2kfk - Revision history

OCA at 19:12, 29 May 2024

OCA — Wed, 29 May 2024 19:12:03 GMT

←Older revision		Revision as of 19:12, 29 May 2024
Line 1:		Line 1:

	==Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain==		==Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain==
-	<StructureSection load='2kfk' size='340' side='right'caption='[[2kfk~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2kfk' size='340' side='right'caption='[[2kfk]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KFK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KFK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [https://pdbe.org/2kfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [https://www.ebi.ac.uk/pdbsum/2kfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfk ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [https://pdbe.org/2kfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [https://www.ebi.ac.uk/pdbsum/2kfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/BEM1_YEAST BEM1_YEAST]] Necessary for cell polarization during vegetative growth. May link the cytoskeleton to morphogenic determinants on the cell surface.<ref>PMID:17460121</ref> [[https://www.uniprot.org/uniprot/CDC24_YEAST CDC24_YEAST]] Promotes the exchange of CDC42-bound GDP by GTP. Controls the polarity of calmodulin, and the calcium regulatory process of bud emergence. CDC24 may be involved in the initial selection and organization of the budding site.	+	[https://www.uniprot.org/uniprot/BEM1_YEAST BEM1_YEAST] Necessary for cell polarization during vegetative growth. May link the cytoskeleton to morphogenic determinants on the cell surface.<ref>PMID:17460121</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Inagaki, F]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Kobashigawa, Y]]	+	[[Category: Inagaki F]]
-	[[Category: Ogura, K]]	+	[[Category: Kobashigawa Y]]
-	[[Category: Tandai, T]]	+	[[Category: Ogura K]]
-	[[Category: Yoshinaga, S]]	+	[[Category: Tandai T]]
-	~~[[Category: Budding]]~~	+	[[Category: Yoshinaga S]]
-	~~[[Category: Pb1]]~~	+
-	~~[[Category: Phox]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Yeast~~]]	+

OCA at 07:34, 27 January 2022

OCA — Thu, 27 Jan 2022 07:34:20 GMT

←Older revision		Revision as of 07:34, 27 January 2022
Line 3:		Line 3:
	<StructureSection load='2kfk' size='340' side='right'caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2kfk' size='340' side='right'caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2KFK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KFK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [~~http~~://pdbe.org/2kfk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2kfk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfk ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [https://pdbe.org/2kfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [https://www.ebi.ac.uk/pdbsum/2kfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/BEM1_YEAST BEM1_YEAST]] Necessary for cell polarization during vegetative growth. May link the cytoskeleton to morphogenic determinants on the cell surface.<ref>PMID:17460121</ref> [[~~http~~://www.uniprot.org/uniprot/CDC24_YEAST CDC24_YEAST]] Promotes the exchange of CDC42-bound GDP by GTP. Controls the polarity of calmodulin, and the calcium regulatory process of bud emergence. CDC24 may be involved in the initial selection and organization of the budding site.	+	[[https://www.uniprot.org/uniprot/BEM1_YEAST BEM1_YEAST]] Necessary for cell polarization during vegetative growth. May link the cytoskeleton to morphogenic determinants on the cell surface.<ref>PMID:17460121</ref> [[https://www.uniprot.org/uniprot/CDC24_YEAST CDC24_YEAST]] Promotes the exchange of CDC42-bound GDP by GTP. Controls the polarity of calmodulin, and the calcium regulatory process of bud emergence. CDC24 may be involved in the initial selection and organization of the budding site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:34, 22 April 2020

OCA — Wed, 22 Apr 2020 06:34:16 GMT

←Older revision		Revision as of 06:34, 22 April 2020
Line 1:		Line 1:

	==Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain==		==Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain==
-	<StructureSection load='2kfk' size='340' side='right' caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2kfk' size='340' side='right'caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2KFK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2KFK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://pdbe.org/2kfk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfk ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://pdbe.org/2kfk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Inagaki, F]]		[[Category: Inagaki, F]]
	[[Category: Kobashigawa, Y]]		[[Category: Kobashigawa, Y]]

OCA at 10:09, 18 July 2018

OCA — Wed, 18 Jul 2018 10:09:57 GMT

←Older revision		Revision as of 10:09, 18 July 2018
Line 1:		Line 1:
		+
	==Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain==		==Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain==
	<StructureSection load='2kfk' size='340' side='right' caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2kfk' size='340' side='right' caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KFK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KFK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://pdbe.org/2kfk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://pdbe.org/2kfk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kfk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kf/2kfk_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kf/2kfk_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kfk ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:16, 12 September 2015

OCA — Sat, 12 Sep 2015 01:16:25 GMT

←Older revision		Revision as of 01:16, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2kfk' size='340' side='right' caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2kfk' size='340' side='right' caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KFK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KFK FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://pdbe.org/2kfk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2kfk" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Saccharomyces cerevisiae~~]]	+	[[Category: Atcc 18824]]
	[[Category: Inagaki, F]]		[[Category: Inagaki, F]]
	[[Category: Kobashigawa, Y]]		[[Category: Kobashigawa, Y]]

OCA at 21:53, 25 December 2014

OCA — Thu, 25 Dec 2014 21:53:07 GMT

←Older revision		Revision as of 21:53, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KFK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KFK FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BEM1_YEAST BEM1_YEAST]] Necessary for cell polarization during vegetative growth. May link the cytoskeleton to morphogenic determinants on the cell surface.<ref>PMID:17460121</ref> [[http://www.uniprot.org/uniprot/CDC24_YEAST CDC24_YEAST]] Promotes the exchange of CDC42-bound GDP by GTP. Controls the polarity of calmodulin, and the calcium regulatory process of bud emergence. CDC24 may be involved in the initial selection and organization of the budding site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Inagaki, F.]]	+	[[Category: Inagaki, F]]
-	[[Category: Kobashigawa, Y.]]	+	[[Category: Kobashigawa, Y]]
-	[[Category: Ogura, K.]]	+	[[Category: Ogura, K]]
-	[[Category: Tandai, T.]]	+	[[Category: Tandai, T]]
-	[[Category: Yoshinaga, S.]]	+	[[Category: Yoshinaga, S]]
	[[Category: Budding]]		[[Category: Budding]]
	[[Category: Pb1]]		[[Category: Pb1]]

OCA at 09:13, 30 September 2014

OCA — Tue, 30 Sep 2014 09:13:03 GMT

←Older revision		Revision as of 09:13, 30 September 2014
Line 1:		Line 1:
-	[[~~Image~~:2kfk.~~png\|left~~\|200px]]	+	==Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain==
		+	<StructureSection load='2kfk' size='340' side='right' caption='[[2kfk]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KFK FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kfk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kfk RCSB], [http://www.ebi.ac.uk/pdbsum/2kfk PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kf/2kfk_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bem1 and Cdc24 of the budding yeast Saccharomyces cerevisiae interact with each other through PB1-PB1 heterodimer formation to regulate the establishment of cell polarity. Here we present the tertiary structure of the heterodimer of Bem1 and Cdc24 PB1 domains determined by NMR spectroscopy. To avoid ambiguity in the NMR spectral analysis, we first prepared a mutant of the Cdc24 PB1 domain that had truncated loops. The mutant provided well dispersed spectra without spectral overlapping, thus allowing unambiguous spectral assignments for structure determination. We confirmed that the loop deletion-mutant was quite similar to the wild-type in both 3D structure and binding affinity. The NMR structure of the heterodimer of the deletion-mutant of Cdc24 PB1 and Bem1 PB1 was determined using a variety of isotope labelled samples including perdeuteration. The interface between the Bem1/Cdc24 PB1 heterodimer was analysed at atomic resolution. Through a comparison with the tertiary structures of other PB1-PB1 heterodimers, we found that conserved electrostatic properties on the molecular surface were commonly used for PB1-PB1 interaction, but hydrophobic interactions were important for cognate interaction in Bem1/Cdc24 PB1 heterodimer formation.

-	~~{{STRUCTURE_2kfk\| PDB=2kfk \| SCENE= }}~~	+	NMR structure of the heterodimer of Bem1 and Cdc24 PB1 domains from Saccharomyces cerevisiae.,Ogura K, Tandai T, Yoshinaga S, Kobashigawa Y, Kumeta H, Ito T, Sumimoto H, Inagaki F J Biochem. 2009 Sep;146(3):317-25. Epub 2009 May 18. PMID:19451149<ref>PMID:19451149</ref>

-	~~===Solution structure~~ of ~~Bem1p PB1 domain complexed with Cdc24p PB1 domain===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_19451149}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2kfk]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:019451149<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Inagaki, F.]]		[[Category: Inagaki, F.]]

OCA: Protected "2kfk" [edit=sysop:move=sysop]

OCA — Mon, 07 Jan 2013 14:08:37 GMT

Protected "2kfk" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:08, 7 January 2013

OCA at 14:08, 7 January 2013

OCA — Mon, 07 Jan 2013 14:08:33 GMT

←Older revision		Revision as of 14:08, 7 January 2013
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-	{{Seed}}
	[[Image:2kfk.png\|left\|200px]]		[[Image:2kfk.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2kfk", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2kfk\| PDB=2kfk \| SCENE= }}		{{STRUCTURE_2kfk\| PDB=2kfk \| SCENE= }}

	===Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain===		===Solution structure of Bem1p PB1 domain complexed with Cdc24p PB1 domain===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_19451149}}, adds the Publication Abstract to the page
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-	-->
	{{ABSTRACT_PUBMED_19451149}}		{{ABSTRACT_PUBMED_19451149}}

	==About this Structure==		==About this Structure==
-	~~2KFK~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA].	+	[[2kfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~19451149~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:019451149</ref><references group="xtra"/>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Inagaki, F.]]		[[Category: Inagaki, F.]]
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	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	[[Category: Yeast]]		[[Category: Yeast]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:30:10 2010''

OCA at 12:30, 28 January 2010

OCA — Thu, 28 Jan 2010 12:30:10 GMT

←Older revision		Revision as of 12:30, 28 January 2010
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	{{Seed}}		{{Seed}}
-	[[Image:2kfk.~~jpg~~\|left\|200px]]	+	[[Image:2kfk.png\|left\|200px]]

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	2KFK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA].	+	2KFK is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFK OCA].

	==Reference==		==Reference==
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	[[Category: Yeast]]		[[Category: Yeast]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct 7 13~~:56:~~21 2009~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:30:10 2010''