2lqu - Revision history

OCA at 11:13, 15 February 2023

OCA — Wed, 15 Feb 2023 11:13:24 GMT

←Older revision		Revision as of 11:13, 15 February 2023
Line 1:		Line 1:

	==Structure of decorbin-binding protein A from Borrelia burgdorferi==		==Structure of decorbin-binding protein A from Borrelia burgdorferi==
-	<StructureSection load='2lqu' size='340' side='right'caption='[[2lqu~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='2lqu' size='340' side='right'caption='[[2lqu]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_35210 Atcc 35210~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LQU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi Borreliella burgdorferi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LQU FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 ATCC 35210])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [https://pdbe.org/2lqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [https://www.ebi.ac.uk/pdbsum/2lqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqu ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [https://pdbe.org/2lqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [https://www.ebi.ac.uk/pdbsum/2lqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqu ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DBPA_BORBU DBPA_BORBU]] Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.	+	[https://www.uniprot.org/uniprot/DBPA_BORBU DBPA_BORBU] Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 35210~~]]	+	[[Category: Borreliella burgdorferi]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Wang, X]]	+	[[Category: Wang X]]
-	~~[[Category: Bacterial adhesin]]~~	+
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Gag-binding protein]]~~	+
-	~~[[Category: Helical bundle protein]]~~	+
-	~~[[Category: Lyme disease~~]]	+

OCA at 10:16, 12 May 2021

OCA — Wed, 12 May 2021 10:16:38 GMT

←Older revision		Revision as of 10:16, 12 May 2021
Line 1:		Line 1:

	==Structure of decorbin-binding protein A from Borrelia burgdorferi==		==Structure of decorbin-binding protein A from Borrelia burgdorferi==
-	<StructureSection load='2lqu' size='340' side='right' caption='[[2lqu]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='2lqu' size='340' side='right'caption='[[2lqu]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_35210 Atcc 35210]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LQU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35210 Atcc 35210]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LQU FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 ATCC 35210])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 ATCC 35210])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [~~http~~://pdbe.org/2lqu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lqu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [https://pdbe.org/2lqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [https://www.ebi.ac.uk/pdbsum/2lqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DBPA_BORBU DBPA_BORBU]] Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.	+	[[https://www.uniprot.org/uniprot/DBPA_BORBU DBPA_BORBU]] Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 35210]]		[[Category: Atcc 35210]]
		+	[[Category: Large Structures]]
	[[Category: Wang, X]]		[[Category: Wang, X]]
	[[Category: Bacterial adhesin]]		[[Category: Bacterial adhesin]]

OCA at 19:54, 1 August 2018

OCA — Wed, 01 Aug 2018 19:54:16 GMT

←Older revision		Revision as of 19:54, 1 August 2018
Line 1:		Line 1:
		+
	==Structure of decorbin-binding protein A from Borrelia burgdorferi==		==Structure of decorbin-binding protein A from Borrelia burgdorferi==
	<StructureSection load='2lqu' size='340' side='right' caption='[[2lqu]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2lqu' size='340' side='right' caption='[[2lqu]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35210 Atcc 35210]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LQU FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35210 Atcc 35210]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LQU FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 ATCC 35210])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 ATCC 35210])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [http://pdbe.org/2lqu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [http://www.ebi.ac.uk/pdbsum/2lqu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [http://pdbe.org/2lqu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [http://www.ebi.ac.uk/pdbsum/2lqu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lqu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:58, 10 September 2015

OCA — Thu, 10 Sep 2015 07:58:21 GMT

←Older revision		Revision as of 07:58, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2lqu' size='340' side='right' caption='[[2lqu]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2lqu' size='340' side='right' caption='[[2lqu]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Borrelia_burgdorferi Borrelia burgdorferi~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LQU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35210 Atcc 35210]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LQU FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 ~~Borrelia burgdorferi~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 ATCC 35210])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [http://www.ebi.ac.uk/pdbsum/2lqu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [http://pdbe.org/2lqu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [http://www.ebi.ac.uk/pdbsum/2lqu PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DBPA_BORBU DBPA_BORBU]] Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2lqu" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Borrelia burgdorferi~~]]	+	[[Category: Atcc 35210]]
	[[Category: Wang, X]]		[[Category: Wang, X]]
	[[Category: Bacterial adhesin]]		[[Category: Bacterial adhesin]]

OCA at 06:38, 22 December 2014

OCA — Mon, 22 Dec 2014 06:38:00 GMT

←Older revision		Revision as of 06:38, 22 December 2014
Line 1:		Line 1:
-	[[~~Image:~~2lqu.~~jpg~~\|~~left\|200px~~]]	+	==Structure of decorbin-binding protein A from Borrelia burgdorferi==
		+	<StructureSection load='2lqu' size='340' side='right' caption='[[2lqu]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2lqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi Borrelia burgdorferi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LQU FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_A24, dbpA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=139 Borrelia burgdorferi])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lqu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lqu RCSB], [http://www.ebi.ac.uk/pdbsum/2lqu PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Decorin-binding protein A (DBPA) is an important lipoprotein from the bacterium Borrelia burgdorferi, the causative agent of Lyme disease. The absence of DBPA drastically reduces the pathogenic potential of the bacterium, and biochemical evidence indicates DBPA's interactions with the glycosaminoglycan (GAG) portion of decorin are crucial to its function. We have determined the solution structure of DBPA and studied DBPA's interactions with various forms of GAGs. DBPA is determined to be a helical bundle protein consisting of five helices held together by a strong hydrophobic core. The structure also possesses a basic patch formed by portions of two helices and two flexible linkers. Low-molecular mass heparin-induced chemical shift perturbations for residues in the region as well as increases in signal intensities of select residues in their presence confirm residues in the pocket are perturbed by heparin binding. Dermatan sulfate fragments, the dominant GAG type found on decorin, were shown to have lower affinity than heparin but are still capable of binding DBPA.

-	~~{{STRUCTURE_2lqu\| PDB=2lqu \| SCENE= }}~~	+	Solution structure of decorin-binding protein A from Borrelia burgdorferi.,Wang X Biochemistry. 2012 Oct 23;51(42):8353-62. doi: 10.1021/bi3007093. Epub 2012 Oct, 8. PMID:22985470<ref>PMID:22985470</ref>

-	~~===Structure~~ of ~~decorbin-binding protein A from Borrelia burgdorferi===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22985470}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[2lqu]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Borrelia_burgdorferi Borrelia burgdorferi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA].~~	+	</StructureSection>
	[[Category: Borrelia burgdorferi]]		[[Category: Borrelia burgdorferi]]
-	[[Category: Wang, X.]]	+	[[Category: Wang, X]]
	[[Category: Bacterial adhesin]]		[[Category: Bacterial adhesin]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 08:50, 16 January 2013

OCA — Wed, 16 Jan 2013 08:50:37 GMT

←Older revision		Revision as of 08:50, 16 January 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2lqu.jpg\|left\|200px]]

-	~~The entry~~ 2lqu ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_2lqu\| PDB=2lqu \| SCENE= }}

-	~~Authors: Wang, X.~~	+	===Structure of decorbin-binding protein A from Borrelia burgdorferi===

-	~~Description:~~ Structure ~~of decorbin-binding protein A~~ from Borrelia burgdorferi	+	{{ABSTRACT_PUBMED_22985470}}
		+
		+	==About this Structure==
		+	[[2lqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Borrelia_burgdorferi Borrelia burgdorferi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LQU OCA].
		+	[[Category: Borrelia burgdorferi]]
		+	[[Category: Wang, X.]]
		+	[[Category: Bacterial adhesin]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Gag-binding protein]]
		+	[[Category: Helical bundle protein]]
		+	[[Category: Lyme disease]]

OCA at 07:06, 28 March 2012

OCA — Wed, 28 Mar 2012 07:06:29 GMT

←Older revision		Revision as of 07:06, 28 March 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2lqu is ON HOLD	+	The entry 2lqu is ON HOLD until Paper Publication

	Authors: Wang, X.		Authors: Wang, X.

	Description: Structure of decorbin-binding protein A from Borrelia burgdorferi		Description: Structure of decorbin-binding protein A from Borrelia burgdorferi

OCA: Protected "2lqu" [edit=sysop:move=sysop]

OCA — Wed, 21 Mar 2012 06:58:22 GMT

Protected "2lqu" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:58, 21 March 2012

OCA: New page: '''Unreleased structure''' The entry 2lqu is ON HOLD Authors: Wang, X. Description: Structure of decorbin-binding protein A from Borrelia burgdorferi

OCA — Wed, 21 Mar 2012 06:58:21 GMT

New page: '''Unreleased structure''' The entry 2lqu is ON HOLD Authors: Wang, X. Description: Structure of decorbin-binding protein A from Borrelia burgdorferi

New page

'''Unreleased structure'''

The entry 2lqu is ON HOLD

Authors: Wang, X.

Description: Structure of decorbin-binding protein A from Borrelia burgdorferi