2lt8 - Revision history

OCA at 09:10, 14 June 2023

OCA — Wed, 14 Jun 2023 09:10:57 GMT

←Older revision		Revision as of 09:10, 14 June 2023
Line 1:		Line 1:

	==Eurocin solution structure==		==Eurocin solution structure==
-	<StructureSection load='2lt8' size='340' side='right'caption='[[2lt8~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2lt8' size='340' side='right'caption='[[2lt8]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Aspam Aspam~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_amstelodami Aspergillus amstelodami]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [https://pdbe.org/2lt8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [https://www.ebi.ac.uk/pdbsum/2lt8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lt8 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [https://pdbe.org/2lt8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [https://www.ebi.ac.uk/pdbsum/2lt8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lt8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DEFEU_ASPAM DEFEU_ASPAM]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Aspam~~]]	+	[[Category: Aspergillus amstelodami]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hansen~~, F T~~]]	+	[[Category: Hansen FT]]
-	[[Category: Knudsen~~, D H~~]]	+	[[Category: Knudsen DH]]
-	[[Category: Kristensen, H]]	+	[[Category: Kristensen H]]
-	[[Category: Lynggaard, C]]	+	[[Category: Lynggaard C]]
-	[[Category: Neve, S]]	+	[[Category: Neve S]]
-	[[Category: Noergaard~~, K D~~]]	+	[[Category: Noergaard KD]]
-	[[Category: Oeemig~~, J S~~]]	+	[[Category: Oeemig JS]]
-	[[Category: Otzen~~, D E~~]]	+	[[Category: Otzen DE]]
-	[[Category: Sahl, H]]	+	[[Category: Sahl H]]
-	[[Category: Schneider, T]]	+	[[Category: Schneider T]]
-	[[Category: Vad~~, B S~~]]	+	[[Category: Vad BS]]
-	[[Category: Wimmer, R]]	+	[[Category: Wimmer R]]
-	~~[[Category: A/b-fold]]~~	+
-	~~[[Category: Antimicrobial protein]]~~	+
-	~~[[Category: Cysteine stabilised~~]]	+

OCA at 07:54, 9 February 2022

OCA — Wed, 09 Feb 2022 07:54:22 GMT

←Older revision		Revision as of 07:54, 9 February 2022
Line 3:		Line 3:
	<StructureSection load='2lt8' size='340' side='right'caption='[[2lt8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lt8' size='340' side='right'caption='[[2lt8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Aspam Aspam]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspam Aspam]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [~~http~~://pdbe.org/2lt8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lt8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lt8 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [https://pdbe.org/2lt8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [https://www.ebi.ac.uk/pdbsum/2lt8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lt8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:08, 6 May 2020

OCA — Wed, 06 May 2020 07:08:10 GMT

←Older revision		Revision as of 07:08, 6 May 2020
Line 1:		Line 1:

	==Eurocin solution structure==		==Eurocin solution structure==
-	<StructureSection load='2lt8' size='340' side='right' caption='[[2lt8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2lt8' size='340' side='right'caption='[[2lt8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspam Aspam]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspam Aspam]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [http://pdbe.org/2lt8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [http://www.ebi.ac.uk/pdbsum/2lt8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lt8 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [http://pdbe.org/2lt8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [http://www.ebi.ac.uk/pdbsum/2lt8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lt8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Aspam]]		[[Category: Aspam]]
		+	[[Category: Large Structures]]
	[[Category: Hansen, F T]]		[[Category: Hansen, F T]]
	[[Category: Knudsen, D H]]		[[Category: Knudsen, D H]]

OCA at 19:19, 1 August 2018

OCA — Wed, 01 Aug 2018 19:19:34 GMT

←Older revision		Revision as of 19:19, 1 August 2018
Line 1:		Line 1:
		+
	==Eurocin solution structure==		==Eurocin solution structure==
	<StructureSection load='2lt8' size='340' side='right' caption='[[2lt8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lt8' size='340' side='right' caption='[[2lt8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspam Aspam]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspam Aspam]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [http://pdbe.org/2lt8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [http://www.ebi.ac.uk/pdbsum/2lt8 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [http://pdbe.org/2lt8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [http://www.ebi.ac.uk/pdbsum/2lt8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lt8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:05, 10 September 2015

OCA — Thu, 10 Sep 2015 23:05:14 GMT

←Older revision		Revision as of 23:05, 10 September 2015
Line 1:		Line 1:
-	[[~~Image~~:2lt8.~~png\|left\|200px~~]]	+	==Eurocin solution structure==
		+	<StructureSection load='2lt8' size='340' side='right' caption='[[2lt8]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2lt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspam Aspam]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LT8 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lt8 OCA], [http://pdbe.org/2lt8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lt8 RCSB], [http://www.ebi.ac.uk/pdbsum/2lt8 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Antimicrobial peptides are a new class of antibiotics that are promising for pharmaceutical applications, since they have retained efficacy throughout evolution. One class of antimicrobial peptides are the defensins, that have been found in different species. Here we describe a new fungal defensin, eurocin. Eurocin acts against a range of gram-positive human pathogens, but not against gram-negative bacteria. Eurocin consists of 42 amino acids, forming a cysteine-stabilized alpha/beta fold. Thermal denaturation data point shows the disulphide bridges being responsible for the stability of the fold. Eurocin does not form pores in cell membranes at physiologically relevant concentrations, it does, however, lead to limited leakage of a fluorophore from small unilamellar vesicles. Eurocin interacts with detergent micelles, and it inhibits the synthesis of cell walls by binding equimolarly to the cell wall precursor lipid II.

-	~~{{STRUCTURE_2lt8\| PDB=2lt8 \| SCENE= }}~~	+	Eurocin, a new fungal defensin: structure, lipid binding and its mode of action.,Oeemig JS, Lynggaard C, Knudsen DH, Hansen FT, Noergaard KD, Schneider T, Vad BS, Sandvang D, Nielsen LA, Neve S, Kristensen HH, Sahl HG, Otzen DE, Wimmer R J Biol Chem. 2012 Oct 23. PMID:23093408<ref>PMID:23093408</ref>

-	===~~Eurocin solution structure~~===	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23093408}}~~	+	<div class="pdbe-citations 2lt8" style="background-color:#fffaf0;"></div>
-		+	== References ==
-	~~==About this Structure==~~	+	<references/>
-	~~[[2lt8]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Eurotium_amstelodami Eurotium amstelodami]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA].~~	+	__TOC__
-	[[Category: ~~Eurotium amstelodami~~]]	+	</StructureSection>
-	[[Category: Hansen, F T.]]	+	[[Category: Aspam]]
-	[[Category: Knudsen, D H.]]	+	[[Category: Hansen, F T]]
-	[[Category: Kristensen, H.]]	+	[[Category: Knudsen, D H]]
-	[[Category: Lynggaard, C.]]	+	[[Category: Kristensen, H]]
-	[[Category: Neve, S.]]	+	[[Category: Lynggaard, C]]
-	[[Category: Noergaard, K D.]]	+	[[Category: Neve, S]]
-	[[Category: Oeemig, J S.]]	+	[[Category: Noergaard, K D]]
-	[[Category: Otzen, D E.]]	+	[[Category: Oeemig, J S]]
-	[[Category: Sahl, H.]]	+	[[Category: Otzen, D E]]
-	[[Category: Schneider, T.]]	+	[[Category: Sahl, H]]
-	[[Category: Vad, B S.]]	+	[[Category: Schneider, T]]
-	[[Category: Wimmer, R.]]	+	[[Category: Vad, B S]]
		+	[[Category: Wimmer, R]]
	[[Category: A/b-fold]]		[[Category: A/b-fold]]
	[[Category: Antimicrobial protein]]		[[Category: Antimicrobial protein]]
	[[Category: Cysteine stabilised]]		[[Category: Cysteine stabilised]]

OCA at 07:04, 2 January 2013

OCA — Wed, 02 Jan 2013 07:04:35 GMT

←Older revision		Revision as of 07:04, 2 January 2013
Line 5:		Line 5:
	===Eurocin solution structure===		===Eurocin solution structure===

		+	{{ABSTRACT_PUBMED_23093408}}

	==About this Structure==		==About this Structure==

OCA at 13:44, 8 November 2012

OCA — Thu, 08 Nov 2012 13:44:43 GMT

←Older revision		Revision as of 13:44, 8 November 2012
Line 1:		Line 1:
-	[[Image:2lt8.~~jpg~~\|left\|200px]]	+	[[Image:2lt8.png\|left\|200px]]

	{{STRUCTURE_2lt8\| PDB=2lt8 \| SCENE= }}		{{STRUCTURE_2lt8\| PDB=2lt8 \| SCENE= }}

OCA at 09:12, 31 October 2012

OCA — Wed, 31 Oct 2012 09:12:55 GMT

←Older revision		Revision as of 09:12, 31 October 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:2lt8.jpg\|left\|200px]]

-	~~The entry~~ 2lt8 ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_2lt8\| PDB=2lt8 \| SCENE= }}

-	~~Authors: Oeemig, J.S., Lynggaard, C., Knudsen, D.H., Hansen, F.T., Noergaard, K.D., Schneider, T., Vad, B.S., Neve, S., Kristensen, H., Sahl, H., Otzen, D.E., Wimmer, R.~~	+	===Eurocin solution structure===

-	~~Description: Eurocin solution~~ structure	+
		+	==About this Structure==
		+	[[2lt8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Eurotium_amstelodami Eurotium amstelodami]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LT8 OCA].
		+	[[Category: Eurotium amstelodami]]
		+	[[Category: Hansen, F T.]]
		+	[[Category: Knudsen, D H.]]
		+	[[Category: Kristensen, H.]]
		+	[[Category: Lynggaard, C.]]
		+	[[Category: Neve, S.]]
		+	[[Category: Noergaard, K D.]]
		+	[[Category: Oeemig, J S.]]
		+	[[Category: Otzen, D E.]]
		+	[[Category: Sahl, H.]]
		+	[[Category: Schneider, T.]]
		+	[[Category: Vad, B S.]]
		+	[[Category: Wimmer, R.]]
		+	[[Category: A/b-fold]]
		+	[[Category: Antimicrobial protein]]
		+	[[Category: Cysteine stabilised]]

OCA at 05:06, 27 June 2012

OCA — Wed, 27 Jun 2012 05:06:58 GMT

←Older revision		Revision as of 05:06, 27 June 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2lt8 is ON HOLD	+	The entry 2lt8 is ON HOLD until Paper Publication

	Authors: Oeemig, J.S., Lynggaard, C., Knudsen, D.H., Hansen, F.T., Noergaard, K.D., Schneider, T., Vad, B.S., Neve, S., Kristensen, H., Sahl, H., Otzen, D.E., Wimmer, R.		Authors: Oeemig, J.S., Lynggaard, C., Knudsen, D.H., Hansen, F.T., Noergaard, K.D., Schneider, T., Vad, B.S., Neve, S., Kristensen, H., Sahl, H., Otzen, D.E., Wimmer, R.

	Description: Eurocin solution structure		Description: Eurocin solution structure

OCA: Protected "2lt8" [edit=sysop:move=sysop]

OCA — Wed, 23 May 2012 05:24:30 GMT

Protected "2lt8" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:24, 23 May 2012