2ml1 - Revision history

OCA at 06:07, 15 May 2024

OCA — Wed, 15 May 2024 06:07:01 GMT

←Older revision		Revision as of 06:07, 15 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [https://pdbe.org/2ml1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ml1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ml1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [https://pdbe.org/2ml1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ml1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ml1 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:00, 8 March 2023

OCA — Wed, 08 Mar 2023 08:00:37 GMT

←Older revision		Revision as of 08:00, 8 March 2023
Line 1:		Line 1:

	==Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase==		==Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase==
-	<StructureSection load='2ml1' size='340' side='right'caption='[[2ml1~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='2ml1' size='340' side='right'caption='[[2ml1]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_478 Atcc 478~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Azotobacter_vinelandii Azotobacter vinelandii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">algE6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=354 ATCC 478])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [https://pdbe.org/2ml1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ml1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ml1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [https://pdbe.org/2ml1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ml1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ml1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ALGE6_AZOVI ALGE6_AZOVI]] Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat.	+	[https://www.uniprot.org/uniprot/ALGE6_AZOVI ALGE6_AZOVI] Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 478~~]]	+	[[Category: Azotobacter vinelandii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aachmann~~, F L~~]]	+	[[Category: Aachmann FL]]
-	[[Category: Buchinger, E]]	+	[[Category: Buchinger E]]
-	[[Category: Wimmer, R]]	+	[[Category: Wimmer R]]
-	~~[[Category: Alginate c-5 epimerase]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Mannuronan c-5 epimerase]]~~	+
-	~~[[Category: R-module~~]]	+

OCA at 15:16, 2 June 2021

OCA — Wed, 02 Jun 2021 15:16:38 GMT

←Older revision		Revision as of 15:16, 2 June 2021
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	==Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase==		==Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase==
-	<StructureSection load='2ml1' size='340' side='right' caption='[[2ml1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='2ml1' size='340' side='right'caption='[[2ml1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_478 Atcc 478]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_478 Atcc 478]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">algE6 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=354 ATCC 478])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">algE6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=354 ATCC 478])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [~~http~~://pdbe.org/2ml1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ml1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ml1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [https://pdbe.org/2ml1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ml1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ml1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ALGE6_AZOVI ALGE6_AZOVI]] Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat.	+	[[https://www.uniprot.org/uniprot/ALGE6_AZOVI ALGE6_AZOVI]] Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 478]]		[[Category: Atcc 478]]
		+	[[Category: Large Structures]]
	[[Category: Aachmann, F L]]		[[Category: Aachmann, F L]]
	[[Category: Buchinger, E]]		[[Category: Buchinger, E]]

OCA at 22:37, 9 August 2018

OCA — Thu, 09 Aug 2018 22:37:30 GMT

←Older revision		Revision as of 22:37, 9 August 2018
Line 1:		Line 1:
		+
	==Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase==		==Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase==
	<StructureSection load='2ml1' size='340' side='right' caption='[[2ml1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2ml1' size='340' side='right' caption='[[2ml1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_478 Atcc 478]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [http://pdbe.org/2ml1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ml1 PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">algE6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=354 ATCC 478])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [http://pdbe.org/2ml1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ml1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ml1 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 478]]
	[[Category: Aachmann, F L]]		[[Category: Aachmann, F L]]
	[[Category: Buchinger, E]]		[[Category: Buchinger, E]]

OCA at 05:26, 10 September 2015

OCA — Thu, 10 Sep 2015 05:26:24 GMT

←Older revision		Revision as of 05:26, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ml1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [http://pdbe.org/2ml1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ml1 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 2ml1" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:57, 24 December 2014

OCA — Wed, 24 Dec 2014 10:57:28 GMT

←Older revision		Revision as of 10:57, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ml1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ml1 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ALGE6_AZOVI ALGE6_AZOVI]] Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
-	~~Isotopically labelled, (13)~~C/(15)~~N from of recombinant subunit of~~ the ~~first R~~-~~module from alginate C5~~-~~epimerase 6~~ (~~AlgE6R1~~) from ~~Azotobacter vinelandii mannuronan C5~~-~~epimerase was produced~~. ~~We report here~~ the (1)H, (15)N, ~~(13)C resonance assignment~~ of ~~this subunit~~ from AlgE6 epimerase.	+	The bacterium Azotobacter vinelandii produces a family of seven secreted and calcium-dependent mannuronan C-5 epimerases (AlgE1-7). These epimerases are responsible for the epimerization of beta-d-mannuronic acid (M) to alpha-l-guluronic acid (G) in alginate polymers. The epimerases display a modular structure composed of one or two catalytic A-modules and from one to seven R-modules having an activating effect on the A-module. In this study, we have determined the NMR structure of the three individual R-modules from AlgE6 (AR1R2R3) and the overall structure of both AlgE4 (AR) and AlgE6 using small angle x-ray scattering. Furthermore, the alginate binding ability of the R-modules of AlgE4 and AlgE6 has been studied with NMR and isothermal titration calorimetry. The AlgE6 R-modules fold into an elongated parallel beta-roll with a shallow, positively charged groove across the module. Small angle x-ray scattering analyses of AlgE4 and AlgE6 show an overall elongated shape with some degree of flexibility between the modules for both enzymes. Titration of the R-modules with defined alginate oligomers shows strong interaction between AlgE4R and both oligo-M and MG, whereas no interaction was detected between these oligomers and the individual R-modules from AlgE6. A combination of all three R-modules from AlgE6 shows weak interaction with long M-oligomers. Exchanging the R-modules between AlgE4 and AlgE6 resulted in a novel epimerase called AlgE64 with increased G-block forming ability compared with AlgE6.

-	~~1H, 15N, 13C resonance assignment~~ of the ~~AlgE6R1 subunit~~ from ~~the~~ Azotobacter vinelandii ~~mannuronan C5-epimerase~~.,~~Aachmann FL~~, Skjak-Braek G ~~Biomol NMR Assign~~. ~~2008 Dec~~;2(2):~~123~~-5. doi: 10.~~1007~~/~~s12104-008-9101-0~~. Epub ~~2008~~, ~~Jul 16~~. PMID:~~19636885~~<ref>PMID:~~19636885~~</ref>	+	Structural and Functional Characterization of the R-modules in Alginate C-5 Epimerases AlgE4 and AlgE6 from Azotobacter vinelandii.,Buchinger E, Knudsen DH, Behrens MA, Pedersen JS, Aarstad OA, Tondervik A, Valla S, Skjak-Braek G, Wimmer R, Aachmann FL J Biol Chem. 2014 Nov 7;289(45):31382-96. doi: 10.1074/jbc.M114.567008. Epub 2014, Sep 29. PMID:25266718<ref>PMID:25266718</ref>

	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
Line 19:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Aachmann, F L.]]	+	[[Category: Aachmann, F L]]
-	[[Category: Buchinger, E.]]	+	[[Category: Buchinger, E]]
-	[[Category: Wimmer, R.]]	+	[[Category: Wimmer, R]]
	[[Category: Alginate c-5 epimerase]]		[[Category: Alginate c-5 epimerase]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	[[Category: Mannuronan c-5 epimerase]]		[[Category: Mannuronan c-5 epimerase]]
	[[Category: R-module]]		[[Category: R-module]]

OCA at 00:16, 2 October 2014

OCA — Thu, 02 Oct 2014 00:16:24 GMT

←Older revision		Revision as of 00:16, 2 October 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase==
		+	<StructureSection load='2ml1' size='340' side='right' caption='[[2ml1]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[2ml1]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ML1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ML1 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2ml2\|2ml2]], [[2ml3\|2ml3]], [[2pyg\|2pyg]], [[2pyh\|2pyh]], [[2agm\|2agm]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ml1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ml1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ml1 RCSB], [http://www.ebi.ac.uk/pdbsum/2ml1 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Isotopically labelled, (13)C/(15)N from of recombinant subunit of the first R-module from alginate C5-epimerase 6 (AlgE6R1) from Azotobacter vinelandii mannuronan C5-epimerase was produced. We report here the (1)H, (15)N, (13)C resonance assignment of this subunit from AlgE6 epimerase.

-	~~The entry 2ml1 is ON HOLD until Paper Publication~~	+	1H, 15N, 13C resonance assignment of the AlgE6R1 subunit from the Azotobacter vinelandii mannuronan C5-epimerase.,Aachmann FL, Skjak-Braek G Biomol NMR Assign. 2008 Dec;2(2):123-5. doi: 10.1007/s12104-008-9101-0. Epub 2008, Jul 16. PMID:19636885<ref>PMID:19636885</ref>

-	~~Authors~~: Buchinger, E., Wimmer, R.~~, Aachmann, F.L.~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii~~ Mannuronan C5-epimerase	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Aachmann, F L.]]
		+	[[Category: Buchinger, E.]]
		+	[[Category: Wimmer, R.]]
		+	[[Category: Alginate c-5 epimerase]]
		+	[[Category: Isomerase]]
		+	[[Category: Mannuronan c-5 epimerase]]
		+	[[Category: R-module]]

OCA at 08:15, 26 March 2014

OCA — Wed, 26 Mar 2014 08:15:15 GMT

←Older revision		Revision as of 08:15, 26 March 2014
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 2ml1 is ON HOLD	+	The entry 2ml1 is ON HOLD until Paper Publication

	Authors: Buchinger, E., Wimmer, R., Aachmann, F.L.		Authors: Buchinger, E., Wimmer, R., Aachmann, F.L.

	Description: Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase		Description: Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase

OCA: Protected "2ml1" [edit=sysop:move=sysop]

OCA — Mon, 03 Mar 2014 16:04:35 GMT

Protected "2ml1" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:04, 3 March 2014

OCA: New page: '''Unreleased structure''' The entry 2ml1 is ON HOLD Authors: Buchinger, E., Wimmer, R., Aachmann, F.L. Description: Solution Structure of AlgE6R1 subunit from the Azotobacter vineland...

OCA — Mon, 03 Mar 2014 16:04:33 GMT

New page: '''Unreleased structure''' The entry 2ml1 is ON HOLD Authors: Buchinger, E., Wimmer, R., Aachmann, F.L. Description: Solution Structure of AlgE6R1 subunit from the Azotobacter vineland...

New page

'''Unreleased structure'''

The entry 2ml1 is ON HOLD

Authors: Buchinger, E., Wimmer, R., Aachmann, F.L.

Description: Solution Structure of AlgE6R1 subunit from the Azotobacter vinelandii Mannuronan C5-epimerase