2m5u - Revision history

OCA at 06:00, 15 May 2024

OCA — Wed, 15 May 2024 06:00:36 GMT

←Older revision		Revision as of 06:00, 15 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5U FirstGlance]. <br>		<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [https://pdbe.org/2m5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [https://www.ebi.ac.uk/pdbsum/2m5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5u ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [https://pdbe.org/2m5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [https://www.ebi.ac.uk/pdbsum/2m5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5u ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:28, 14 June 2023

OCA — Wed, 14 Jun 2023 09:28:41 GMT

←Older revision		Revision as of 09:28, 14 June 2023
Line 1:		Line 1:

	==NMR structure of the P4 hairpin of the CPEB3 ribozyme==		==NMR structure of the P4 hairpin of the CPEB3 ribozyme==
-	<StructureSection load='2m5u' size='340' side='right'caption='[[2m5u~~]], [[NMR_Ensembles_of_Models \| 15 NMR models~~]]' scene=''>	+	<StructureSection load='2m5u' size='340' side='right'caption='[[2m5u]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5U FirstGlance]. <br>		<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Rowinska-Zyrek, M]]	+	[[Category: Rowinska-Zyrek M]]
-	[[Category: Sigel~~, R K.O~~]]	+	[[Category: Sigel RKO]]
-	[[Category: Skilandat, M]]	+	[[Category: Skilandat M]]
-	~~[[Category: Cpeb3]]~~	+
-	~~[[Category: Hairpin]]~~	+
-	~~[[Category: Ribozyme]]~~	+
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Uggu tetraloop~~]]	+

OCA at 11:32, 16 February 2022

OCA — Wed, 16 Feb 2022 11:32:46 GMT

←Older revision		Revision as of 11:32, 16 February 2022
Line 3:		Line 3:
	<StructureSection load='2m5u' size='340' side='right'caption='[[2m5u]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='2m5u' size='340' side='right'caption='[[2m5u]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2M5U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [~~http~~://pdbe.org/2m5u PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2m5u PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5u ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [https://pdbe.org/2m5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [https://www.ebi.ac.uk/pdbsum/2m5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5u ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:19, 13 May 2020

OCA — Wed, 13 May 2020 06:19:15 GMT

←Older revision		Revision as of 06:19, 13 May 2020
Line 1:		Line 1:

	==NMR structure of the P4 hairpin of the CPEB3 ribozyme==		==NMR structure of the P4 hairpin of the CPEB3 ribozyme==
-	<StructureSection load='2m5u' size='340' side='right' caption='[[2m5u]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>	+	<StructureSection load='2m5u' size='340' side='right'caption='[[2m5u]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2M5U FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://pdbe.org/2m5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5u ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://pdbe.org/2m5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5u ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Rowinska-Zyrek, M]]		[[Category: Rowinska-Zyrek, M]]
	[[Category: Sigel, R K.O]]		[[Category: Sigel, R K.O]]

OCA at 22:41, 9 August 2018

OCA — Thu, 09 Aug 2018 22:41:18 GMT

←Older revision		Revision as of 22:41, 9 August 2018
Line 1:		Line 1:
		+
	==NMR structure of the P4 hairpin of the CPEB3 ribozyme==		==NMR structure of the P4 hairpin of the CPEB3 ribozyme==
	<StructureSection load='2m5u' size='340' side='right' caption='[[2m5u]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='2m5u' size='340' side='right' caption='[[2m5u]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5U FirstGlance]. <br>		<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://pdbe.org/2m5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://pdbe.org/2m5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2m5u ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:07, 11 September 2015

OCA — Fri, 11 Sep 2015 15:07:35 GMT

←Older revision		Revision as of 15:07, 11 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5U FirstGlance]. <br>		<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://pdbe.org/2m5u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 13:		Line 13:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2m5u" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:23, 5 January 2015

OCA — Mon, 05 Jan 2015 14:23:15 GMT

←Older revision		Revision as of 14:23, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5U FirstGlance]. <br>		<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Rowinska-Zyrek, M.]]	+	[[Category: Rowinska-Zyrek, M]]
-	[[Category: Sigel, R K.O.]]	+	[[Category: Sigel, R K.O]]
-	[[Category: Skilandat, M.]]	+	[[Category: Skilandat, M]]
	[[Category: Cpeb3]]		[[Category: Cpeb3]]
	[[Category: Hairpin]]		[[Category: Hairpin]]

OCA at 13:48, 20 August 2014

OCA — Wed, 20 Aug 2014 13:48:55 GMT

←Older revision		Revision as of 13:48, 20 August 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_2m5u\| PDB~~=2m5u \| ~~SCENE~~= }}	+	==NMR structure of the P4 hairpin of the CPEB3 ribozyme==
-	===NMR structure of the P4 hairpin of the CPEB3 ribozyme~~===~~	+	<StructureSection load='2m5u' size='340' side='right' caption='[[2m5u]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
-	~~{{ABSTRACT_PUBMED_24652468}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M5U FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m5u RCSB], [http://www.ebi.ac.uk/pdbsum/2m5u PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Three ribozymes are known to occur in humans, the CPEB3 ribozyme, the CoTC ribozyme, and the hammerhead ribozyme. Here, we present the NMR solution structure of a well-conserved motif within the CPEB3 ribozyme, the P4 domain. In addition, we discuss the binding sites and impact of Mg2+ and [Co(NH3)6]3+, a spectroscopic probe for [Mg(H2O)6]2+, on the structure. The well-defined P4 region is a hairpin closed with a UGGU tetraloop that shows a distinct electrostatic surface potential and a characteristic, strongly curved backbone trajectory. The P4 hairpin contains two specific Mg2+ binding sites: one outer-sphere binding site close to the proposed CPEB3 ribozyme active site with potential relevance for maintaining a compact fold of the ribozyme core, and one inner-sphere binding site, probably stabilizing the tetraloop structure. The structure of the tetraloop resembles an RNase III recognition structure, as previously described for an AGUU tetraloop. The detailed knowledge of the P4 domain and its metal ion binding preferences thus brings us closer to understanding the importance of Mg2+ binding for the CPEB3 ribozyme's fold and function in the cell.

-	~~==About this Structure==~~	+	Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain.,Skilandat M, Rowinska-Zyrek M, Sigel RK J Biol Inorg Chem. 2014 Mar 21. PMID:24652468<ref>PMID:24652468</ref>
-	~~[[2m5u]] is a 1 chain~~ structure. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=2M5U OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024652468</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Rowinska-Zyrek, M.]]		[[Category: Rowinska-Zyrek, M.]]
	[[Category: Sigel, R K.O.]]		[[Category: Sigel, R K.O.]]

OCA at 09:25, 2 April 2014

OCA — Wed, 02 Apr 2014 09:25:55 GMT

←Older revision		Revision as of 09:25, 2 April 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_2m5u\| PDB=2m5u \| SCENE= }}
		+	===NMR structure of the P4 hairpin of the CPEB3 ribozyme===
		+	{{ABSTRACT_PUBMED_24652468}}

-	~~The entry~~ 2m5u is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[2m5u]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M5U OCA].

-	~~Authors~~: ~~Skilandat, M.,~~ Rowinska-Zyrek, M., Sigel, R.K.O.	+	==Reference==
-		+	<ref group="xtra">PMID:024652468</ref><references group="xtra"/><references/>
-	~~Description~~: ~~NMR structure of the P4 hairpin of the CPEB3 ribozyme~~	+	[[Category: Rowinska-Zyrek, M.]]
		+	[[Category: Sigel, R K.O.]]
		+	[[Category: Skilandat, M.]]
		+	[[Category: Cpeb3]]
		+	[[Category: Hairpin]]
		+	[[Category: Ribozyme]]
		+	[[Category: Rna]]
		+	[[Category: Uggu tetraloop]]

OCA at 06:51, 2 May 2013

OCA — Thu, 02 May 2013 06:51:10 GMT

←Older revision		Revision as of 06:51, 2 May 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2m5u is ON HOLD	+	The entry 2m5u is ON HOLD until Paper Publication

	Authors: Skilandat, M., Rowinska-Zyrek, M., Sigel, R.K.O.		Authors: Skilandat, M., Rowinska-Zyrek, M., Sigel, R.K.O.

	Description: NMR structure of the P4 hairpin of the CPEB3 ribozyme		Description: NMR structure of the P4 hairpin of the CPEB3 ribozyme