2lw1 - Revision history

OCA at 05:53, 15 May 2024

OCA — Wed, 15 May 2024 05:53:53 GMT

←Older revision		Revision as of 05:53, 15 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [https://pdbe.org/2lw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw1 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [https://pdbe.org/2lw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 13:13, 22 February 2023

OCA — Wed, 22 Feb 2023 13:13:50 GMT

←Older revision		Revision as of 13:13, 22 February 2023
Line 1:		Line 1:

	==The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif==		==The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif==
-	<StructureSection load='2lw1' size='340' side='right'caption='[[2lw1~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2lw1' size='340' side='right'caption='[[2lw1]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [https://pdbe.org/2lw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw1 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [https://pdbe.org/2lw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw1 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/UUP_ECOLI UUP_ECOLI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Carlier, L]]	+	[[Category: Burgos Zepeda MY]]
-	[[Category: Dassa, E]]	+	[[Category: Carlier L]]
-	[[Category: Haase~~, A S~~]]	+	[[Category: Dassa E]]
-	[[Category: Lequin, O]]	+	[[Category: Haase AS]]
-	~~[[Category: Zepeda, M Y.Burgos]]~~	+	[[Category: Lequin O]]
-	~~[[Category: Abc reg subfamily]]~~	+
-	~~[[Category: Dna binding protein~~]]	+

OCA at 10:54, 19 May 2021

OCA — Wed, 19 May 2021 10:54:46 GMT

←Older revision		Revision as of 10:54, 19 May 2021
Line 1:		Line 1:

	==The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif==		==The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif==
-	<StructureSection load='2lw1' size='340' side='right' caption='[[2lw1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2lw1' size='340' side='right'caption='[[2lw1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [~~http~~://pdbe.org/2lw1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lw1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [https://pdbe.org/2lw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Carlier, L]]		[[Category: Carlier, L]]
	[[Category: Dassa, E]]		[[Category: Dassa, E]]

OCA at 22:45, 9 August 2018

OCA — Thu, 09 Aug 2018 22:45:16 GMT

←Older revision		Revision as of 22:45, 9 August 2018
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [http://pdbe.org/2lw1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2lw1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [http://pdbe.org/2lw1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2lw1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:27, 10 May 2016

OCA — Tue, 10 May 2016 16:27:41 GMT

←Older revision		Revision as of 16:27, 10 May 2016
Line 1:		Line 1:
		+
	==The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif==		==The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif==
	<StructureSection load='2lw1' size='340' side='right' caption='[[2lw1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lw1' size='340' side='right' caption='[[2lw1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>

OCA at 04:03, 10 September 2015

OCA — Thu, 10 Sep 2015 04:03:01 GMT

←Older revision		Revision as of 04:03, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2lw1' size='340' side='right' caption='[[2lw1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lw1' size='340' side='right' caption='[[2lw1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli_k-12 Escherichia coli k-12~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ~~Escherichia coli K-12~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2lw1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [http://pdbe.org/2lw1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2lw1 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2lw1" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli k-12~~]]	+	[[Category: Ecoli]]
	[[Category: Carlier, L]]		[[Category: Carlier, L]]
	[[Category: Dassa, E]]		[[Category: Dassa, E]]

OCA at 13:33, 19 January 2015

OCA — Mon, 19 Jan 2015 13:33:33 GMT

←Older revision		Revision as of 13:33, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2lw1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2lw1 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
-	[[Category: Carlier, L.]]	+	[[Category: Carlier, L]]
-	[[Category: Dassa, E.]]	+	[[Category: Dassa, E]]
-	[[Category: Haase, A S.]]	+	[[Category: Haase, A S]]
-	[[Category: Lequin, O.]]	+	[[Category: Lequin, O]]
-	[[Category: Zepeda, M Y.Burgos.]]	+	[[Category: Zepeda, M Y.Burgos]]
	[[Category: Abc reg subfamily]]		[[Category: Abc reg subfamily]]
	[[Category: Dna binding protein]]		[[Category: Dna binding protein]]

OCA at 02:18, 29 September 2014

OCA — Mon, 29 Sep 2014 02:18:05 GMT

←Older revision		Revision as of 02:18, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~2lw1.~~png~~\|~~left\|200px~~]]	+	==The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif==
		+	<StructureSection load='2lw1' size='340' side='right' caption='[[2lw1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LW1 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">uup, ycbH, ycbI, b0949, JW0932 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 Escherichia coli K-12])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lw1 RCSB], [http://www.ebi.ac.uk/pdbsum/2lw1 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The bacterial Uup protein belongs to the REG subfamily of soluble ATP-binding cassette (ABC) ATPases, and is implicated in precise excision of transposons. In Escherichia coli, the uup gene encodes a 72kDa polypeptide that comprises two ABC domains, separated by a linker region, and a 12kDa C-terminal domain (CTD). Uup binds double-stranded DNA with no sequence specificity, and we previously demonstrated that the CTD domain is a crucial region that participates in DNA-binding activity. We report herein the NMR structure of Uup CTD, consisting of an intramolecular antiparallel two-stranded coiled coil motif. Structural comparison with analogous coiled coil domains reveals that Uup CTD contains an atypical 3(10)-helix in the alpha-hairpin region that contributes to the hydrophobic core. Using NMR titration experiments, we identified residues of the CTD domain involved in the binding to double-stranded DNA. These residues are located on two opposite surfaces at the base of the coiled coil, formed by the N- and C-terminal extremities, where a strictly conserved proline residue induces an overwinding of the coiled coil. Finally, preliminary analysis of NMR spectra recorded on distinct Uup constructs precludes a fully flexible positioning of the CTD domain in full-length Uup. These structural data are the first reported for a non-ATPase domain within ABC REG subfamily.

-	~~{{STRUCTURE_2lw1\| PDB=2lw1 \| SCENE= }}~~	+	The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif.,Carlier L, Sander Haase A, Burgos Zepeda MY, Dassa E, Lequin O J Struct Biol. 2012 Sep 17. pii: S1047-8477(12)00247-X. doi:, 10.1016/j.jsb.2012.09.005. PMID:22995754<ref>PMID:22995754</ref>

-	~~===The C-terminal domain~~ of the ~~Uup protein is a DNA-binding coiled coil motif===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22995754}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[2lw1]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA].~~	+	</StructureSection>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
	[[Category: Carlier, L.]]		[[Category: Carlier, L.]]

OCA at 14:42, 28 November 2012

OCA — Wed, 28 Nov 2012 14:42:58 GMT

←Older revision		Revision as of 14:42, 28 November 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli~~ Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA].	+	[[2lw1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW1 OCA].
-	[[Category: Escherichia coli]]	+	[[Category: Escherichia coli k-12]]
	[[Category: Carlier, L.]]		[[Category: Carlier, L.]]
	[[Category: Dassa, E.]]		[[Category: Dassa, E.]]

OCA at 06:09, 3 October 2012

OCA — Wed, 03 Oct 2012 06:09:47 GMT

←Older revision		Revision as of 06:09, 3 October 2012
Line 1:		Line 1:
-	[[Image:2lw1.~~jpg~~\|left\|200px]]	+	[[Image:2lw1.png\|left\|200px]]

	{{STRUCTURE_2lw1\| PDB=2lw1 \| SCENE= }}		{{STRUCTURE_2lw1\| PDB=2lw1 \| SCENE= }}
Line 5:		Line 5:
	===The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif===		===The C-terminal domain of the Uup protein is a DNA-binding coiled coil motif===

-	{{~~ABSTRACT_PUBMED_22287065~~}}	+	{{ABSTRACT_PUBMED_22995754}}

	==About this Structure==		==About this Structure==