2lhz - Revision history

OCA at 09:00, 14 June 2023

OCA — Wed, 14 Jun 2023 09:00:32 GMT

←Older revision		Revision as of 09:00, 14 June 2023
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	==Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat==		==Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat==
-	<StructureSection load='2lhz' size='340' side='right'caption='[[2lhz~~]], [[NMR_Ensembles_of_Models \| 36 NMR models~~]]' scene=''>	+	<StructureSection load='2lhz' size='340' side='right'caption='[[2lhz]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LHZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene~~></td></tr>~~	+
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</div></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [https://pdbe.org/2lhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [https://www.ebi.ac.uk/pdbsum/2lhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [https://pdbe.org/2lhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [https://www.ebi.ac.uk/pdbsum/2lhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhz ProSAT]</span></td></tr>
	</table>		</table>
Line 23:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Barany, G]]	+	[[Category: Synthetic construct]]
-	[[Category: Borgert, A]]	+	[[Category: Barany G]]
-	[[Category: Cummings, R]]	+	[[Category: Borgert A]]
-	[[Category: Heimburg-Molinaro, J]]	+	[[Category: Cummings R]]
-	[[Category: Ju, T]]	+	[[Category: Heimburg-Molinaro J]]
-	[[Category: Lasanajak, Y]]	+	[[Category: Ju T]]
-	[[Category: Liu, M]]	+	[[Category: Lasanajak Y]]
-	[[Category: Live, D]]	+	[[Category: Liu M]]
-	[[Category: Ragupathi, G]]	+	[[Category: Live D]]
-	[[Category: Smith, D]]	+	[[Category: Ragupathi G]]
-	[[Category: Thompson, P]]	+	[[Category: Smith D]]
-	~~[[Category: Glycosylation]]~~	+	[[Category: Thompson P]]
-	~~[[Category: Sugar binding protein]]~~	+
-	~~[[Category: Tn antigen~~]]	+

OCA at 13:21, 4 May 2022

OCA — Wed, 04 May 2022 13:21:16 GMT

←Older revision		Revision as of 13:21, 4 May 2022
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	<StructureSection load='2lhz' size='340' side='right'caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>		<StructureSection load='2lhz' size='340' side='right'caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LHZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [~~http~~://pdbe.org/2lhz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lhz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [https://pdbe.org/2lhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [https://www.ebi.ac.uk/pdbsum/2lhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:05, 6 May 2020

OCA — Wed, 06 May 2020 07:05:00 GMT

←Older revision		Revision as of 07:05, 6 May 2020
Line 1:		Line 1:

	==Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat==		==Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat==
-	<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>	+	<StructureSection load='2lhz' size='340' side='right'caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LHZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://pdbe.org/2lhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://pdbe.org/2lhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Barany, G]]		[[Category: Barany, G]]
	[[Category: Borgert, A]]		[[Category: Borgert, A]]

OCA at 19:29, 1 August 2018

OCA — Wed, 01 Aug 2018 19:29:27 GMT

←Older revision		Revision as of 19:29, 1 August 2018
Line 1:		Line 1:
		+
	==Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat==		==Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat==
	<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>		<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://pdbe.org/2lhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://pdbe.org/2lhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lhz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:39, 11 September 2015

OCA — Fri, 11 Sep 2015 01:39:24 GMT

←Older revision		Revision as of 01:39, 11 September 2015
Line 6:		Line 6:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://pdbe.org/2lhz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2lhz" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:06, 22 December 2014

OCA — Mon, 22 Dec 2014 05:06:53 GMT

←Older revision		Revision as of 05:06, 22 December 2014
Line 2:		Line 2:
	<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>		<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. <br>	+	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LHZ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>
-	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span></td></tr>
-	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 14:
	Deciphering structural elements of mucin glycoprotein recognition.,Borgert A, Heimburg-Molinaro J, Song X, Lasanajak Y, Ju T, Liu M, Thompson P, Ragupathi G, Barany G, Smith DF, Cummings RD, Live D ACS Chem Biol. 2012 Jun 15;7(6):1031-9. Epub 2012 Apr 9. PMID:22444368<ref>PMID:22444368</ref>		Deciphering structural elements of mucin glycoprotein recognition.,Borgert A, Heimburg-Molinaro J, Song X, Lasanajak Y, Ju T, Liu M, Thompson P, Ragupathi G, Barany G, Smith DF, Cummings RD, Live D ACS Chem Biol. 2012 Jun 15;7(6):1031-9. Epub 2012 Apr 9. PMID:22444368<ref>PMID:22444368</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Barany, G.]]	+	[[Category: Barany, G]]
-	[[Category: Borgert, A.]]	+	[[Category: Borgert, A]]
-	[[Category: Cummings, R.]]	+	[[Category: Cummings, R]]
-	[[Category: Heimburg-Molinaro, J.]]	+	[[Category: Heimburg-Molinaro, J]]
-	[[Category: Ju, T.]]	+	[[Category: Ju, T]]
-	[[Category: Lasanajak, Y.]]	+	[[Category: Lasanajak, Y]]
-	[[Category: Liu, M.]]	+	[[Category: Liu, M]]
-	[[Category: Live, D.]]	+	[[Category: Live, D]]
-	[[Category: Ragupathi, G.]]	+	[[Category: Ragupathi, G]]
-	[[Category: Smith, D.]]	+	[[Category: Smith, D]]
-	[[Category: Thompson, P.]]	+	[[Category: Thompson, P]]
	[[Category: Glycosylation]]		[[Category: Glycosylation]]
	[[Category: Sugar binding protein]]		[[Category: Sugar binding protein]]
	[[Category: Tn antigen]]		[[Category: Tn antigen]]

OCA at 09:50, 1 May 2014

OCA — Thu, 01 May 2014 09:50:33 GMT

←Older revision		Revision as of 09:50, 1 May 2014
Line 2:		Line 2:
	<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>		<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. <br>	+	<table><tr><td colspan='2'>[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. <br>
-	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene><br>	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene><br>
-	<b>[[Non-Standard_Residue\|NonStd Res:]]</b> <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene><br>	+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<b>[[Related_structure\|Related:]]</b> [[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]<br>	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]</td></tr>
-	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span><br>	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
	Mucin glycoproteins present a complex structural landscape arising from the multiplicity of glycosylation patterns afforded by their numerous serine and threonine glycosylation sites, often in clusters, and with variations in respective glycans. To explore the structural complexities in such glycoconjugates, we used NMR to systematically analyze the conformational effects of glycosylation density within a cluster of sites. This allows correlation with molecular recognition through analysis of interactions between these and other glycopeptides, with antibodies, lectins, and sera, using a glycopeptide microarray. Selective antibody interactions with discrete conformational elements, reflecting aspects of the peptide and disposition of GalNAc residues, are observed. Our results help bridge the gap between conformational properties and molecular recognition of these molecules, with implications for their physiological roles. Features of the native mucin motifs impact their relative immunogenicity and are accurately encoded in the antibody binding site, with the conformational integrity being preserved in isolated glycopeptides, as reflected in the antibody binding profile to array components.		Mucin glycoproteins present a complex structural landscape arising from the multiplicity of glycosylation patterns afforded by their numerous serine and threonine glycosylation sites, often in clusters, and with variations in respective glycans. To explore the structural complexities in such glycoconjugates, we used NMR to systematically analyze the conformational effects of glycosylation density within a cluster of sites. This allows correlation with molecular recognition through analysis of interactions between these and other glycopeptides, with antibodies, lectins, and sera, using a glycopeptide microarray. Selective antibody interactions with discrete conformational elements, reflecting aspects of the peptide and disposition of GalNAc residues, are observed. Our results help bridge the gap between conformational properties and molecular recognition of these molecules, with implications for their physiological roles. Features of the native mucin motifs impact their relative immunogenicity and are accurately encoded in the antibody binding site, with the conformational integrity being preserved in isolated glycopeptides, as reflected in the antibody binding profile to array components.
Line 14:		Line 16:

	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>		From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:14, 30 April 2014

OCA — Wed, 30 Apr 2014 10:14:04 GMT

←Older revision		Revision as of 10:14, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. <br>		[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. <br>
-	<b>Related:</b> [[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]<br>	+	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene><br>
		+	<b>[[Non-Standard_Residue\|NonStd Res:]]</b> <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene><br>
		+	<b>[[Related_structure\|Related:]]</b> [[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]<br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lhz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lhz RCSB], [http://www.ebi.ac.uk/pdbsum/2lhz PDBsum]</span><br>
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
	Mucin glycoproteins present a complex structural landscape arising from the multiplicity of glycosylation patterns afforded by their numerous serine and threonine glycosylation sites, often in clusters, and with variations in respective glycans. To explore the structural complexities in such glycoconjugates, we used NMR to systematically analyze the conformational effects of glycosylation density within a cluster of sites. This allows correlation with molecular recognition through analysis of interactions between these and other glycopeptides, with antibodies, lectins, and sera, using a glycopeptide microarray. Selective antibody interactions with discrete conformational elements, reflecting aspects of the peptide and disposition of GalNAc residues, are observed. Our results help bridge the gap between conformational properties and molecular recognition of these molecules, with implications for their physiological roles. Features of the native mucin motifs impact their relative immunogenicity and are accurately encoded in the antibody binding site, with the conformational integrity being preserved in isolated glycopeptides, as reflected in the antibody binding profile to array components.		Mucin glycoproteins present a complex structural landscape arising from the multiplicity of glycosylation patterns afforded by their numerous serine and threonine glycosylation sites, often in clusters, and with variations in respective glycans. To explore the structural complexities in such glycoconjugates, we used NMR to systematically analyze the conformational effects of glycosylation density within a cluster of sites. This allows correlation with molecular recognition through analysis of interactions between these and other glycopeptides, with antibodies, lectins, and sera, using a glycopeptide microarray. Selective antibody interactions with discrete conformational elements, reflecting aspects of the peptide and disposition of GalNAc residues, are observed. Our results help bridge the gap between conformational properties and molecular recognition of these molecules, with implications for their physiological roles. Features of the native mucin motifs impact their relative immunogenicity and are accurately encoded in the antibody binding site, with the conformational integrity being preserved in isolated glycopeptides, as reflected in the antibody binding profile to array components.

OCA at 08:33, 30 April 2014

OCA — Wed, 30 Apr 2014 08:33:23 GMT

←Older revision		Revision as of 08:33, 30 April 2014
Line 1:		Line 1:
-	[[~~Image:~~2lhz.~~png~~\|~~left~~\|~~200px~~]]	+	==Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat==
		+	<StructureSection load='2lhz' size='340' side='right' caption='[[2lhz]], [[NMR_Ensembles_of_Models \| 36 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]. <br>
		+	<b>Related:</b> [[2lhv\|2lhv]], [[2lhw\|2lhw]], [[2lhx\|2lhx]], [[2lhy\|2lhy]], [[2li0\|2li0]], [[2li1\|2li1]], [[2li2\|2li2]]<br>
		+	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
		+	== Publication Abstract from PubMed ==
		+	Mucin glycoproteins present a complex structural landscape arising from the multiplicity of glycosylation patterns afforded by their numerous serine and threonine glycosylation sites, often in clusters, and with variations in respective glycans. To explore the structural complexities in such glycoconjugates, we used NMR to systematically analyze the conformational effects of glycosylation density within a cluster of sites. This allows correlation with molecular recognition through analysis of interactions between these and other glycopeptides, with antibodies, lectins, and sera, using a glycopeptide microarray. Selective antibody interactions with discrete conformational elements, reflecting aspects of the peptide and disposition of GalNAc residues, are observed. Our results help bridge the gap between conformational properties and molecular recognition of these molecules, with implications for their physiological roles. Features of the native mucin motifs impact their relative immunogenicity and are accurately encoded in the antibody binding site, with the conformational integrity being preserved in isolated glycopeptides, as reflected in the antibody binding profile to array components.

-	~~{{STRUCTURE_2lhz\| PDB=2lhz \| SCENE= }}~~	+	Deciphering structural elements of mucin glycoprotein recognition.,Borgert A, Heimburg-Molinaro J, Song X, Lasanajak Y, Ju T, Liu M, Thompson P, Ragupathi G, Barany G, Smith DF, Cummings RD, Live D ACS Chem Biol. 2012 Jun 15;7(6):1031-9. Epub 2012 Apr 9. PMID:22444368<ref>PMID:22444368</ref>

-	~~===Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	== References ==
-	~~{{ABSTRACT_PUBMED_22444368}}~~	+	<references/>
-		+	__TOC__
-	~~==About this Structure==~~	+	</StructureSection>
-	~~[[2lhz]] is~~ a ~~1 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA]~~.	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022444368<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Barany, G.]]		[[Category: Barany, G.]]
	[[Category: Borgert, A.]]		[[Category: Borgert, A.]]

OCA at 04:24, 27 June 2012

OCA — Wed, 27 Jun 2012 04:24:03 GMT

←Older revision		Revision as of 04:24, 27 June 2012
Line 1:		Line 1:
-	[[Image:2lhz.~~jpg~~\|left\|200px]]	+	[[Image:2lhz.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_2lhz", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_2lhz\| PDB=2lhz \| SCENE= }}		{{STRUCTURE_2lhz\| PDB=2lhz \| SCENE= }}

	===Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat===		===Di-O-GalNAc glycosylated Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat===

		+	{{ABSTRACT_PUBMED_22444368}}

	==About this Structure==		==About this Structure==
	[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA].		[[2lhz]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHZ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022444368</ref><references group="xtra"/>
	[[Category: Barany, G.]]		[[Category: Barany, G.]]
	[[Category: Borgert, A.]]		[[Category: Borgert, A.]]