2lmd - Revision history

OCA at 06:56, 1 May 2024

OCA — Wed, 01 May 2024 06:56:24 GMT

←Older revision		Revision as of 06:56, 1 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LMD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LMD FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [https://pdbe.org/2lmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [https://www.ebi.ac.uk/pdbsum/2lmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lmd ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [https://pdbe.org/2lmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [https://www.ebi.ac.uk/pdbsum/2lmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lmd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/PROX1_HUMAN PROX1_HUMAN] May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).		[https://www.uniprot.org/uniprot/PROX1_HUMAN PROX1_HUMAN] May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We have developed an approach for determining NMR structures of proteins over 20 kDa that utilizes sparse distance restraints obtained using transverse relaxation optimized spectroscopy experiments on perdeuterated samples to guide RASREC Rosetta NMR structure calculations. The method was tested on 11 proteins ranging from 15 to 40 kDa, seven of which were previously unsolved. The RASREC Rosetta models were in good agreement with models obtained using traditional NMR methods with larger restraint sets. In five cases X-ray structures were determined or were available, allowing comparison of the accuracy of the Rosetta models and conventional NMR models. In all five cases, the Rosetta models were more similar to the X-ray structures over both the backbone and side-chain conformations than the "best effort" structures determined by conventional methods. The incorporation of sparse distance restraints into RASREC Rosetta allows routine determination of high-quality solution NMR structures for proteins up to 40 kDa, and should be broadly useful in structural biology.
-
-	Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.,Lange OF, Rossi P, Sgourakis NG, Song Y, Lee HW, Aramini JM, Ertekin A, Xiao R, Acton TB, Montelione GT, Baker D Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10873-8. Epub 2012 Jun 25. PMID:22733734<ref>PMID:22733734</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 2lmd" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:07, 15 February 2023

OCA — Wed, 15 Feb 2023 11:07:53 GMT

←Older revision		Revision as of 11:07, 15 February 2023
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	==Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B==		==Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B==
-	<StructureSection load='2lmd' size='340' side='right'caption='[[2lmd~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2lmd' size='340' side='right'caption='[[2lmd]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LMD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LMD FirstGlance]. <br>
-	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [https://pdbe.org/2lmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [https://www.ebi.ac.uk/pdbsum/2lmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lmd ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [https://pdbe.org/2lmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [https://www.ebi.ac.uk/pdbsum/2lmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lmd ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/PROX1_HUMAN PROX1_HUMAN]] May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).	+	[https://www.uniprot.org/uniprot/PROX1_HUMAN PROX1_HUMAN] May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Acton~~, T B~~]]	+	[[Category: Acton TB]]
-	[[Category: Ciccosanti, C]]	+	[[Category: Ciccosanti C]]
-	[[Category: Everett~~, J K~~]]	+	[[Category: Everett JK]]
-	[[Category: Janjua, H]]	+	[[Category: Janjua H]]
-	[[Category: Lange~~, O A~~]]	+	[[Category: Lange OA]]
-	[[Category: Lee, H]]	+	[[Category: Lee H]]
-	[[Category: Maglaqui, M]]	+	[[Category: Maglaqui M]]
-	[[Category: Montelione~~, G T]]~~	+	[[Category: Montelione GT]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Rossi P]]
-	[[Category: Rossi, P]]	+	[[Category: Xiao R]]
-	[[Category: Xiao, R]]	+	[[Category: Zhao L]]
-	[[Category: Zhao, L]]	+
-	~~[[Category: Nesg]]~~	+
-	~~[[Category: PSI, Protein structure initiative]]~~	+
-	~~[[Category: Psi-biology]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 10:13, 12 May 2021

OCA — Wed, 12 May 2021 10:13:43 GMT

←Older revision		Revision as of 10:13, 12 May 2021
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	==Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B==		==Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B==
-	<StructureSection load='2lmd' size='340' side='right' caption='[[2lmd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2lmd' size='340' side='right'caption='[[2lmd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LMD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LMD FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [~~http~~://pdbe.org/2lmd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lmd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lmd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [https://pdbe.org/2lmd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [https://www.ebi.ac.uk/pdbsum/2lmd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lmd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PROX1_HUMAN PROX1_HUMAN]] May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).	+	[[https://www.uniprot.org/uniprot/PROX1_HUMAN PROX1_HUMAN]] May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Acton, T B]]		[[Category: Acton, T B]]
	[[Category: Ciccosanti, C]]		[[Category: Ciccosanti, C]]

OCA at 19:31, 1 August 2018

OCA — Wed, 01 Aug 2018 19:31:14 GMT

←Older revision		Revision as of 19:31, 1 August 2018
Line 1:		Line 1:
		+
	==Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B==		==Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B==
	<StructureSection load='2lmd' size='340' side='right' caption='[[2lmd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lmd' size='340' side='right' caption='[[2lmd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LMD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LMD FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://pdbe.org/2lmd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://pdbe.org/2lmd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lmd ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 00:34, 12 September 2015

OCA — Sat, 12 Sep 2015 00:34:36 GMT

←Older revision		Revision as of 00:34, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2lmd' size='340' side='right' caption='[[2lmd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lmd' size='340' side='right' caption='[[2lmd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LMD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LMD FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://pdbe.org/2lmd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2lmd" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Acton, T B]]		[[Category: Acton, T B]]
	[[Category: Ciccosanti, C]]		[[Category: Ciccosanti, C]]

OCA at 21:29, 25 December 2014

OCA — Thu, 25 Dec 2014 21:29:00 GMT

←Older revision		Revision as of 21:29, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PROX1_HUMAN PROX1_HUMAN]] May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 06:04, 22 December 2014

OCA — Mon, 22 Dec 2014 06:04:56 GMT

←Older revision		Revision as of 06:04, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LMD FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LMD FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 12:		Line 12:
	Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.,Lange OF, Rossi P, Sgourakis NG, Song Y, Lee HW, Aramini JM, Ertekin A, Xiao R, Acton TB, Montelione GT, Baker D Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10873-8. Epub 2012 Jun 25. PMID:22733734<ref>PMID:22733734</ref>		Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.,Lange OF, Rossi P, Sgourakis NG, Song Y, Lee HW, Aramini JM, Ertekin A, Xiao R, Acton TB, Montelione GT, Baker D Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10873-8. Epub 2012 Jun 25. PMID:22733734<ref>PMID:22733734</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 19:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Acton, T B.]]	+	[[Category: Acton, T B]]
-	[[Category: Ciccosanti, C.]]	+	[[Category: Ciccosanti, C]]
-	[[Category: Everett, J K.]]	+	[[Category: Everett, J K]]
-	[[Category: Janjua, H.]]	+	[[Category: Janjua, H]]
-	[[Category: Lange, O A.]]	+	[[Category: Lange, O A]]
-	[[Category: Lee, H.]]	+	[[Category: Lee, H]]
-	[[Category: Maglaqui, M.]]	+	[[Category: Maglaqui, M]]
-	[[Category: Montelione, G T.]]	+	[[Category: Montelione, G T]]
-	[[Category: ~~NESG, Northeast~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Rossi, P.]]	+	[[Category: Rossi, P]]
-	[[Category: Xiao, R.]]	+	[[Category: Xiao, R]]
-	[[Category: Zhao, L.]]	+	[[Category: Zhao, L]]
	[[Category: Nesg]]		[[Category: Nesg]]
-	[[Category: ~~Northeast structural genomics consortium]]~~	+	[[Category: PSI, Protein structure initiative]]
-	~~[[Category:~~ Protein structure initiative]]	+
	[[Category: Psi-biology]]		[[Category: Psi-biology]]
-	[[Category: Structural genomic]]
	[[Category: Transcription]]		[[Category: Transcription]]

OCA at 09:46, 21 May 2014

OCA — Wed, 21 May 2014 09:46:40 GMT

←Older revision		Revision as of 09:46, 21 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2lmd.~~png~~\|~~left\|200px~~]]	+	==Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B==
		+	<StructureSection load='2lmd' size='340' side='right' caption='[[2lmd]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LMD FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PROX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lmd RCSB], [http://www.ebi.ac.uk/pdbsum/2lmd PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have developed an approach for determining NMR structures of proteins over 20 kDa that utilizes sparse distance restraints obtained using transverse relaxation optimized spectroscopy experiments on perdeuterated samples to guide RASREC Rosetta NMR structure calculations. The method was tested on 11 proteins ranging from 15 to 40 kDa, seven of which were previously unsolved. The RASREC Rosetta models were in good agreement with models obtained using traditional NMR methods with larger restraint sets. In five cases X-ray structures were determined or were available, allowing comparison of the accuracy of the Rosetta models and conventional NMR models. In all five cases, the Rosetta models were more similar to the X-ray structures over both the backbone and side-chain conformations than the "best effort" structures determined by conventional methods. The incorporation of sparse distance restraints into RASREC Rosetta allows routine determination of high-quality solution NMR structures for proteins up to 40 kDa, and should be broadly useful in structural biology.

-	~~{{STRUCTURE_2lmd\| PDB=2lmd \| SCENE= }}~~	+	Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.,Lange OF, Rossi P, Sgourakis NG, Song Y, Lee HW, Aramini JM, Ertekin A, Xiao R, Acton TB, Montelione GT, Baker D Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10873-8. Epub 2012 Jun 25. PMID:22733734<ref>PMID:22733734</ref>

-	~~===Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens~~, ~~Northeast Structural Genomics Consortium Target HR4660B===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22733734}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[2lmd]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022733734<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Acton, T B.]]		[[Category: Acton, T B.]]

OCA at 04:29, 18 July 2012

OCA — Wed, 18 Jul 2012 04:29:08 GMT

←Older revision		Revision as of 04:29, 18 July 2012
Line 5:		Line 5:
	===Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B===		===Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B===

		+	{{ABSTRACT_PUBMED_22733734}}

	==About this Structure==		==About this Structure==
	[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA].		[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022733734</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Acton, T B.]]		[[Category: Acton, T B.]]

OCA at 04:28, 27 June 2012

OCA — Wed, 27 Jun 2012 04:28:46 GMT

←Older revision		Revision as of 04:28, 27 June 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2lmd.png\|left\|200px]]

-	~~The entry~~ 2lmd ~~is ON HOLD~~	+	{{STRUCTURE_2lmd\| PDB=2lmd \| SCENE= }}

-	~~Authors: Rossi~~, ~~P., Lange, O.A., Lee, H., Maglaqui, M., Janjua, H., Ciccosanti, C., Zhao, L., Acton, T.B., Xiao, R., Everett, J.K., Montelione, G.T.~~	+	===Minimal Constraints Solution NMR Structure of Prospero Homeobox protein 1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4660B===

-	~~Description: Minimal Constraints Solution NMR~~ Structure ~~of Prospero Homeobox protein~~ 1 from Homo sapiens. Northeast Structural Genomics Consortium ~~Target HR4660B~~.	+
		+	==About this Structure==
		+	[[2lmd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LMD OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Acton, T B.]]
		+	[[Category: Ciccosanti, C.]]
		+	[[Category: Everett, J K.]]
		+	[[Category: Janjua, H.]]
		+	[[Category: Lange, O A.]]
		+	[[Category: Lee, H.]]
		+	[[Category: Maglaqui, M.]]
		+	[[Category: Montelione, G T.]]
		+	[[Category: NESG, Northeast Structural Genomics Consortium.]]
		+	[[Category: Rossi, P.]]
		+	[[Category: Xiao, R.]]
		+	[[Category: Zhao, L.]]
		+	[[Category: Nesg]]
		+	[[Category: Northeast structural genomics consortium]]
		+	[[Category: Protein structure initiative]]
		+	[[Category: Psi-biology]]
		+	[[Category: Structural genomic]]
		+	[[Category: Transcription]]