2kdy - Revision history

OCA at 09:38, 22 May 2024

OCA — Wed, 22 May 2024 09:38:02 GMT

←Older revision		Revision as of 09:38, 22 May 2024
Line 1:		Line 1:

	==NMR structure of LP2086-B01==		==NMR structure of LP2086-B01==
-	<StructureSection load='2kdy' size='340' side='right'caption='[[2kdy~~]], [[NMR_Ensembles_of_Models \| 17 NMR models~~]]' scene=''>	+	<StructureSection load='2kdy' size='340' side='right'caption='[[2kdy]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis~~ meningitidis~~" (sic) weichselbaum 1887~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KDY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KDY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [https://pdbe.org/2kdy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [https://www.ebi.ac.uk/pdbsum/2kdy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kdy ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [https://pdbe.org/2kdy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [https://www.ebi.ac.uk/pdbsum/2kdy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kdy ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q6VRY4_NEIME Q6VRY4_NEIME]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bentley~~, B E~~]]	+	[[Category: Neisseria meningitidis]]
-	[[Category: Camarda, R]]	+	[[Category: Bentley BE]]
-	[[Category: Dilts~~, D A~~]]	+	[[Category: Camarda R]]
-	[[Category: Fink, P]]	+	[[Category: Dilts DA]]
-	[[Category: Gusarova, V]]	+	[[Category: Fink P]]
-	[[Category: Hoiseth, S]]	+	[[Category: Gusarova V]]
-	[[Category: Jacob, J]]	+	[[Category: Hoiseth S]]
-	[[Category: Lin~~, S L~~]]	+	[[Category: Jacob J]]
-	[[Category: Malakian, K]]	+	[[Category: Lin SL]]
-	[[Category: Mascioni, A]]	+	[[Category: Malakian K]]
-	[[Category: McNeil~~, L K~~]]	+	[[Category: Mascioni A]]
-	[[Category: Mininni, T]]	+	[[Category: McNeil LK]]
-	[[Category: Moy, F]]	+	[[Category: Mininni T]]
-	[[Category: Murphy, E]]	+	[[Category: Moy F]]
-	[[Category: Novikova, E]]	+	[[Category: Murphy E]]
-	[[Category: Sigethy, S]]	+	[[Category: Novikova E]]
-	[[Category: Tsao~~, D H.H~~]]	+	[[Category: Sigethy S]]
-	[[Category: Wen, Y]]	+	[[Category: Tsao DHH]]
-	[[Category: Zlotnick~~, G W]]~~	+	[[Category: Wen Y]]
-	~~[[Category: Beta barrel]]~~	+	[[Category: Zlotnick GW]]
-	~~[[Category: Immune system~~]]	+

OCA at 07:33, 27 January 2022

OCA — Thu, 27 Jan 2022 07:33:46 GMT

←Older revision		Revision as of 07:33, 27 January 2022
Line 3:		Line 3:
	<StructureSection load='2kdy' size='340' side='right'caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>		<StructureSection load='2kdy' size='340' side='right'caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2KDY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KDY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [~~http~~://pdbe.org/2kdy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2kdy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2kdy ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [https://pdbe.org/2kdy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [https://www.ebi.ac.uk/pdbsum/2kdy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kdy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 06:33, 22 April 2020

OCA — Wed, 22 Apr 2020 06:33:49 GMT

←Older revision		Revision as of 06:33, 22 April 2020
Line 1:		Line 1:

	==NMR structure of LP2086-B01==		==NMR structure of LP2086-B01==
-	<StructureSection load='2kdy' size='340' side='right' caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>	+	<StructureSection load='2kdy' size='340' side='right'caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2KDY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2KDY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://pdbe.org/2kdy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kdy ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://pdbe.org/2kdy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kdy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bentley, B E]]		[[Category: Bentley, B E]]
	[[Category: Camarda, R]]		[[Category: Camarda, R]]

OCA at 11:22, 18 July 2018

OCA — Wed, 18 Jul 2018 11:22:59 GMT

←Older revision		Revision as of 11:22, 18 July 2018
Line 1:		Line 1:
		+
	==NMR structure of LP2086-B01==		==NMR structure of LP2086-B01==
	<StructureSection load='2kdy' size='340' side='right' caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>		<StructureSection load='2kdy' size='340' side='right' caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KDY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KDY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://pdbe.org/2kdy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://pdbe.org/2kdy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kdy ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kd/2kdy_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kd/2kdy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kdy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:19, 12 September 2015

OCA — Sat, 12 Sep 2015 00:19:40 GMT

←Older revision		Revision as of 00:19, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2kdy' size='340' side='right' caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>		<StructureSection load='2kdy' size='340' side='right' caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Neisseria_meningitidis Neisseria~~ meningitidis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KDY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplokokkus_intracellularis_meningitidis"_(sic)_weichselbaum_1887 "diplokokkus intracellularis meningitidis" (sic) weichselbaum 1887]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KDY FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://pdbe.org/2kdy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 23:		Line 23:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2kdy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Neisseria meningitidis]]
	[[Category: Bentley, B E]]		[[Category: Bentley, B E]]
	[[Category: Camarda, R]]		[[Category: Camarda, R]]

OCA at 14:36, 19 January 2015

OCA — Mon, 19 Jan 2015 14:36:48 GMT

←Older revision		Revision as of 14:36, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KDY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KDY FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Neisseria meningitidis]]		[[Category: Neisseria meningitidis]]
-	[[Category: Bentley, B E.]]	+	[[Category: Bentley, B E]]
-	[[Category: Camarda, R.]]	+	[[Category: Camarda, R]]
-	[[Category: Dilts, D A.]]	+	[[Category: Dilts, D A]]
-	[[Category: Fink, P.]]	+	[[Category: Fink, P]]
-	[[Category: Gusarova, V.]]	+	[[Category: Gusarova, V]]
-	[[Category: Hoiseth, S.]]	+	[[Category: Hoiseth, S]]
-	[[Category: Jacob, J.]]	+	[[Category: Jacob, J]]
-	[[Category: Lin, S L.]]	+	[[Category: Lin, S L]]
-	[[Category: Malakian, K.]]	+	[[Category: Malakian, K]]
-	[[Category: Mascioni, A.]]	+	[[Category: Mascioni, A]]
-	[[Category: McNeil, L K.]]	+	[[Category: McNeil, L K]]
-	[[Category: Mininni, T.]]	+	[[Category: Mininni, T]]
-	[[Category: Moy, F.]]	+	[[Category: Moy, F]]
-	[[Category: Murphy, E.]]	+	[[Category: Murphy, E]]
-	[[Category: Novikova, E.]]	+	[[Category: Novikova, E]]
-	[[Category: Sigethy, S.]]	+	[[Category: Sigethy, S]]
-	[[Category: Tsao, D H.H.]]	+	[[Category: Tsao, D H.H]]
-	[[Category: Wen, Y.]]	+	[[Category: Wen, Y]]
-	[[Category: Zlotnick, G W.]]	+	[[Category: Zlotnick, G W]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Immune system]]		[[Category: Immune system]]

OCA at 08:22, 30 September 2014

OCA — Tue, 30 Sep 2014 08:22:52 GMT

←Older revision		Revision as of 08:22, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2kdy.~~png\|left~~\|200px]]	+	==NMR structure of LP2086-B01==
		+	<StructureSection load='2kdy' size='340' side='right' caption='[[2kdy]], [[NMR_Ensembles_of_Models \| 17 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KDY FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kdy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kdy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kdy RCSB], [http://www.ebi.ac.uk/pdbsum/2kdy PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kd/2kdy_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	LP2086 is a family of outer membrane lipoproteins from Neisseria meningitidis, which elicits bactericidal antibodies and are currently undergoing human clinical trials in a bivalent formulation where each antigen represents one of the two known LP2086 subfamilies. Here we report the NMR structure of the recombinant LP2086 variant B01, a representative of the LP2086 subfamily B. The structure reveals a novel fold composed of two domains: a "taco-shaped" N-terminal beta-sheet and a C-terminal beta-barrel connected by a linker. The structure in micellar solution is consistent with a model of LP2086 anchored to the outer membrane bilayer through its lipidated N terminus. A long flexible chain connects the folded part of the protein to the lipid anchor and acts as spacer, making both domains accessible to the host immune system. Antibodies broadly reactive against members from both subfamilies have been mapped to the N terminus. A surface of subfamily-defining residues was identified on one face of the protein, offering an explanation for the induction of subfamily-specific bactericidal antibodies.

-	~~{{STRUCTURE_2kdy\| PDB=2kdy \| SCENE= }}~~	+	Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086.,Mascioni A, Bentley BE, Camarda R, Dilts DA, Fink P, Gusarova V, Hoiseth SK, Jacob J, Lin SL, Malakian K, McNeil LK, Mininni T, Moy F, Murphy E, Novikova E, Sigethy S, Wen Y, Zlotnick GW, Tsao DH J Biol Chem. 2009 Mar 27;284(13):8738-46. Epub 2008 Dec 22. PMID:19103601<ref>PMID:19103601</ref>

-	~~===NMR structure~~ of ~~LP2086-B01===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19103601}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2kdy]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Neisseria_meningitidis Neisseria meningitidis]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019103601<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Neisseria meningitidis]]		[[Category: Neisseria meningitidis]]
	[[Category: Bentley, B E.]]		[[Category: Bentley, B E.]]

OCA: Protected "2kdy" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 13:24:51 GMT

Protected "2kdy" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:24, 7 January 2013

OCA at 13:24, 7 January 2013

OCA — Mon, 07 Jan 2013 13:24:49 GMT

←Older revision		Revision as of 13:24, 7 January 2013
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-	{{Seed}}
	[[Image:2kdy.png\|left\|200px]]		[[Image:2kdy.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2kdy", creates the "Structure Box" on the page.
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	{{STRUCTURE_2kdy\| PDB=2kdy \| SCENE= }}		{{STRUCTURE_2kdy\| PDB=2kdy \| SCENE= }}

	===NMR structure of LP2086-B01===		===NMR structure of LP2086-B01===

-
-	<!--
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	{{ABSTRACT_PUBMED_19103601}}		{{ABSTRACT_PUBMED_19103601}}

	==About this Structure==		==About this Structure==
-	~~2KDY~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA].	+	[[2kdy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neisseria_meningitidis Neisseria meningitidis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KDY OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19103601~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019103601</ref><references group="xtra"/>
	[[Category: Neisseria meningitidis]]		[[Category: Neisseria meningitidis]]
	[[Category: Bentley, B E.]]		[[Category: Bentley, B E.]]
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	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Immune system]]		[[Category: Immune system]]
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OCA at 17:11, 8 April 2009

OCA — Wed, 08 Apr 2009 17:11:50 GMT

←Older revision		Revision as of 17:11, 8 April 2009
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-	[[Image:2kdy.~~jpg~~\|left\|200px]]	+	[[Image:2kdy.png\|left\|200px]]

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