2lpw - Revision history

OCA at 05:48, 15 May 2024

OCA — Wed, 15 May 2024 05:48:57 GMT

←Older revision		Revision as of 05:48, 15 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LPW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LPW FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [https://pdbe.org/2lpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [https://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [https://pdbe.org/2lpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [https://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:07, 14 June 2023

OCA — Wed, 14 Jun 2023 09:07:53 GMT

←Older revision		Revision as of 09:07, 14 June 2023
Line 1:		Line 1:

	==human CEB25 minisatellite G-quadruplex==		==human CEB25 minisatellite G-quadruplex==
-	<StructureSection load='2lpw' size='340' side='right'caption='[[2lpw~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='2lpw' size='340' side='right'caption='[[2lpw]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LPW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LPW FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2kyo\|2kyo]]</div></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [https://pdbe.org/2lpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [https://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [https://pdbe.org/2lpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [https://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Adrian, M]]	+	[[Category: Adrian M]]
-	[[Category: Amrane, S]]	+	[[Category: Amrane S]]
-	[[Category: Heddi, B]]	+	[[Category: Heddi B]]
-	[[Category: Mergny~~, J L~~]]	+	[[Category: Mergny JL]]
-	[[Category: Nicolas, A]]	+	[[Category: Nicolas A]]
-	[[Category: Phan~~, A T~~]]	+	[[Category: Phan AT]]
-	[[Category: Serero, A]]	+	[[Category: Serero A]]
-	~~[[Category: Dna]]~~	+
-	~~[[Category: G-quadruplex~~]]	+

OCA at 07:53, 9 February 2022

OCA — Wed, 09 Feb 2022 07:53:34 GMT

←Older revision		Revision as of 07:53, 9 February 2022
Line 3:		Line 3:
	<StructureSection load='2lpw' size='340' side='right'caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2lpw' size='340' side='right'caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LPW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LPW FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2kyo\|2kyo]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [~~http~~://pdbe.org/2lpw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [https://pdbe.org/2lpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [https://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:07, 6 May 2020

OCA — Wed, 06 May 2020 07:07:08 GMT

←Older revision		Revision as of 07:07, 6 May 2020
Line 1:		Line 1:

	==human CEB25 minisatellite G-quadruplex==		==human CEB25 minisatellite G-quadruplex==
-	<StructureSection load='2lpw' size='340' side='right' caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='2lpw' size='340' side='right'caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LPW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LPW FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://pdbe.org/2lpw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://pdbe.org/2lpw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Adrian, M]]		[[Category: Adrian, M]]
	[[Category: Amrane, S]]		[[Category: Amrane, S]]

OCA at 20:10, 1 August 2018

OCA — Wed, 01 Aug 2018 20:10:43 GMT

←Older revision		Revision as of 20:10, 1 August 2018
Line 1:		Line 1:
		+
	==human CEB25 minisatellite G-quadruplex==		==human CEB25 minisatellite G-quadruplex==
	<StructureSection load='2lpw' size='340' side='right' caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2lpw' size='340' side='right' caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LPW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LPW FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://pdbe.org/2lpw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://pdbe.org/2lpw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lpw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:36, 11 September 2015

OCA — Fri, 11 Sep 2015 09:36:59 GMT

←Older revision		Revision as of 09:36, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LPW FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LPW FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://pdbe.org/2lpw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2lpw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:22, 3 January 2015

OCA — Sat, 03 Jan 2015 22:22:50 GMT

←Older revision		Revision as of 22:22, 3 January 2015
Line 2:		Line 2:
	<StructureSection load='2lpw' size='340' side='right' caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2lpw' size='340' side='right' caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. <br>	+	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LPW FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>
-	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum]</span></td></tr>
-	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum]</span></td></tr>	+	</table>
-	<table>	+
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 12:
	Formation of Pearl-Necklace Monomorphic G-Quadruplexes in the Human CEB25 Minisatellite.,Amrane S, Adrian M, Heddi B, Serero A, Nicolas A, Mergny JL, Phan AT J Am Chem Soc. 2012 Apr 4;134(13):5807-16. Epub 2012 Mar 26. PMID:22376028<ref>PMID:22376028</ref>		Formation of Pearl-Necklace Monomorphic G-Quadruplexes in the Human CEB25 Minisatellite.,Amrane S, Adrian M, Heddi B, Serero A, Nicolas A, Mergny JL, Phan AT J Am Chem Soc. 2012 Apr 4;134(13):5807-16. Epub 2012 Mar 26. PMID:22376028<ref>PMID:22376028</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 19:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Adrian, M.]]	+	[[Category: Adrian, M]]
-	[[Category: Amrane, S.]]	+	[[Category: Amrane, S]]
-	[[Category: Heddi, B.]]	+	[[Category: Heddi, B]]
-	[[Category: Mergny, J L.]]	+	[[Category: Mergny, J L]]
-	[[Category: Nicolas, A.]]	+	[[Category: Nicolas, A]]
-	[[Category: Phan, A T.]]	+	[[Category: Phan, A T]]
-	[[Category: Serero, A.]]	+	[[Category: Serero, A]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: G-quadruplex]]		[[Category: G-quadruplex]]

OCA at 08:43, 7 May 2014

OCA — Wed, 07 May 2014 08:43:38 GMT

←Older revision		Revision as of 08:43, 7 May 2014
Line 1:		Line 1:
-	[[~~Image:~~2lpw.~~png~~\|~~left~~\|~~200px~~]]	+	==human CEB25 minisatellite G-quadruplex==
		+	<StructureSection load='2lpw' size='340' side='right' caption='[[2lpw]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kyo\|2kyo]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lpw RCSB], [http://www.ebi.ac.uk/pdbsum/2lpw PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	CEB25 is a human minisatellite locus, composed of slightly polymorphic 52-nucleotide (nt) tandem repeats. Genetically, most if not all individuals of the human population are heterozygous, carrying alleles ranging from 0.5 to 20 kb, maintained by mendelian inheritance but also subject to germline instability. To provide insights on the biological role of CEB25, we interrogated its structural features. We report the NMR structure of the G-quadruplex formed by the conserved 26-nt G-rich fragment of the CEB25 motif. In K(+) solution, this sequence forms a propeller-type parallel-stranded G-quadruplex involving a 9-nt central double-chain-reversal loop. This long loop is anchored to the 5'-end of the sequence by an A.T Watson-Crick base pair and a potential G.A noncanonical base pair. These base pairs contribute to the stability of the overall G-quadruplexstructure, as measured by an increase of about 17 kcal/mol in enthalpy or 6 degrees C in melting temperature. Further, we demonstrate that such a monomorphic structure is formed within longer sequence contexts folding into a pearl-necklace structure.

-	<!--	+	Formation of Pearl-Necklace Monomorphic G-Quadruplexes in the Human CEB25 Minisatellite.,Amrane S, Adrian M, Heddi B, Serero A, Nicolas A, Mergny JL, Phan AT J Am Chem Soc. 2012 Apr 4;134(13):5807-16. Epub 2012 Mar 26. PMID:22376028<ref>PMID:22376028</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_2lpw"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_2lpw\| PDB=2lpw \| SCENE= }}~~	+

-	~~===human CEB25 minisatellite G-quadruplex===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_22376028}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22376028 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22376028}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[2lpw]] is a 1 chain structure. Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022376028<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Adrian, M.]]		[[Category: Adrian, M.]]
	[[Category: Amrane, S.]]		[[Category: Amrane, S.]]

OCA at 07:10, 18 April 2012

OCA — Wed, 18 Apr 2012 07:10:02 GMT

←Older revision		Revision as of 07:10, 18 April 2012
Line 11:		Line 11:
	===human CEB25 minisatellite G-quadruplex===		===human CEB25 minisatellite G-quadruplex===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22376028}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22376028 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22376028}}

	==About this Structure==		==About this Structure==
	[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA].		[[2lpw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LPW OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022376028</ref><references group="xtra"/>
	[[Category: Adrian, M.]]		[[Category: Adrian, M.]]
	[[Category: Amrane, S.]]		[[Category: Amrane, S.]]

OCA at 05:26, 4 April 2012

OCA — Wed, 04 Apr 2012 05:26:28 GMT

←Older revision		Revision as of 05:26, 4 April 2012
Line 1:		Line 1:
-	[[Image:2lpw.~~jpg~~\|left\|200px]]	+	[[Image:2lpw.png\|left\|200px]]

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