitates an adaptability of nDsbD.,Quinternet M, Tsan P, Selme-Roussel L, Jacob C, Boschi-Muller S, Branlant G, Cung MT Structure. 2009 Jul 15;17(7):1024-33. PMID:19604482<ref>PMID:19604482</ref>

-	~~===Structural features~~ of the ~~complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19604482}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2k9f]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en~~.~~wikipedia.org~~/~~wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA].~~	+

	==See Also==		==See Also==
	*[[Thioredoxin\|Thioredoxin]]		*[[Thioredoxin\|Thioredoxin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:019604482<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Neisseria meningitidis serogroup a]]		[[Category: Neisseria meningitidis serogroup a]]
	[[Category: Neisseria meningitidis serogroup b]]		[[Category: Neisseria meningitidis serogroup b]]

OCA at 17:41, 20 October 2012

OCA — Sat, 20 Oct 2012 17:41:55 GMT

←Older revision		Revision as of 17:41, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2k9f]] is a 2 chain structure ~~of [[Thioredoxin]]~~ with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA].	+	[[2k9f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA].

	==See Also==		==See Also==

OCA at 01:44, 27 July 2012

OCA — Fri, 27 Jul 2012 01:44:29 GMT

←Older revision		Revision as of 01:44, 27 July 2012
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	[[Image:2k9f.png\|left\|200px]]		[[Image:2k9f.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2k9f", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2k9f\| PDB=2k9f \| SCENE= }}		{{STRUCTURE_2k9f\| PDB=2k9f \| SCENE= }}

	===Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis===		===Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19604482}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19604482 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_19604482}}		{{ABSTRACT_PUBMED_19604482}}

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	==See Also==		==See Also==
-	*[[Thioredoxin]]	+	*[[Thioredoxin\|Thioredoxin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19604482~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019604482</ref><references group="xtra"/>
	[[Category: Neisseria meningitidis serogroup a]]		[[Category: Neisseria meningitidis serogroup a]]
	[[Category: Neisseria meningitidis serogroup b]]		[[Category: Neisseria meningitidis serogroup b]]

OCA: Protected "2k9f" [edit=sysop:move=sysop]

OCA — Mon, 27 Dec 2010 02:21:42 GMT

Protected "2k9f" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:21, 27 December 2010

OCA at 02:21, 27 December 2010

OCA — Mon, 27 Dec 2010 02:21:41 GMT

←Older revision		Revision as of 02:21, 27 December 2010
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2k9f.png\|left\|200px]]		[[Image:2k9f.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~2K9F~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA].	+	[[2k9f]] is a 2 chain structure of [[Thioredoxin]] with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA].
		+
		+	==See Also==
		+	*[[Thioredoxin]]

	==Reference==		==Reference==
Line 50:		Line 52:
	[[Category: Transmembrane]]		[[Category: Transmembrane]]
	[[Category: Transport]]		[[Category: Transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 3 15:59:40 2009''

OCA at 12:59, 3 September 2009

OCA — Thu, 03 Sep 2009 12:59:42 GMT

←Older revision		Revision as of 12:59, 3 September 2009
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:2k9f.~~jpg~~\|left\|200px]]	+	[[Image:2k9f.png\|left\|200px]]

	<!--		<!--
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	===Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis===		===Structural features of the complex between the DsbD N-terminal and the PilB N-terminal domains from Neisseria meningitidis===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19604482}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19604482 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19604482}}

	==About this Structure==		==About this Structure==
-	2K9F is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA].	+	2K9F is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_a Neisseria meningitidis serogroup a] and [http://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_b Neisseria meningitidis serogroup b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9F OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19604482</ref><references group="xtra"/>
	[[Category: Neisseria meningitidis serogroup a]]		[[Category: Neisseria meningitidis serogroup a]]
	[[Category: Neisseria meningitidis serogroup b]]		[[Category: Neisseria meningitidis serogroup b]]
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	[[Category: Transport]]		[[Category: Transport]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed May 20 17~~:47:46 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 3 15:59:40 2009''