2lwv - Revision history

OCA at 09:19, 14 June 2023

OCA — Wed, 14 Jun 2023 09:19:56 GMT

←Older revision		Revision as of 09:19, 14 June 2023
Line 1:		Line 1:

	==NMR solution structure of PawS Derived Peptide 6 (PDP-6)==		==NMR solution structure of PawS Derived Peptide 6 (PDP-6)==
-	<StructureSection load='2lwv' size='340' side='right'caption='[[2lwv~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2lwv' size='340' side='right'caption='[[2lwv]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LWV FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LWV FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</div></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [https://pdbe.org/2lwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [https://www.ebi.ac.uk/pdbsum/2lwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwv ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [https://pdbe.org/2lwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [https://www.ebi.ac.uk/pdbsum/2lwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwv ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 21:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Elliott~~, A G~~]]	+	[[Category: Elliott AG]]
-	[[Category: Mylne~~, J S~~]]	+	[[Category: Mylne JS]]
-	[[Category: Rosengren, K]]	+	[[Category: Rosengren K]]
-	~~[[Category: Cyclic peptide]]~~	+
-	~~[[Category: Paws derived]]~~	+
-	~~[[Category: Plant peptide]]~~	+
-	~~[[Category: Plant protein~~]]	+

OCA at 11:30, 16 February 2022

OCA — Wed, 16 Feb 2022 11:30:23 GMT

←Older revision		Revision as of 11:30, 16 February 2022
Line 3:		Line 3:
	<StructureSection load='2lwv' size='340' side='right'caption='[[2lwv]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lwv' size='340' side='right'caption='[[2lwv]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LWV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LWV FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [~~http~~://pdbe.org/2lwv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lwv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [https://pdbe.org/2lwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [https://www.ebi.ac.uk/pdbsum/2lwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwv ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:16, 13 May 2020

OCA — Wed, 13 May 2020 06:16:09 GMT

←Older revision		Revision as of 06:16, 13 May 2020
Line 1:		Line 1:

	==NMR solution structure of PawS Derived Peptide 6 (PDP-6)==		==NMR solution structure of PawS Derived Peptide 6 (PDP-6)==
-	<StructureSection load='2lwv' size='340' side='right' caption='[[2lwv]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2lwv' size='340' side='right'caption='[[2lwv]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LWV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LWV FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://pdbe.org/2lwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://pdbe.org/2lwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwv ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Elliott, A G]]		[[Category: Elliott, A G]]
	[[Category: Mylne, J S]]		[[Category: Mylne, J S]]

OCA at 23:05, 9 August 2018

OCA — Thu, 09 Aug 2018 23:05:25 GMT

←Older revision		Revision as of 23:05, 9 August 2018
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LWV FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LWV FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://pdbe.org/2lwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://pdbe.org/2lwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lwv ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:23, 1 June 2016

OCA — Wed, 01 Jun 2016 08:23:04 GMT

←Older revision		Revision as of 08:23, 1 June 2016
Line 1:		Line 1:
		+
	==NMR solution structure of PawS Derived Peptide 6 (PDP-6)==		==NMR solution structure of PawS Derived Peptide 6 (PDP-6)==
	<StructureSection load='2lwv' size='340' side='right' caption='[[2lwv]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lwv' size='340' side='right' caption='[[2lwv]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 6:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://pdbe.org/2lwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://pdbe.org/2lwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The de novo evolution of proteins is now considered a frequented route for biological innovation, but the genetic and biochemical processes that lead to each newly created protein are often poorly documented. The common sunflower (Helianthus annuus) contains the unusual gene PawS1 (Preproalbumin with SFTI-1) that encodes a precursor for seed storage albumin; however, in a region usually discarded during albumin maturation, its sequence is matured into SFTI-1, a protease-inhibiting cyclic peptide with a motif homologous to unrelated inhibitors from legumes, cereals, and frogs. To understand how PawS1 acquired this additional peptide with novel biochemical functionality, we cloned PawS1 genes and showed that this dual destiny is over 18 million years old. This new family of mostly backbone-cyclic peptides is structurally diverse, but the protease-inhibitory motif was restricted to peptides from sunflower and close relatives from its subtribe. We describe a widely distributed, potential evolutionary intermediate PawS-Like1 (PawL1), which is matured into storage albumin, but makes no stable peptide despite possessing residues essential for processing and cyclization from within PawS1. Using sequences we cloned, we retrodict the likely stepwise creation of PawS1's additional destiny within a simple albumin precursor. We propose that relaxed selection enabled SFTI-1 to evolve its inhibitor function by converging upon a successful sequence and structure.
		+
		+	Evolutionary origins of a bioactive peptide buried within Preproalbumin.,Elliott AG, Delay C, Liu H, Phua Z, Rosengren KJ, Benfield AH, Panero JL, Colgrave ML, Jayasena AS, Dunse KM, Anderson MA, Schilling EE, Ortiz-Barrientos D, Craik DJ, Mylne JS Plant Cell. 2014 Mar;26(3):981-95. doi: 10.1105/tpc.114.123620. Epub 2014 Mar 28. PMID:24681618<ref>PMID:24681618</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 2lwv" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:26, 10 September 2015

OCA — Thu, 10 Sep 2015 14:26:54 GMT

←Older revision		Revision as of 14:26, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LWV FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LWV FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://pdbe.org/2lwv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 12:37, 18 December 2014

OCA — Thu, 18 Dec 2014 12:37:06 GMT

←Older revision		Revision as of 12:37, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2lwv\| PDB=2lwv \| SCENE= }}~~	+	==NMR solution structure of PawS Derived Peptide 6 (PDP-6)==
-	===NMR solution structure of PawS Derived Peptide 6 (PDP-6)===	+	<StructureSection load='2lwv' size='340' side='right' caption='[[2lwv]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LWV FirstGlance]. <br>
-	[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA].	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lwq\|2lwq]], [[2lws\|2lws]], [[2lwt\|2lwt]], [[2lwu\|2lwu]]</td></tr>
-	[[Category: Elliott, A G.]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lwv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lwv RCSB], [http://www.ebi.ac.uk/pdbsum/2lwv PDBsum]</span></td></tr>
-	[[Category: Mylne, J S.]]	+	</table>
-	[[Category: Rosengren, K.]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Elliott, A G]]
		+	[[Category: Mylne, J S]]
		+	[[Category: Rosengren, K]]
	[[Category: Cyclic peptide]]		[[Category: Cyclic peptide]]
	[[Category: Paws derived]]		[[Category: Paws derived]]
	[[Category: Plant peptide]]		[[Category: Plant peptide]]
	[[Category: Plant protein]]		[[Category: Plant protein]]

OCA at 08:29, 21 August 2013

OCA — Wed, 21 Aug 2013 08:29:49 GMT

←Older revision		Revision as of 08:29, 21 August 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_2lwv\| PDB=2lwv \| SCENE= }}
		+	===NMR solution structure of PawS Derived Peptide 6 (PDP-6)===

-	~~The entry~~ 2lwv is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[2lwv]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LWV OCA].
-	~~Authors~~: Elliott, A.G., Mylne, J.S., Rosengren, K.	+	[[Category: Elliott, A G.]]
-		+	[[Category: Mylne, J S.]]
-	~~Description~~: ~~NMR solution structure of PawS Derived Peptide 6 (PDP-6)~~	+	[[Category: Rosengren, K.]]
		+	[[Category: Cyclic peptide]]
		+	[[Category: Paws derived]]
		+	[[Category: Plant peptide]]
		+	[[Category: Plant protein]]

OCA at 04:29, 29 August 2012

OCA — Wed, 29 Aug 2012 04:29:01 GMT

←Older revision		Revision as of 04:29, 29 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2lwv is ON HOLD	+	The entry 2lwv is ON HOLD until Paper Publication

	Authors: Elliott, A.G., Mylne, J.S., Rosengren, K.		Authors: Elliott, A.G., Mylne, J.S., Rosengren, K.

	Description: NMR solution structure of PawS Derived Peptide 6 (PDP-6)		Description: NMR solution structure of PawS Derived Peptide 6 (PDP-6)

OCA: Protected "2lwv" [edit=sysop:move=sysop]

OCA — Wed, 15 Aug 2012 05:05:07 GMT

Protected "2lwv" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:05, 15 August 2012