2kb8 - Revision history

OCA at 08:14, 7 April 2021

OCA — Wed, 07 Apr 2021 08:14:57 GMT

←Older revision		Revision as of 08:14, 7 April 2021
Line 1:		Line 1:

	==The dynamic alpha-helix structure of micelle-bound human amylin.==		==The dynamic alpha-helix structure of micelle-bound human amylin.==
-	<StructureSection load='2kb8' size='340' side='right' caption='[[2kb8]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>	+	<StructureSection load='2kb8' size='340' side='right'caption='[[2kb8]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [~~http~~://pdbe.org/2kb8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2kb8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2kb8 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [https://pdbe.org/2kb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [https://www.ebi.ac.uk/pdbsum/2kb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kb8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.	+	[[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Alexandrescu, A T]]		[[Category: Alexandrescu, A T]]
	[[Category: Patil, S M]]		[[Category: Patil, S M]]

OCA at 10:16, 18 July 2018

OCA — Wed, 18 Jul 2018 10:16:22 GMT

←Older revision		Revision as of 10:16, 18 July 2018
Line 1:		Line 1:
		+
	==The dynamic alpha-helix structure of micelle-bound human amylin.==		==The dynamic alpha-helix structure of micelle-bound human amylin.==
	<StructureSection load='2kb8' size='340' side='right' caption='[[2kb8]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>		<StructureSection load='2kb8' size='340' side='right' caption='[[2kb8]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [http://pdbe.org/2kb8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kb8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [http://pdbe.org/2kb8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kb8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kb8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kb/2kb8_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kb/2kb8_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 42:		Line 43:
	[[Category: Iapp]]		[[Category: Iapp]]
	[[Category: Micelle-bound]]		[[Category: Micelle-bound]]
		+	[[Category: Polymorphism]]
	[[Category: Secreted]]		[[Category: Secreted]]
	[[Category: Type ii diabetes]]		[[Category: Type ii diabetes]]

OCA at 16:14, 7 February 2016

OCA — Sun, 07 Feb 2016 16:14:50 GMT

←Older revision		Revision as of 16:14, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kb8 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:08, 10 September 2015

OCA — Thu, 10 Sep 2015 03:08:16 GMT

←Older revision		Revision as of 03:08, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2kb8' size='340' side='right' caption='[[2kb8]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>		<StructureSection load='2kb8' size='340' side='right' caption='[[2kb8]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kb8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [http://pdbe.org/2kb8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kb8 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2kb8" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Alexandrescu, A T]]		[[Category: Alexandrescu, A T]]
	[[Category: Patil, S M]]		[[Category: Patil, S M]]

OCA at 16:36, 24 December 2014

OCA — Wed, 24 Dec 2014 16:36:24 GMT

←Older revision		Revision as of 16:36, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kb8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kb8 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN]] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Alexandrescu, A T.]]	+	[[Category: Alexandrescu, A T]]
-	[[Category: Patil, S M.]]	+	[[Category: Patil, S M]]
-	[[Category: Sheftic, S R.]]	+	[[Category: Sheftic, S R]]
-	[[Category: Xu, S.]]	+	[[Category: Xu, S]]
	[[Category: Amidation]]		[[Category: Amidation]]
	[[Category: Amyloid]]		[[Category: Amyloid]]

OCA at 10:24, 30 September 2014

OCA — Tue, 30 Sep 2014 10:24:16 GMT

←Older revision		Revision as of 10:24, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2kb8.~~png\|left~~\|200px]]	+	==The dynamic alpha-helix structure of micelle-bound human amylin.==
		+	<StructureSection load='2kb8' size='340' side='right' caption='[[2kb8]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KB8 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">IAPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kb8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kb8 RCSB], [http://www.ebi.ac.uk/pdbsum/2kb8 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kb/2kb8_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Amylin is an endocrine hormone that regulates metabolism. In patients afflicted with type 2 diabetes, amylin is found in fibrillar deposits in the pancreas. Membranes are thought to facilitate the aggregation of amylin, and membrane-bound oligomers may be responsible for the islet beta-cell toxicity that develops during type 2 diabetes. To better understand the structural basis for the interactions between amylin and membranes, we determined the NMR structure of human amylin bound to SDS micelles. The first four residues in the structure are constrained to form a hairpin loop by the single disulfide bond in amylin. The last nine residues near the C terminus are unfolded. The core of the structure is an alpha-helix that runs from about residues 5-28. A distortion or kink near residues 18-22 introduces pliancy in the angle between the N- and C-terminal segments of the alpha-helix. Mobility, as determined by (15)N relaxation experiments, increases from the N to the C terminus and is strongly correlated with the accessibility of the polypeptide to spin probes in the solution phase. The spin probe data suggest that the segment between residues 5 and 17 is positioned within the hydrophobic lipid environment, whereas the amyloidogenic segment between residues 20 and 29 is at the interface between the lipid and solvent. This orientation may direct the aggregation of amylin on membranes, whereas coupling between the two segments may mediate the transition to a toxic structure.

-	~~{{STRUCTURE_2kb8\| PDB=2kb8 \| SCENE= }}~~	+	Dynamic alpha-helix structure of micelle-bound human amylin.,Patil SM, Xu S, Sheftic SR, Alexandrescu AT J Biol Chem. 2009 May 1;284(18):11982-91. Epub 2009 Feb 24. PMID:19244249<ref>PMID:19244249</ref>

-	~~===The dynamic alpha-helix structure~~ of ~~micelle-bound human amylin~~.~~===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19244249}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2kb8]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019244249<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Alexandrescu, A T.]]		[[Category: Alexandrescu, A T.]]

OCA: Protected "2kb8" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 14:52:15 GMT

Protected "2kb8" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:52, 7 January 2013

OCA at 14:52, 7 January 2013

OCA — Mon, 07 Jan 2013 14:52:10 GMT

←Older revision		Revision as of 14:52, 7 January 2013
Line 1:		Line 1:
-	{{Seed}}
	[[Image:2kb8.png\|left\|200px]]		[[Image:2kb8.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2kb8", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2kb8\| PDB=2kb8 \| SCENE= }}		{{STRUCTURE_2kb8\| PDB=2kb8 \| SCENE= }}

	===The dynamic alpha-helix structure of micelle-bound human amylin.===		===The dynamic alpha-helix structure of micelle-bound human amylin.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19244249}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19244249 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_19244249}}		{{ABSTRACT_PUBMED_19244249}}

	==About this Structure==		==About this Structure==
-	~~2KB8~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA].	+	[[2kb8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19244249~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019244249</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Alexandrescu, A T.]]		[[Category: Alexandrescu, A T.]]
Line 35:		Line 23:
	[[Category: Iapp]]		[[Category: Iapp]]
	[[Category: Micelle-bound]]		[[Category: Micelle-bound]]
-	[[Category: Polymorphism]]
	[[Category: Secreted]]		[[Category: Secreted]]
	[[Category: Type ii diabetes]]		[[Category: Type ii diabetes]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 22:14:30 2009''

OCA at 19:14, 10 June 2009

OCA — Wed, 10 Jun 2009 19:14:31 GMT

←Older revision		Revision as of 19:14, 10 June 2009
Line 12:		Line 12:
	===The dynamic alpha-helix structure of micelle-bound human amylin.===		===The dynamic alpha-helix structure of micelle-bound human amylin.===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_19244249}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 19244249 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_19244249}}

	==About this Structure==		==About this Structure==
-	2KB8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full ~~experimental~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA].	+	2KB8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:19244249</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Alexandrescu, A T.]]		[[Category: Alexandrescu, A T.]]
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	[[Category: Type ii diabetes]]		[[Category: Type ii diabetes]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 20:35:48 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 22:14:30 2009''

OCA at 17:31, 10 June 2009

OCA — Wed, 10 Jun 2009 17:31:38 GMT

←Older revision		Revision as of 17:31, 10 June 2009
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	===The dynamic alpha-helix structure of micelle-bound human amylin.===		===The dynamic alpha-helix structure of micelle-bound human amylin.===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19244249}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 19244249 is the PubMed ID number.
-	-->
-	{{ABSTRACT_PUBMED_19244249}}

	==About this Structure==		==About this Structure==
-	2KB8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA].	+	2KB8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KB8 OCA].
-		+
-	~~==Reference==~~	+
-	~~<ref group="xtra">PMID:19244249</ref><references group="xtra"/>~~	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Alexandrescu, A T.]]		[[Category: Alexandrescu, A T.]]
Line 39:		Line 30:
	[[Category: Type ii diabetes]]		[[Category: Type ii diabetes]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 18:16:44 2009''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 20:35:48 2009''