2kyj - Revision history

OCA at 08:49, 14 June 2023

OCA — Wed, 14 Jun 2023 08:49:28 GMT

←Older revision		Revision as of 08:49, 14 June 2023
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	==Structure of the scorpion toxin U1-Liotoxin-Lw1a==		==Structure of the scorpion toxin U1-Liotoxin-Lw1a==
-	<StructureSection load='2kyj' size='340' side='right'caption='[[2kyj~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2kyj' size='340' side='right'caption='[[2kyj]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Liocheles_australasiae Liocheles australasiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [https://pdbe.org/2kyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [https://www.ebi.ac.uk/pdbsum/2kyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kyj ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [https://pdbe.org/2kyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [https://www.ebi.ac.uk/pdbsum/2kyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kyj ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TXS2B_HORWA TXS2B_HORWA] Affects the activity of both ryanodine-sensitive calcium-release channels RyR1 and RyR2 with high potency. At lower concentrations the toxin increases full openings of the RyRs, and at higher concentrations it inhibits full openings and induce openings to subconductance levels and reduces the number of full conductance openings. The different actions may be attributed to the toxins binding at different sites on the RyRs, with binding at a high-affinity site mediating the increase in full openings and the induction of subconductance states evoked upon binding to a lower-affinity site. Insect-selective toxin that provokes a dose-dependent contractile paralysis in crickets and blowfly larvae, followed by death.<ref>PMID:21670253</ref> <ref>PMID:23671114</ref>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Alewood, P F~~]]	+	[[Category: Liocheles australasiae]]
-	[[Category: ~~Hill, J~~]]	+	[[Category: Alewood PF]]
-	[[Category: ~~King, G F]]~~	+	[[Category: Hill J]]
-	~~[[Category: Smith,~~ J]]	+	[[Category: King GF]]
-	[[Category: ~~Disulfide-directed hairpin~~]]	+	[[Category: Smith J]]
-	[[Category: ~~Insect toxin]]~~	+
-	~~[[Category: Scorpion toxin]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 07:10, 1 December 2021

OCA — Wed, 01 Dec 2021 07:10:26 GMT

←Older revision		Revision as of 07:10, 1 December 2021
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	<StructureSection load='2kyj' size='340' side='right'caption='[[2kyj]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2kyj' size='340' side='right'caption='[[2kyj]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [~~http~~://pdbe.org/2kyj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2kyj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2kyj ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [https://pdbe.org/2kyj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [https://www.ebi.ac.uk/pdbsum/2kyj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kyj ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 09:45, 26 February 2020

OCA — Wed, 26 Feb 2020 09:45:41 GMT

←Older revision		Revision as of 09:45, 26 February 2020
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	==Structure of the scorpion toxin U1-Liotoxin-Lw1a==		==Structure of the scorpion toxin U1-Liotoxin-Lw1a==
-	<StructureSection load='2kyj' size='340' side='right' caption='[[2kyj]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2kyj' size='340' side='right'caption='[[2kyj]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Alewood, P F]]		[[Category: Alewood, P F]]
	[[Category: Hill, J]]		[[Category: Hill, J]]

OCA at 07:46, 25 July 2018

OCA — Wed, 25 Jul 2018 07:46:42 GMT

←Older revision		Revision as of 07:46, 25 July 2018
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		+
	==Structure of the scorpion toxin U1-Liotoxin-Lw1a==		==Structure of the scorpion toxin U1-Liotoxin-Lw1a==
	<StructureSection load='2kyj' size='340' side='right' caption='[[2kyj]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2kyj' size='340' side='right' caption='[[2kyj]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [http://pdbe.org/2kyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [http://www.ebi.ac.uk/pdbsum/2kyj PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [http://pdbe.org/2kyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [http://www.ebi.ac.uk/pdbsum/2kyj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2kyj ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 23:53, 10 September 2015

OCA — Thu, 10 Sep 2015 23:53:31 GMT

←Older revision		Revision as of 23:53, 10 September 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [http://www.ebi.ac.uk/pdbsum/2kyj PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [http://pdbe.org/2kyj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [http://www.ebi.ac.uk/pdbsum/2kyj PDBsum]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 11:17, 18 December 2014

OCA — Thu, 18 Dec 2014 11:17:27 GMT

←Older revision		Revision as of 11:17, 18 December 2014
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-	~~{{STRUCTURE_2kyj\| PDB=2kyj \| SCENE= }}~~	+	==Structure of the scorpion toxin U1-Liotoxin-Lw1a==
-	===Structure of the scorpion toxin U1-Liotoxin-Lw1a===	+	<StructureSection load='2kyj' size='340' side='right' caption='[[2kyj]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~{{ABSTRACT_PUBMED_021670253}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2KYJ FirstGlance]. <br>
-	==~~About this Structure~~==	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2kyj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2kyj RCSB], [http://www.ebi.ac.uk/pdbsum/2kyj PDBsum]</span></td></tr>
-	[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA].	+	</table>
-	[[Category: Alewood, P F.]]	+	__TOC__
-	[[Category: Hill, J.]]	+	</StructureSection>
-	[[Category: King, G F.]]	+	[[Category: Alewood, P F]]
-	[[Category: Smith, J.]]	+	[[Category: Hill, J]]
		+	[[Category: King, G F]]
		+	[[Category: Smith, J]]
	[[Category: Disulfide-directed hairpin]]		[[Category: Disulfide-directed hairpin]]
	[[Category: Insect toxin]]		[[Category: Insect toxin]]
	[[Category: Scorpion toxin]]		[[Category: Scorpion toxin]]
	[[Category: Toxin]]		[[Category: Toxin]]

OCA at 02:03, 4 April 2013

OCA — Thu, 04 Apr 2013 02:03:48 GMT

←Older revision		Revision as of 02:03, 4 April 2013
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-	[[Image:2kyj.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_2kyj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2kyj\| PDB=2kyj \| SCENE= }}		{{STRUCTURE_2kyj\| PDB=2kyj \| SCENE= }}
-
	===Structure of the scorpion toxin U1-Liotoxin-Lw1a===		===Structure of the scorpion toxin U1-Liotoxin-Lw1a===
-		+	{{ABSTRACT_PUBMED_021670253}}

	==About this Structure==		==About this Structure==
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	[[Category: King, G F.]]		[[Category: King, G F.]]
	[[Category: Smith, J.]]		[[Category: Smith, J.]]
		+	[[Category: Disulfide-directed hairpin]]
		+	[[Category: Insect toxin]]
		+	[[Category: Scorpion toxin]]
		+	[[Category: Toxin]]

OCA: Protected "2kyj" [edit=sysop:move=sysop]

OCA — Wed, 01 Jun 2011 05:48:31 GMT

Protected "2kyj" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:48, 1 June 2011

OCA at 05:48, 1 June 2011

OCA — Wed, 01 Jun 2011 05:48:27 GMT

←Older revision		Revision as of 05:48, 1 June 2011
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-	~~'''Unreleased structure'''~~	+	[[Image:2kyj.jpg\|left\|200px]]

-	The ~~entry 2kyj~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_2kyj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_2kyj\| PDB=2kyj \| SCENE= }}

-	~~Authors: Smith, J., Hill, J., Alewood, P.F., King, G.F.~~	+	===Structure of the scorpion toxin U1-Liotoxin-Lw1a===

-	Description: Structure of the scorpion toxin U1-Liotoxin-Lw1a

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Jun 23 08~~:40:~~27 2010''~~	+	==About this Structure==
		+	[[2kyj]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYJ OCA].
		+	[[Category: Alewood, P F.]]
		+	[[Category: Hill, J.]]
		+	[[Category: King, G F.]]
		+	[[Category: Smith, J.]]

OCA at 04:35, 23 June 2010

OCA — Wed, 23 Jun 2010 04:35:09 GMT

←Older revision		Revision as of 04:35, 23 June 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2kyj is ON HOLD	+	The entry 2kyj is ON HOLD until Paper Publication

	Authors: Smith, J., Hill, J., Alewood, P.F., King, G.F.		Authors: Smith, J., Hill, J., Alewood, P.F., King, G.F.
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	Description: Structure of the scorpion toxin U1-Liotoxin-Lw1a		Description: Structure of the scorpion toxin U1-Liotoxin-Lw1a

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu~~ Jun ~~10 10~~:55:28 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:40:27 2010''