2mk3 - Revision history

OCA at 07:00, 1 May 2024

OCA — Wed, 01 May 2024 07:00:43 GMT

←Older revision		Revision as of 07:00, 1 May 2024
Line 9:		Line 9:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/D0VWW0_9HIV1 D0VWW0_9HIV1]		[https://www.uniprot.org/uniprot/D0VWW0_9HIV1 D0VWW0_9HIV1]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The envelope glycoprotein gp41 mediates the process of membrane fusion that enables entry of the HIV-1 virus into the host cell. The actual fusion process involves a switch from a homotrimeric prehairpin intermediate conformation, consisting of parallel coiled-coil helices, to a postfusion state where the ectodomains are arranged as a trimer of helical hairpins, adopting a six-helix bundle (6HB) state. Here, we show by solution NMR spectroscopy that a water-soluble 6HB gp41 ectodomain binds to zwitterionic detergents that contain phosphocholine or phosphatidylcholine head groups and phospholipid vesicles that mimic T-cell membrane composition. Binding results in the dissociation of the 6HB and the formation of a monomeric state, where its two alpha-helices, N-terminal heptad repeat (NHR) and C-terminal heptad repeat (CHR), become embedded in the lipid-water interface of the virus and host cell. The atomic structure of the gp41 ectodomain monomer, based on NOE distance restraints and residual dipolar couplings, shows that the NHR and CHR helices remain mostly intact, but they completely lose interhelical contacts. The high affinity of the ectodomain helices for phospholipid surfaces suggests that unzippering of the prehairpin intermediate leads to a state where the NHR and CHR helices become embedded in the host cell and viral membranes, respectively, thereby providing a physical force for bringing these membranes into close juxtaposition before actual fusion.
-
-	Dissociation of the trimeric gp41 ectodomain at the lipid-water interface suggests an active role in HIV-1 Env-mediated membrane fusion.,Roche J, Louis JM, Grishaev A, Ying J, Bax A Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3425-30. doi:, 10.1073/pnas.1401397111. Epub 2014 Feb 18. PMID:24550514<ref>PMID:24550514</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 2mk3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Gp41 3D Structures\|Gp41 3D Structures]]		*[[Gp41 3D Structures\|Gp41 3D Structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:56, 22 November 2023

OCA — Wed, 22 Nov 2023 11:56:55 GMT

←Older revision		Revision as of 11:56, 22 November 2023
Line 1:		Line 1:

	==Solution NMR structure of gp41 ectodomain monomer on a DPC micelle==		==Solution NMR structure of gp41 ectodomain monomer on a DPC micelle==
-	<StructureSection load='2mk3' size='340' side='right'caption='[[2mk3~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2mk3' size='340' side='right'caption='[[2mk3]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~9hiv1 9hiv1~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [https://pdbe.org/2mk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [https://www.ebi.ac.uk/pdbsum/2mk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk3 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [https://pdbe.org/2mk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [https://www.ebi.ac.uk/pdbsum/2mk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/D0VWW0_9HIV1 D0VWW0_9HIV1]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 2mk3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2mk3" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Gp41 3D Structures\|Gp41 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human immunodeficiency virus 1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bax, A]]	+	[[Category: Bax A]]
-	[[Category: Grishaev, A]]	+	[[Category: Grishaev A]]
-	[[Category: Louis~~, J M~~]]	+	[[Category: Louis JM]]
-	[[Category: Roche, J]]	+	[[Category: Roche J]]
-	[[Category: Ying, J]]	+	[[Category: Ying J]]
-	~~[[Category: Core]]~~	+
-	~~[[Category: Gp41 ectodomain]]~~	+
-	~~[[Category: Hiv-1 env]]~~	+
-	~~[[Category: Immune system]]~~	+
-	~~[[Category: Membrane fusion]]~~	+
-	~~[[Category: Pre-hairpin~~]]	+

OCA at 11:36, 16 February 2022

OCA — Wed, 16 Feb 2022 11:36:47 GMT

←Older revision		Revision as of 11:36, 16 February 2022
Line 3:		Line 3:
	<StructureSection load='2mk3' size='340' side='right'caption='[[2mk3]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2mk3' size='340' side='right'caption='[[2mk3]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [~~http~~://pdbe.org/2mk3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2mk3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk3 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [https://pdbe.org/2mk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [https://www.ebi.ac.uk/pdbsum/2mk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk3 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:25, 13 May 2020

OCA — Wed, 13 May 2020 06:25:02 GMT

←Older revision		Revision as of 06:25, 13 May 2020
Line 1:		Line 1:

	==Solution NMR structure of gp41 ectodomain monomer on a DPC micelle==		==Solution NMR structure of gp41 ectodomain monomer on a DPC micelle==
-	<StructureSection load='2mk3' size='340' side='right' caption='[[2mk3]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2mk3' size='340' side='right'caption='[[2mk3]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [http://pdbe.org/2mk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk3 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [http://pdbe.org/2mk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk3 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bax, A]]		[[Category: Bax, A]]
	[[Category: Grishaev, A]]		[[Category: Grishaev, A]]

OCA at 22:43, 9 August 2018

OCA — Thu, 09 Aug 2018 22:43:52 GMT

←Older revision		Revision as of 22:43, 9 August 2018
Line 1:		Line 1:
		+
	==Solution NMR structure of gp41 ectodomain monomer on a DPC micelle==		==Solution NMR structure of gp41 ectodomain monomer on a DPC micelle==
	<StructureSection load='2mk3' size='340' side='right' caption='[[2mk3]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2mk3' size='340' side='right' caption='[[2mk3]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [http://pdbe.org/2mk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mk3 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [http://pdbe.org/2mk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk3 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:49, 11 September 2015

OCA — Fri, 11 Sep 2015 06:49:55 GMT

←Older revision		Revision as of 06:49, 11 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mk3 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [http://pdbe.org/2mk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mk3 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 13:		Line 13:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2mk3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:48, 3 January 2015

OCA — Sat, 03 Jan 2015 22:48:42 GMT

←Older revision		Revision as of 22:48, 3 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_2mk3\| PDB=2mk3 \| SCENE= }}~~	+	==Solution NMR structure of gp41 ectodomain monomer on a DPC micelle==
-	===Solution NMR structure of gp41 ectodomain monomer on a DPC micelle===	+	<StructureSection load='2mk3' size='340' side='right' caption='[[2mk3]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~{{ABSTRACT_PUBMED_24550514}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2mk3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MK3 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mk3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mk3 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The envelope glycoprotein gp41 mediates the process of membrane fusion that enables entry of the HIV-1 virus into the host cell. The actual fusion process involves a switch from a homotrimeric prehairpin intermediate conformation, consisting of parallel coiled-coil helices, to a postfusion state where the ectodomains are arranged as a trimer of helical hairpins, adopting a six-helix bundle (6HB) state. Here, we show by solution NMR spectroscopy that a water-soluble 6HB gp41 ectodomain binds to zwitterionic detergents that contain phosphocholine or phosphatidylcholine head groups and phospholipid vesicles that mimic T-cell membrane composition. Binding results in the dissociation of the 6HB and the formation of a monomeric state, where its two alpha-helices, N-terminal heptad repeat (NHR) and C-terminal heptad repeat (CHR), become embedded in the lipid-water interface of the virus and host cell. The atomic structure of the gp41 ectodomain monomer, based on NOE distance restraints and residual dipolar couplings, shows that the NHR and CHR helices remain mostly intact, but they completely lose interhelical contacts. The high affinity of the ectodomain helices for phospholipid surfaces suggests that unzippering of the prehairpin intermediate leads to a state where the NHR and CHR helices become embedded in the host cell and viral membranes, respectively, thereby providing a physical force for bringing these membranes into close juxtaposition before actual fusion.

-	~~==About this Structure==~~	+	Dissociation of the trimeric gp41 ectodomain at the lipid-water interface suggests an active role in HIV-1 Env-mediated membrane fusion.,Roche J, Louis JM, Grishaev A, Ying J, Bax A Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3425-30. doi:, 10.1073/pnas.1401397111. Epub 2014 Feb 18. PMID:24550514<ref>PMID:24550514</ref>
-	~~[[2mk3]] is a~~ 1 ~~chain structure~~. ~~Full experimental information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2MK3 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024550514</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Bax, A.]]	+	== References ==
-	[[Category: Grishaev, A.]]	+	<references/>
-	[[Category: Louis, J M.]]	+	__TOC__
-	[[Category: Roche, J.]]	+	</StructureSection>
-	[[Category: Ying, J.]]	+	[[Category: Bax, A]]
		+	[[Category: Grishaev, A]]
		+	[[Category: Louis, J M]]
		+	[[Category: Roche, J]]
		+	[[Category: Ying, J]]
	[[Category: Core]]		[[Category: Core]]
	[[Category: Gp41 ectodomain]]		[[Category: Gp41 ectodomain]]

OCA at 08:46, 19 March 2014

OCA — Wed, 19 Mar 2014 08:46:59 GMT

←Older revision		Revision as of 08:46, 19 March 2014
Line 1:		Line 1:
	{{STRUCTURE_2mk3\| PDB=2mk3 \| SCENE= }}		{{STRUCTURE_2mk3\| PDB=2mk3 \| SCENE= }}
	===Solution NMR structure of gp41 ectodomain monomer on a DPC micelle===		===Solution NMR structure of gp41 ectodomain monomer on a DPC micelle===
		+	{{ABSTRACT_PUBMED_24550514}}

	==About this Structure==		==About this Structure==
	[[2mk3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA].		[[2mk3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024550514</ref><references group="xtra"/><references/>
	[[Category: Bax, A.]]		[[Category: Bax, A.]]
	[[Category: Grishaev, A.]]		[[Category: Grishaev, A.]]

OCA at 17:40, 19 February 2014

OCA — Wed, 19 Feb 2014 17:40:25 GMT

←Older revision		Revision as of 17:40, 19 February 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_2mk3\| PDB=2mk3 \| SCENE= }}
		+	===Solution NMR structure of gp41 ectodomain monomer on a DPC micelle===

-	~~The entry~~ 2mk3 is ~~ON HOLD~~	+	==About this Structure==
-		+	[[2mk3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK3 OCA].
-	~~Authors~~: ~~Roche~~, J., Louis, J.M., ~~Grishaev, A~~., Ying, J.~~, Bax, A.~~	+	[[Category: Bax, A.]]
-		+	[[Category: Grishaev, A.]]
-	~~Description~~: ~~Solution NMR structure of gp41~~ ectodomain ~~monomer on a DPC micelle~~	+	[[Category: Louis, J M.]]
		+	[[Category: Roche, J.]]
		+	[[Category: Ying, J.]]
		+	[[Category: Core]]
		+	[[Category: Gp41 ectodomain]]
		+	[[Category: Hiv-1 env]]
		+	[[Category: Immune system]]
		+	[[Category: Membrane fusion]]
		+	[[Category: Pre-hairpin]]

OCA: Protected "2mk3" [edit=sysop:move=sysop]

OCA — Wed, 29 Jan 2014 06:34:20 GMT

Protected "2mk3" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:34, 29 January 2014